Evidence
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eNeuro. 2024 Jul 1;11(7):ENEURO.0319-23.2024. doi: 10.1523/ENEURO.0319-23.2024. Print 2024 Jul.
NO ABSTRACT
PMID:38951040 | DOI:10.1523/ENEURO.0319-23.2024
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Lecanemab and Donanemab as Therapies for Alzheimer's Disease: An Illustrated Perspective on the Data Conditioning Conformity: A Neuroscientific Funding and Publishing Paradox Altered Hippocampal Activation in Seizure-Prone CACNA2D2 Knock-out Mice The granular retrosplenial cortex is necessary in male rats for object-location associative learning and memory, but not spatial working memory or visual discrimination and reversal, in the touchscreen operant chamber Sustained inhibition of GABA-AT by OV329 enhances neuronal inhibition and prevents development of benzodiazepine refractory seizures Targeted memory reactivation during non-rapid eye movement sleep enhances neutral, but not negative, components of memory Shared mechanisms drive ocular following and motion perception Activity-Dependent Ectopic Spiking in Parvalbumin-Expressing Interneurons of the Neocortex The Role of Vesicular Glutamate Transporter Type 3 in Social Behavior, with a Focus on the Median Raphe Region Facilitating the sharing of electrophysiology data analysis results through in-depth provenance capture Fine-tuning amyloid precursor protein expression through non-sense mediated mRNA decay Practical Bayesian Inference in Neuroscience: Or How I Learned To Stop Worrying and Embrace the Distribution Auditory encoding of natural speech at subcortical and cortical levels is not indicative of cognitive decline Sleep disruption precedes forebrain synaptic Tau burden and contributes to cognitive decline in a sex-dependent manner in the P301S Tau transgenic mouse model Topography and ensemble activity in auditory cortex of a mouse model of Fragile-X-Syndrome Hypothalamic-pituitary-adrenal axis dysfunction elevates SUDEP risk in a sex-specific manner Loss of sigma-2 receptor/TMEM97 is associated with neuropathic injury-induced depression-like behaviors in female mice Value-driven adaptations of mesolimbic dopamine release are governed by both model-based and model-free mechanisms Phase delays between mouse globus pallidus neurons entrained by common oscillatory drive arise from their intrinsic properties, not their coupling Tools for Cre-mediated conditional deletion of floxed alleles from developing cerebellar Purkinje cells Ventral tegmental area amylin receptor activation differentially modulates mesolimbic dopamine signaling in response to fat versus sugar Short-term memory capacity predicts willingness to expend cognitive effort for reward Comparative anatomy of the dentate mossy cells in non-human primates: their spatial distributions and axonal projections compared with mouse mossy cells Chronic social defeat stress increases brain permeability to ghrelin in male mice Structural neuroplasticity effects of singing in chronic aphasia Large Individual Differences in Functional Connectivity in the Context of Major Depression and Antidepressant Pharmacotherapy Processing language partly shares neural genetic basis with processing tools and body parts Processing language partly shares neural genetic basis with processing tools and body parts Persistent Interruption in Parvalbumin Positive Inhibitory Interneurons: Biophysical and Mathematical Mechanisms Enhanced synaptic inhibition in the dorsolateral geniculate nucleus in a mouse model of glaucoma Trauma in neonatal acute brain slices alters calcium and network dynamics and causes calpain-mediated cell death Trauma in neonatal acute brain slices alters calcium and network dynamics and causes calpain-mediated cell death Neuropeptide Modulation Enables Biphasic Inter-network Coordination via a Dual-Network Neuron Neural filtering of physiological tremor oscillations to spinal motor neurons mediates short-term acquisition of a skill learning task Theta phase-entrainment of single cell spiking in rat somatosensory barrel cortex and secondary visual cortex is enhanced during multisensory discrimination behavior Cell specific single viral vector CRISPR/Cas9 editing and genetically encoded tool delivery in the central and peripheral nervous systems Erratum: Huang et al., "Phosphoinositide 3-Kinase Gamma Contributes to Neuroinflammation in a Rat Model of Surgical Brain Injury" Unique Properties of Thalamocortical Projections to the Gustatory Cortex Including Early Career Researchers in Scientific Publishing TMS-fMRI Supports Roles for VLPFC and Downstream Regions in Cognitive Reappraisal Differences in Neural Activation between Actual Tool Use and Pantomime: Evidence for Two Different Streams? Differences in Neural Activation between Actual Tool Use and Pantomime: Evidence for Two Different Streams? Erratum: Seigneur and Sudhof, "Genetic Ablation of All Cerebellins Reveals Synapse Organizer Functions in Multiple Regions throughout the Brain" Astrocytic Control of Glutamate Spillover and Extrasynaptic NMDA Receptor Activation: Implications for Neurodegenerative Disorders The Insular Cortex→Bed Nucleus of the Stria Terminalis Pathway during Early Abstinence from Chronic Alcohol Use: A Promising Target for Mitigating Negative Emotions and Relapse Risk Neutral or detrimental effects of TREM2 agonist antibodies in preclinical models of Alzheimer's Disease and Multiple Sclerosis Development of disease-modifying therapies against Alzheimer's disease Correction: Updated safety results from phase 3 lecanemab study in early Alzheimer's disease Lecanemab blocks the effects of the Ab/fibrinogen complex on blood clots and synapse toxicity in organotypic culture Coffee and tea are unlikely to be risk factors or preventers of Alzheimer's disease or vascular dementia Predicting how many people might receive treatment with new therapies for Alzheimer's disease Inhibitory roles of Apolipoprotein E Christchurch astrocytes in curbing tau propagation using human pluripotent stem cell-derived models The network structure of cognitive impairment: from Subjective Cognitive Decline to Alzheimer's Disease Neuronal Activity in Gustatory Cortex during Economic Choice Systems genetics analyses reveals key genes related to behavioral traits in the striatum of CFW mice Mutation of the ALS/FTD-associated RNA-binding protein FUS affects axonal development A Prelimbic Cortex-Thalamus Circuit Bidirectionally Regulates Innate and Stress-induced Anxiety-like Behavior MEG evidence that modality-independent conceptual representations contain semantic and visual features A Reconsideration of the Core and Matrix Classification of Thalamocortical Projections A Reconsideration of the Core and Matrix Classification of Thalamocortical Projections G272V and P301L mutations induce isoform specific tau mislocalization to dendritic spines and synaptic dysfunctions in cellular models of 3R and 4R tau frontotemporal dementia Dopamine Release in the Nucleus Accumbens Core Encodes the General Excitatory Components of Learning A light-responsive neural circuit suppresses feeding Perineuronal nets in the rat medial prefrontal cortex alter hippocampal-prefrontal oscillations and reshape cocaine self-administration memories
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Lecanemab and Donanemab as Therapies for Alzheimer's Disease: An Illustrated Perspective on the Data Conditioning Conformity: A Neuroscientific Funding and Publishing Paradox Deathtouch: The Long and Selective Reach of Proneurotrophin Shapes Neurodegeneration after Concussive Brain Injury What N Is N-ough for MRI-Based Animal Neuroimaging? Mice Expressing A53T/A30P Mutant Alpha-Synuclein in Dopamine Neurons Do Not Display Behavioral Deficits Chronic Visual Stimulation with LED Light Flickering at 24, 40, or 80 Hz Failed to Reduce Amyloid β Load in the 5XFAD Alzheimer's Disease Mouse Model Differences in Discounting Behavior and Brain Responses for Food and Money Reward Human Brain Project Partnering Projects Meeting: Status Quo and Outlook Altered Hippocampal Activation in Seizure-Prone CACNA2D2 Knock-out Mice The granular retrosplenial cortex is necessary in male rats for object-location associative learning and memory, but not spatial working memory or visual discrimination and reversal, in the touchscreen operant chamber Sustained inhibition of GABA-AT by OV329 enhances neuronal inhibition and prevents development of benzodiazepine refractory seizures Exploring the Neural Processes behind Narrative Engagement: An EEG Study Targeted memory reactivation during non-rapid eye movement sleep enhances neutral, but not negative, components of memory Shared mechanisms drive ocular following and motion perception Activity-Dependent Ectopic Spiking in Parvalbumin-Expressing Interneurons of the Neocortex Auditory and visual gratings elicit distinct gamma responses (8 words) Customizable Open-Source Rotating Rod (Rotarod) Enables Robust Low-Cost Assessment of Motor Performance in Mice The Role of Vesicular Glutamate Transporter Type 3 in Social Behavior, with a Focus on the Median Raphe Region Facilitating the sharing of electrophysiology data analysis results through in-depth provenance capture High-Sensitivity Intrinsic Optical Signal Imaging Through Flexible, Low-Cost Adaptations of an Upright Microscope Dynamic Foraging Behavior Performance Is Not Affected by Scn2a Haploinsufficiency Fine-tuning amyloid precursor protein expression through non-sense mediated mRNA decay A Simple, Lightweight, and Low-Cost Customizable Multielectrode Array for Local Field Potential Recordings Practical Bayesian Inference in Neuroscience: Or How I Learned To Stop Worrying and Embrace the Distribution Auditory encoding of natural speech at subcortical and cortical levels is not indicative of cognitive decline Sleep disruption precedes forebrain synaptic Tau burden and contributes to cognitive decline in a sex-dependent manner in the P301S Tau transgenic mouse model Proactive Versus Reactive Control Strategies Differentially Mediate Alcohol Drinking in Male Wistar and P rats Topography and ensemble activity in auditory cortex of a mouse model of Fragile-X-Syndrome A multiscale closed-loop neurotoxicity model of Alzheimer's disease progression explains functional connectivity alterations Hypothalamic-pituitary-adrenal axis dysfunction elevates SUDEP risk in a sex-specific manner Loss of sigma-2 receptor/TMEM97 is associated with neuropathic injury-induced depression-like behaviors in female mice Single-nucleus RNA-seq characterizes the cell types along the neuronal lineage in the adult human subependymal zone and reveals reduced oligodendrocyte progenitor abundance with age Value-driven adaptations of mesolimbic dopamine release are governed by both model-based and model-free mechanisms Phase delays between mouse globus pallidus neurons entrained by common oscillatory drive arise from their intrinsic properties, not their coupling Tools for Cre-mediated conditional deletion of floxed alleles from developing cerebellar Purkinje cells Pupil size is sensitive to low-level stimulus features, independent of arousal-related modulation Ventral tegmental area amylin receptor activation differentially modulates mesolimbic dopamine signaling in response to fat versus sugar Short-term memory capacity predicts willingness to expend cognitive effort for reward Comparative anatomy of the dentate mossy cells in non-human primates: their spatial distributions and axonal projections compared with mouse mossy cells Gamma and Beta Band Oscillation in Working Memory given Sequential or Concurrent Multiple Items: A Spiking Network Model Chronic social defeat stress increases brain permeability to ghrelin in male mice Structural neuroplasticity effects of singing in chronic aphasia Additive effects of monetary loss and positive emotion in the human brain Large Individual Differences in Functional Connectivity in the Context of Major Depression and Antidepressant Pharmacotherapy Forebrain EAAT3 overexpression increases susceptibility to amphetamine-induced repetitive behaviors Mild deficits in fear learning: Evidence from humans and mice with cerebellar cortical degeneration Extrasynaptic localization is essential for α5GABAA receptor modulation of dopamine system function Processing language partly shares neural genetic basis with processing tools and body parts Processing language partly shares neural genetic basis with processing tools and body parts Single-nucleus profiling identifies accelerated oligodendrocyte precursor cell senescence in a mouse model of Down Syndrome Persistent Interruption in Parvalbumin Positive Inhibitory Interneurons: Biophysical and Mathematical Mechanisms Enhanced synaptic inhibition in the dorsolateral geniculate nucleus in a mouse model of glaucoma Trauma in neonatal acute brain slices alters calcium and network dynamics and causes calpain-mediated cell death Trauma in neonatal acute brain slices alters calcium and network dynamics and causes calpain-mediated cell death Monitoring changes in TMS-evoked EEG and EMG activity during 1 Hz rTMS of the healthy motor cortex How sucrose preference is gained and lost: An in-depth analysis of drinking behavior during the sucrose preference test in mice Neuropeptide Modulation Enables Biphasic Inter-network Coordination via a Dual-Network Neuron Neural filtering of physiological tremor oscillations to spinal motor neurons mediates short-term acquisition of a skill learning task The neural correlates of individual differences in reinforcement learning during pain avoidance and reward seeking Theta phase-entrainment of single cell spiking in rat somatosensory barrel cortex and secondary visual cortex is enhanced during multisensory discrimination behavior Food restriction level and reinforcement schedule differentially influence behavior during acquisition and devaluation procedures in mice Cell specific single viral vector CRISPR/Cas9 editing and genetically encoded tool delivery in the central and peripheral nervous systems The novel somatosensory nose-poke adapted paradigm (SNAP) is an effective tool to assess differences in tactile sensory preferences in autistic-like mice Estradiol receptors inhibit long-term potentiation in the dorsomedial striatum
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