Category: Substance Use Disorders

Basic Clin Pharmacol Toxicol. 2026 Dec;139(6):e70332. doi: 10.1111/bcpt.70332.ABSTRACTNon-medical use of prescription opioids including oxycodone is an increasing concern in Denmark, particularly among young individuals. The...

J Int AIDS Soc. 2026 Nov;29(11):e70198. doi: 10.1002/jia2.70198.ABSTRACTINTRODUCTION: In Southeast Asia, a triple syndemic of substance use, poor mental and sexual health is shaped by...

Biomed Pharmacother. 2026 Nov 12:120037. doi: 10.1016/j.biopha.2026.120037. Online ahead of print.NO ABSTRACTPMID:43020682 | DOI:10.1016/j.biopha.2026.120037

Neuroimage. 2026 Nov 11:122347. doi: 10.1016/j.neuroimage.2026.122347. Online ahead of print.ABSTRACTIn the absence of any task, spontaneous brain activity exhibits patterns that resemble those evoked by...

Bioorg Chem. 2026 Oct 27;185:110700. doi: 10.1016/j.bioorg.2026.110700. Online ahead of print.ABSTRACTOrthoflaviviruses continue to pose a growing global health burden as climate change, urbanization, and diagnostic...

Addict Behav. 2026 Nov 9;185:108905. doi: 10.1016/j.addbeh.2026.108905. Online ahead of print.ABSTRACTBACKGROUND: Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) have been associated with alcohol-related and other behavioral...

Eur Neuropsychopharmacol. 2026 Nov 10;114:113887. doi: 10.1016/j.euroneuro.2026.113887. Online ahead of print.ABSTRACTSubstance use disorders(SUDs) are intertwined with psychiatric and general medical disorders. Substances of abuse also...

Drug Alcohol Depend. 2026 Oct 31;289:113425. doi: 10.1016/j.drugalcdep.2026.113425. Online ahead of print.ABSTRACTBACKGROUND: In recent years, α2-adrenoreceptor (α2AR) agonists have become common adulterants of illicit fentanyl...

RMD Open. 2026 Nov 9;12(4):e007238. doi: 10.1136/rmdopen-2026-007238.NO ABSTRACTPMID:43003651 | DOI:10.1136/rmdopen-2026-007238

J Subst Use Addict Treat. 2026 Nov 9:210154. doi: 10.1016/j.josat.2026.210154. Online ahead of print.ABSTRACTINTRODUCTION: Overdose mortality remains a leading cause of death among adults in...

J Subst Use Addict Treat. 2026 Nov 9:210150. doi: 10.1016/j.josat.2026.210150. Online ahead of print.ABSTRACTINTRODUCTION: Risk of recurrent opioid use during buprenorphine-naloxone (bup-nx) treatment is dynamic...

J Subst Use Addict Treat. 2026 Nov 9:210152. doi: 10.1016/j.josat.2026.210152. Online ahead of print.ABSTRACTINTRODUCTION: Provider-related barriers to substance use treatment are often framed as attitudinal...

Psychiatry Res. 2026 Nov 5;367:117564. doi: 10.1016/j.psychres.2026.117564. Online ahead of print.ABSTRACTCo-occurrence of bipolar spectrum disorders (BD) and alcohol use disorder (AUD) is common and associated...

Disabil Health J. 2026 Oct 29:102205. doi: 10.1016/j.dhjo.2026.102205. Online ahead of print.ABSTRACTBACKGROUND: People with intellectual and developmental disabilities (IDD) are susceptible to substance use disorders...

Surg Obes Relat Dis. 2026 Oct 9:S1550-7289(26)00934-2. doi: 10.1016/j.soard.2026.09.028. Online ahead of print.ABSTRACTBACKGROUND: Although metabolic and bariatric surgery (MBS) is the most effective treatment for...

BMJ Open. 2026 Nov 6;16(11):e127286. doi: 10.1136/bmjopen-2026-127286.NO ABSTRACTPMID:42994934 | DOI:10.1136/bmjopen-2026-127286

BMJ Open. 2026 Nov 6;16(11):e121653. doi: 10.1136/bmjopen-2026-121653.NO ABSTRACTPMID:42994930 | DOI:10.1136/bmjopen-2026-121653

Medicine (Baltimore). 2026 Nov 6;105(45):e51510. doi: 10.1097/MD.0000000000051510.ABSTRACTEmerging evidence indicates that inflammatory mechanisms may play a key role in linking psychological disorders to cardiovascular outcomes. This...

Medicine (Baltimore). 2026 Nov 6;105(45):e51448. doi: 10.1097/MD.0000000000051448.ABSTRACTChronic obstructive pulmonary disease (COPD) and substance use disorders (SUDs) frequently coexist, yet national mortality patterns involving both conditions...

Brain Res. 2026 Nov 6:150628. doi: 10.1016/j.brainres.2026.150628. Online ahead of print.ABSTRACTPrenatal cocaine exposure (PCE) severely affects brain development, psychology, and behavior in exposed offspring, while...

Alcohol. 2026 Nov 6:107469. doi: 10.1016/j.alcohol.2026.107469. Online ahead of print.ABSTRACTAlcohol use disorder (AUD) contributes to approximately 3 million deaths worldwide each year and leads to...

Neuropharmacology. 2026 Nov 6:111255. doi: 10.1016/j.neuropharm.2026.111255. Online ahead of print.ABSTRACTA central unresolved question in addiction neuroscience is whether the cellular differences that distinguish vulnerable from...

Drug Discov Today. 2026 Nov 6:104851. doi: 10.1016/j.drudis.2026.104851. Online ahead of print.ABSTRACTLocal hydrogels can sustain stimulator of interferon genes (STING) activation, but retention alone does...

Eur J Pharmacol. 2026 Nov 6:179524. doi: 10.1016/j.ejphar.2026.179524. Online ahead of print.ABSTRACTThe failure of cancer therapy is largely driven by the remarkable capacity of tumor...

Am J Emerg Med. 2026 Oct 1;111:135-140. doi: 10.1016/j.ajem.2026.09.051. Online ahead of print.ABSTRACTBACKGROUND: Urine drug screening (UDS) is routine in trauma care, and results populate...

Dev Cogn Neurosci. 2026 Oct 30;82:101843. doi: 10.1016/j.dcn.2026.101843. Online ahead of print.ABSTRACTThe Adolescent Brain Cognitive Development (ABCD) Study provides an unprecedented opportunity to characterize adolescent...

Neoplasia. 2026 Nov 2;83:101388. doi: 10.1016/j.neo.2026.101388. Online ahead of print.ABSTRACTThe integrated stress response (ISR), a conserved cellular sentinel, is pathologically commandeered in cancer to sustain...

J Am Acad Orthop Surg Glob Res Rev. 2026 Nov 4;10(11). doi: 10.5435/JAAOSGlobal-D-25-00325. eCollection 2026 Nov 1.ABSTRACTINTRODUCTION: Pain management is a critical component of orthopaedic...

J Am Coll Health. 2026 Nov 5:1-13. doi: 10.1080/07448481.2026.2748915. Online ahead of print.ABSTRACTObjective: This study examined whether attitudes toward rape victims and rape myth acceptance...

Tob Control. 2026 Nov 4:tc-2026-060227. doi: 10.1136/tc-2026-060227. Online ahead of print.NO ABSTRACTPMID:42982584 | DOI:10.1136/tc-2026-060227

BMJ Open. 2026 Nov 4;16(11):e121256. doi: 10.1136/bmjopen-2026-121256.NO ABSTRACTPMID:42982522 | DOI:10.1136/bmjopen-2026-121256

Int J Drug Policy. 2026 Nov 4;158:105585. doi: 10.1016/j.drugpo.2026.105585. Online ahead of print.ABSTRACTBACKGROUND: Injecting-related infections are rising globally, positioning hospitals as critical environments that shape...

Biochem Biophys Res Commun. 2026 Nov 3;842:154826. doi: 10.1016/j.bbrc.2026.154826. Online ahead of print.ABSTRACTDisulfidptosis is a newly identified form of regulated cell death driven by high...

Eur Neuropsychopharmacol. 2026 Nov 4;114:113899. doi: 10.1016/j.euroneuro.2026.113899. Online ahead of print.NO ABSTRACTPMID:42981674 | DOI:10.1016/j.euroneuro.2026.113899

WMJ. 2026;125(4):498-501.ABSTRACTBACKGROUND: This pilot primary care transition program evaluated the impact of a prerelease intervention for incarcerated individuals with opioid use disorder (OUD) on linkage...

Addiction. 2026 Nov 2. doi: 10.1111/add.70630. Online ahead of print.ABSTRACTBACKGROUND AND AIM: Health officials in the United States (USA) are seeking strategies to mitigate overdose...

Ceylon Med J. 2026 Jul 16;71(2):41-47. doi: 10.4038/cmj.v71i2.10206.ABSTRACTINTRODUCTION: Methamphetamine use is an emerging public health concern in Sri Lanka, yet there is limited qualitative understanding...

Subst Use Misuse. 2026 Nov 1:1-9. doi: 10.1080/10826084.2026.2753020. Online ahead of print.ABSTRACTBACKGROUND: Childhood exposure to household substance use problems is a recognized adverse childhood experience...

Subst Use Misuse. 2026 Nov 1:1-9. doi: 10.1080/10826084.2026.2749443. Online ahead of print.ABSTRACTBACKGROUND: Substance use is a known risk factor for suicidal ideation. This study examined...

J Oral Maxillofac Surg. 2026 Nov;84(11):1705-1706. doi: 10.1016/j.joms.2026.04.027.ABSTRACTBACKGROUND: Third molar extraction is commonly performed in adolescents and young adults and may represent an early exposure...

Drug Alcohol Rev. 2026 Nov;45(7):e70287. doi: 10.1111/dar.70287.ABSTRACTBACKGROUND: Since the early 1990s there have been calls to make the opioid antagonist naloxone more widely available including...

Drug Alcohol Depend. 2026 Oct 24;289:113403. doi: 10.1016/j.drugalcdep.2026.113403. Online ahead of print.ABSTRACTBACKGROUND: Day-level motivation to limit drinking is theorized to be a proximal mechanism of...

JMIR Form Res. 2026 Oct 22;10:e89467. doi: 10.2196/89467.ABSTRACTBACKGROUND: Despite strong evidence supporting the benefits of regular physical activity (PA) for managing coronary heart disease (CHD),...

Am J Bioeth. 2026 Nov;26(11):72-74. doi: 10.1080/15265161.2026.2741303. Epub 2026 Nov 1.NO ABSTRACTPMID:42967287 | DOI:10.1080/15265161.2026.2741303

Cureus. 2026 Oct 1;18(10):e117320. doi: 10.7759/cureus.117320. eCollection 2026 Oct.ABSTRACTTobacco use remains a health and readiness concern among military personnel. In the United States Air Force...

Infect Drug Resist. 2026 Oct 27;19:651678. doi: 10.2147/IDR.S651678. eCollection 2026.ABSTRACTBrucellosis, caused by Brucella species, is a major zoonosis with global health and economic burdens. Conventional...

Prev Med Rep. 2026 Oct 21;71:103663. doi: 10.1016/j.pmedr.2026.103663. eCollection 2026 Nov.ABSTRACTThe United States continues to face a persistent maternal mortality crisis, underscoring the need to...

J Med Case Rep. 2026 Oct 29;20(1):667. doi: 10.1186/s13256-026-06419-8.ABSTRACTBACKGROUND: The practice of adding lead to opium to increase its weight resulted in lead poisoning among...

J Addict Med. 2026 Oct 29. doi: 10.1097/ADM.0000000000001772. Online ahead of print.ABSTRACTOBJECTIVES: Documented substance use disorders (SUDs) are common among hospitalized adults and contribute to...

J Addict Med. 2026 Oct 28. doi: 10.1097/ADM.0000000000001798. Online ahead of print.ABSTRACTOBJECTIVE: To determine the prevalence and factors associated with nonfatal overdose and naloxone possession...

Am Indian Alsk Native Ment Health Res. 2026;33(2):101-146. doi: 10.5820/aian.3302.2026.101.ABSTRACTAmerican Indian and Alaska Native (AI/AN) people experience high rates of opioid misuse and disproportionate barriers...

Expert Opin Drug Deliv. 2026 Oct 29:1-15. doi: 10.1080/17425247.2026.2755180. Online ahead of print.ABSTRACTINTRODUCTION: Apolipoprotein E (apoE) plays a context-dependent role in nanomedicine for central nervous...

J Pharm Sci. 2026 Oct 28:104570. doi: 10.1016/j.xphs.2026.104570. Online ahead of print.ABSTRACTSticking of active pharmaceutical ingredients (APIs) to punches and dies remains a significant challenge...

Drug Alcohol Rev. 2026 Nov;45(7):e70285. doi: 10.1111/dar.70285.ABSTRACTINTRODUCTION: Multiple jurisdictions report disproportionately elevated rates of drug-related harm in urban settings, alongside unique treatment needs in rural...

Lancet Psychiatry. 2026 Oct 28:S2215-0366(26)00310-X. doi: 10.1016/S2215-0366(26)00310-X. Online ahead of print.NO ABSTRACTPMID:42950873 | DOI:10.1016/S2215-0366(26)00310-X

Drug Alcohol Rev. 2026 Nov;45(7):e70279. doi: 10.1111/dar.70279.ABSTRACTINTRODUCTION: Intimate partner violence (IPV) is common among men with alcohol use disorder (AUD), yet the relative contributions of...

Addiction. 2026 Oct 28. doi: 10.1111/add.70634. Online ahead of print.ABSTRACTBACKGROUND AND AIMS: Harmful alcohol use is a global health problem, with deficits in impulse control,...

Addiction. 2026 Oct 28. doi: 10.1111/add.70610. Online ahead of print.ABSTRACTBACKGROUND AND AIMS: Contemporary behavioral economic theory conceptualizes addiction as an operant reinforcer pathology in which...

Injury. 2026 Oct 24;57(12):113824. doi: 10.1016/j.injury.2026.113824. Online ahead of print.ABSTRACTBACKGROUND: Opioid use disorder (OUD) is an important challenge in orthopedic trauma, where acute injury intersects...

Addict Behav. 2026 Oct 17;185:108874. doi: 10.1016/j.addbeh.2026.108874. Online ahead of print.ABSTRACTINTRODUCTION: Although psychotic symptoms are a well-known complication of classical psychostimulants, synthetic cathinones have heterogeneous...

Addict Behav. 2026 Oct 21;185:108884. doi: 10.1016/j.addbeh.2026.108884. Online ahead of print.ABSTRACTBACKGROUND: Attention to drinking beyond the binge threshold have primarily focused on young adults. Given...

Addict Behav. 2026 Oct 17;185:108882. doi: 10.1016/j.addbeh.2026.108882. Online ahead of print.ABSTRACTBACKGROUND: Electronic vapor product use has been linked to suicidal thoughts and behaviors among adolescents;...

Psychiatry Res Neuroimaging. 2026 Oct 24;364:112360. doi: 10.1016/j.pscychresns.2026.112360. Online ahead of print.ABSTRACTPrenatal alcohol exposure (PAE) can alter neurodevelopment and cause health and behavioral effects. Mental...

Eur J Pharm Biopharm. 2026 Oct 27:115267. doi: 10.1016/j.ejpb.2026.115267. Online ahead of print.ABSTRACTKetoprofen (KP), the most photosensitive non-steroidal anti-inflammatory drug, causes photocontact dermatitis attributed to...

Neuropharmacology. 2026 Oct 27:111240. doi: 10.1016/j.neuropharm.2026.111240. Online ahead of print.ABSTRACTGlucagon-like peptide-1 (GLP-1) receptor agonists have emerged as promising pharmacotherapeutics for alcohol use disorder (AUD). Here,...

J Psychiatr Res. 2026 Oct 22:S0022-3956(26)00518-2. doi: 10.1016/j.jpsychires.2026.10.036. Online ahead of print.NO ABSTRACTPMID:42934024 | DOI:10.1016/j.jpsychires.2026.10.036

Rev Mal Respir. 2026 Oct 26:S0761-8425(26)00065-3. doi: 10.1016/j.rmr.2026.08.001. Online ahead of print.ABSTRACTINTRODUCTION: In the absence of randomized phase III trial data, thymic epithelial tumors (TETs)...

CMAJ. 2026 Oct 25;198(37):E1429-E1438. doi: 10.1503/cmaj.260078.ABSTRACTBACKGROUND: Limited data exist on substance use among parents, which can have major implications for parental and child health. We...

J Pharmacol Exp Ther. 2026 Oct 1;393(11):105040. doi: 10.1016/j.jpet.2026.105040. Online ahead of print.ABSTRACTNonselective phosphodiesterase type 4 (PDE4) inhibitors (subtypes A-D) such as apremilast significantly reduce...

J Psychiatr Res. 2026 Oct 15;204:277-283. doi: 10.1016/j.jpsychires.2026.09.030. Online ahead of print.ABSTRACTOBJECTIVE: Food addiction (FA) has emerged as a potential contributor to dysfunctional eating behaviors...

Biochem Biophys Res Commun. 2026 Oct 23;841:154797. doi: 10.1016/j.bbrc.2026.154797. Online ahead of print.ABSTRACTIn response to proposed regulations on non-addictive nicotine levels in tobacco products, researchers...

Function (Oxf). 2026 Oct 23:e900042026R1. doi: 10.1152/function.90004.2026. Online ahead of print.ABSTRACTKCNQ/Kv7 channels exhibit remarkable responses to diverse small molecule modulators, and this is a potential...

Pan Afr Med J. 2026 Jun 2;54:23. doi: 10.11604/pamj.2026.54.23.23847. eCollection 2026.ABSTRACTINTRODUCTION: hypertensive disorders represent the most common medical complications in pregnancy and the leading cause...

Front Public Health. 2026 Oct 9;14:1881851. doi: 10.3389/fpubh.2026.1881851. eCollection 2026.ABSTRACTThis article argues that the persistent burden of burnout reflects a fundamental conceptual problem-burnout continues to...

Front Pain Res (Lausanne). 2026 Oct 9;7:1923943. doi: 10.3389/fpain.2026.1923943. eCollection 2026.ABSTRACTBACKGROUND: There is no general consensus on which music genre is most effective for a...

Front Psychol. 2026 Oct 9;17:1919516. doi: 10.3389/fpsyg.2026.1919516. eCollection 2026.ABSTRACTOBJECTIVE: Few studies have investigated the therapeutic alliance in treatment of patients with borderline personality disorder (BPD),...

Front Public Health. 2026 Oct 9;14:1918846. doi: 10.3389/fpubh.2026.1918846. eCollection 2026.ABSTRACTBACKGROUND: Indigenous peoples experience substantial mental health and substance use disparities while remaining underserved by conventional...

FEBS Open Bio. 2026 Oct 24. doi: 10.1002/2211-5463.70347. Online ahead of print.ABSTRACTUltra-potent synthetic opioids are powerful analgesics but also a leading cause of drug overdose...

Exp Hematol Oncol. 2026 Oct 22;15(1):108. doi: 10.1186/s40164-026-00849-2.ABSTRACTBACKGROUND: Direct RAS targeting has progressed from pharmacologic proof of concept to routine treatment for selected KRAS G12C-mutant...

Subst Abuse Treat Prev Policy. 2026 Jul 27;21(1):68. doi: 10.1186/s13011-026-00751-4.ABSTRACTBACKGROUND: Opioid use disorder (OUD) is part of the broader spectrum of substance use disorders often...

Genome Med. 2026 Jul 28;18(1):164. doi: 10.1186/s13073-026-01723-w.ABSTRACTBACKGROUND: Pre-existing psychiatric disorders have been associated with the severity of acute respiratory infections, including COVID-19, particularly in hospitalized...

J Gen Intern Med. 2026 Oct 22. doi: 10.1007/s11606-026-10829-1. Online ahead of print.ABSTRACTBACKGROUND: Alcohol use disorder (AUD) is pervasive among hospitalized adults and associated with...

Fitoterapia. 2026 Oct 23:107526. doi: 10.1016/j.fitote.2026.107526. Online ahead of print.ABSTRACTINTRODUCTION AND AIM: Epilepsy affects approximately 50 million people worldwide, and a substantial proportion of patients...

Drug Discov Today. 2026 Oct 23:104841. doi: 10.1016/j.drudis.2026.104841. Online ahead of print.ABSTRACTMalaria and neglected tropical diseases (NTDs) affect over 1 billion people worldwide. Both disease...

Ann Hepatol. 2026 Oct 23:102475. doi: 10.1016/j.aohep.2026.102475. Online ahead of print.NO ABSTRACTPMID:42918454 | DOI:10.1016/j.aohep.2026.102475

J Am Pharm Assoc (2003). 2026 Oct 23:103554. doi: 10.1016/j.japh.2026.103554. Online ahead of print.ABSTRACTBACKGROUND: American Indian and Alaska Native (AI/AN) communities experience a disproportionate burden...

Neurosci Biobehav Rev. 2026 Oct 23:107060. doi: 10.1016/j.neubiorev.2026.107060. Online ahead of print.ABSTRACTChronic pain is generally defined as pain that persists or recurs for more than...

J Affect Disord. 2026 Oct 23:122661. doi: 10.1016/j.jad.2026.122661. Online ahead of print.ABSTRACTBACKGROUND: Suicide is a major public health problem. To our knowledge, few studies have...

J Proteome Res. 2026 Oct 2;25(10):5075-5090. doi: 10.1021/acs.jproteome.5c01275.ABSTRACTEtomidate has been linked to addictive behaviors and neurotoxic and hepatotoxic effects. We established a mouse exposure model...

J Proteome Res. 2026 Oct 2;25(10):5534-5548. doi: 10.1021/acs.jproteome.6c00535.ABSTRACTErythrocyte membrane vesicles (EMVs) have emerged as promising nanocarriers for drug delivery due to their biocompatibility and immune...

West J Emerg Med. 2026 Jul 31;27(5):1321-1326. doi: 10.5811/westjem.62063.ABSTRACTINTRODUCTION: Historically, flumazenil was employed as both a diagnostic aid in unresponsive patients and as an antidote...

West J Emerg Med. 2026 Aug 26;27(5):1402-1410. doi: 10.5811/westjem.52947.ABSTRACTINTRODUCTION: Since 2019, transmission risk factors among patients diagnosed with HIV have changed, although the trends and...

West J Emerg Med. 2026 Jul 28;27(5):1374-1383. doi: 10.5811/westjem.53968.ABSTRACTINTRODUCTION: Adolescents frequently seek care in the emergency department (ED) for behavioral health emergencies. Due to national...

West J Emerg Med. 2026 Aug 6;27(5):1393-1401. doi: 10.5811/westjem.47232.ABSTRACTINTRODUCTION: Emergency departments (ED) have become important venues for hepatitis C (HCV) screening. Similarly, EDs have had...

CMAJ. 2026 Oct 18;198(36):E1407. doi: 10.1503/cmaj.260633.NO ABSTRACTPMID:42896881 | DOI:10.1503/cmaj.260633

CMAJ. 2026 Oct 18;198(36):E1427-E1428. doi: 10.1503/cmaj.260399-f.NO ABSTRACTPMID:42896876 | DOI:10.1503/cmaj.260399-f

J Am Acad Child Adolesc Psychiatry. 2026 Oct 19:S0890-8567(26)02195-7. doi: 10.1016/j.jaac.2026.10.012. Online ahead of print.NO ABSTRACTPMID:42896820 | DOI:10.1016/j.jaac.2026.10.012

J Subst Use Addict Treat. 2026 Oct 19:210143. doi: 10.1016/j.josat.2026.210143. Online ahead of print.ABSTRACTINTRODUCTION: The National Drug Abuse Treatment Clinical Trials Network (CTN) is a...

J Subst Use Addict Treat. 2026 Oct 19:210142. doi: 10.1016/j.josat.2026.210142. Online ahead of print.ABSTRACTINTRODUCTION: Opioid use disorder (OUD) during pregnancy poses significant risks for maternal...

Curr Biol. 2026 Oct 19:S0960-9822(26)01266-2. doi: 10.1016/j.cub.2026.09.057. Online ahead of print.ABSTRACTInternal states like hunger, pain, thirst, and arousal can bias behavior by affecting sensory and...