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Challenges, barriers and opportunities for neglected tropical disease programs of conflict-affected African countries

AI Summary
  • Conflict-affected areas present multiple interacting challenges that hinder NTD programme implementation, community engagement and sustainability across endemic regions.
  • External factors, access to areas, water, sanitation and hygiene, inclusivity, stakeholder partnerships and financial resources critically shape programme effectiveness.
  • Targeted research and development of a practical framework are required to address scale and breadth of challenges and achieve global NTD goals by 2030.
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Int Health. 2026 May 8;18(3):340-351. doi: 10.1093/inthealth/ihaf149.

ABSTRACT

BACKGROUND: Insecurity and conflict threaten achievement of global neglected tropical disease (NTD) targets. Identifying conflict-associated challenges and mitigation strategies can inform NTD programmatic decision-making.

METHODS: In-depth interviews were conducted with key stakeholders to explore their experiences of implementing NTD programs in conflict-affected regions in sub-Saharan Africa. Study 1 included a variety of stakeholders in Nigeria and study 2 included the NTD program managers from multiple countries. Thematic analysis was used to identify and extract key themes.

RESULTS: Fourteen participants (seven participants per study) from six countries and several NTD programs reported an array of complex challenges that were categorised into three common program-specific activity themes (implementation, community engagement, sustainability) and five common external influencing themes (access to areas; water, sanitation and hygiene; inclusivity; stakeholder partnering; financial resources). Study 1 included a unique theme for solutions. Several common subthemes (surveillance, community education, displaced populations, access for women) and unique study 1 subthemes were reported.

CONCLUSIONS: Many complex interacting factors hinder NTD programs in conflict-affected NTD-endemic areas. The scale and breadth of the common and unique challenges and potential solutions require more investigation to enable the development of a practical framework to support programs in achieving the global NTD goals of 2030.

PMID:42101813 | DOI:10.1093/inthealth/ihaf149

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