- High prevalence of severe mental health symptoms: depression 83.1%, anxiety 83.8%, stress 88.6%, with 56.3% extremely severe anxiety.
- Pain catastrophizing strongly correlated with psychological distress, indicating cognitive factors exacerbate chronic pain among patients.
- Findings call for integrated, trauma-informed pain management addressing both biomedical and psychosocial factors in conflict-affected populations.
Sci Rep. 2026 May 22. doi: 10.1038/s41598-026-53197-w. Online ahead of print.
ABSTRACT
This cross-sectional study examined chronic pain, mental health, and pain catastrophizing among 272 Palestinian patients at Al-Shifa Hospital in Gaza. Participants (median age 43; 57.7% female) completed assessments using the depression, anxiety, and stress (DASS-21) and pain catastrophizing (PCS) scales. Most were married (78.7%), unemployed (50%), and lived on <1,974 ILS/month (94.1%). Lower limb pain (26.8% knee) predominated, with a median pain duration of 4 years. High rates of mental health symptoms were observed: depression (83.1%), anxiety (83.8%), and stress (88.6%), with 56.3% showing extremely severe anxiety. Pain catastrophizing correlated strongly with psychological distress. Findings highlight the need for integrated, trauma-informed pain management addressing both biomedical and psychosocial factors in conflict-affected populations. Future research should explore how sociopolitical stressors and catastrophic thinking interact to exacerbate pain experiences in humanitarian crises.
PMID:42173989 | DOI:10.1038/s41598-026-53197-w
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