Integrating mitoepigenetics into research in mood disorders: a state-of-the-art review

27 February 2024

Evidence

Front Physiol. 2024 Feb 8;15:1338544. doi: 10.3389/fphys.2024.1338544. eCollection 2024.

ABSTRACT

Mood disorders, including major depressive disorder and bipolar disorder, are highly prevalent and stand among the leading causes of disability. Despite the largely elusive nature of the molecular mechanisms underpinning these disorders, two pivotal contributors-mitochondrial dysfunctions and epigenetic alterations-have emerged as significant players in their pathogenesis. This state-of-the-art review aims to present existing data on epigenetic alterations in the mitochondrial genome in mood disorders, laying the groundwork for future research into their pathogenesis. Associations between abnormalities in mitochondrial function and mood disorders have been observed, with evidence pointing to notable changes in mitochondrial DNA (mtDNA). These changes encompass variations in copy number and oxidative damage. However, information on additional epigenetic alterations in the mitochondrial genome remains limited. Recent studies have delved into alterations in mtDNA and regulations in the mitochondrial genome, giving rise to the burgeoning field of mitochondrial epigenetics. Mitochondrial epigenetics encompasses three main categories of modifications: mtDNA methylation/hydroxymethylation, modifications of mitochondrial nucleoids, and mitochondrial RNA alterations. The epigenetic modulation of mitochondrial nucleoids, lacking histones, may impact mtDNA function. Additionally, mitochondrial RNAs, including non-coding RNAs, present a complex landscape influencing interactions between the mitochondria and the nucleus. The exploration of mitochondrial epigenetics offers valuable perspectives on how these alterations impact neurodegenerative diseases, presenting an intriguing avenue for research on mood disorders. Investigations into post-translational modifications and the role of mitochondrial non-coding RNAs hold promise to unravel the dynamics of mitoepigenetics in mood disorders, providing crucial insights for future therapeutic interventions.

PMID:38410811 | PMC:PMC10895490 | DOI:10.3389/fphys.2024.1338544

Document this CPD Copy URL Button

Add to Google Keep

LinkedIn Share

Share on Linkedin

Estimated reading time: 5 minute(s)

Latest: Psychiatryai.com #RAISR4D

Cool Evidence: Engaging Young People and Students in Real-World Evidence ☀️

Real-Time Evidence Search [Psychiatry]

AI Research [Andisearch.com]

Integrating mitoepigenetics into research in mood disorders: a state-of-the-art review

Copy WordPress Title

🌐 90 Days

VR Related Evidence Matrix

Evidence Blueprint

Integrating mitoepigenetics into research in mood disorders: a state-of-the-art review

☊ AI-Driven Related Evidence Nodes

(recent articles with at least 5 words in title)

More Evidence

Integrating mitoepigenetics into research in mood disorders: a state-of-the-art review

🌐 365 Days

Floating Tab

CME/CPD

VR Related Evidence Matrix

Inbipolar

New Evidence

Real-Time AI PFDR Research

2019-0397: Prevention of future deaths report 31 May 2024
Date of report: 22/11/2019 Ref: 2019-0397 Deceased name: REDACTED Coroner name: Andrew Cox Coroner Area: Cornwall and the Isles of Scilly Category: Suicide (from 2015) This report is being sent to: College of Policing The post 2019-0397: Prevention of future deaths report appeared first on Courts and Tribunals Judiciary.
2018-0405: Prevention of future deaths report 31 May 2024
Date of report: 21/12/2018 Ref: 2018-0405 Deceased name: Coroner name: John Ellery Coroner Area: Shropshire, Telford and Wrekin Category: Suicide (from 2015) This report is being sent to: Midlands The post 2018-0405: Prevention of future deaths report appeared first on Courts and Tribunals Judiciary.
Hayley Cowan: Prevention of future deaths report 31 May 2024
Date of report: 29/05/2024 Ref: 2024-0291 Deceased name: Hayley Cowan Coroner name: Joanne Kearsley Coroner Area: Manchester North Category: Mental Health related deaths This report is being sent to: Ministry of Justice | Department of Health and Social Care REGULATION 28 REPORT TO PREVENT FUTURE DEATHS THIS REPORT IS BEING SENT TO: Rt Hon Victoria Atkins, Department of Health And Social Care, ...
Oliver Steeper: Prevention of future deaths report 31 May 2024
Date of report: 24/05/2024 Ref: 2024-0290 Deceased name: Oliver Steeper Coroner name: Katrina Hepburn Coroner Area: Central and South East Kent Category: Child Death (from 2015) This report is being sent to: Department for Education REGULATION 28 REPORT TO PREVENT FUTURE DEATHS THIS REPORT IS BEING SENT TO: 1. The Secretary of State for Education 1 CORONER I am Katrina Hepburn, Area Coroner, ...
Clara Winter: Prevention of future deaths report 31 May 2024
Date of report: 28/05/2024 Ref: 2024-0289 Deceased name: Clara Winter Coroner name: Kerrie Burge Coroner Area: South Wales Central Category: Hospital Death (Clinical Procedures and medical management) related deaths This report is being sent to: Cwm Taf Morgannwg University Health Board REGULATION 28 REPORT TO PREVENT FUTURE DEATHS THIS REPORT IS BEING SENT TO:The Chief Executive, Cwm Taf Morgannwg University Health Board 1 CORONER ...

...

Dance, music and creative activities combine for centenary celebration of Kafka 31 May 2024
A range of spectacular events are set to take place at venues across Oxford during May and June celebrating the literary works and global legacy of the writer, Franz Kafka 100 years after his death.
First use of weather forecasts to show human impact on extreme weather is ‘transformational’, Oxford scientists say 29 May 2024
National forecasting centres like the Met Office could apply the same tools used for weather forecasting to quantify how human behaviour is aggravating major events like floods, heatwaves and storms, climate scientists at Oxford University Physics show in a study published today in Nature Communications.
New molecule found to suppress bacterial antibiotic resistance evolution 24 May 2024
Researchers from the University of Oxford have developed a new small molecule that can suppress the evolution of antibiotic resistance in bacteria and make resistant bacteria more susceptible to antibiotics. The findings have been published in the journal Chemical Science.

Pharmacology Research Staff Society Seminar
Dr Rumaitha Al Hosni: "Pharmacological profiling of small molecule modulators of the TMEM16A channel and their implications for the control of artery and capillary function" AND Dr Daan Van Kruining: "Sphingolipid pathway expression and genetics in GBA Parkinson's Disease"
Child & Adolescent Mental Health Seminar Series: 'Findings & Learning from the national STADIA (Standardised Diagnostic Assessments in CAMHS) study – a multi-Centre Randomised Controlled Trial'
The STADIA Trial is investigating whether the use of the Development and Wellbeing Assessment (DAWBA) questionnaire helps support the referral and assessment processes within the Child and Adolescent Mental Health Services (CAMHS) and helps clinicians identify emotional disorders in children and young people. Find out more: https://www.nctu.ac.uk/our-research/randomised-trials/current-studies/stadia.aspx This is an online seminar (Zoom). Please email […]
Safeguarding in times of crisis. The compensation of the former Bavarian royal family after 1918
In November 1918, the monarchy of Bavaria was abolished after a successful democratic revolution. Immediately afterwards, the question was raised on how to deal with the House of Wittelsbach in the future and whether and if so, what financial compensation they could expect. The property disputes between the representatives of the Free State of Bavaria […]

Oxford Union believes the House of Lords is not fit for power 1 June 2024
On Thursday night, the Oxford Union passed the motion “This House believes the House of Lords is not fit for power" with 90 members in favour and 85 against.
The Oxford Student
Creative Writing: This House 1 June 2024
Sophie Harrison shares her creative poem, This House
The Oxford Student
Why I don’t have Instagram: Being invisible in the social media age 1 June 2024
“You must be the one who doesn’t have Instagram.” This was how my college brother greeted me when we first met in freshers’ week.
The Oxford Student

Study outlines feasibility of multiple disease risk prediction model for primary care 23 May 2024
Forecasting how best to control and eliminate Neglected Tropical Diseases 26 April 2024
Neglected tropical diseases (NTDs) are a major cause of death, disability, and economic hardship worldwide, particularly in low- and middle-income countries. While many of these diseases are targeted for control, elimination, or eradication by 2030, achieving those targets will be challenging due to disruptions to programmes related to the COVID-19 pandemic and differences in disease […]
Revised ultrasound protocols required for diagnosing liver diseases associated with schistosomiasis 21 March 2024

New small molecule found to suppress the evolution of antibiotic resistance in bacteria 28 May 2024
Researchers from the Ineos Oxford Institute for antimicrobial research (IOI) and the Department of Pharmacology at Oxford University, have developed a new small molecule that can suppress the evolution of antibiotic resistance in bacteria and make resistant bacteria more susceptible to antibiotics.
University of Oxford research receives £5 million funding boost from British Heart Foundation 24 May 2024
Funding will support world-leading cardiovascular disease research.
Hiding in plain sight: study identifies cryptic disease-causing genetic variants not detected by standard testing 23 May 2024
Researchers in Oxford have identified types of genetic variants that lead to a range of rare disease but are not picked up by standard genetic testing.

Congratulations to Linxin Li 27 March 2024
Who has been awarded a prestigious fellowship.
World Sleep Day 15 March 2024
Friday the 15th March marked World Sleep Day. To celebrate, we put on some fascinating, interactive public engagement events.
New online tool for child anxiety could expand access to child mental health services 7 February 2024
New research from the University of Oxford has revealed that an online programme that empowers parents to apply Cognitive Behavioural Therapy (CBT) principles in their child’s day to day lives is just as effective as traditional talking therapies for child anxiety problems.

Statin use among people with depression associated with lower mortality 30 May 2024
New study of more than one million people with depression in England shows that statin use is associated with lower mortality and no increased adverse events.
Addressing homelessness could help prevent violence – new study 29 May 2024
Addressing homelessness should be a focus of public health initiatives in high income countries to help prevent violence, according to a new paper published in The Lancet Public Health.
Three new Associate Professors appointed 14 May 2024
Rob McCutcheon, Vanessa Raymont and Andrea Reinecke have all been conferred the title Associate Professor by the Medical Sciences Division.

Measurement Invariance of the Higher-Order Model of Preschool Anxiety Scale (PAS) across Child Age, Gender, Parental Anxiety, and Pandemic Period in England 31 May 2024
The Preschool Anxiety Scale (PAS) is a parent-report scale measuring young children’s anxiety symptoms involving five specific anxiety symptoms (separation anxiety, physical injury fears, social phobia, obsessive-compulsive disorder, generalised anxiety) that load on a higher-order factor representing general anxiety shared by all specific anxiety symptom subtypes. Although the PAS has been widely used to assess […]
Managing well-being in paediatric critical care: a multiperspective qualitative study of nurses' and allied health professionals' experiences. 31 May 2024
OBJECTIVES: It is well evidenced that healthcare professionals working in paediatric critical care experience high levels of burn-out, compassion fatigue and moral distress. This worsened during the COVID-19 pandemic. This work examines the nature of challenges to workplace well-being and explores what well-being means to staff. This evidence will inform the development of staff interventions […]
Psychosis as a disorder of muscarinic signalling: psychopathology and pharmacology. 31 May 2024
Dopaminergic receptor antagonism is a crucial component of all licensed treatments for psychosis, and dopamine dysfunction has been central to pathophysiological models of psychotic symptoms. Some clinical trials, however, indicate that drugs that act through muscarinic receptor agonism can also be effective in treating psychosis, potentially implicating muscarinic abnormalities in the pathophysiology of psychosis. Here, […]

Functional Connectivity-Based Searchlight Multivariate Pattern Analysis for Discriminating Schizophrenia Patients and Predicting Clinical Variables 31 May 2024
AbstractBackground. Schizophrenia, a multifaceted psychiatric disorder characterized by functional dysconnectivity, poses significant challenges in clinica
OUP Academic
Unraveling the Concept of Childhood Adversity in Psychosis Research: A Systematic Review 30 May 2024
AbstractBackground. During the last decades, an abundance of studies has investigated childhood adversity in relation to psychosis. This systematic review
OUP Academic
Unraveling the Prefrontal Cortex-Basolateral Amygdala Pathway’s Role on Schizophrenia’s Cognitive Impairments: A Multimodal Study in Patients and Mouse Models 30 May 2024
AbstractBackground and Hypothesis. This study investigated the role of the medial prefrontal cortex (mPFC)-basolateral amygdala (BLA) pathway in schizophre
OUP Academic

Comprehensive review confirms mask effectiveness against respiratory infections, urges better design and policy support 22 May 2024
New comprehensive review provides strong evidence that masks and respirators effectively reduce the transmission of respiratory infections like COVID-19, based on analysis of over 400 studies from multiple disciplines.
World hypertension day: How we’re tackling high blood pressure from pregnancy to later life 17 May 2024
For World Hypertension Day 2024, discover three of our innovative studies – SNAP2, SHIP, and OPTIMISE 2 – aiming to improve blood pressure management across the life cycle through technology and patient involvement.
Ground-breaking art exhibition, The PANORAMIC PRINCIPLE, unveiled at Celebratory Symposium 19 April 2024
The PANORAMIC PRINCIPLE art exhibition, by CTU artist-in-residence Tanya Poole, was unveiled at the PRINCIPLE-PANORAMIC Celebratory Symposium this week. The portraits interpret the human experience of conducting and participating in the trials and honour the diverse array of participants, researchers, and medical professionals whose inclusive efforts set global benchmarks and transformed lives.

Cambridge Laboratory for Research into Autism | 1 June 2024
1 Jun 2024: The Autism Research Centre is based in the Department of Psychiatry, University of Cambridge.
Cognition and Motivated Behaviour Lab | Department of Psychology 1 June 2024
1 Jun 2024: Search site. Cognition and Motivated Behaviour Lab. Department of Psychology. Welcome to CAMBLab. Our Reseach. Find out more about research in the Cognition and Motivated Behaviour Lab. . Read more at: Participate In Our Research!. Participate In
MPhil in Medical Science (Psychiatry) | Postgraduate Study 1 June 2024
1 Jun 2024: Search site. MPhil in Medical Science (Psychiatry). Postgraduate Study. MPhil in Medical Science (Psychiatry). ... the opportunity to gain knowledge of the broader field of research in psychiatry; and.

How to Handle the Sunday Scaries 31 May 2024
Our bloggers share advice for anyone feeling anxious on Sunday. Check out their tips for school burnout, anxiety and managing worries about the week ahead.
YoungMinds
Words Matter: Debunking Stereotypes About OCD 28 May 2024
Laura understands how OCD stigmas make it harder to recognise symptoms and get the right support. She shares her experience to help debunk the stereotypes.
YoungMinds
How to Manage PCOS Symptoms at Work 23 May 2024
Rose shares her experience of polycystic ovary syndrome (PCOS) and mental health, the importance of self-care, and getting the support you deserve at work.
YoungMinds

Restrictive visa policies harm global scientific exchanges 2 June 2024
Lancet. 2024 Jun 1;403(10442):2376. doi: 10.1016/S0140-6736(24)00300-3. NO ABSTRACT PMID:38823985 | DOI:10.1016/S0140-6736(24)00300-3
Restrictive visa policies harm global scientific exchanges 2 June 2024
Lancet. 2024 Jun 1;403(10442):2376. doi: 10.1016/S0140-6736(24)00300-3. NO ABSTRACT PMID:38823985 | DOI:10.1016/S0140-6736(24)00300-3
Preparing Trainees for Public Health Advocacy Through Community Partnerships 2 June 2024
Child Adolesc Psychiatr Clin N Am. 2024 Jul;33(3):447-456. doi: 10.1016/j.chc.2024.02.010. Epub 2024 Apr 5. ABSTRACT This article reviews the existing literature related to medical training in public advocacy and provides the reader with several training examples to consider in a child and adolescent psychiatry fellowship or in combined training programs. Advocacy training embedded within community, […]
Gastroesophageal reflux disease and non-alcoholic fatty liver disease: a two-sample Mendelian randomization combined with meta-analysis 2 June 2024
Sci Rep. 2024 Jun 2;14(1):12633. doi: 10.1038/s41598-024-63646-z. ABSTRACT Accumulating evidence from observational studies have suggested an association between gastroesophageal reflux disease (GERD) and non-alcoholic fatty liver disease (NAFLD). However, due to that such studies are prone to biases, we imported Mendelian randomization (MR) to explore whether the causal association between two diseases exsit. Hence, we […]
Advancing Youth Justice: The Child and Adolescent Psychiatrist’s Role 2 June 2024
Child Adolesc Psychiatr Clin N Am. 2024 Jul;33(3):397-409. doi: 10.1016/j.chc.2024.03.006. Epub 2024 Apr 16. ABSTRACT Child and adolescent psychiatrists (CAPs) play a crucial role beyond the provision of clinical care. CAPs are uniquely placed to understand and help patients navigate the fine line among psychiatric care, health and well-being, and the laws and policies supporting […]

Care challenges and silver linings in HIV and behavioral health service delivery for individuals living with HIV and severe mental illness during the COVID-19 pandemic: a qualitative study
Though COVID-19 presented several complex barriers to care for providers serving patients with comorbid HIV and SMI, the increased flexibility afforded by telehealth and a greater focus on collaborative approaches to patient care may benefit this patient population in the future. Additionally, the f …
PubMed
The impact of intimate partner violence on PrEP adherence among U.S. Cisgender women at risk for HIV
NCT02584140 (ClinicalTrials.gov), registered 15/10/2015.
PubMed
Intervening in the Premonitory Phase to Prevent Migraine: Prospects for Pharmacotherapy
Migraine is a common brain condition characterised by disabling attacks of headache with sensory sensitivities. Despite increasing understanding of migraine neurobiology and the impacts of this on therapeutic developments, there remains a need for treatment options for patients underserved by curren …
PubMed

A Pharmacogenomics-Based In Silico Investigation of Opioid Prescribing in Post-operative Spine Pain Management and Personalized Therapy 29 May 2024
A Pharmacogenomics-Based In Silico Investigation of Opioid Prescribing in Post-operative Spine Pain Management and Personalized TherapyAuthorsKai-Uwe LewandrowskiAlireza SharafshahJohn Elfaret al.Source InformationDecember 2024, Volume44(Issue1) - Cellular and Molecular NeurobiologyResults snippetAbstract Considering the variability in individual responses to opioids and the growing concerns about opioid addiction, prescribing opioids for postoperative pain management after spine surgery presents significant challenges. […]
Ameliorative properties of quercetin in the treatment of traumatic brain injury: a mechanistic review based on underlying mechanisms 28 May 2024
Ameliorative properties of quercetin in the treatment of traumatic brain injury: a mechanistic review based on underlying mechanismsAuthorsGolale TanhaiAmir Modarresi ChahardehiMohammad Ali Sohrabiet al.Source InformationDecember 2024, Volume51(Issue1) - Molecular Biology ReportsResults snippetTraumatic brain injury (TBI) is a leading cause of disability worldwide, with an estimated annual incidence of 27–69 million. TBI is a severe condition that […]
Endothelial PDGF-D contributes to neurovascular protection after ischemic stroke by rescuing pericyte functions 22 May 2024
Endothelial PDGF-D contributes to neurovascular protection after ischemic stroke by rescuing pericyte functionsAuthorsMaxime BernardRomain MenetSarah Lecordieret al.Source InformationDecember 2024, Volume81(Issue1) - Cellular and Molecular Life SciencesResults snippetIschemic stroke induces neovascularization of the injured tissue as an attempt to promote structural repair and neurological recovery. Angiogenesis is regulated by pericytes that potently react to ischemic stroke […]

Bridging Policy and Research for Suicide Prevention in the Americas: A Joint PAHO/NIMH Symposium on Suicide Prevention 13 June 2024
The Pan American Health Organization (PAHO) and the National Institute of Mental Health (NIMH) are organizing a two-day symposium on suicide prevention, a key priority of the Americas' public health agenda.
National Institute of Mental Health
Workshop: Promoting Mental Health for Sexual and Gender Minority Youth: Evidence-Based Developmental Perspectives 10 June 2024
This two-day virtual workshop convenes researchers, youth advocates, and federal officials to review the state of the science on developmental trajectories of gender identity and sexuality with a focus on research aimed at the promotion of mental health for sexual and gender minority youth.
National Institute of Mental Health
NIMH Genomics Team 75th Anniversary Webinar: Celebrating Advancements in Psychiatric Genomics 10 June 2024
As part of the yearlong 75th Anniversary celebration, the National Institute of Mental Health (NIMH) is hosting a webinar to explore key advances in genetics and genomics research.
National Institute of Mental Health

Caring for Hospitalized Patients with Opioid Use Disorder
A panel of experts lays out best practices and notes the challenges posed by the rise of illicit fentanyl.
Neil H. Winawer, MD, SFHM
Do GLP-1 Agonists Cause Severe Depression?
Despite many anecdotes in the popular media, no good evidence supports an association yet.
Abigail Zuger, MD
Routine Screening for Depression in Primary Care: A Randomized Trial
Screening plus explicit feedback to patients and clinicians didn't appear to improve outcomes.
Peter Roy-Byrne, MD,Allan S. Brett, MD

The Reliability of Traumatic and Adverse Experiences—Reply 1 May 2024
In Reply We thank Dr Weems for his interest in our study. In a cohort study of 1196 individuals followed up to age 40 years, we found that the subjective experience of childhood maltreatment measured through retrospective self-report at age 29 years was associated with the number of subsequent follow-up phases when participants met the […]
Prioritizing Maternal Mental Health in Addressing Morbidity and Mortality 1 May 2024
This Special Communication reviews data about associations between maternal mortality and perinatal mental conditions, social determinants of health, suicide and addictive disorders, access limitations, and prenatal stress and describes efforts involving cross-disciplinary education and intervention sites and models.
The Reliability of Traumatic and Adverse Experiences 1 May 2024
To the Editor Danese and Widom reported a study of children aged 6 years who had a court-substantiated case of abuse and demographically matched children aged 6 years who did not. When the children were aged 26 years, their subjective report of exposure to abuse was assessed. The study includes data on the long-term reliability […]

Preventing suicide in people who experience incarceration 1 June 2024
No abstract
Stuart A Kinner
Worldwide incidence of suicides in prison: a systematic review with meta-regression analyses 1 June 2024
BACKGROUND: Suicide is a leading cause of death during imprisonment. This systematic review aimed to synthesise available evidence of prison suicide incidence worldwide.
Adrian P Mundt
Psychosis as a disorder of muscarinic signalling: psychopathology and pharmacology 25 May 2024
Dopaminergic receptor antagonism is a crucial component of all licensed treatments for psychosis, and dopamine dysfunction has been central to pathophysiological models of psychotic symptoms. Some clinical trials, however, indicate that drugs that act through muscarinic receptor agonism can also be effective in treating psychosis, potentially implicating muscarinic abnormalities in the pathophysiology of psychosis. Here, […]
Robert A McCutcheon

EPA-EUFAMI-GAMIAN-Europe Manifestos: a “Trilogue of Health” to advance Mental Health in Europe 29 April 2024
On the occasion of its 40th anniversary, the EPA unveiled its EU Election Manifesto. Intended as a testament to the EPA’s enduring commitment to advancing mental health care in Europe, the Manifesto outlines the EPA’s vision and objectives in view... The post EPA-EUFAMI-GAMIAN-Europe Manifestos: a “Trilogue of Health” to advance Mental Health in Europe appeared […]
Ines Goetz
Best of Research – Discover how world experts have changed their daily practice! 6 April 2024
We are pleased to announce that the Best Of Research Sessions is now available to all EPA Members for free. World experts in their field have presented papers of major importance that introduced material change to what they did clinically: Anxiety... The post Best of Research – Discover how world experts have changed their daily practice! […]
Sarah Mathern
Applications for the 2024 Summer School are now officially open! 22 March 2024
Young psychiatrists from all around Europe are invited to participate in this intensive programme with renowned experts in suicidology, including interactive discussions, role plays and workshops. Find your mentors and deepen your knowledge of the topic by sharing experience with... The post Applications for the 2024 Summer School are now officially open! appeared first on […]
Sarah Mathern

Comparing the World Psychiatric Association and European Psychiatric Association Codes of Ethics: Discrepancies and shared grounds 7 May 2024
BackgroundCodes of ethics provide guidance to address ethical challenges encountered in clinical practice. The harmonization of global, regional, and national codes of ethics is important to avoid gaps and discrepancies.MethodsWe compare the European Psychiatric Association (EPA) and the World Psychiatric Association (WPA) Codes of Ethics, addressing main key points, similarities, and divergences.ResultsThe WPA and EPA […]
Sansone, Noemi
Treatment condition as a moderator and change in trait mindfulness as a mediator of a brief mindfulness ecological momentary intervention for generalized anxiety disorder 7 May 2024
BackgroundTheories propose that judgment of and reactivity to inner experiences are mediators of the effect of mindfulness-based interventions on generalized anxiety disorder (GAD). However, no study has tested such theories using brief, mindfulness ecological momentary intervention (MEMI). We thus tested these theories using a 14-day MEMI versus self-monitoring app (SM) control for GAD.MethodsParticipants (N = 110) completed […]
Zainal, Nur Hani
The relationship between obsessive–compulsive symptoms and real-life functioning in schizophrenia: New insights from the multicenter study of the Italian Network for Research on Psychoses 29 April 2024
BackgroundAlthough obsessive–compulsive disorder (OCD) is highly prevalent in schizophrenia, its relationship with patients’ real-life functioning is still controversial.MethodsThe present study aims at investigating the prevalence of OCD in a large cohort of non-preselected schizophrenia patients living in the community and verifying the relationship of OCD, as well as of other psychopathological symptoms, with real-life functioning […]
Tonna, Matteo

BJB volume 48 issue 3 Cover and Back matter 28 May 2024
Why choose BJPsych Bulletin? 28 May 2024
BJPsych Bulletin was first established as the Bulletin of the Royal College of Psychiatrists in 1977. Since then, it has extended its influence within the field, and it is now the go-to journal for practical clinical considerations in psychiatry, and mental health more widely. It stands together with the wider family of RCPsych journals – […]
Forrester, Andrew
Authors’ Reply: In the liminal spaces of mental health law – what to do when section 136 expires? 28 May 2024
Hassanally, Khalil

BJA volume 30 issue 3 Cover and Front matter 26 April 2024
BJA volume 30 issue 3 Cover and Back matter 26 April 2024
Are community-based interventions effective at improving mental health outcomes in refugee children and adolescents in high-income countries? 26 April 2024
Multiple epidemiological studies have shown an increased prevalence of adverse mental health outcomes in refugee populations and have highlighted children and adolescents to be particularly at risk. This commentary considers a Cochrane Review examining the efficacy of community-based interventions at improving the mental health of refugee children and adolescents in high-income countries. The review concludes […]
Singh, Gracy

Biomarkers of neurodegeneration in schizophrenia: systematic review and meta-analysis 25 May 2024
Question Does neurodegenerative disease underlie the increased rate of dementia observed in older people with schizophrenia? Several studies have reported a higher prevalence of dementia in people with schizophrenia compared with the general population. This may reflect a higher risk of developing neurodegenerative diseases such as vascular dementia or Alzheimer’s disease (AD). Alternatively, this may […]
Wilson, J. C., Liu, K. Y., Jones, K., Mahmood, J., Arya, U., Howard, R.
Hypersexuality in neurological disorders: A systematic review 22 May 2024
Background Hypersexuality (HS) accompanying neurological conditions remains poorly characterized despite profound psychosocial impacts. Objective We aimed to systematically review the literature on HS in patients with neurological disorders. Study selection and analysis We conducted a systematic review to identify studies that reported HS in neurological disorders. HS was defined as a condition characterized by excessive […]
Tayim, N., Barbosa, P., Panicker, J.
Mortality and adverse events associated with statin use in primary care patients with depression: a real-world, population-based cohort study 21 May 2024
Background New National Institute for Health and Care Excellence (NICE) guidance endorses the prescription of statins in larger population groups for the prevention of cardiovascular and cerebrovascular morbidity and mortality, especially in people with severe mental illness. However, the evidence base for their safety and risk/benefit balance in depression is not established. Objectives This study […]
De Giorgi, R., De Crescenzo, F., Ostinelli, E. G., Cowen, P. J., Harmer, C. J., Fazel, S., Cipriani, A.

Biomarkers of neurodegeneration in schizophrenia: systematic review and meta-analysis 25 May 2024
Question Does neurodegenerative disease underlie the increased rate of dementia observed in older people with schizophrenia? Several studies have reported a higher prevalence of dementia in people with schizophrenia compared with the general population. This may reflect a higher risk of developing neurodegenerative diseases such as vascular dementia or Alzheimer’s disease (AD). Alternatively, this may […]
Wilson, J. C., Liu, K. Y., Jones, K., Mahmood, J., Arya, U., Howard, R.
Hypersexuality in neurological disorders: A systematic review 22 May 2024
Background Hypersexuality (HS) accompanying neurological conditions remains poorly characterized despite profound psychosocial impacts. Objective We aimed to systematically review the literature on HS in patients with neurological disorders. Study selection and analysis We conducted a systematic review to identify studies that reported HS in neurological disorders. HS was defined as a condition characterized by excessive […]
Tayim, N., Barbosa, P., Panicker, J.
Mortality and adverse events associated with statin use in primary care patients with depression: a real-world, population-based cohort study 21 May 2024
Background New National Institute for Health and Care Excellence (NICE) guidance endorses the prescription of statins in larger population groups for the prevention of cardiovascular and cerebrovascular morbidity and mortality, especially in people with severe mental illness. However, the evidence base for their safety and risk/benefit balance in depression is not established. Objectives This study […]
De Giorgi, R., De Crescenzo, F., Ostinelli, E. G., Cowen, P. J., Harmer, C. J., Fazel, S., Cipriani, A.

Association between the frontoparietal network, clinical symptoms and treatment response in individuals with untreated anorexia nervosa 28 May 2024
Background Anorexia nervosa (AN) has been characterised as a psychiatric disorder associated with increased control. Currently, it remains difficult to predict treatment response in patients with AN. Their cognitive abilities are known to be resistant to treatment. It has been established that the frontoparietal control network (FPCN) is the direct counterpart of the executive control […]
He, Q., Zheng, H., Zhang, J., Yue, L., Kang, Q., Lian, C., Guo, L., Chen, Y., Hu, Y., Wang, Y., Peng, S., Wang, Z., Liu, Q., Chen, J.
Public perspectives on AI diagnosis of mental illness 22 May 2024
O'Connor, C.
Circadian rhythm dysfunction and psychopathology in the offspring of parents with bipolar disorder: a high-risk study in the Chinese population 22 May 2024
Background Understanding the evolution of circadian rhythm dysfunction and psychopathology in the high-risk population has important implications for the prevention of bipolar disorder. Nevertheless, some of the previous studies on the emergence of psychopathologies and circadian dysfunction among high-risk populations were inconsistent and limited. Aims To examine the prevalence rates of sleep and circadian dysfunctions, […]
Lei, B., Feng, H., Yang, L., Wang, J., Chen, J., Song, W., Jiang, C., Zhang, K., Wang, Q., Tsang, J. C. C., Chan, N. Y., Liu, Y., Chan, J. W. Y., Pan, J., Zhang, B., Li, T., Merikangas, K. R., Zhang, J., Wing, Y. K.

Guidelines for the development and validation of patient-reported outcome measures: a scoping review 23 May 2024
ObjectiveThe objectives of this scoping review were to provide an overview of existing guidelines for the development and validation of patient-reported outcome measures (PROMs), review them for comprehensiveness and clarity and provide recommendations for their use based on the goals of the instrument developers.DesignScoping review.MethodsA literature search was performed in PubMed, Scopus, PsycInfo and Google […]
Jung, A., Challoumas, D., Pagels, L., Armijo-Olivo, S., Braun, T., Luedtke, K.
Clinician and health service interventions to reduce the greenhouse gas emissions generated by healthcare: a systematic review 23 May 2024
ObjectiveTo synthesise the available evidence on the effects of interventions designed to improve the delivery of healthcare that reduces the greenhouse gas (GHG) emissions of healthcare.DesignSystematic review and structured synthesis.Search sourcesCochrane Central Register of Controlled Trials, PubMed, Web of Science and Embase from inception to 3 May 2023.Selection criteriaRandomised, quasi-randomised and non-randomised controlled trials, interrupted […]
Pickles, K., Haas, R., Guppy, M., O'Connor, D. A., Pathirana, T., Barratt, A., Buchbinder, R.
Pilot study on large language models for risk-of-bias assessments in systematic reviews: A(I) new type of bias? 23 May 2024
Risk-of-bias (RoB) assessment is used to assess randomised control trials for systematic errors. Developed by Cochrane, it is considered the gold standard of assessing RoB for studies included within systematic reviews, representing a key part of Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines.1 The RoB tool comprises six domains that may signify bias: […]
Barsby, J., Hume, S., Lemmey, H. A., Cutteridge, J., Lee, R., Bera, K. D.

Psychometrics of the Korean Version of the screen for adult anxiety related disorders (SCAARED) 30 May 2024
For enhanced management of anxiety disorders, early screening and accurate diagnostic differentiation are essential. The Screen for Adult Anxiety Related Disorders (SCAARED) has been developed to identify and ...
Inae Hwang, Sanghoon Chin, Seongjun Mun, Min Ju You, Woori Moon and Silvia Kyungjin Lho
The association between anxiety and internet addiction among left-behind secondary school students: the moderating effect of social support and family types 30 May 2024
The left-behind children (LBC), children and adolescents aged 0–18 whose parents have migrated for economic purposes for extended periods exceeding three months, present a unique social concern. These children...
Siwei Miao, Lu Xu, Sihong Gao, Cuiping Bai, Yan Huang and Bin Peng
Suicide and depressive symptoms possible correlates among a sample of Egyptian physicians: observational cross-sectional study (online survey) 30 May 2024
Compared to other occupations, physicians are more susceptible to depression and suicide. Suicide among physicians in some countries reached up to 1.5- to threefold higher than the general population. However,...
Mohamed A. Khalil, Dalia Khalifa, Rasha Mahmoud Allam, Shaimaa Abdalaleem Abdalgeleel and Ola Osama Khalaf

Genome-Wide Association Study of Treatment-Resistant Depression: Shared Biology With Metabolic Traits 15 May 2024
American Journal of Psychiatry, Ahead of Print.
JooEun Kang
Long-Term Course of Remission and Recovery in Psychotic Disorders 15 May 2024
American Journal of Psychiatry, Volume 181, Issue 6, Page 532-540, June 01, 2024.
Sara Tramazzo
Pharmacogenomic Clinical Support Tools for the Treatment of Depression 30 April 2024
American Journal of Psychiatry, Ahead of Print.
Matthew L. Baum

APA/APAF Announce 2024 Awardees of MOORE Equity in Mental Health Community Grants Program 30 May 2024
Today the American Psychiatric Association (APA) and the APA Foundation announced 10 new grantees in the Moore Equity in Mental Health Community Grants Program, for a total of $100,000 disbursed. Established in 2021, the grants support community organizations that have undertaken innovative awareness programs and/or have provided services to improve the mental health of young […]
APAPsychiatric
APA Publishing Authors Win Creative Scholarship Award for Anthology on Racism and Mental Health 28 May 2024
The Society for the Study of Psychiatry and Culture has recognized American Psychiatric Association Publishing contributors Donna Norris M.D., and Annelle Primm, M.D., M.P.H., with the 2024 Creative Scholarship Award for the publication of “Mental Health, Racism, and Contemporary Challenges of Being Black in America” (2024).
APAPsychiatric
New Polling Data Shows Most Employers Offer Some Form of Mental Health Benefits, But Burnout Impacts 22 May 2024
A survey fielded last month by the American Psychiatric Association (APA) found that most working adults know how to access mental health care services through work (67%). Despite this, two-in-five employed adults worry about retaliation or being fired if they take time off for their mental health (44%) or seek mental health care (39%).
APAPsychiatric

RCPsych President responds to PM's announcement on reform of the fit note process
We are disappointed that the Prime Minister used his speech to conflate those suffering with a mental illness with a ‘sick note culture’. This language dismisses the reality of mental illness, which is concerning given the associated poor quality of life and increased mortality rates.
www.rcpsych.ac.uk
Up to 1,200 new mums suffer from psychosis each year
The Royal College of Psychiatrists is highlighting the importance of mental health before, during and after pregnancy to mark Maternal Mental Health Awareness Week.
www.rcpsych.ac.uk
"Without support it can be difficult to make a full recovery and return to employment" says RCPsych President
Dr Lade Smith CBE has called for people who have anxiety and depression to be given better and faster access to talking therapies and other forms of mental health support.
www.rcpsych.ac.uk

Computer-Based Training for Cognitive Behavioural Therapy for Substance Use Disorder: A Randomized Controlled Trial Including Quantitative and Qualitative Health and Economic Outcomes: Formation informatisée pour la thérapie cognitivo-comportementale pour les troubles liés à l'usage de substances : un essai randomisé contrôlé y compris les résultats quantitatifs et qualitatifs en matière de santé et d’économie 24 May 2024
The Canadian Journal of Psychiatry, Ahead of Print. ObjectivesHeavy alcohol and drug use is reported by a substantial number of Canadians; yet, only a minority of those experiencing substance use difficulties access specialized services. Computer-Based Training for Cognitive Behavioural Therapy (CBT4CBT) offers a low-cost method to deliver accessible and high-quality CBT for substance use difficulties. […]
Alina Patel
Evaluation des Troubles Cognitifs Chez des Patients Tunisiens Atteints de Trouble Bipolaire en Rémission : Étude Cas-Témoins: Assessment of Cognitive Impairment in Tunisian Patients With Bipolar Disorder in Remission: A Case-Control Study 24 May 2024
The Canadian Journal of Psychiatry, Ahead of Print. AbrégéObjectifsNos objectifs étaient d’évaluer les troubles cognitifs chez des patients bipolaires en rémission comparativement à des témoins sains et d’étudier leur rapport avec les facteurs cliniques et thérapeutiques.MéthodesIl s’agissait d’une étude cas-témoins, menée auprès de patients atteints de trouble bipolaire (TBP) en rémission et de témoins sains […]
Nada Charfi
Effects of Trauma Cue Exposure and Posttraumatic Stress Disorder (PTSD) on Affect and Cannabis Craving in Cannabis Users With Trauma Histories: Use of Expressive Writing as an Online Cue-Reactivity Paradigm: Effets de l'exposition aux signaux traumatiques et du SSPT sur l'affect et le besoin de cannabis chez les consommateurs de cannabis ayant des antécédents de traumatismes : utilisation de l'écriture expressive comme paradigme de réactivité en ligne 16 May 2024
The Canadian Journal of Psychiatry, Ahead of Print. ObjectivesPosttraumatic stress disorder (PTSD) and cannabis use disorder (CUD) commonly co-occur. Conditioned associations between psychological trauma cues, distress, cannabis use, and desired relief outcomes may contribute to the comorbidity. These conditioned associations can be studied experimentally by manipulating trauma cue exposure in a cue-reactivity paradigm (CRP) and […]
Sarah DeGrace

Constructive conversations on CanMEDS revisions 20 May 2024
Send us a Text Message.On this episode of the CMAJ Podcast, Dr. Blair Bigham and Dr. Mojola Omole discuss the heated debate over proposed updates to the CanMEDS framework. The controversy ignited when an interim report placed principles of equity, social justice, and anti-racism at the heart of the framework, rather than medical expertise.Dr. Kannin […]
Canadian Medical Association Journal
Navigating the complex relationship between palliative care and MAiD 6 May 2024
Send us a Text Message.On this episode of the CMAJ Podcast, Dr. Blair Bigham and Dr. Mojola Omole explore the intricate relationship between medical assistance in dying (MAiD) and palliative care in Canada. They focus on a qualitative study titled "Perspectives of Canadian healthcare leaders on the relationship between medical assistance in dying and palliative […]
Canadian Medical Association Journal
Confronting the high stakes of incivility in health care 22 April 2024
Send us a Text Message.On this episode of the CMAJ Podcast, Dr. Eve Purdy makes it clear what’s at stake when it comes to incivility in medicine. "It's very simple. Incivility kills patients, and that needs to be the single line of every healthcare leader responsible for managing and leading teams.” Dr. Purdy joins Dr. […]
Canadian Medical Association Journal

Time for a change to clozapine haematological monitoring 31 May 2024
Australasian Psychiatry, Ahead of Print. ObjectivesThis paper critiques the haematological monitoring guidelines for clozapine. It describes the history of clozapine, as well as the pathophysiology and epidemiology of clozapine-induced neutropenia (CIN) and agranulocytosis (CIA). The paper appraises the extant literature on mandatory clozapine haematological monitoring.ConclusionContemporary Australian protocols for clozapine haematological monitoring are not consistent with […]
Adrian Cheng
Trichotillomania: A perspective from bibliometric analysis 29 May 2024
Australasian Psychiatry, Ahead of Print. Aim: Trichotillomania, an obsessive-compulsive-related disorder, is defined by the recurrent act of pulling out one’s own hair from different areas of the body. Despite the considerable body of research dedicated to the subject of trichotillomania, the overarching trends that unify these studies remain obscure. The purpose of the present bibliometric […]
Emre Ertürk
Continuation or maintenance ECT for schizophrenia: A narrative review of case report data 28 May 2024
Australasian Psychiatry, Ahead of Print. ObjectiveThis review aimed to address the limited evidence on the efficacy of continuation or maintenance electroconvulsive therapy (C/M-ECT) in schizophrenia, with a focus on international case reports and series due to the scarcity of randomised controlled trials.Materials and MethodsElectronic database searches were conducted to identify case reports or series evaluating […]
Olivia Egan

The effects of inpatient suicide on nurses at Weskoppies Hospital: A qualitative study 21 May 2024
Background: Inpatient suicide is a serious adverse event in psychiatric wards. Suicide can cause severe trauma to both patients and health professionals, who may develop maladaptation with poor coping skills. Healthcare practitioners are the second victims and historically, this concept has been overlooked. The psychological effects and lack of support have not been sufficiently explored.Aim: The emotional […]
Nomthandazo Zola
Clinical profile of children and adolescents with autism spectrum disorder in Durban, South Africa 14 May 2024
Background: There are often delays in accessing care and diagnosing autism spectrum disorders (ASDs), with little data from Southern Africa on the clinical profile of affected children and adolescents.Aim: To describe the socio-demographic and clinical variables of children and adolescents with ASD attending psychiatric services at two state hospitals in eThekwini Municipality, KwaZulu-Natal province, South Africa.Setting: Two state […]
Manisharani Gangai
Views held by South African primary health care nurses on caring for people living with mental illness 3 May 2024
Background: Primary healthcare is the first point of entry into the healthcare system. Scaling up primary mental healthcare is recommended in South African mental health policy. However, there is a paucity of data exploring the views of primary healthcare nurses (PHCNs) with regards to caring for people living with mental illness (PLWMI) in South Africa.Aim: To explore […]
Nokukhanya Phungula

Standards for randomized controlled trials of efficacy of psychological treatments 10 May 2024
World Psychiatry, Volume 23, Issue 2, Page 286-287, June 2024.
David C. Mohr
The future of dynamic networks in research and clinical practice 10 May 2024
World Psychiatry, Volume 23, Issue 2, Page 288-289, June 2024.
Laura F. Bringmann
Algorithm‐based modular psychotherapy vs. cognitive‐behavioral therapy for patients with depression, psychiatric comorbidities and early trauma: a proof‐of‐concept randomized controlled trial 10 May 2024
World Psychiatry, Volume 23, Issue 2, Page 257-266, June 2024.
Elisabeth Schramm, Moritz Elsaesser, Carolin Jenkner, Martin Hautzinger, Sabine C. Herpertz

The ion channel TRPA1 is a modulator of the cocaine reward circuit in the nucleus accumbens 31 May 2024
Molecular Psychiatry, Published online: 31 May 2024; doi:10.1038/s41380-024-02623-4The ion channel TRPA1 is a modulator of the cocaine reward circuit in the nucleus accumbens
Young-Jung Kim
Beyond the serotonin deficit hypothesis: communicating a neuroplasticity framework of major depressive disorder 31 May 2024
Molecular Psychiatry, Published online: 31 May 2024; doi:10.1038/s41380-024-02625-2Beyond the serotonin deficit hypothesis: communicating a neuroplasticity framework of major depressive disorder
Chloe E. Page
Effects and safety of transcranial direct current stimulation on multiple health outcomes: an umbrella review of randomized clinical trials 30 May 2024
Molecular Psychiatry, Published online: 30 May 2024; doi:10.1038/s41380-024-02624-3Effects and safety of transcranial direct current stimulation on multiple health outcomes: an umbrella review of randomized clinical trials
Jiseung Kang

Thinking about consciousness
Can we detect consciousness in newborn infants?
Conscious experiences in infants remain poorly understood. In this NeuroView, Passos-Ferreira discusses recent evidence for and against consciousness in newborn babies. She argues that the weight of evidence from neuroimaging and behavioral studies supports the thesis that newborn infants are conscious.Conscious experiences in infants remain poorly understood. In this NeuroView, Passos-Ferreira discusses recent evidence for […]
Christof Koch
In this talk with , Christof Koch, a physicist and neuroscientist, advocates for a pragmatic program to track the footprints of consciousness in the brain and for team science, explains the recent pseudo-controversy regarding integrated information theory of consciousness, and speaks about the joy of exploring the mysteries around us.

Shifting BSMM research paradigms in the context of HIV status-neutral care continuums 30 May 2024
Nature Mental Health, Published online: 30 May 2024; doi:10.1038/s44220-024-00265-7Black sexually minoritized men (BSMM), Black men who identify as part of a sexual minority group, are disproportionately affected by HIV in the United States. There is a need to shift existing reductive research paradigms to focus on within-group variation, in order to include BSMM who are […]
John A. Schneider
Anxiety, depression and distress outcomes from the Health4Life intervention for adolescent mental health: a cluster-randomized controlled trial 23 May 2024
Nature Mental Health, Published online: 23 May 2024; doi:10.1038/s44220-024-00246-wThe authors present the secondary outcomes from a cluster-randomized controlled trial of the Health4Life multiple health behavior change intervention. The intervention showed short-term benefits for distress and depressive symptoms but was not more effective than an active control condition.
S. Smout
Psychedelic-assisted therapy among sexual and gender minority communities 23 May 2024
Nature Mental Health, Published online: 23 May 2024; doi:10.1038/s44220-024-00252-yThis Perspective discusses the importance of increasing access to psychedelic-assisted therapy to sexual and gender minorities and proposes a theoretical framework integrating minority stress theory to inform the research and guide study design.
Brady D. Hanshaw

Inflammation and immune system pathways as biological signatures of adolescent depression—the IDEA-RiSCo study 1 June 2024
Translational Psychiatry, Published online: 01 June 2024; doi:10.1038/s41398-024-02959-zInflammation and immune system pathways as biological signatures of adolescent depression—the IDEA-RiSCo study
Valentina Zonca
Multivariate brain-behaviour associations in psychiatric disorders 1 June 2024
Translational Psychiatry, Published online: 01 June 2024; doi:10.1038/s41398-024-02954-4Multivariate brain-behaviour associations in psychiatric disorders
S. Vieira
Prevalence and network structure of depression, insomnia and suicidality among mental health professionals who recovered from COVID-19: a national survey in China 30 May 2024
Translational Psychiatry, Published online: 30 May 2024; doi:10.1038/s41398-024-02918-8Prevalence and network structure of depression, insomnia and suicidality among mental health professionals who recovered from COVID-19: a national survey in China
He-Li Sun

Complete nanopore repeat sequencing of SCA27B (GAA-FGF14 ataxia) in Japanese 30 May 2024
BackgroundAlthough pure GAA expansion is considered pathogenic in SCA27B, non-GAA repeat motif is mostly mixed into longer repeat sequences. This study aimed to unravel the complete sequencing of FGF14 repeat expansion to elucidate its repeat motifs and pathogenicity.MethodsWe screened FGF14 repeat expansion in a Japanese cohort of 460 molecularly undiagnosed adult-onset cerebellar ataxia patients and […]
Miyatake, S., Doi, H., Yaguchi, H., Koshimizu, E., Kihara, N., Matsubara, T., Mori, Y., Kunieda, K., Shimizu, Y., Toyota, T., Shirai, S., Matsushima, M., Okubo, M., Wada, T., Kunii, M., Johkura, K., Miyamoto, R., Osaki, Y., Miyama, T., Satoh, M., Fujita, A., Uchiyama, Y., Tsuchida, N., Misawa, K., Hamanaka, K., Hamanoue, H., Mizuguchi, T., Morino, H., Izumi, Y., Shimohata, T., Yoshida, K., Adachi, H., Tanaka, F., Yabe, I., Matsumoto, N.
Data-driven sequence of cognitive decline in people with Parkinsons disease 30 May 2024
BackgroundUnderstanding the sequential progression of cognitive impairments in Parkinson’s disease (PD) is crucial for elucidating neuropathological underpinnings, refining the assessment of PD-related cognitive decline stages and enhancing early identification for targeted interventions. The first aim of this study was to use an innovative event-based modeling (EBM) analytic approach to estimate the sequence of cognitive declines […]
Petkus, A. J., Donahue, E., Jakowec, M. W., Bayram, E., Van Horn, J. D., Litvan, I., Petzinger, G. M., Schiehser, D. M.
Genetics of inherited peripheral neuropathies and the next frontier: looking backwards to progress forwards 24 May 2024
Inherited peripheral neuropathies (IPNs) encompass a clinically and genetically heterogeneous group of disorders causing length-dependent degeneration of peripheral autonomic, motor and/or sensory nerves. Despite gold-standard diagnostic testing for pathogenic variants in over 100 known associated genes, many patients with IPN remain genetically unsolved. Providing patients with a diagnosis is critical for reducing their ‘diagnostic odyssey’, […]
Parmar, J. M., Laing, N. G., Kennerson, M. L., Ravenscroft, G.

Mendelian randomization: causal inference leveraging genetic data 19 April 2024
Mendelian randomization (MR) leverages genetic information to examine the causal relationship between phenotypes allowing for the presence of unmeasured confounders. MR has been widely applied to unresolved questions in epidemiology, making use of summary statistics from genome-wide association studies on an increasing number of human traits. However, an understanding of essential concepts is necessary for […]
Chen, Lane G.
Interventions targeting social determinants of mental disorders and the Sustainable Development Goals: a systematic review of reviews 25 March 2024
Globally, mental disorders account for almost 20% of disease burden and there is growing evidence that mental disorders are socially determined. Tackling the United Nations Sustainable Development Goals (UN SDGs), which address social determinants of mental disorders, may be an effective way to reduce the global burden of mental disorders. We conducted a systematic review […]
Oswald, Tassia Kate
Do metacognitive therapies for schizophrenia-spectrum disorders work? A meta-analytic investigation 21 March 2024
Recent reviews and meta-analyses of metacognitive therapy for schizophrenia-spectrum disorder (SSD) have included uncontrolled studies, single-session interventions, and/or analyses limited to a single form of metacognitive therapy. We sought to evaluate the efficacy of metacognitive therapies more broadly based on controlled trials (CT) of sustained treatments. We conducted a pre-registered meta-analysis of controlled trials that […]
Melville, Grace

Digital phenotyping data and anomaly detection methods to assess changes in mood and anxiety symptoms across a transdiagnostic clinical sample 29 May 2024
Acta Psychiatrica Scandinavica, EarlyView.
Asher Cohen, John Naslund, Erlend Lane, Anant Bhan, Abhijit Rozatkar, Urvakhsh Meherwan Mehta, Aditya Vaidyam, Andrew (Jin Soo) Byun, Ian Barnett, John Torous
Electroconvulsive therapy in the maintenance phase of psychotic unipolar depression 28 May 2024
Acta Psychiatrica Scandinavica, EarlyView.
Ahmed Al‐Wandi, Mikael Landén, Axel Nordenskjöld
Somatic burden of attention‐deficit/hyperactivity disorder across the lifecourse 28 May 2024
Acta Psychiatrica Scandinavica, EarlyView.
Berit Libutzki, Benno Neukirch, Andreas Reif, Catharina A. Hartman

Social skills interventions in preschool settings: A meta‐analysis of SCR studies 1 June 2024
Psychology in the Schools, EarlyView.
Xin Dong, Mack D. Burke, Lisa Sanchez, Lisa Bowman‐Perrott
Correction to “Seizure semiology: ILAE glossary of terms and their significance” 1 June 2024
Epileptic Disorders, EarlyView.
Tracheostomy Incidence and Complications: A National Database Analysis 1 June 2024
Otolaryngology–Head and Neck Surgery, EarlyView.
William Strober, Dorina Kallogjeri, Jay F. Piccirillo, Matthew L. Rohlfing

A role for Shugoshin in human cilia?
We have recently described a novel role for the conserved centromeric/kinetochore protein and cohesin protector, Shugoshin, in cilia of C. elegans. Worms are unusual in that the sole Shugoshin protein ( SGO-1 ) is dispensable for chromosome segregation but required for cilia function in fully differentiated sensory neurons. Depletion of sgo-1 leads to an array […]
sut-2 loss of function mutants protect against tau-driven shortened lifespan and hyperactive pharyngeal pumping in a C. elegans model of tau toxicity.
Expression of human tau in C. elegans neurons causes progressive, age-associated loss of motor coordination, selective neurodegeneration, and shortened lifespan. Loss of function (LOF) mutations in the conserved gene sut-2 protects against progressive motor uncoordination and neurodegeneration in models of tauopathy. To determine whether sut-2 LOF also protects against shortened lifespan of tau transgenic C. […]
Evidence Based Clinical Analytics Supporting the Genetic Addiction Risk Severity (GARS) Assessment to Early Identify Probands in Preaddiction.
No abstract supplied.

Addressing the Youth Mental Health Epidemic
A Model for Providing Psychological Support to Healthcare Leaders and Teams in Times of Crisis
Pre-pandemic, the healthcare workforce was already at risk for higher burnout than the general population and, in some roles (e.g., physicians, nurses), at higher risk for clinical distress and suicide. Studies of healthcare workforce well-being during and after past pandemics reflect that distress can persist after a pandemic subsides, if adequate support within the workplace […]
Assessment of Brief Online Approaches for Teaching Neuroscience in Psychiatry
The goal of this study was to assess an online collection of brief educational resources (videos, case studies, articles) for teaching a broad range of concepts relating to neuroscience in psychiatry.A national sample of 52 psychiatrists enrolled in the study. Forty (77%) completed an assessment before and after having access to the educational resources for […]

Using Measurement-Based Care as a Precision Medicine Strategy for Substance Use Disorders
Precision medicine prioritizes characterization of individual patient parameters to optimize care and this review evaluates measurement-based care (MBC) as a strategy for doing so in the treatment of substance use disorders (SUD). Measurement-based care refers to the systematic use of validated assessments to inform diagnosis and treatment planning, with varying frequency of assessments. Despite the […]
Psychological Problems in the Context of Political Violence in Afghan Children
This review provides an overview of recent literature examining psychological problems in the context of political violence among Afghan children.Using recent literature (2018–2023) we identified: 1) heightened levels of psychological problems experienced by children in Afghanistan; 2) the factors associated with these psychological problems, including loss of family and community members, poverty, continuous risk of […]
Insufficient Sleep and Behavioral Health in the Military: A 5-Country Perspective
The goal of this paper was to highlight the degree to which sleep, behavioral health, and leader involvement were interrelated using data from militaries in five English-speaking countries: Australia, Canada, New Zealand, the UK, and the United States.Many service members reported sleeping fewer than the recommended 7 h/night: 34.9%, 67.2%, and 77.2% of respondents from New […]

Editorial introductions 30 May 2024
No abstract available
Time matters for mental health: a systematic review of quantitative studies on time perspective in psychiatric populations 16 May 2024
Purpose of review The ability to perform mental time travels and to develop representations of the past, the present, and the future is one of the distinctive capacities of the human mind. Despite its pronounced consequences for motivation, cognition, affect, and subjective well being, time perspective (TP) has been outside mainstream psychiatry and clinical psychology. […]
Closing the loop between environment, brain and mental health: how far we might go in real-life assessments? 15 May 2024
Purpose of review Environmental factors such as climate, urbanicity, and exposure to nature are becoming increasingly important influencers of mental health. Incorporating data gathered from real-life contexts holds promise to substantially enhance laboratory experiments by providing a more comprehensive understanding of everyday behaviors in natural environments. We provide an up-to-date review of current technological and […]

When is the best time to screen for perinatal anxiety? A longitudinal cohort study
We evaluated the best time to screen for anxiety during pregnancy or postpartum.Screening in early pregnancy was optimal to identify women with anxiety disorders.Screening in early pregnancy was optimal to identify women who wanted treatment.Screening in early pregnancy was optimal for all five screening tools evaluated.Findings can inform clinical guidelines on when to screen for […]
Daily-level associations between posttraumatic stress disorder symptoms and reactions to retrieving positive autobiographical memories
Trauma survivors with posttraumatic stress disorder (PTSD) report difficulties accessing and describing positive memories. To understand these patterns, we examined daily-level relations of PTSD symptoms with affective, cognitive (dwelling/rumination; pushing memory out of one’s mind; suppression; avoidance; distraction; thinking about something else; remembering negative or positive memories/events; negative or positive thoughts; accepting or disapproving memory; […]
Relationship between anxiety sensitivity and post-traumatic stress symptoms in trauma-exposed adults: A meta-analysis
Anxiety sensitivity are significantly correlated with PTSD symptoms with a medium effect size.Study design (cross-sectional vs. longitudinal) is found to moderate the relationship between anxiety sensitivity and PTSD.Results are consistent with cognitive models of PTSD. Given the high rate of trauma exposure among the general population, it is important to delineate the risk factors for […]

Patterns of sub‐optimal change following CBT for childhood anxiety 31 May 2024
Journal of Child Psychology and Psychiatry, EarlyView.
Lizel‐Antoinette Bertie, Kristian Arendt, Jonathan R. I. Coleman, Peter Cooper, Cathy Creswell, Thalia C. Eley, Catharina Hartman, Einar R. Heiervang, Tina In‐Albon, Karen Krause, Kathryn J. Lester, Carla E. Marin, Maaike Nauta, Ronald M. Rapee, Silvia Schneider, Carolyn Schniering, Wendy K. Silverman, Mikael Thastum, Kerstin Thirlwall, Polly Waite, Gro Janne Wergeland, Jennifer L. Hudson
Moving forward. Use of the START NOW skills training program for female youth with ODD and CD – a commentary on Stadler et al. (2024) 27 May 2024
Journal of Child Psychology and Psychiatry, EarlyView.
Gail Tripp
Hidden in plain sight: delayed ADHD diagnosis among girls and women – a commentary on Skoglund et al. (2023) 27 May 2024
Journal of Child Psychology and Psychiatry, EarlyView.
Jessica C. Agnew‐Blais

Insomnia and fibromyalgia-like symptoms among women diagnosed with relapsing remitting multiple sclerosis in Jordan: Prevalence and correlates 21 May 2024
The International Journal of Psychiatry in Medicine, Ahead of Print. ObjectiveThis study investigated the prevalence and correlates of fibromyalgia and insomnia in a sample of Women with Multiple Sclerosis (WMS).MethodsThe study was cross-sectional in design and recruited a sample of 163 women with Relapsing-Remitting Multiple Sclerosis (RRMS). Fibromyalgia was assessed using the Patient Self-Report Survey […]
Omar Gammoh
Prevalence and risk factors for chronic kidney disease among older adult patients with schizophrenia in Taiwan 20 May 2024
The International Journal of Psychiatry in Medicine, Ahead of Print. ObjectivesThere is an increasing incidence and prevalence of patients with chronic kidney disease (CKD) worldwide. Little is known the prevalence of CKD among older patients with schizophrenia. The purpose of this study was to investigate the prevalence of CKD and its risk factors in older […]
Shu-Ting Chang
All medical workers together: For better mental health and primary health care- Posters 29 April 2024
The International Journal of Psychiatry in Medicine, Volume 59, Issue 3_suppl, Page 1S-103S, May 2024.

Treating depression in patients with borderline personality disorder: clinical clues on the use of antidepressants 30 May 2024
Personality disorders (PD) are described as enduring patterns of markedly deviant and pervasive inner experiences and behaviors, with onset in adolescence, which lead to severe distress or impairment. Patients...
Carmine Tomasetti, G. Autullo, A. Ballerini, A. de Bartolomeis, B. Dell’Osso, A. Fiorentini, F. Tonioni, V. Villari and D. De Berardis
Individualized strategies for depression: narrative review of clinical profiles responsive to vortioxetine 16 May 2024
Depression is a highly heterogeneous disorder, often resulting in suboptimal response and remission rates. This underscores the need for more nuanced clinical characterization of patients to tailor individuali...
Alessandro Cuomo, Andrea Aguglia, Domenico De Berardis, Antonio Ventriglio, Camilla Gesi and Andrea Fagiolini
Measurement of perceived pressures in psychiatry: paper-and-pencil and computerized adaptive version of the P-PSY35 scale 10 May 2024
Formal coercion in psychiatry is widely studied yet much less is known about pressures patients may experience, partly because of the very few measures available. The goal of this study was to validate the P-P...
Philippe Golay, Debora Martinez, Mizué Bachelard, Benedetta Silva, Alexandra Brodard, Jonathan Perrin, Nolan Pedro Fernando, Lou-Ann Renaud, Charles Bonsack and Stéphane Morandi

Blighted phenomena: Learning to work with the dark. 8 April 2024
Blighted phenomena are understood as derivatives of dark, lonely, injured experiences—those that are often difficult to put into words. These phenomena can manifest in innumerable configurations in patients’ presentations and in the specificity of their developmental struggles and language. The present article aims to describe ways of working with the darkness of blighted experience, through […]
Intimate partner violence: Narratives of attachment relationships and linguistic analysis of emotional schemas through a quali-quantitative approach. 18 January 2024
Intimate partner violence (IPV) is a concerning, widespread issue with serious health, social, and financial consequences. Previous studies highlighted the role of insecure attachment patterns in predicting IPV victimization. This study investigates attachment classifications among women survivors of IPV referred to antiviolence centers, as determined by the Adult Attachment Interview and compare them with a […]
Review of Reading French Psychoanalysis. 25 December 2023
Reviews the book, Reading French Psychoanalysis edited by Dana Birksted-Breen, Sara Flanders, and Alain Gibeault (2010). In this essay, the author discusses eight reviews of Reading French Psychoanalysis. The reviews considered are Cheshire (2010) in the British Journal of Psychotherapy, Forde (2010) in the Revista de Psicoanálisis, Glassgold (2014) in the Psychoanalytic Quarterly, Lefer (2011) […]

Development and validation of the Gender Identity and Expression Microaggressions in Therapy Scale (GIEMTS). 18 April 2024
Developing affirming interventions for transgender and nonbinary (TNB) therapy clients requires understanding their experiences with microaggressions in psychotherapy, yet no self-report measure of anti-TNB microaggressions in this context exists. Moreover, few studies have tested the associations between anti-TNB microaggressions and therapy processes. To better address the burden of unmet mental health care needs among TNB […]
The evolution of feedback: Toward a multicultural orientation. 18 April 2024
There have been great strides in psychology regarding diversity, equity, inclusion, and multicultural competence, but a need remains to translate these values into actionable practices in psychotherapy. While the case has been made that measurement-based care is an evidence-based intervention that improves outcomes and reduces dropouts (de Jong et al., 2021) and recently that it […]
Beyond the dyad: Broadening the APA supervision guidelines to include group supervision. 28 March 2024
Group supervision is an extensively used format across many training agencies, yet it has been largely disregarded in theory and research within the supervision literature. In fact, the Guidelines for Clinical Supervision in Health Service Psychology (American Psychological Association, 2015a) mentions group supervision only one time, despite the fact that supervision within a group context […]

A Community Data Sharing Resource: The LDbase Data Repository 29 May 2024
Journal of Learning Disabilities, Ahead of Print. The purpose of this invited paper is to show the learning disabilities field what LDbase is, why it’s important for the field, what it offers the field, and examples of how you can leverage LDbase in your own work.
Sara A. Hart
Teaching Constant Rate-of-Change Problem-Solving to Secondary Students With or at Risk of Learning Disabilities 21 May 2024
Journal of Learning Disabilities, Ahead of Print. Rate of change (i.e., slope) is a critical mathematics concept for success in everyday life, academics, and professional careers. Students with or at risk of learning disabilities struggle with solving rate-of-change problems, especially word problems. Interventions that incorporate representations and problem-solving strategies are effective for improving the word […]
Kaitlin Bundock
Concept-Focused and Procedure-Focused Instruction on the Algebra Performance of Grade 9 Students With and Without Mathematics Difficulty 18 May 2024
Journal of Learning Disabilities, Ahead of Print. Developing both conceptual and procedural knowledge is important for students’ mathematics competence. This study examined whether Grade 9 general education mathematics teachers’ self-reported use of concept-focused instruction (CFI) and procedure-focused instruction (PFI) were associated differently with ninth graders’ algebra achievement after 2.5 years, depending on students’ mathematics difficulty […]
Jihyun Lee

Group identity modulates interbrain synchronization during repeated lottery contest. 11 January 2024
Overbidding in Tullock (1980) lottery contests is a robust finding in laboratory experiments. There exists plenty of evidence that demonstrates the effect of group identity on human behavior. This presents a viable avenue for mitigating or resolving the issue of overbidding. However, the impact of group identity on interbrain interactive mechanisms during lottery contests remains […]
Neurosciences tell us how to be adaptable, creative, and proactive agents in decision making: A pilot study. 7 December 2023
In organizational settings, the decision-making process plays a pivotal role and is interrelated with the capability to adapt to the context, that is, adaptability. In this study, the behavioral, electrophysiological (EEG) frequency bands (i.e., alpha, theta) and self-report correlates of adaptability in the context of decision making were explored on a sample of professionals and […]
Modulating the activity of right temporoparietal junction increased belief-based learning in an economic game. 7 December 2023
Decision making is fundamental to social and economic behavior in the presence of other competing intelligent agents. Such decisions require agents to learn about available rewards and punishments (involving reinforcement learning) and also to anticipate what opponents intend to do (involving belief-based learning). However, the neural mechanisms underlying belief-based learning are relatively poorly understood. To […]

EJIHPE, Vol. 14, Pages 1543-1560: On the Construct of Subjective Risk Intelligence and Its Relationships with Personality, Emotional Intelligence and Coping Strategies: A Comparison between Adolescents and Adults 1 June 2024
The complexity of today’s scenario has made it necessary to investigate the need for individuals to make choices that entail increasing exposure to risk and uncertainty. Among the individual resources that could help people to cope with situations of uncertainty, the new construct of subjective risk intelligence (SRI), known as a person’s ability to effectively […]
Maria Guarnera
EJIHPE, Vol. 14, Pages 1527-1542: Relationship between Parenting Educational Styles and Well-Being in Families with Autistic Children: A Systematic Review 30 May 2024
The prevalence of diagnosed cases of autism has increased rapidly, which has raised interest in studying the variables related to the well-being of these families. The purpose of this paper is to review the recent literature on other variables related to family well-being, such as parenting styles. We conducted a systematic review using the PRISMA […]
Elena Benseny Benseny Delgado
EJIHPE, Vol. 14, Pages 1514-1526: Disparity in the Burden of Caring for Older Persons between Families Living in Housing Estates and Traditional Communities in Thailand 28 May 2024
Thailand’s rapid population aging and reliance on family-based long-term care requires research into disparities in family caregiver burden. Since the type of residence matters to the caregiving outcome, this research aimed to examine the difference in caregiver burden between residents of private housing estates and traditional village communities. This cross-sectional study was conducted with 1276 […]
Nadila Mulati

Unlocking a taboo topic: the sexuality of institutionalized men within a forensic psychiatric facility 29 May 2024
.
Frédérique Fortin Jo-Annie Spearson Goulet Mathieu Goyette Ashley J. Lemieux a Department of Sexology, Université du Québec à Montréal, Canadab Research Center, Institut national de psychiatrie légale Philippe-Pinel, Montreal, Canadac Department of Psychiatry and Addiction, Université de Montréal, Canada
Evaluation of the Enhanced Engagement and Relational Support Service (EERSS) within the Offender Personality Disorder (OPD) pathway 26 May 2024
.
Bardana Singh Roxana Short Philip Minoudis a London Pathways Partnership, UKb Forensic Personality Disorder Psychology Department, East London NHS Foundation Trust, UKc Forensic and Neurodevelopmental Sciences, Kings College London, UK
Exploring the link between intelligence and drug abuse among juvenile felons in India 14 May 2024
.
Devi Sekar Mohanraj Bhuvaneswari Department of Social Sciences, School of Social Sciences and Languages, Vellore Institute of Technology, Vellore, India

Experts' decision-making processes in Swedish forensic psychiatric investigations: A case vignette study
It has previously been demonstrated that decisions made by forensic experts can suffer from issues with both bias and poor reliability. The outcome of Swedish forensic psychiatric investigations can have a major impact on the courts' choice of sanction for a mentally disordered offender. These investigations are performed by multi-professional teams of experts, where each […]
Efficiency of psychological interventions in the prevention of suicidal behavior and self-injury in penitentiary population: A systematic review
Suicidal behavior is an important public health problem, with a high prevalence in penitentiary context. Nowadays, there is a wide variety of specific treatment programs, aimed to prevent suicidal and self-injurious behavior in incarcerated people. These programs show relative efficiency depending on the model of the psychological intervention applied. This systematic review evaluates the efficiency […]
Compulsory treatment in Portuguese-speaking countries: An analysis and comparison of the legal framework
Compulsory treatment involves the hospital admission of individuals with mental disorders in appropriate facilities through judicial decisions. However, limited information is available regarding the similarities and differences in compulsory treatment legislation in Portuguese-speaking countries.To analyse the commonalities and differences in compulsory treatment legislation in Portuguese-speaking countries, where Portuguese is the primary official language, including Angola, […]

Cocaine and the port: Utopias of security, urban relations, and displacement of policing efforts in the port of Piraeus
In large commercial seaports policing and security efforts to counter the drug trade, especially cocaine, do not appear to be effective beyond a mere displacement effect. In the port of Piraeus, Greece, (perceived) rising quantities of cocaine have led to calls for further securitisation of the port to curb illicit trafficking. This article will present […]
Individual and environmental contributors to psychological distress during imprisonment
People in prison bear a higher burden of psychiatric morbidity compared with the general population. This study examined the extent to which individual and environmental factors contribute to poor mental health during imprisonment. Participants comprised 1296 randomly selected adults in 15 Belgian prisons. Psychological distress was more common in women than men and peaked during […]
Origin stories: Framing 25 years of Dutch political discourse on child sexual exploitation by tourists and travelers
Sexual exploitation of children in the context of travel and tourism (SECTT) has been described as a serious and growing problem. This study critically analyzes political debates and policy measures proposed by the Dutch government between 1995 and 2020 to combat SECTT. To understand how SECTT is framed in Dutch political discourse, Bacchi's ‘what's the […]

Correction to “Gentrification’s association with police violence and the moderating effects of race” by Harmon-Darrow et al. (2023). 2 May 2024
Reports an error in "Gentrification’s association with police violence and the moderating effects of race" by Caroline Harmon-Darrow, Hyun-Jin Jun and Charlotte Lyn Bright (Psychology of Violence, 2023[May], Vol 13[3], 183-193). In the article, corrections to some findings were needed. For the Gentrification Revitalization × Race and the Gentrification Disruption × Race interactions (reported in […]
Perceived victimhood shapes support for interpartisan political violence in the United States. 21 March 2024
Objective: Understanding the drivers of political violence is critical, given the destructive consequences it has on the fabric of society. Prior work has established the importance of situational and dispositional predictors of political violence, such as search for significance and meaning and experiencing trauma. However, these predictors do not fully account for one of its […]
Sexual victimization of autistic college students. 18 March 2024
Objective: Researchers have demonstrated a link between autism and victimization, but less research has explored rates of sexual victimization among autistic college students. Informed by lifestyle-routine activity theory, certain features of autism may enhance vulnerability to sexual victimization and may lead autistic individuals to be targeted by potential perpetrators. Method: Using data from the American […]

App-based interventions to improve cancer outcomes rely on informational support from professionals: a systematic review 17 May 2024
.
Karoline Villinger Corina Berli Urte Scholz a Department of Psychology, University of Zurich, Zurich, Switzerlandb Institute of Psychology, University of Bern, Bern, Switzerland
Tobacco use, trauma exposure and PTSD: a systematic review 7 May 2024
.
Alina Shevorykin Bridget M. Hyland Daniel Robles Mengjia Ji Darian Vantucci Lindsey Bensch Hannah Thorner Matthew Marion Amylynn Liskiewicz Ellen Carl Jamie S. Ostroff Christine E. Sheffer a Department of Health Behavior, Roswell Park Comprehensive Cancer Center, Buffalo, NY, USAb Department of Psychology, Faculty of Science, University of Alberta, Edmonton, Canadac Department of Psychology, The City College of New York (CUNY), New York, NY, USAd Department of Psychiatry and Behavioral Sciences, Memorial Sloan Kettering Cancer Center, New York, NY, USA
Development of the social dimensions of health behaviour framework 29 April 2024
.
Ryan E. Rhodes Mark R. Beauchamp a Behavioural Medicine Laboratory, School of Exercise Science, Physical and Health Education, University of Victoria, Victoria, BC, Canadab School of Kinesiology, University of British Columbia, Vancouver, BC, Canada

Mental Health First Aid™ for Deaf communities: responses to a lack of national Deaf mental health service provision 17 May 2024
For over 15 years, Mental Health First Aid™ (MHFA) has successfully been delivered in Wales, United Kingdom, with growing interest in the MHFA programme and increasing course attendees. Trainers, aware of the need for support, know the importance of MHFA being accessible for different communities and learner groups. MHFA has always focused on increasing mental […]
Julia Terry
Prevalence of cosmetic surgery and its relationship with psychosocial status: a population based study in Sulaymaniyah, Iraq 16 May 2024
This study aims to investigate the prevalence of cosmetic surgery and its relationship with the level of mental health and socioeconomic variables in Sulaymaniyah city in Iraq. This descriptive-analytical and cross-sectional study was conducted on 941 subjects who were selected using multistage sampling method. Data were collected using a checklist as well as a questionnaire. […]
Farman Zahir Abdullah
Representing the experiences of charity peer leaders facilitating well-being interventions to their peers using a constructivist grounded theory methodology 13 May 2024
This study aims to generate theory that represented charity peer leader experiences, facilitating well-being interventions to two specific groups of people: new mothers and refugees. Part 1 of this study used in-depth interviews (n = 8) and phone calls with experienced mothers (called “peer leaders”) who had facilitated well-being interventions to new mothers. These interviews […]
Jenny Burns

Cheerfulness in the history of psychiatry 28 May 2024
History of Psychiatry, Ahead of Print. In 1762, Louis-Antoine Marquis de Caraccioli (1719–1803), a prolific writer of the eighteenth century, dedicated a book to a psychological theme that medicine has forgotten: ‘gaité’ in French, which we will translate as ‘cheerfulness’. At the beginning of the nineteenth century, this work inspired two doctoral theses in medicine, […]
Olivier Walusinski
Human radiation for medicine, spiritism and hypnosis in Argentina: scientific controversies around vital radiations (1880–1930) 14 May 2024
History of Psychiatry, Ahead of Print. In the mid-nineteenth century, magnetic theories penetrated other recognized medical practices in Argentina in order to rationalize their procedures, in a culture that accepted and validated magnetism as a positive science. At the start of the twentieth century, mesmerists created a society, published books and journals, and carried out […]
Alejandro Parra
‘Eccentricity’, by DH Tuke (1892) 14 May 2024
History of Psychiatry, Volume 35, Issue 2, Page 247-252, June 2024.

An age of rage, victimhood and entitlement 1 June 2024
International Journal of Social Psychiatry, Volume 70, Issue 4, Page 636-638, June 2024.
Dinesh Bhugra
The familial transmission of suicide and non-suicidal self-injury in different income levels in town 28 May 2024
International Journal of Social Psychiatry, Ahead of Print. Background:Prior researches have established that suicide and non-suicidal self-injury (NSSI) exhibit familial transmission patterns. However, the extent to which these patterns vary across different income levels remains unclear, as well as the specific factors that influence them. This study aimed to explore these questions.Methods:We analyzed data from […]
Mei Yu
Redefining the approach to alcohol use disorder in India: A call for conventional to multidisciplinary and technologically innovative treatment strategies 20 May 2024
International Journal of Social Psychiatry, Ahead of Print.
Akhil P. Joseph

Persecution as stigma-driven trauma: Social determinants, stigma, and violence in asylum seekers in the United States
Experiences of traumatic stress are not sufficient grounds for claiming asylum.Asylees experience demographic, neighborhood, economic, environmental, and social-cultural determinants.Experiences of stigma are associated with the events of violence and trauma.Findings support conceptualizing persecution as stigma-driven trauma. Existing literature documents high rates of experienced violence in asylum seekers. Despite this high prevalence, experiences of traumatic stress […]
Superior medical resources or geographic proximity? The joint effects of regional medical resource disparity, geographic distance, and cultural differences on online medical consultation
Medical resource gap drives online consults from disadvantaged to advantaged regions.Geography and culture constrain online medical consultation.Geography and culture also have moderating effects.The O2O nature of online consultation is a reason for the effect of geography.Online mechanisms mitigate the constraining effects of geography and culture. Online medical consultation platforms enable patients to seek health advice […]
Communicating male sexual dysfunction: The medicalization and psychologization of sexual experiences in Chinese online medical consultations
Online medical consultations (OMCs) enable adult men to openly discuss sexual dysfunction.Theme-Oriented Discourse Analysis is adopted to analyze OMCs about sexual dysfunction.Advice-seekers medicalize their sexual experiences to seek medical intervention.Doctors medicalize and psychologize advice-seekers’ sexual experiences.Both doctors and advice-seekers reproduce essentialist hetero-coital views of sexuality. Previous research shows that men who experience erectile or sexual […]

When my neighborhood woke up: Knitting collective action in disadvantaged areas amid the 2019 Chilean uprising. 15 April 2024
October 2019 saw the birth of the largest wave of demonstrations to hit Chile in the last 50 years. Protesters, the length of the country, soon joined in, voicing a broad range of demands and driving what has been described as a true “awakening” at the local level. This local dimension of the protests—that is, […]
Clarification notice to “The geography of military occupation and its effect on Palestinian community cohesion, norms, and resistance motivation” by Penić et al. (2023). 15 April 2024
Reports a clarification to "The Geography of Military Occupation and its Effect on Palestinian Community Cohesion, Norms, and Resistance Motivation" by Sandra Penić, Johanna Ray Vollhardt, Karsten Donnay, Mai Albzour and Ravi Bhavnani (Peace and Conflict: Journal of Peace Psychology, Advanced Online Publication, Jun 22, 2023, np). The authors wish to clarify the relationship between […]
School as a contested territory for citizenship: An ethnographic study of illegal occupation and protest processes at a popular vocational education school in the chilean october. 15 April 2024
The sociopolitical crisis that flared up in Chile starting in October 2019 laid bare tensions in how different social groups understand citizenship and political mobilization. These tensions evinced clear generational differences coupled with the emergence of new forms of understanding and doing politics among youth. This article presents the results of an ethnographic study conducted […]

Concretization as a possible mechanism of nightmare proneness: Some theoretical considerations and empirical findings. 28 March 2024
Nightmare proneness, a disposition to experience frequent nightmares, has been found to predict nightmares independent of neuroticism, psychological distress, and trauma symptoms. One theorized mechanism of nightmare proneness is concretization, a hypothetical defensive style in which vague and unpleasant inner states are made more tangible. The possible role of concretization in nightmare proneness and nightmares […]
Nightmare types and suicide. 28 March 2024
Previous research has robustly documented the relationship between sleep and suicide, where many aspects of poor sleep quality, sleep disturbances, and sleep disorders have been found to predict suicide. Research has also linked nightmares to suicide. It is not known, however, if nightmare types (idiopathic, trauma-related, and complex nightmares [nightmares with comorbid sleep and breathing […]
Veteran treatment completers’ and facilitators’ perceptions of cognitive behavioral therapy for insomnia and imagery rehearsal therapy for posttraumatic sleep disturbances. 13 November 2023
Cognitive behavioral therapy for insomnia (CBT-I) and imagery rehearsal therapy are recommended cognitive-behavioral treatments. However, little is known about the acceptability of the treatments for veterans with posttraumatic sleep disturbances. This study was conducted after a pilot randomized controlled trial that compared CBT-I with CBT-I combined with imagery rehearsal therapy (IRT) in a sample of […]

Hypertension After Kidney Donation; Statins in Old and Very Old People 1 June 2024
(MedPage Today) -- TTHealthWatch is a weekly podcast from Texas Tech. In it, Elizabeth Tracey, director of electronic media for Johns Hopkins Medicine in Baltimore, and Rick Lange, MD, president of the Texas Tech University Health Sciences Center...
FDA Staff Questions Safety of MDMA Treatment for PTSD 31 May 2024
(MedPage Today) -- FDA staff raised concerns about the available safety data and limitations in the study design for midomafetamine (MDMA) to treat post-traumatic stress disorder (PTSD) in briefing documents released ahead of an FDA Psychopharmacologic...
10 Psychiatrists Taking Over Social Media 30 May 2024
(MedPage Today) -- Mental health awareness month is coming to a close, but that doesn't mean psychiatrists are slowing down. The following 10 psychiatrists are outspoken mental health advocates and prominent ambassadors of their field. Check out...

What happens at night between 2 AM and 3 AM, when we are not sleeping 2 June 2024
Journal of Clinical Psychiatry published a study titled "The risk of suicide and homicide peaks at night: results from the national violent death ...
Some P.E.I. patients waiting many months for psychiatric services - CBC 2 June 2024
psychiatrist Dr. Javier Salabarria says some people may have to wait up to nine months to get psychiatric care. For more urgent cases, the wait ...
Health Equity and Access Weekly Roundup: June 1, 2024 2 June 2024
World Psychiatry. 2022;21(2): 248–271. doi:10.1002/wps.20994; Kadakia A, Catillon M, Fan Q, et al. The economic burden of schizophrenia in the ...

Gaza: Rafah camp attack heightens focus on dwindling health resources 28 May 2024
UN agencies on Tuesday reiterated their call for an urgent ceasefire and humanitarian access in Gaza following Israeli air strikes on Sunday that hit a camp for displaced Palestinians in Rafah, killing 45 people, according to the Hamas-run Ministry of Health.
COVID-19 eliminated a decade of progress in global level of life expectancy 24 May 2024
Data crunched by the UN World Health Organization (WHO) has revealed that the COVID-19 emergency reversed more than a decade of gains in life expectancy, reinforcing the need for countries to agree on a global pandemic treaty to protect future generations.
WHO report reveals major health disparities between European teens 23 May 2024
A report published on Thursday from the World Health Organization’s (WHO) European region has revealed alarming health disparities in young people, especially those from less affluent families, representing a “vicious cycle of disadvantage”.

#EndTB Webinar: WHO Guidance on conducting reviews of tuberculosis programmes 5 June 2024
The World Health Organization (WHO) is organising a global webinar on its newly-released guidance on conducting reviews of tuberculosis (TB) programmes and undertaking TB epidemiological reviews and assessments of TB surveillance and vital registration systems.The webinar aims to highlight the importance of bolstering review mechanisms, underscoring the urgency and importance of effective monitoring and evaluation strategies in the global […]
who.int
Fact sheets 1 June 2024
who.int
Events 1 June 2024
who.int

Awards for outstanding contributions to public health to be presented at Seventy-seventh World ... 30 May 2024
30 May 2024, Geneva, Switzerland/Cairo, Egypt – Eight awards are to be presented at the Seventy-seventh World Health Assembly to people and institutions from around the world for their outstanding contributions to public health in their countries and globally. Four of the awardees are from the Eastern Mediterranean Region. A special awards ceremony will take […]
Engaging journalists on promoting IPC and hand hygiene to save lives 29 May 2024
29 May 2024 – World Hand Hygiene Day (WHHD) has been marked for 16 years to advocate for hand hygiene as an evidence-based, practical approach to infection prevention and control (IPC) in health care settings. This helps limit the risk of epidemics and pandemics and control the spread of antimicrobial resistance (AMR). Countries the world […]
High-level panel discussion on health in Eastern Mediterranean Region explores ways to move ... 28 May 2024
28 May 2024, Geneva, Switzerland – A partnership event to highlight health challenges and opportunities and the WHO journey in the Eastern Mediterranean Region was held in Geneva on 25 May, ahead of the Seventy-seventh World Health Assembly. Hosted by the WHO Regional Director for the Eastern Mediterranean Dr Hanan Balkhy and fellow senior officials, […]

Systems Biology in ELIXIR: modelling in the spotlight [version 2; peer review: 1 approved, 2 approved with reservations] 31 May 2024
In this white paper, we describe the founding of a new ELIXIR Community - the Systems Biology Community - and its proposed future contributions to both ELIXIR and the broader community of systems biologists in Europe and worldwide. The Community believes that the infrastructure aspects of systems biology - databases, (modelling) tools and standards development, […]
Vitor Martins dos Santos
Effect of blood flow restriction training on pressure pain threshold and hand function among adults with persistent neck pain: A study protocol for a randomized controlled trial [version 2; peer review: 2 approved with reservations, 1 not approved] 31 May 2024
Background Persistent neck pain is a prevalent musculoskeletal condition that affects the quality of life and functional abilities of individuals. Blood Flow Restriction Training (BFRT) is a novel therapeutic approach that involves restricting blood flow to exercising muscles to enhance strength and function. However, limited research has been conducted on the effects of BFRT on […]
Mohammad Sidiq
Assessment of anticancer drug utilization pattern and patients’ survival—A single center experience from Saudi Arabia [version 1; peer review: awaiting peer review] 31 May 2024
Background In recent years, various advancements in anticancer therapy have led to the development of multiple regimens and protocols. This study endeavors to provide an extensive evaluation of anticancer therapy prescription patterns in correlation with patient outcomes. Methods From June 2014 to April 2022, we included adult cancer patients who received anticancer therapy in our […]
Ahmed Badheeb

Welcoming the New Chair and Vice-Chair of GLEAB 16 May 2024
We are delighted to welcome a brand new Chair and Vice Chair of the GLEAB.
galenos.org.uk
In Memory Of Lea Milligan 30 April 2024
Lea Milligan, CEO of MQ Mental Health Research and a founding member of the GALENOS leadership team passed away unexpectedly on the 15th of April following a sudden illness.
galenos.org.uk
What Are Ontologies and What Can They Be Used For? 14 April 2024
Janna Hastings talks to the Human Behaviour-Change Project about ontologies.
galenos.org.uk

Medicines eligible for Northern Ireland MHRA Authorised Route 31 May 2024
Sets out medicines that can be moved to Northern Ireland to meet patient need.
HM Government
Health and social care statistical outputs 29 May 2024
We are seeking views on health and social care statistical outputs published by DHSC (including OHID), NHSBSA, UKHSA, ONS and NHS England.
HM Government
New restrictions on puberty blockers 28 May 2024
New regulations restrict the prescribing and supply of puberty-suppressing hormones to children and young people under 18.
HM Government

Artificial Intelligence (AI): The Future of Data 20 May 2024
With the public release of large language models like Chat GPT putting Artificial Intelligence (AI) firmly on our radar, the...
stevemilne
Measuring wellbeing and going ‘Beyond GDP’ 9 May 2024
A new ONS publication out today, aims to give an holistic view on how society is doing, beyond purely economic measures. Here, Tim Vizard explores what we have done so far on Beyond GDP and outlines our next steps on this important work.
samcollin
Understanding the new income statistics for local areas: Different measures for better insights 30 April 2024
The ONS has been busy producing faster, more detailed statistics using new data sources. Providing clearer insights at the local level is an important aspect of this work. Ainslie Woods explains how our local income statistics compare and why they offer a complementary picture of local areas.
croydl

Raising the cyber resilience of software 'at scale' 31 May 2024
New ‘Code of Practice for Software Vendors’ will ensure that security is fundamental to developing and distributing products and services.
Offline backups in an online world 30 May 2024
How to protect your backups that are stored in the public cloud.
Scanning the internet for fun and profit 29 May 2024
Ian Levy explains how the NCSC's new internet scanning capability will help us understand the UK's vulnerability to cyber attack.

When I use a word . . . The languages of medicines—trade names, proprietary names, or brand-names 31 May 2024
Naming medicinesAs I have previously outlined,1 a medicine can have up to four types of names, distinguishing what a medicine or its name is from what the medicine or its name is called:● name 1—what the medicine is, as indicated by its full chemical name;● name 2—what the medicine’s name is, i.e. its generic name, […]
Jeffrey K Aronson
Gaza: Just one working hospital remains in Rafah, as healthcare worker death toll reaches 500 31 May 2024
Civilians in Rafah, in southern Gaza, are “once again in search of safety that doesn’t exist,” as Israeli airstrikes destroy camps sheltering displaced people and humanitarian facilities are “forced to close one after another,” the United Nations and World Health Organization have said.12Just one hospital, Emirati Maternity Hospital in Tal al-Sultan, remains functioning, albeit partly, […]
Elisabeth Mahase
Bird flu: US confirms first case with respiratory symptoms 31 May 2024
The US has recorded the first person with H5N1 flu to have respiratory symptoms, in what is thought to be the third human case in an ongoing outbreak among dairy farms. All previous confirmed cases of the infection in people had symptoms of conjunctivitis but no respiratory problems.“The patient reported upper respiratory tract symptoms, including […]
Mun-Keat Looi

'Outstanding' 5 Year PFS With Lorlatinib in ALK+ NSCLC 1 June 2024
Five-year follow-up data from the landmark CROWN trial shows significant progression-free survival in ALK+ NCSLC, but some experts question the use of crizotinib as the comparator drug. Medscape Medical News
AI Patient Navigator Can Boost Colonoscopy Adherence 1 June 2024
A virtual patient navigator improved colonoscopy uptake among a diverse and underserved population of English- and Spanish-speaking patients who had previously missed or avoided the procedure. Medscape Medical News
Defibrillation Lead Exceeds Expectations in Clinical Trial 31 May 2024
The small-diameter OmniaSecure defibrillation lead demonstrated implant success and accuracy in placement location. Medscape Medical News

Federal Experts Talk Bird Flu ‘What Ifs’ in WebMD Live Event 16 May 2024
WebMD brought together experts from four federal agencies to talk prevention, monitoring, and what the “what ifs” of bird flu might look like.
What’s Next in Health Care for Older Adults: Questions and Answers With John Whyte, MD 16 May 2024
As WebMD’s chief medical officer, John Whyte, MD, is in a unique position to see both the current state of medical care for America’s older adults and the way things are trending for the future. We asked him to share his insight on a few topics, along with a bit of advice.
Get the Care You Need in a COVID-19 World 16 May 2024
What to expect at the doctor’s office, hospitals, and long-term care facilities, the future of telemedicine, and how to get the best care during COVID-19.

Hassan Yahya: Family respond to inquest conclusion following fatal police shooting 31 May 2024
31 May 2024
Inquest
Hassan Yahya: Family respond to inquest conclusion following fatal police shooting 31 May 2024
31 May 2024 HM Senior Coroner for Westminster, Professor Fiona Wilcox Westminster Coroner’s Court 13 May – 31 May 2024 An inquest Jury has today concluded that Hassan Yahya, a 30 year old Black man, was lawfully killed when he was shot by a City of London police officer in central London on the night […]
inquest.org.uk
Linda's story: transforming grief into power through photography 31 May 2024
Bereaved mother and campaigner, Linda Allan, on the power of the SoulsINQUEST photography exhibition to transform grief following the loss of her daughter.
Inquest

Integrating mitoepigenetics into research in mood disorders: a state-of-the-art review

Evidence

Latest: Psychiatryai.com #RAISR4D

Cool Evidence: Engaging Young People and Students in Real-World Evidence ☀️

Real-Time Evidence Search [Psychiatry]

AI Research [Andisearch.com]

Integrating mitoepigenetics into research in mood disorders: a state-of-the-art review

🌐 90 Days

VR Related Evidence Matrix

Evidence Blueprint

Integrating mitoepigenetics into research in mood disorders: a state-of-the-art review

☊ AI-Driven Related Evidence Nodes

(recent articles with at least 5 words in title)

More Evidence

Integrating mitoepigenetics into research in mood disorders: a state-of-the-art review

🌐 365 Days

VR Related Evidence Matrix

Obesity, psychological well-being related measures, and risk of seven non-communicable diseases: evidence from longitudinal studies of UK and US older adults

Impact of gender violence on girls and adolescents

Global Mental Health and Immigrant Families

Impact of gender violence on girls and adolescents

Global Mental Health and Immigrant Families

Re-Imagining Child Welfare to Support Children and Families

Re-Imagining Child Welfare to Support Children and Families

Thematic Synthesis of the Experiences of Intimate Partner Violence Among Mothers Who Use Substances

Restrictive visa policies harm global scientific exchanges

Top Category

News

Medicine

Psychiatry

Evidence

Latest: Psychiatryai.com #RAISR4D

Cool Evidence: Engaging Young People and Students in Real-World Evidence ☀️

Real-Time Evidence Search [Psychiatry]

AI Research [Andisearch.com]

🌐 90 Days

VR Related Evidence Matrix

Evidence Blueprint

☊ AI-Driven Related Evidence Nodes

(recent articles with at least 5 words in title)

More Evidence

🌐 365 Days

VR Related Evidence Matrix

New Evidence

Recent Post

Top Category