A Review of Cognitive, Sleep, and Mood Changes in the Menopausal Transition: Beyond Vasomotor Symptoms

Obstet Gynecol. 2025 May 22. doi: 10.1097/AOG.0000000000005914. Online ahead of print.

ABSTRACT

Complaints of brain fog, mood changes, and sleep disruption are common in the menopause transition. These symptoms can negatively affect overall health, quality of life, productivity, and relationships. This narrative review addresses the epidemiology, underlying mechanisms, and treatment options associated with changes in cognition, mood, and sleep during the menopause transition. The goal is to help health care professionals recognize these symptoms, provide information and support to their patients, and use an evidence-based approach to managing these symptoms.

PMID:40403308 | DOI:10.1097/AOG.0000000000005914