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Impact of childhood trauma on suicidal ideation: Sequential mediating effects of interpersonal sensitivity and interpersonal needs

J Affect Disord. 2025 May 6:S0165-0327(25)00777-3. doi: 10.1016/j.jad.2025.05.021. Online ahead of print.

ABSTRACT

BACKGROUND: The potential mediators between childhood trauma and suicidal ideation are unclear; only a few research studies have discussed interpersonal aspects as a mediator. We examined the relationships between childhood trauma, suicidal ideation, and its mediators-interpersonal sensitivity and needs-among patients diagnosed with major depressive disorder (MDD), bipolar II disorder (BP-II), and bipolar I disorder (BP-I).

METHODS: We reviewed the data of 248 patients diagnosed with MDD, 228 patients with BP-II, and 87 patients with BP-I. Childhood trauma, interpersonal sensitivity, interpersonal needs, and suicidal ideation were each measured by using the Short Form of Childhood Trauma Questionnaire, the Korean version of the Interpersonal Sensitivity Measure, the Interpersonal Needs Questionnaire-15, and the Depressive Symptom Inventory-Suicidality Subscale. Multilevel structural equation modeling was conducted to examine whether the relationships among main variables were different according to mood disorder diagnoses. Thereafter, structural equation modeling was conducted to explore the mediating roles of interpersonal sensitivity and interpersonal needs in the relationship between childhood trauma and suicidal ideation.

RESULTS: The results indicated that the relationship between childhood trauma and suicidal ideation is positively and sequentially mediated by interpersonal sensitivity and interpersonal needs, specifically perceived burdensomeness (β = 0.046, 95 % CI = [0.023, 0.070]) and thwarted belongingness (β = 0.008, 95 % CI = [0.001, 0.014]). The results revealed that there were no differences in the mechanisms among the three groups: MDD, BP-II, and BP-I (χ2(34) = 45.51, p = .09).

CONCLUSIONS: Interventions on the interpersonal aspects of individuals who have experienced childhood trauma could be beneficial for their mental health. Providing identical interventions were revealed to be effective in all the three groups of patients with different mood disorders.

PMID:40339716 | DOI:10.1016/j.jad.2025.05.021

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