Evidence
![](https://psychiatryai.com/wp-content/uploads/2023/04/psychiatryai_com.webp)
The LENS trial has demonstrated that fenofibrate, a drug usually used to lower cholesterol, reduces the risk of progression of diabetic retinopathy by 27%. The results were announced today at the American Diabetes Association Scientific Sessions and published in NEJM Evidence.
![Google](https://www.google.com/images/branding/googlelogo/2x/googlelogo_light_color_92x30dp.png)
![Google Keep](https://www.gstatic.com/images/branding/product/1x/keep_48dp.png)
![Share on Linkedin](https://psychiatryai.com/wp-content/uploads/2023/10/linkedin-logo-png-2048-1.png)
Estimated reading time: 1 minute(s)
Latest: Psychiatryai.com #RAISR4D Evidence
![](/wp-content/uploads/2024/04/bd462cc11bcf0bd0d0d6f1d0f8b7cd04-modified-1.png)
Cool Evidence: Engaging Young People and Students in Real-World Evidence
![](/wp-content/uploads/2024/04/bd462cc11bcf0bd0d0d6f1d0f8b7cd04-modified-1.png)
Real-Time Evidence Search [Psychiatry]
![](/wp-content/uploads/2024/04/pubmed.png)
AI Research
![](/wp-content/uploads/2024/05/Il5nR_nf_400x400-modified-1.png)
Cholesterol-lowering drug slows progression of eye disease in people with diabetes
![](https://psychiatryai.com/wp-content/uploads/2023/04/psychiatryai_com.webp)
🌐 90 Days
AI Virtual Reality Related Evidence Matrix
EXPRESS: Association of Statins with Onset and Progression of Non-Alcoholic Fatty Liver Disease in Patients with Diabetes EXPRESS: Association of Statins with Onset and Progression of Non-Alcoholic Fatty Liver Disease in Patients with Diabetes Effects of genetically proxied lipid-lowering drugs on acute myocardial infarction: a drug-target mendelian randomization study Softening the tumor matrix through cholesterol depletion breaks the physical barrier for enhanced antitumor therapy Association Between Liver Fibrosis Score and Diabetic Kidney Disease: A Retrospective Cross-Sectional Study of Hospitalized Patients Non-linear relationship between serum cholesterol levels and cognitive change among older people in the preclinical and prodromal stages of dementia: a retrospective longitudinal study in Taiwan Non-linear relationship between serum cholesterol levels and cognitive change among older people in the preclinical and prodromal stages of dementia: a retrospective longitudinal study in Taiwan Autonomous artificial intelligence versus teleophthalmology for diabetic retinopathy Pivotal role of intestinal cholesterol and nuclear receptor LXR in metabolic liver steatohepatitis and hepatocarcinoma Effects of antipsychotic medications in glucose and lipid metabolism at the fasted state in drug-naive first episode patients with psychosis after six months and three years of treatment Managing hypertriglyceridemia for cardiovascular disease prevention: Lessons from the PROMINENT trial Relationship between changes in blood glucose, glycosylated hemoglobin [HbA1c], cholesterol, and triglyceride and changes in hepatic enzymes Causal relationship between PCSK9 inhibitor and common neurodegenerative diseases: A drug target Mendelian randomization study Lifestyle and medical conditions in relation to ALS risk and progression-an introduction to the Swedish ALSrisc Study Insulin Use and The Risk of Hepatocellular Carcinoma: Insights and Implications A Non-Coronary, Peripheral Arterial Atherosclerotic Disease (Carotid, Renal, Lower Limb) in Elderly Patients-A Review PART II-Pharmacological Approach for Management of Elderly Patients with Peripheral Atherosclerotic Lesions outside Coronary… Thermal evaporation as sample preparation for silver-assisted laser desorption/ionization mass spectrometry imaging of cholesterol in amyloid tissues Associations of retinal microvascular alterations with diabetes mellitus: an OCTA-based cross-sectional study Self-reported Visual Difficulty, Age-related Eye Disease, and Neuropsychiatric Outcomes in Older Adults Metformin mitigates dementia risk among individuals with type 2 diabetes Diabetes accelerates Alzheimer's disease progression in the first year post mild cognitive impairment diagnosis Pro- and anti-inflammatory cytokines are the game-changers in childhood obesity-associated metabolic disorders (diabetes and non-alcoholic fatty liver diseases) Genetic risk of type 2 diabetes modifies the association between lifestyle and glycemic health at 5 years postpartum among high-risk women Novel artificial intelligence algorithms for diabetic retinopathy and diabetic macular edema Novel artificial intelligence algorithms for diabetic retinopathy and diabetic macular edema Precision Medicine to Redefine Insulin Secretion and Monogenic Diabetes-Randomized Controlled Trial (PRISM-RCT) in Chinese patients with young-onset diabetes: design, methods and baseline characteristics Long-term Neurobehavioral and Metabolic Outcomes in Offspring of Mothers With Diabetes During Pregnancy: A Large, Population-Based Cohort Study in Ontario, Canada Ocular biomarkers: useful incidental findings by deep learning algorithms in fundus photographs Association Between Type 1 Diabetes Mellitus and Eating Disorders: A Systematic Review and Meta-Analysis Evaluation of Artificial Intelligence Algorithms for Diabetic Retinopathy Detection: Protocol for a Systematic Review and Meta-Analysis American Psychiatric Association Opposes Efforts to Ban Diversity, Equity and Inclusion Initiatives American Psychiatric Association Opposes Efforts to Ban Diversity, Equity and Inclusion Initiatives MAFLD as part of systemic metabolic dysregulation MAFLD as part of systemic metabolic dysregulation Effectiveness of Conventional Digital Fundus Photography-Based Teleretinal Screening for Diabetic Retinopathy and Diabetic Macular Edema: A Report by the American Academy of Ophthalmology Understanding the link between different types of maternal diabetes and the onset of autism spectrum disorders Resmetirom's Approval: Highlighting the Need for Comprehensive Approaches in NASH Therapeutics Association of type 2 diabetes with family history of diabetes, diabetes biomarkers, mental and physical disorders in a Kenyan setting A neural-mast cell axis regulates skin microcirculation in diabetes A pilot cost-analysis study comparing AI-based EyeArt® and ophthalmologist assessment of diabetic retinopathy in minority women in Oslo, Norway Neutrophil/HDL-C, Lymphocyte/HDL-C and Monocyte/HDL-C in subjects with asymptomatic carotid atherosclerosis Key lifestyles and health outcomes across 16 prevalent chronic diseases: A network analysis of an international observational study Serum Vitamin D Level in Overweight Individuals and Its Correlation With the Incidence of Non-alcoholic Fatty Liver Disease Improving mental health in chronic care in general practice: study protocol for a cluster-randomised controlled trial of the Healthy Mind intervention Association of physical activity and sports participation with insulin resistance and non-alcoholic fatty liver disease in people with type 1 diabetes Evaluating the incidence of complications among people with diabetes according to age of onset: Findings from the UK Biobank Liver as a new target organ in Alzheimer's disease: insight from cholesterol metabolism and its role in amyloid-beta clearance Moderating Effect of Depression on Glycemic Control in an eHealth Intervention Among Black Youth With Type 1 Diabetes: Findings From a Multicenter Randomized Controlled Trial Moderating Effect of Depression on Glycemic Control in an eHealth Intervention Among Black Youth With Type 1 Diabetes: Findings From a Multicenter Randomized Controlled Trial Heterogeneity of glycaemic phenotypes in type 1 diabetes Complex dichotomous links of nonalcoholic fatty liver disease and inflammatory bowel disease: exploring risks, mechanisms, and management modalities Falsely low glycosylated haemoglobin levels probably secondary to hypersplenism in a patient with diabetes mellitus Development and validation of a simple and practical model for early detection of diabetic macular edema in patients with type 2 diabetes mellitus using easily accessible systemic variables Dipeptidyl peptidase 4 inhibitors vs. metformin for new-onset dementia: a propensity score-matched cohort study Phytosterols in human serum as measured using a liquid chromatography tandem mass spectrometry Eight-year nationwide study of the bidirectional association between type 2 diabetes and depression in nearly 8 million German outpatients Genetic and Lifestyle Risk Factors of Metabolic Dysfunction-Associated Fatty Liver Disease and Its Relationship with Premature Coronary Artery Disease: A Study on the Pars Cohort Diagnostic role of SPP1 and collagen IV in a rat model of type 2 diabetes mellitus with MASLD An observation study of the effect of "Internet + Nursing" on psychological status and quality of life of patients with thyroid eye disease Advancements and turning point of artificial intelligence in ophthalmology: A comprehensive analysis of research trends and collaborative networks Diabetes and obesity: the role of stress in the development of cancer Monitoring disease progression in metabolic dysfunction-associated steatotic liver disease Monitoring disease progression in metabolic dysfunction-associated steatotic liver disease Causal effect of blood osteocalcin on the risk of Alzheimer's disease and the mediating role of energy metabolism
Evidence Blueprint
Cholesterol-lowering drug slows progression of eye disease in people with diabetes
![](https://psychiatryai.com/wp-content/uploads/2023/04/psychiatryai_com.webp)
☊ AI-Driven Related Evidence Nodes
(recent articles with at least 5 words in title)
More Evidence
![](https://psychiatryai.com/wp-content/uploads/2023/04/psychiatryai_com.webp)
Cholesterol-lowering drug slows progression of eye disease in people with diabetes
🌐 365 Days
AI Virtual Reality Related Evidence Matrix
EXPRESS: Association of Statins with Onset and Progression of Non-Alcoholic Fatty Liver Disease in Patients with Diabetes EXPRESS: Association of Statins with Onset and Progression of Non-Alcoholic Fatty Liver Disease in Patients with Diabetes Effects of genetically proxied lipid-lowering drugs on acute myocardial infarction: a drug-target mendelian randomization study Softening the tumor matrix through cholesterol depletion breaks the physical barrier for enhanced antitumor therapy The effects of cholesterol and statins on Parkinson's neuropathology: a narrative review Association Between Liver Fibrosis Score and Diabetic Kidney Disease: A Retrospective Cross-Sectional Study of Hospitalized Patients In praise of pioglitazone: An economically efficacious therapy for type 2 diabetes and other manifestations of the metabolic syndrome Genetic Association of Lipids and Lipid-Lowering Drug Target Genes With Attention Deficit Hyperactivity Disorder Diabetes mellitus and the progression of non-alcoholic fatty liver disease to decompensated cirrhosis: a retrospective cohort study Cardiovascular risk management among individuals with type 2 diabetes and severe mental illness: a cohort study Dog ownership may promote cardiometabolic health in U.S. military veterans Resistance to cholesterol gallstone disease: hepatic cholesterol metabolism Fresh fruit, dried fruit, raw vegetables, and cooked vegetables consumption associated with progression trajectory of type 2 diabetes: a multi-state analysis of a prospective cohort Cholesterol Exacerbates the Pathophysiology of Non-Alcoholic Steatohepatitis by Upregulating Hypoxia-Inducible Factor 1 and Modulating Microcirculatory Dysfunction CARDIAC REHABILITATION: IMPROVING OUTCOMES FOR PATIENTS WITH HEART DISEASE Cardiovascular Disease Risk Factor Control in People With and Without Human Immunodeficiency Virus Prospective Association Between Video and Computer Game Use During Adolescence and Incidence of Metabolic Health Risks: Secondary Data Analysis Mediating role of atherogenic lipoproteins in the relationship between liver fat and coronary artery calcification Coping and risk perception during the COVID-19 pandemic in type 2 diabetes: Does it influence metabolic control? Berberine-induced glucagon-like peptide-1 and its mechanism for controlling type 2 diabetes mellitus: a comprehensive pathway review The relationship between periodic limb movement during sleep and dyslipidaemia in patients with obstructive sleep apnea Vascular complications and associated comorbidities in newly diagnosed pre-diabetes: is it the tip of the iceberg? Non-linear relationship between serum cholesterol levels and cognitive change among older people in the preclinical and prodromal stages of dementia: a retrospective longitudinal study in Taiwan Non-linear relationship between serum cholesterol levels and cognitive change among older people in the preclinical and prodromal stages of dementia: a retrospective longitudinal study in Taiwan Maternal history of Alzheimer's disease predisposes to altered serum cholesterol levels in adult offspring Autonomous artificial intelligence versus teleophthalmology for diabetic retinopathy Pivotal role of intestinal cholesterol and nuclear receptor LXR in metabolic liver steatohepatitis and hepatocarcinoma Association of non-high-density lipoprotein cholesterol trajectories with the development of non-alcoholic fatty liver disease: an epidemiological and genome-wide association study NASH drug treatment development: challenges and lessons Effects of antipsychotic medications in glucose and lipid metabolism at the fasted state in drug-naive first episode patients with psychosis after six months and three years of treatment The Impact of Diabetic Retinopathy on the Choriocapillaris in Neovascular AMD Conservative therapy and secondary prevention of PAD Managing hypertriglyceridemia for cardiovascular disease prevention: Lessons from the PROMINENT trial The association between the severity of diabetic retinopathy and cognitive impairment: a cross-sectional study Relationship between changes in blood glucose, glycosylated hemoglobin [HbA1c], cholesterol, and triglyceride and changes in hepatic enzymes The Promising Success of Project Extension for Community Healthcare Outcomes (ECHO) Diabetes: Case Series Comprehensive analysis of the clinical and biological significances of cholesterol metabolism in lower-grade gliomas Causal relationship between PCSK9 inhibitor and common neurodegenerative diseases: A drug target Mendelian randomization study Hepatic steatosis aggravates atherosclerosis via small extracellular vesicle-mediated inhibition of cellular cholesterol efflux Curcumin protects against bisphenol A-induced hepatic steatosis by inhibiting cholesterol absorption and synthesis in CD-1 mice Fatty Liver Index and mortality after myocardial infarction: A prospective analysis in the Alpha Omega Cohort Lower prevalence of elevated liver stiffness measurements in people with type 2 diabetes taking sodium-glucose co-transporter 2 inhibitors or glucagon-like peptide-1 receptor agonists TorS - Reframing a rational for type 2 diabetes treatment Lifestyle and medical conditions in relation to ALS risk and progression-an introduction to the Swedish ALSrisc Study Lipotoxicity: The missing link between diabetes and periodontitis? The Benefits of a Comprehensive Cardiac Rehabilitation Program for Patients with Acute Coronary Syndrome: A Follow-Up Study Insulin Use and The Risk of Hepatocellular Carcinoma: Insights and Implications Intestinal Pgc1α ablation protects from liver steatosis and fibrosis Diabetic foot ulcers risk prediction in patients with type 2 diabetes using classifier based on associations rule mining NAFLD Fibrosis Progression and Type 2 Diabetes: The Hepatic-Metabolic Interplay Affective and Cognitive Impairments in Rodent Models of Diabetes Rectal sensitivity correlated with gastrointestinal-mediated glucose disposal, but not the incretin effect The development and validation of the Worries About Recurrence or Progression Scale (WARPS) High-Fat Diet-Induced Diabetic Conditions Exacerbate Cognitive Impairment in a Mouse Model of Alzheimer's Disease Via a Specific Tau Phosphorylation Pattern Non-alcoholic fatty liver disease and diabetic retinopathy: Is there an association? A Non-Coronary, Peripheral Arterial Atherosclerotic Disease (Carotid, Renal, Lower Limb) in Elderly Patients-A Review PART II-Pharmacological Approach for Management of Elderly Patients with Peripheral Atherosclerotic Lesions outside Coronary… Thermal evaporation as sample preparation for silver-assisted laser desorption/ionization mass spectrometry imaging of cholesterol in amyloid tissues Isosteviol attenuates streptozotocin-mediated diabetic nephropathy in rats by upregulating and stimulating adenosine monophosphate-activated protein kinase Using Structural Equation Modelling in Routine Clinical Data on Diabetes and Depression: Observational Cohort Study Different effects of menopausal hormone therapy on non-alcoholic fatty liver disease based on the route of estrogen administration Associations of retinal microvascular alterations with diabetes mellitus: an OCTA-based cross-sectional study Relationships of Brain Cholesterol and Cholesterol Biosynthetic Enzymes to Alzheimer's Pathology and Dementia in the CFAS Population-Derived Neuropathology Cohort A Markov model of fibrosis development in Non-Alcoholic Fatty Liver Disease predicts fibrosis progression in clinical cohorts Glucokinase regulatory protein: a balancing act between glucose and lipid metabolism in NAFLD
Inoxford, university