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Chem Commun (Camb). 2024 Jul 15. doi: 10.1039/d4cc02346c. Online ahead of print.
ABSTRACT
The current opioid epidemic has incentivized the discovery of new non-addictive analgesics, a process that requires the screening of opioid receptor binding, traditionally performed using radiometric assays. Here we describe a label-free alternative based on high-throughput (1 Hz) ambient mass spectrometry for screening the receptor binding of new opioid analogues.
PMID:39007214 | DOI:10.1039/d4cc02346c
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