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Different profiles of multi-dimensional symptoms and psychological characteristics and their related suicide behavior among college students with psychotic-like experiences

AI Summary
  • Latent profile analysis identified three PLEs subgroups: troubled (10.3%), vulnerable (3.0%), and symptomatic but content (32.3%) with high entropy 0.915.
  • All PLEs groups showed higher odds of suicide behaviour versus non-PLEs (OR 1.69-6.49), with population attributable fraction 42.8%.
  • Only the troubled profile predicted increased suicide behaviour after covariate adjustment (OR 2.12, 95% CI 1.37-3.28; PAF 14.7%); supports comprehensive assessment to guide prevention.
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Asian J Psychiatr. 2026 Jun 29;122:105082. doi: 10.1016/j.ajp.2026.105082. Online ahead of print.

ABSTRACT

BACKGROUND: Participants with psychotic-like experiences (PLEs) have higher suicide behavior (e.g., suicide attempts, suicide deaths), but it remains unclear which features influence suicide behavior in this population. This study aims to identify different PLEs subgroups based on multiple clinical symptoms and psychological characteristics relevant to suicidality, and examine their associations with suicide behavior.

METHODS: Among 6390 college students at baseline, 2913 screened positive for lifetime PLEs. Latent profile analysis was conducted to identify different PLEs profiles based on baseline clinical symptoms and psychological characteristics. Model fit indices guided model selection. A generalized linear model examined PLEs profile- suicide behavior associations at one-year follow-up, controlling for covariates, and the population attributable fraction (PAF) was calculated.

RESULTS: A three-profile solution was optimal (entropy = 0.915): troubled (10.3%), vulnerable (3.0%), and symptomatic but content (32.3%). Compared to the non PLEs group (54.4%), all three PLEs groups exhibited significantly higher odd of suicide behavior one year later (OR = 1.69-6.49, PAF = 42.8%). However, only the troubled PLEs group showed significant higher subsequent suicide behavior (OR=2.12, 95%CI: 1.37-3.28, PAF = 14.7%) after controlling for covariates.

CONCLUSION: PLEs exhibit heterogeneity across symptoms and psychological characteristics associated with suicide behavior. A comprehensive PLEs assessment may enhance suicide prevention efforts.

PMID:42378834 | DOI:10.1016/j.ajp.2026.105082

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