Psychiatric Presentation of Wilson’s Disease: A Rare Disease With an Unusual Manifestation

Cureus. 2025 Apr 3;17(4):e81645. doi: 10.7759/cureus.81645. eCollection 2025 Apr.

ABSTRACT

Wilson’s disease is a rare disorder characterized by the accumulation of copper in multiple organs. Psychiatric symptoms are somewhat common but can take many different forms, which complicates their identification. We present a case where suicidal ideation and severe sleep disturbance were the central symptoms of the initial presentation. This case shows how psychiatric symptoms in uncompensated Wilson’s disease can look like and how they are managed, as well as a psychological perspective into therapy nonadherence in chronic illness.

PMID:40322335 | PMC:PMC12048889 | DOI:10.7759/cureus.81645