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Cool Evidence: Engaging Young People and Students in Real-World Evidence
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Real-Time Evidence Search [Psychiatry]
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AI Research
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AI finds old drugs that can treat new COVID variants
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🌐 90 Days
AI Virtual Reality Related Evidence Matrix
More Americans Say Climate Change Is Having an Impact on Mental Health Now Than in 2022, APA Survey Finds Adopting net zero technologies will save UK economy billions, finds Smith School analysis Repurposing General Anesthetic Drugs to Treat Depression: A New Frontier for Anesthesiologists in Neuropsychiatric Care Gtie-Rt: A Comprehensive Graph Learning Model for Predicting Drugs Targeting Metabolic Pathways in Human The phenotypic and genotypic spectrum of individuals with mono- or biallelic ANK3 variants Prediction of the Need for Anticonvulsants in the Management of Orofacial Neuropathic Pain Using Machine Learning Schizophrenia interactome derived repurposable drugs and randomized control trials of two candidates Shorter life expectancy during COVID-19 for India’s marginalised A Talking Cure for Psychosis: Cognitive-behavioral therapy helps to treat symptoms for which drugs are ineffective Immunogenicity of the Monovalent Omicron XBB.1.5-Adapted BNT162b2 COVID-19 Vaccine in People Living with HIV (PLWH) Investigating Substance Use as a Coping Strategy Among Adolescent Psychiatric Inpatients: A Comparative Analysis Before and During the COVID-19 Pandemic Haploinsufficiency underlies the neurodevelopmental consequences of SLC6A1 variants FDA-Approved Drugs to Treat Bipolar I and II Disorders Biophysics Seminar 4 TT7 Increases in benzodiazepine prescribing for postpartum anxiety during COVID-19 De novo monoallelic Reelin missense variants act in a dominant-negative manner causing neuronal migration disorders Attenuated responses to attention-modulating drugs in the neuroligin-3(R451C) mouse model of autism New drug treatments for schizophrenia: a review of approaches to target circuit dysfunction Unveiling promising drug targets for autism spectrum disorder: insights from genetics, transcriptomics, and proteomics Evidence for Therapeutic Drug Monitoring of Atypical Antipsychotics Clinical Pipelines for Alzheimer's Disease Psychosis and Agitation Primary and Secondary Callous-Unemotional Childhood Variants in a Korean Community Sample Dementia incidence varied by anticancer drugs and molecular targeted therapy in a population-based cohort study Immune signature in vaccinated versus non-vaccinated aged people with COVID-19 pneumonia The contribution of silencer variants to human diseases The contribution of silencer variants to human diseases Whole-genome sequencing identifies novel genes for autism in Chinese trios Whole genome sequencing study of identical twins discordant for psychosis Clinical characteristics and pathophysiological properties of newly discovered LRRK2 variants associated with Parkinson's disease Heterozygosity for loss-of-function variants in LZTR1 is associated with isolated multiple café-au-lait macules Mutations in the tail and rod domains of the neurofilament heavy-chain gene increase the risk of ALS Mutations in the tail and rod domains of the neurofilament heavy-chain gene increase the risk of ALS Whole-exome sequencing of individuals from an isolated population under extreme conditions implicates rare risk variants of schizophrenia Secondary ACMG and non-ACMG genetic findings in a multiethnic cohort of 16,713 pediatric participants Effects of a New Group of Antidiabetic Drugs in Metabolic Diseases Therapeutic Potential of Psychedelic Drugs: Navigating High Hopes, Strong Claims, Weak Evidence, and Big Money De novo variants in immune regulatory genes in Down syndrome regression disorder De novo variants in the RNU4-2 snRNA cause a frequent neurodevelopmental syndrome Biallelic NDC1 variants that interfere with ALADIN binding are associated with neuropathy and Triple-A-like syndrome Some aspects of non-medical use of narcotic substances The Association Between Functional Variants in Long Non-coding RNAs and the Risk of Autism Spectrum Disorder Was Not Mediated by Gut Microbiota De novo and inherited monoallelic variants in TUBA4A cause ataxia and spasticity Whole exome sequencing analysis identifies genes for alcohol consumption Whole exome sequencing analysis identifies genes for alcohol consumption Drosophila learning and memory centers and the actions of drugs of abuse High Clinical and Genetic Similarity Between Chronic Pancreatitis Associated With Light-to-Moderate Alcohol Consumption and Classical Alcoholic Chronic Pancreatitis Clinical Utility of Protein Language Models in Resolution of Variants of Uncertain Significance in KCNQ1, KCNH2, and SCN5A Compared With Patch-Clamp Functional Characterization Rare and common variants associated with alcohol consumption identify a conserved molecular network A Systematic Review on Ketamine and Esketamine for Treatment-Resistant Depression and Suicidality in Adolescents: A New Hope? Finemap-MiXeR: A variational Bayesian approach for genetic finemapping Burden re-analysis of neurodevelopmental disorder cohorts for prioritization of candidate genes Encephalocraniocutaneous lipomatosis phenotype associated with mosaic biallelic pathogenic variants in the NF1 gene Encephalocraniocutaneous lipomatosis phenotype associated with mosaic biallelic pathogenic variants in the NF1 gene Study of the genetic association between selected 3q29 region genes and schizophrenia and autism spectrum disorder in the Japanese population Study of the genetic association between selected 3q29 region genes and schizophrenia and autism spectrum disorder in the Japanese population Stroke Risk After Emergency Department Treat-and-Release Visit for a Fall Journey from lab to clinic: Design, preclinical, and clinical development of systemic, targeted dendrimer-N-acetylcysteine (D-NAC) nanomedicines Potassium and calcium channels in different nerve cells act as therapeutic targets in neurological disorders Phytoactive drugs used in the treatment of Alzheimer's disease and dementia Impact of COVID-19 pandemic on prescription of psychotropic medications in the Italian paediatric population during 2020 Prevalence of drugs used for chronic conditions after diagnosis of thyroid cancer: A register-based cohort study Pediatric Pharmacology for the Primary Care Provider: Advances and Limitations Heterozygosity for neurodevelopmental disorder-associated TRIO variants yields distinct deficits in behavior, neuronal development, and synaptic transmission in mice Heterozygosity for neurodevelopmental disorder-associated TRIO variants yields distinct deficits in behavior, neuronal development, and synaptic transmission in mice
Evidence Blueprint
AI finds old drugs that can treat new COVID variants
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AI finds old drugs that can treat new COVID variants
🌐 365 Days
AI Virtual Reality Related Evidence Matrix
Mobilizing Whiteness: Race, Futurity and Globalization of Higher Education Designing combinational herbal drugs based on target space analysis More Americans Say Climate Change Is Having an Impact on Mental Health Now Than in 2022, APA Survey Finds Genetic Predictors of Comorbid Course of COVID-19 and MAFLD: A Comprehensive Analysis Fluoxetine and Sertraline Potently Neutralize the Replication of Distinct SARS-CoV-2 Variants Analysis of rare Parkinson's disease variants in millions of people Excellent hepatitis C virus cure rates despite increasing complexity of people who use drugs: Integrated-Test-stage Treat study final outcomes Increased Pill Burden and Adverse Effects of Psychotropics Correlated with Poor Quality of Life and Medication Nonadherence: A Cross-sectional Drug Utilization Study at a Tertiary Care Hospital in Delhi during COVID-19 Pandemic Phytochemicals against Osteoarthritis by Inhibiting Apoptosis Adopting net zero technologies will save UK economy billions, finds Smith School analysis Pharmacological fingerprint of antipsychotic drugs at the serotonin 5-HT2A receptor Repurposing General Anesthetic Drugs to Treat Depression: A New Frontier for Anesthesiologists in Neuropsychiatric Care Gtie-Rt: A Comprehensive Graph Learning Model for Predicting Drugs Targeting Metabolic Pathways in Human The trend of poisonings before and after the COVID-19 pandemic The neurobiology of SARS-CoV-2 infection The OSR9 Regimen: A New Augmentation Strategy for Osteosarcoma Treatment Using Nine Older Drugs from General Medicine to Inhibit Growth Drive The phenotypic and genotypic spectrum of individuals with mono- or biallelic ANK3 variants Treat Obesity to Treat Type 2 Diabetes Mellitus Prediction of the Need for Anticonvulsants in the Management of Orofacial Neuropathic Pain Using Machine Learning Narrative Review: Pathogenesis of the Inflammatory Response and Intestinal Flora in Depression Frequencies of CYP2C19 and CYP2D6 gene variants in a German inpatient sample with mood and anxiety disorders The pleiotropic approach to coronavirus disease-19 pathogenesis: The impact of liver diseases associated host genetic variants Schizophrenia interactome derived repurposable drugs and randomized control trials of two candidates Microgel Encapsulated Nanoparticles for Intra-articular Disulfiram Delivery to Treat Osteoarthritis Potassium channel-related epilepsy: Pathogenesis and clinical features Shorter life expectancy during COVID-19 for India’s marginalised Further characterisation of ARX-related disorders in females due to inherited or de novo variants Total network controllability analysis discovers explainable drugs for Covid-19 treatment A Talking Cure for Psychosis: Cognitive-behavioral therapy helps to treat symptoms for which drugs are ineffective Differential responses of disease-related GRIN variants located in pore-forming M2 domain of N-methyl-D-aspartate receptor to FDA-approved inhibitors The effect of suicide severity and patient's age on mental health professionals' willingness to treat: The moderating effect of ageism Immunogenicity of the Monovalent Omicron XBB.1.5-Adapted BNT162b2 COVID-19 Vaccine in People Living with HIV (PLWH) In vitro and in silico investigation of FDA-approved drugs to be repurposed against Alzheimer's disease Investigating Substance Use as a Coping Strategy Among Adolescent Psychiatric Inpatients: A Comparative Analysis Before and During the COVID-19 Pandemic Machine Learning to Identify Critical Biomarker Profiles in New SARS-CoV-2 Variants PharmVar Tutorial on CYP2D6 Structural Variation Testing and Recommendations on Reporting Haploinsufficiency underlies the neurodevelopmental consequences of SLC6A1 variants Advanced variant classification framework reduces the false positive rate of predicted loss-of-function variants in population sequencing data FDA-Approved Drugs to Treat Bipolar I and II Disorders Rare germline variants in POLE and POLD1 encoding the catalytic subunits of DNA polymerases ε and δ in glioma families FDA-Approved Drugs to Treat Dementia The first case of intellectual disability caused by novel compound heterozygosity for NUDT2 variants The melatonin receptor genes are linked and associated with the risk of polycystic ovary syndrome Biophysics Seminar 4 TT7 Patients hospitalized with active tuberculosis and Covid-19 coinfection: A matched case-control from the Brazilian Covid-19 Registry Large-Scale Screening: Phenotypic and Mutational Spectrum in Isolated and Combined Dystonia Genes A Narrative Review on Pharmacogenomics in Psychiatry: Scientific Definitions, Principles, and Practical Resources Increases in benzodiazepine prescribing for postpartum anxiety during COVID-19 Impact of three variants of prolonged exposure therapy on comorbid diagnoses in patients with childhood abuse-related PTSD Mode and site of action of therapies targeting CGRP signaling Transport mechanism and pharmacology of the human GlyT1 Protocol for a living evidence synthesis on variants of concern and COVID-19 vaccine effectiveness COVID-19 vaccines found to be effective in reducing long COVID symptoms Comparison of three bioinformatics tools in the detection of ASD candidate variants from whole exome sequencing data De novo monoallelic Reelin missense variants act in a dominant-negative manner causing neuronal migration disorders Attenuated responses to attention-modulating drugs in the neuroligin-3(R451C) mouse model of autism Clinical Variants Paired with Phenotype: A Rich Resource for Brain Gene Curation New drug treatments for schizophrenia: a review of approaches to target circuit dysfunction Unveiling promising drug targets for autism spectrum disorder: insights from genetics, transcriptomics, and proteomics A Two-Phased Telehealth Model to Treat Post-Traumatic Stress Disorder in a Health Care Worker due to the COVID-19 Pandemic: A Case Report Evidence for Therapeutic Drug Monitoring of Atypical Antipsychotics Prevalence of pathogenic variants and digenic disease in patients diagnosed with normosmic hypogonadotropic hypogonadism/Kallmann Syndrome Adverse childhood experiences, individual-level risk and protective factors, and recent drug use in a community sample of Nigerian women Genetic Analysis of Obstructive Sleep Apnea and Its Relationship with Severe COVID-19