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Bridging the gap: Implementing BRIDGES (Brussels Resilience and Inclusion for Depression – Guidance, Exercise and Support) to shape adolescent outpatient mental health care. A pilot randomized controlled study protocol

PLoS One. 2026 Oct 27;21(10):e0360292. doi: 10.1371/journal.pone.0360292. eCollection 2026.ABSTRACTINTRODUCTION: Physical activity interventions for adolescents with depression often show limited effectiveness due to insufficient developmental tailoring,...

Berberine as a Mitochondrial Metabolic Reprogrammer in Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD): Adaptive Energetic Stress, Quality Control, and Translational Limitations

Nutrients. 2026 Oct 14;18(20):3366. doi: 10.3390/nu18203366.ABSTRACTMetabolic dysfunction-associated steatotic liver disease (MASLD) is closely linked to mitochondrial dysfunction, including altered oxidative phosphorylation, disrupted fatty-acid oxidation, redox...

The Effects of a Multi-Strain Probiotic Formulation Containing Saffron Extract and Fructooligosaccharides on Anxiety, Depressive Symptoms, Inflammatory Markers, and BDNF: A Double-Blind, Randomized, Placebo-Controlled Pilot Study

Microorganisms. 2026 Sep 25;14(10):2170. doi: 10.3390/microorganisms14102170.ABSTRACTDepression and anxiety are highly prevalent mental health conditions, with growing evidence implicating the gut-brain-immune axis in their pathophysiology. Probiotic...
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