AI Summary
- Clinical threshold denotes the point at which expected therapeutic benefit outweighs potential harms, guiding when psychiatric interventions should be initiated.
- Determination requires integration of symptom severity, prognosis, evidence quality, comorbidity, and individual preferences to balance benefits, harms, and resource implications.
- Policy and clinical practice should transparently define thresholds, monitor outcomes, and adjust thresholds to minimise overtreatment while ensuring timely care.
JAMA Psychiatry. 2026 Jul 1. doi: 10.1001/jamapsychiatry.2026.1759. Online ahead of print.
NO ABSTRACT
PMID:42384391 | DOI:10.1001/jamapsychiatry.2026.1759
Share Evidence Blueprint

Search Google Scholar
Save as PDF

