Artificial intelligence in systemic diagnostics: Applications in psychiatry, cardiology, dermatology and oral pathology

Bioinformation. 2025 Feb 28;21(2):105-109. doi: 10.6026/973206300210105. eCollection 2025.

ABSTRACT

The integration of Artificial Intelligence (AI) in to the field of medicine is offering a new-age of updated diagnostics, prediction and treatment across multiple fields, addressing systemic disease including viral infections and cancer. The fields of Oral Pathology, Dermatology, Psychiatry and Cardiology are shifting towards integrating these algorithms to improve health outcomes. AI trained on biomarkers (e.g. salivary cf DNA) has shown to uncover the genetic linkage to disease and symptom susceptibility. AI-enhanced imaging has increased sensitivity in cancer and lesion detection, as well as detecting functional abnormalities not clinically identified. The integration of AI across fields enables a systemic approach to understanding chronic inflammation, a central driver in conditions like cardiovascular disease, diabetes and neuropsychiatric disorders. We propose that through the use of imaging data with biomarkers like cytokines and genetic variants, AI models can better trace the effects of inflammation on immune and metabolic disruptions. This can be applied to the pandemic response, where AI can model the cascading effects of systemic dysfunctions, refine predictions of severe outcomes and guide targeted interventions to mitigate the multi-systemic impacts of pathogenic diseases.

PMID:40322698 | PMC:PMC12044186 | DOI:10.6026/973206300210105