CIMT 2024: Report on the 21st Annual Meeting of the Association for Cancer Immunotherapy

24 July 2024

Evidence

Hum Vaccin Immunother. 2024 Dec 31;20(1):2381925. doi: 10.1080/21645515.2024.2381925. Epub 2024 Jul 23.

ABSTRACT

The 21^st Association for Cancer Immunotherapy (CIMT) Annual Meeting took place from May 15^th to May 17^th in Mainz, Germany, and was attended by a total of 855 academic and clinical professionals hailing from 33 different countries. The conference served as a platform for these experts to convene and discuss the latest breakthroughs in cancer immunology and immunotherapy research. Dedicated sessions covering advancements in artificial intelligence tools for cancer immunotherapy research, as well as the landscape of cancer care and cancer immunotherapy trials on the African continent, prompted lively and informative discussions among the attendees. This report aims to provide an overview of the most noteworthy highlights and key takeaways from CIMT2024.

PMID:39043196 | DOI:10.1080/21645515.2024.2381925

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Stephen Allison

Evaluating counselling skills of community health workers for pregnant adolescents in Limpopo province 30 July 2024
Background: Adolescent pregnancy carries significant global ramifications. Community health workers (CHWs) play a role in empowering adolescents through counselling skills, thereby promoting informed decision-making for better outcomes.Aim: The study aims to evaluate the counselling skills of CHWs in their efforts to support pregnant adolescents (PA) in Limpopo province.Setting: The research was carried out with CHWs in the Mopani […]
Rakgadi G. Malapela
Cannabis use among hospitalised adolescents before and after decriminalisation in South Africa 26 July 2024
Background: Cannabis is the most widely used substance worldwide, and its use is much higher among adolescents. However, adolescents are at higher risk of negative sequelae secondary to this use, including the possible development of mental disorders. On 31 March 2017, the South African High Court ruled that cannabis use by an adult in a private […]
Michelle C. Swartz
The prevalence of anxiety in pregnant women at Chris Hani Baragwanath Academic Hospital 23 July 2024
Background: Non-psychotic mental disorders are common during the perinatal period. In South Africa, there are few studies on antenatal anxiety and these results vary. Antenatal anxiety does not only add to the burden of perinatal co-morbidity but has subsequent immediate and long-term effects on the mother, birth outcomes and her offspring.Aim: The aim of this study was […]
Lisha Narayan

A systematic review and meta-analysis on the transcriptomic signatures in alcohol use disorder 6 September 2024
Molecular Psychiatry, Published online: 06 September 2024; doi:10.1038/s41380-024-02719-xA systematic review and meta-analysis on the transcriptomic signatures in alcohol use disorder
Marion M. Friske
Impaired macroautophagy confers substantial risk for intellectual disability in children with autism spectrum disorders 6 September 2024
Molecular Psychiatry, Published online: 06 September 2024; doi:10.1038/s41380-024-02741-zImpaired macroautophagy confers substantial risk for intellectual disability in children with autism spectrum disorders
Ahrom Ham
MiR-186-5p inhibition restores synaptic transmission and neuronal network activity in a model of chronic stress 5 September 2024
Molecular Psychiatry, Published online: 05 September 2024; doi:10.1038/s41380-024-02715-1MiR-186-5p inhibition restores synaptic transmission and neuronal network activity in a model of chronic stress
Beatriz Rodrigues

Plaudits for logits in sensory neuroscience
A workhorse tool of economic decision-making has long sought to get inside people’s heads through careful examination of their choices. In this issue of , Carandini flips the script, showing how it can model how the brain makes sensory choices.A workhorse tool of economic decision-making has long sought to get inside people’s heads through careful […]
Impacts beyond the brain: Unraveling molecular mechanisms linking psychiatric, metabolic, and inflammatory conditions
By establishing semaphorin 6D expression in the amygdala as a central coordinator of brain, metabolic, and immunologic function, the publication by Nakanishi et al. provides new insight to how primary brain deficiency impacts physiological systems beyond the brain.By establishing semaphorin 6D expression in the amygdala as a central coordinator of brain, metabolic, and immunologic function, the […]
Keep calm and carry H3K27me1 off
In this issue of , Torres-Berrío et al. show that stress-susceptible mice exhibit elevated H3K27me1 levels in nucleus accumbens neurons due to the action of the SUZ12 VEFS domain, strengthening the link between specific epigenetic changes and long-lasting stress-induced social, emotional, and cognitive alterations.In this issue of , Torres-Berrío et al. show that stress-susceptible mice exhibit elevated […]

The role of workplace managers in protecting and promoting employee mental health 2 September 2024
Nature Mental Health, Published online: 02 September 2024; doi:10.1038/s44220-024-00308-zThe role of workplace managers in protecting and promoting employee mental health
Leslie B. Hammer
Neocortical serotonin 2A receptor binding, neuroticism and risk of developing depression in healthy individuals 26 August 2024
Nature Mental Health, Published online: 26 August 2024; doi:10.1038/s44220-024-00299-xIn this study, the authors used molecular brain imaging and measures of neuroticism to identify that high 5-HT2AR binding and higher levels of neuroticism predicted an increased risk of developing depression up to 19 years after assessment.
Anjali Sankar
Mapping brain and body connections 26 August 2024
Nature Mental Health, Published online: 26 August 2024; doi:10.1038/s44220-024-00304-3In this Q&A, we speak to Andrew Zalesky, professor at the University of Melbourne, a co-leader of the Systems Lab and awardee of the prestigious Rebecca L. Cooper Fellowship that provides US$1.35 million over 5 years to study brain networks in health and disease and develop high-tech […]
Natalia Gass

Orphan receptor-GPR52 inverse agonist efficacy in ameliorating chronic stress-related deficits in reward motivation and phasic accumbal dopamine activity in mice 7 September 2024
Translational Psychiatry, Published online: 07 September 2024; doi:10.1038/s41398-024-03081-wOrphan receptor-GPR52 inverse agonist efficacy in ameliorating chronic stress-related deficits in reward motivation and phasic accumbal dopamine activity in mice
Chenfeng Zhang
A systematic review of deep brain stimulation for substance use disorders 6 September 2024
Translational Psychiatry, Published online: 06 September 2024; doi:10.1038/s41398-024-03060-1A systematic review of deep brain stimulation for substance use disorders
David Zammit Dimech
Next-generation precision medicine for suicidality prevention 6 September 2024
Translational Psychiatry, Published online: 06 September 2024; doi:10.1038/s41398-024-03071-yNext-generation precision medicine for suicidality prevention
R. Bhagar

The relationship between corticospinal excitability and structural integrity in stroke patients 6 September 2024
BackgroundEvaluation of the structural integrity and functional excitability of the corticospinal tract (CST) is likely to be important in predicting motor recovery after stroke. Previous reports are inconsistent regarding a possible link between CST structure and CST function in this setting. This study aims to investigate the structure-function relationship of the CST at the acute […]
Daghsen, L., Checkouri, T., Wittwer, A., Valabregue, R., Galanaud, D., Lejeune, F.-X., Doulazmi, M., Lamy, J.-C., Pouget, P., Roze, E., Rosso, C.
Intermediate HTT CAG repeats worsen disease severity in amyotrophic lateral sclerosis 6 September 2024
IntroductionRecent research has indicated a connection between amyotrophic lateral sclerosis (ALS) and Huntington’s disease (HD), an inherited neurological condition caused by a trinucleotide CAG repeat expansion within exon 1 of the Huntingtin gene (HTT; MIM:613004).1 The same pathogenic CAG repeat expansions (40 or more CAG repeats) observed in patients with HD have been identified in […]
Grassano, M., Canosa, A., DAlfonso, S., Corrado, L., Brodini, G., Koumantakis, E., Cugnasco, P., Manera, U., Vasta, R., Palumbo, F., Mazzini, L., Gallone, S., Moglia, C., Dewan, R., Chia, R., Ding, J., Dalgard, C., Gibbs, R. J., Scholz, S., Calvo, A., Traynor, B., Chio, A.
Prognosis prediction and immunotherapy optimisation for cryptogenic new-onset refractory status epilepticus 5 September 2024
BackgroundCryptogenic new-onset refractory status epilepticus (cNORSE) currently lacks comprehensive knowledge regarding its clinical dynamics, prognostic factors and treatment guidance. Here we present the longitudinal clinical profiles, predictive factors for outcomes and the optimal duration of immunotherapy in patients with cNORSE.MethodsThis retrospective secondary endpoint analysis investigated patients with cNORSE identified from a prospective autoimmune encephalitis cohort […]
Jang, Y., Ahn, S. H., Park, K.-I., Jang, B.-S., Lee, H. S., Bae, J.-H., Lee, Y., Sunwoo, J.-S., Jun, J.-S., Kim, K. T., Mon, S. Y., You, J. H., Kim, T.-J., Shin, H., Han, D., Cho, Y. W., Dubey, D., Chu, K., Lee, S. K., Lee, S.-T.

Mendelian randomization: causal inference leveraging genetic data 19 April 2024
Mendelian randomization (MR) leverages genetic information to examine the causal relationship between phenotypes allowing for the presence of unmeasured confounders. MR has been widely applied to unresolved questions in epidemiology, making use of summary statistics from genome-wide association studies on an increasing number of human traits. However, an understanding of essential concepts is necessary for […]
Chen, Lane G.
Interventions targeting social determinants of mental disorders and the Sustainable Development Goals: a systematic review of reviews 25 March 2024
Globally, mental disorders account for almost 20% of disease burden and there is growing evidence that mental disorders are socially determined. Tackling the United Nations Sustainable Development Goals (UN SDGs), which address social determinants of mental disorders, may be an effective way to reduce the global burden of mental disorders. We conducted a systematic review […]
Oswald, Tassia Kate
Do metacognitive therapies for schizophrenia-spectrum disorders work? A meta-analytic investigation 21 March 2024
Recent reviews and meta-analyses of metacognitive therapy for schizophrenia-spectrum disorder (SSD) have included uncontrolled studies, single-session interventions, and/or analyses limited to a single form of metacognitive therapy. We sought to evaluate the efficacy of metacognitive therapies more broadly based on controlled trials (CT) of sustained treatments. We conducted a pre-registered meta-analysis of controlled trials that […]
Melville, Grace

Childhood maltreatment and outcomes following electroconvulsive therapy in adults with depression 5 September 2024
Acta Psychiatrica Scandinavica, EarlyView.
Ana Jelovac, Christopher Mohan, Emma Whooley, Anna Igoe, Cathal McCaffrey, Declan M. McLoughlin
Association between exposure to atypical antipsychotics during pregnancy and risk of miscarriage 5 September 2024
Acta Psychiatrica Scandinavica, EarlyView.
Tomofumi Ishikawa, Takamasa Sakai, Noriyuki Iwama, Ryo Obara, Kei Morishita, Motohiko Adomi, Aoi Noda, Mami Ishikuro, Saya Kikuchi, Natsuko Kobayashi, Hiroaki Tomita, Masatoshi Saito, Hidekazu Nishigori, Shinichi Kuriyama, Nariyasu Mano, Taku Obara
Monoamine oxidase inhibitors: Seriously underused in the treatment of major depression 4 September 2024
Acta Psychiatrica Scandinavica, EarlyView.
Tom K. Birkenhager, Willemijn T. Heijnen

Idiosyncratic Reaction of Isotretinoin: A Review 6 September 2024
Dermatological Reviews, Volume 5, Issue 5, October 2024.
Kar Wai Alvin Lee, Lisa Kwin Wah Chan, Cheuk Hung Lee, Jovian Wan, Kyu‐Ho Yi
Pathways to personalized medicine—Embracing heterogeneity for progress in clinical therapeutics research in Alzheimer's disease 6 September 2024
Alzheimer's &Dementia, EarlyView.
Steven E. Arnold, Bradley T. Hyman, Rebecca A. Betensky, Hiroko H. Dodge
Key actors in neuropathophysiology: The role of γδ T cells 6 September 2024
European Journal of Immunology, EarlyView.
Deniz Bulgur, Raquel Macedo Moura, Julie C. Ribot

A role for Shugoshin in human cilia?
We have recently described a novel role for the conserved centromeric/kinetochore protein and cohesin protector, Shugoshin, in cilia of C. elegans. Worms are unusual in that the sole Shugoshin protein ( SGO-1 ) is dispensable for chromosome segregation but required for cilia function in fully differentiated sensory neurons. Depletion of sgo-1 leads to an array […]
sut-2 loss of function mutants protect against tau-driven shortened lifespan and hyperactive pharyngeal pumping in a C. elegans model of tau toxicity.
Expression of human tau in C. elegans neurons causes progressive, age-associated loss of motor coordination, selective neurodegeneration, and shortened lifespan. Loss of function (LOF) mutations in the conserved gene sut-2 protects against progressive motor uncoordination and neurodegeneration in models of tauopathy. To determine whether sut-2 LOF also protects against shortened lifespan of tau transgenic C. […]
Evidence Based Clinical Analytics Supporting the Genetic Addiction Risk Severity (GARS) Assessment to Early Identify Probands in Preaddiction.
No abstract supplied.

Evolving Perspectives on Wellness and Stress
Renewing the Teaching of Clinical Reasoning in Psychiatry: An Opportunity for Advancing Mental Health Training and Care
Assaults and Microaggressions Against Psychiatric Residents: Findings from a US Survey
Psychiatric physicians may experience higher rates of assault than those in other fields. For many reasons, residents may be especially vulnerable. This study updates rates of assaults among US psychiatry residents as well as the reporting rates and emotional effects of these incidents. Little data exists to examine rates of microaggressions against psychiatry residents.A cross-sectional […]

Enhancing Brain Health and Well-Being in Older Adults: Innovations in Lifestyle Interventions
This article will provide clinicians with guidance on helping older adult patients make lifestyle changes to enhance brain health and well-being.Evidence suggests that physical activity might be helpful in improving cognitive functioning. The data on the benefits of cognitive activity is inconsistent and not as robust. The MediDiet, DASH, and MIND diets have been associated […]
Management of MCI in the Outpatient Setting
We review current literature related to the clinical assessment of Mild Cognitive Impairment (MCI). We compile recommendations related to the evaluation of MCI and examine literature regarding the use of clinical biomarkers in this assessment, the role of non-pharmacologic therapy in the prevention of cognitive decline, and recent approval of anti-amyloid therapy in the treatment […]
Cross-Cultural Patient Counseling and Communication in the Integrative Medicine Setting: Respecting the Patient's Health Belief Model of Care
Communicating effectively with patients having a traditional, alternative or complementary medicine-related health-belief model is challenging in today’s cross-cultural society. This narrative review explores the integrative medicine setting of care, focusing on insights from the integrative oncology daily practice, while addressing the relevance to the mental health setting. The way in which healthcare providers can enhance […]

Editorial introductions
No abstract available
journals.lww.com
Sex and gender differences in cancer in individuals with severe mental disorders
Purpose of review Although cancer incidence is similar between individuals with severe mental disorders (SMD) and the general population (GP), survival rates are lower, particularly in those with schizophrenia. While the scientific and medical communities acknowledge sex differences in cancer mechanisms, including risk factors and cancer types, less is known about sex and gender disparities […]
Bajić, Žarko; Vuk-Pisk, Sandra; Filipčić, Igor; Šimunović Filipčić, Ivona
The role of human involvement and support in digital mental health interventions for people with schizophrenia spectrum disorders: a critical review
Purpose of review Schizophrenia spectrum disorders (SDD) are characterized by a complex array of psychosis symptoms, and typically require ongoing and long-term support, including pharmacological and nonpharmacological management. Digital mental health interventions (DMHIs) have been suggested as a novel therapeutic approach to enable low-cost, scalable improvements in quality of care for adults living with SSD. […]
Arnautovska, Urska; Milton, Alyssa; Trott, Mike; Soole, Rebecca; Siskind, Dan

Daily-life reactivity and emotion regulation in children with social anxiety disorder
Little is known about maintaining factors of child social anxiety disorder (SAD).High daily-life reactivity and use of suppression are specific to child SAD.Maladaptive emotion regulation predicts trait social anxiety one year later.Treatment should put more focus on reducing maladaptive emotion regulation. Prominent models of adult social anxiety disorder emphasize the role of hyperreactivity and emotion […]
Correlates of treatment-seeking in DSM-5 generalized anxiety disorder: Findings from the National Epidemiologic Survey on Alcohol and Related Conditions‐III
47 % of those with lifetime GAD received therapy or medication for GAD.PTSD, depression, and panic disorder were associated with treatment seeking.Fatigue, panic attacks, reassurance seeking, and interpersonal avoidance were also related. Generalized Anxiety Disorder (GAD) presents a significant personal and societal burden and is associated with chronic medical comorbidities and markedly lower quality of life. […]
Scaling up psychological interventions into the daily lives of patients with anxiety and related disorders

Behavioral characteristics of toddlers later identified with an autism diagnosis, ADHD symptoms, or combined autism and ADHD symptoms 3 September 2024
Journal of Child Psychology and Psychiatry, EarlyView.
Naomi O. Davis, Reginald Lerebours, Rachel E. Aiello, Kimberly L.H. Carpenter, Scott Compton, Lauren Franz, Scott H. Kollins, Maura Sabatos‐DeVito, Marina Spanos, Geraldine Dawson
Practitioner Review: Treatments for young people who self‐harm – challenges and recommendations for research and clinical practice 28 August 2024
Journal of Child Psychology and Psychiatry, EarlyView.
Katrina Witt, Anne Stewart, Keith Hawton
Editorial: Reciprocity between sleep and mood in early childhood – an under‐explored neural marker of depression risk 19 August 2024
Journal of Child Psychology and Psychiatry, Volume 65, Issue 9, Page 1133-1134, September 2024.
Caroline Hoyniak, Joan Luby

Psychotropic medication and hepatobiliary health: Ultrasound observations on patients with schizophrenia 5 September 2024
The International Journal of Psychiatry in Medicine, Ahead of Print. ObjectiveThis study sought to examine the association between antipsychotic drug use and hepatobiliary health based on serum markers and ultrasound observations on a sample of patients with schizophrenia compared to age and gender matched healthy controls.MethodsThe 120 patients with schizophrenia and 60 control subjects had […]
Linlin Yue
A case and intervention for older adult sexual mistreatment 30 August 2024
The International Journal of Psychiatry in Medicine, Ahead of Print. BackgroundThe sexual mistreatment of older adults is a significant public health issue; like other forms of sexual violence, it is more prevalent than officially reported. Survivors often hesitate to speak out due to feelings of embarrassment, fear, or potential cognitive impairments. Moreover, the concealment of […]
Renee J. Flores
Evaluation of postoperative delirium in geriatric patients given acetaminophen with and without melatonin: A retrospective cohort study 20 August 2024
The International Journal of Psychiatry in Medicine, Ahead of Print. ObjectivePostoperative delirium has many consequences and should be prevented when possible. Non-opioid pain treatments have known delirium prevention benefits, while melatonin has promising prevention data in non-surgical populations. The incidence of postoperative delirium was retrospectively compared in patients prescribed acetaminophen with and without melatonin following […]
Maria N. Muehrcke

Research landscape analysis on dual diagnosis of substance use and mental health disorders: key contributors, research hotspots, and emerging research topics 30 August 2024
Substance use disorders (SUDs) and mental health disorders (MHDs) are significant public health challenges with far-reaching consequences on individuals and society. Dual diagnosis, the coexistence of SUDs and...
Waleed M. Sweileh
Association between rTMS-induced changes in inflammatory markers and improvement in psychiatric diseases: a systematic review 27 August 2024
Repetitive transcranial magnetic stimulation (rTMS) has recently gained relevance in treating different psychiatric disorders. Limited evidence suggests that the beneficial effects of rTMS on psychopathology c...
Bruno Pedraz-Petrozzi, Shrabon Insan, Moritz Spangemacher, Jonathan Reinwald, Eva Kathrin Lamadé, Maria Gilles, Michael Deuschle and Alexander Sartorius
Maternal depression and early childhood development among children aged 24–59 months: the mediating effect of responsive caregiving 20 August 2024
This study examined whether maternal depression is related to Early Childhood Developmental (ECD) delay among children by quantifying the mediating contribution of responsive caregiving. We used data from 1235...
Siyu Zou, Xinye Zou, Ruolin Zhang, Kefan Xue, Angela Y. Xiao, Mo Zhou, Ziyuan Fu and Hong Zhou

Sexual Orientation Microaggression Rating Scale (SOMRS): Development and association with alliance ruptures. 8 August 2024
Sexual minority clients report experiencing frequent microaggressions during therapy, however, therapists may not recognize those microaggressions or may be reluctant to self-report them. The main aim of the present study was thus to develop an observational measure of in-session therapist-committed microaggressions related to the sexual orientation of sexual minority individuals (e.g., those who identify as […]
Should we feel the same? Mutual recognition and congruence between therapist and client regarding ruptures and repairs. 8 July 2024
The pattern of rupture and repair within therapeutic alliances has been associated with improved outcome. The present study adds to this body of research by examining rupture and repair from a dyadic perspective. First, we examined the relationship between mutual recognition of ruptures, rupture intensity, and client ratings of session helpfulness. We then examined client–therapist […]
Preventing dropout in spiritually integrated psychotherapies: What are the effective methods of attending to clients’ spirituality? 30 May 2024
The purpose of this study was to examine associations between clinicians’ use of varying types of spiritual interventions in the first session of spiritually integrated psychotherapies (SIPs) and clients’ likelihood of returning for a second session. In total, 154 practitioners of SIPs from 33 settings in a practice-research network reported on their implementation of different […]

Ongoing Teacher Support for Data-Based Individualization: A Meta-Analysis and Synthesis 6 September 2024
Journal of Learning Disabilities, Ahead of Print. Although data-based individualization (DBI) has positive effects on learning outcomes for students with learning difficulties, this framework can be difficult for teachers to implement due to its complexity and contextual barriers. The first aim of this synthesis was to investigate the effects of ongoing professional development (PD) support […]
Emma Shanahan
A Family-Based Intervention for Early Elementary Students With Reading and Behavioral Difficulties: A Pilot Study 2 August 2024
Journal of Learning Disabilities, Ahead of Print. We created and tested a family-based intervention with families of children in Grades 1 and 2 with reading and behavioral difficulties to investigate its impact on text comprehension. Developed with input from parents, reading experts, and behavior specialists, Family-RISE (Reading Intervention with Supports for Engagement) integrates evidence-based practices […]
Garrett J. Roberts
Assessing Beliefs About Intrinsic and Extrinsic Determinants of SLD: Evaluating the Factor Structure of a Novel Instrument 26 July 2024
Journal of Learning Disabilities, Ahead of Print. Schools conduct comprehensive psychoeducational evaluations to identify students with specific learning disabilities (SLDs) and determine whether they qualify for special education services. This decision-making process is complex and research has documented many factors influencing SLD identification decisions. One such factor may be decision-makers’ beliefs about the underlying causes […]
Courtenay A. Barrett

Item reduction of the “Support Intensity Scale” for people with intellectual disabilities, using machine learning 19 August 2024
British Journal of Learning Disabilities, EarlyView.
Félix González‐Carrasco, Felipe Espinosa Parra, Izaskun Álvarez‐Aguado, Sebastián Ponce Olguín, Vanessa Vega Córdova, Miguel Roselló‐Peñaloza
Culturally adaptive healthcare for people with a learning disability from an ethnic minority background: A qualitative synthesis 12 August 2024
British Journal of Learning Disabilities, EarlyView.
Christina Roberts, Nicola Ditzel, Nicola Cooper‐Moss, Katie Umbleby, Umesh Chauhan
In search of education, participation and inclusion: Embrace the uncertain By Jonathan Rix, Abingdon: Routledge. 2024. pp. 204. £28.79 8 August 2024
British Journal of Learning Disabilities, EarlyView.
Melanie Nind

Autism spectrum disorder, radicalization, and violence: a forensic perspective 30 August 2024
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Julian A.C. Gojer Kayla M. Gaw Kaileigh M. Chretien a Integrated Forensic Program, Royal Ottawa Mental Health Center and Institute of Mental Health Research, ON, Canadab Sexual Behaviours Clinic, Royal Ottawa Mental Health Center and Institute of Mental Health Research, ON, Canadac Integrated Forensic Program (IFP), Royal Ottawa Mental Health Center, ON, Canada
Childhood onset violence and early onset schizophrenia. A molecular diagnosis of 15q13.2-13.3 duplication syndrome and the effects on insight and engagement 28 August 2024
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Ed Silva Department missing for affiliation Rathbone Low Secure Unit, Rathbone Hospital, Mersey Care NHS FT, Liverpool, UK
Statement of Retraction: See think act: the need to rethink and refocus on relational security 19 August 2024
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Therapeutic and non-therapeutic practices in the child justice system in Kenya: A therapeutic jurisprudence perspective
Child justice systems are specialized jurisdictions set up for the purpose of providing justice related services to children. In an effort to resolve many of the systemic injustices expereinced by justice involved children, Kenya recently legislated the Children Act 2022. This new law is viewed as a paradigm shift from previous children acts as it […]
Forensic criteria, clinical and theoretical issues of the indication of court-ordered treatment: A comparative survey among experts in forensic psychiatry and sentencing judges in France
Following the French law n° 98–468 of 17 June 1998 relative to the prevention of sexual offenses and the protection of minors, social and judicial follow-up and court-ordered treatment were introduced with the aim of reinforcing the prevention of recidivism. Court-ordered treatment is one of the possible obligatory measures provided for by social and judicial […]
Editorial Board

Changing environments to promote safety in libraries
The purpose of this article is to investigate how changes in the environment of a library affect the safety conditions of both visitors and staff. Using principles of Crime Prevention Through Environmental Design, crime and incidents of public disturbance from 2017 to 2020 from libraries in Stockholm, Sweden, are analyzed and later mapped using 3D […]
Revisiting the tautology problem in rational choice theory: What it is and how to move forward theoretically and empirically
Criminological rational choice theory is blighted by tautology—that if a crime occurs, then by definition the benefits must exceed the costs. The current analysis details the nature of this tautology as well as its theoretical and philosophical implications concerning the circumstances under which offenders make rational (thoughtful and reflective) or irrational (habitual, intuitive, or instinctual) […]
Experiences of fatherhood in prison: A thematic analysis of differences between fathers in a family approach programme and a comparison group
Various programmes have been implemented in prisons to strengthen parental involvement and parent–child relationships during imprisonment. In-depth insights into such programmes are limited. This qualitative study compared the experiences of two groups of imprisoned fathers in the Netherlands: fathers who participated in a family approach programme ( = 10) and fathers in a comparison group ( = 29). Based […]

The longitudinal associations between nonviolent/violent stressful life events, moral disengagement, and online aggression in Chinese young people through the lens of general aggression model. 18 July 2024
Objective: Online aggression (OA) in Chinese university students is a public health concern. Drawing on the general aggression model (GAM), this study examines the extent to which nonviolent and violent stressful life events predict OA through altering moral cognition (i.e., moral disengagement). It also examines whether the two types of stressful life events interactively predict […]
Adolescent relationship violence: Should pushes and hits always be considered violent? 18 July 2024
Objective: Research on adolescent relationship violence often involves having adolescents report on physically forceful acts, such as pushes and hits, that have occurred in the context of dating relationships. The present study compares: (a) adolescents who reported having experienced acts of physical force by a dating partner and attributed it solely to playfulness (playful only); […]
Internalized heterosexism magnifies the association of hazardous or harmful alcohol use on intimate partner violence perpetration rates of sexual minority and same-sex-attracted men. 20 June 2024
Objective: To test whether internalized heterosexism, a form of minority stress, heightens the effect of hazardous or harmful alcohol use on frequency of intimate partner violence (IPV) perpetration among sexual minority and same-sex-attracted men. Method: We recruited participants online via Amazon Mechanical Turk (MTurk). Inclusion criteria were adult cisgender men living in the United States […]

Changes to our Editorial Team 6 September 2024
Addiction, EarlyView.
Effects of interventions to combat tobacco addiction: Cochrane update of 2021 to 2023 reviews 4 September 2024
Addiction, EarlyView.
Jonathan Livingstone‐Banks, Nicola Lindson, Jamie Hartmann‐Boyce
Age, period and cohort effects of heavy episodic drinking by sex/gender and socioeconomic position in Canada, 2000–2021 4 September 2024
Addiction, EarlyView.
Alessandra T. Andreacchi, Erin Hobin, Arjumand Siddiqi, Brendan T. Smith

A pilot study of “AKBAY” self-help intervention for university students with moderate symptoms of depression and anxiety 9 September 2024
Depression and anxiety are common mental health issues among young adults, particularly exacerbated by the COVID-19 pandemic. Research indicates a notable increase in global prevalence rates, especially in this demographic. Despite their prevalence, factors like stigma, cost and limited accessibility often prevent individuals from seeking professional help. Therefore, there is a pressing need for innovative […]
Sherna Bangalan
Defining mental health literacy: a systematic literature review and educational inspiration 2 September 2024
This paper aims to explore how the term “mental health literacy” (MHL) is defined and understand the implications for public mental health and educational interventions. An extensive search was conducted by searching PubMed, ERIC, PsycINFO, Scopus and Web of Science. Keywords such as “mental health literacy” and “definition” were used. The publication year ranges from […]
Shengnan Zeng
Representing the experiences of charity peer leaders facilitating well-being interventions to their peers using process evaluation methodology (Part 2) 2 September 2024
This paper aims to build on Part 1 which generated a theory representing the experiences of charity peer leaders facilitating well-being interventions (Burns, 2024). This study (Part 2) examines the process of peers [1] becoming peer leaders using the generated theory. Following the Medical Research Council Process Evaluation Framework (Moore et al, 2015), the methods […]
Jenny Burns

Mortality in the Victorian asylum: was it so high? Standardised Mortality Rate compared with historical methods 9 August 2024
History of Psychiatry, Ahead of Print. Mortality is closely linked to age, sex, and social and historical context. Standardised Mortality Rates (SMR) address these contextual factors by comparing mortality in a population under study with that in people of the same age and sex, the same period in history and from a similar cultural context. […]
Charlotte Richardson
The notion of excessive childhood restlessness in Spain at the beginning of the twentieth century 27 July 2024
History of Psychiatry, Ahead of Print. This study delves into the historical documentation from 1900 to 1936 by Spanish doctors and educators concerning children’s hyperactivity. By focusing on medical perspectives of the time, we aim to explore the conceptualisation of childhood phenomenology within the context of significant international literature of that era. The publications of […]
Joana Escamilla Lerner
Empathy or sympathy: a necessary distinction? 23 July 2024
History of Psychiatry, Ahead of Print. As a deeply hybrid discipline, psychiatry demands research that tackles the concepts constituting it and its objects. This is an essential prerequisite to empirical studies, the validity of which are directly dependent on a clear understanding of the underlying concepts. Empathy and sympathy are concepts used variably and inconsistently […]
Ivana S Marková

Suicide among adolescents in Brazil in times of pandemic: A perspective 5 September 2024
International Journal of Social Psychiatry, Ahead of Print.
Raphael Mendonça Guimarães
Factors predicting employment status among persons with schizophrenia: A cross-sectional study from Chennai, India 5 September 2024
International Journal of Social Psychiatry, Ahead of Print. Background:Even among other mental disorders, a diagnosis of schizophrenia is associated with an abnormally low employment rate. However, those who can find employment report mental health improvements and diminishing symptoms.Aims:In this cross-sectional study, we analyzed a variety of sociodemographic factors between groups of schizophrenia-diagnosed employed and unemployed […]
T Indhumathi
Suicidal behaviors among high school graduates with preexisting mental health problems: a machine learning and GIS-based study 5 September 2024
International Journal of Social Psychiatry, Ahead of Print. Background:Suicidal behavior among adolescents with mental health disorders, such as depression and anxiety, is a critical issue. This study explores the prevalence and predictors of past-year suicidal behaviors among Bangladeshi high school graduates, employing both traditional statistical and machine learning methods.Aims:To investigate the prevalence and predictors of […]
Firoj Al-Mamun

Development and validation of an interprofessional collaborative educational module on the self-management of foot for individuals with type II diabetes mellitus [version 2; peer review: 1 approved, 1 approved with reservations] 6 September 2024
Background Insufficient awareness of foot self-care among diabetic individuals results in diabetic foot ulcers. The management of diabetes and diabetic foot ulcers demands a well-coordinated approach that involves multiple healthcare providers (HCPs). The present study aims to develop and validate an interprofessional collaborative (IPC) educational program involving HCPs to efficiently oversee and instruct the public […]
Sushma Prabhath
Entrepreneurial mindset assessment: a systematic literature review using PRISMA model [version 1; peer review: awaiting peer review] 6 September 2024
Background An entrepreneurial mindset is widely recognized as crucial for success in today’s fast-paced competitive world. People across various sectors—businesses, schools, politics, the military, and the public— benefit from a developed entrepreneurial mindset. Consequently, an accurate entrepreneurial mind-sets is becoming increasingly vital. This systematic literature review comprehensively analyzed the research on methods used to assess […]
Mulugeta Eshete Degefu
Analytical approach to piezoelectric model synthesis with the use of Cauer’s method for system design [version 3; peer review: 3 approved with reservations] 6 September 2024
Background Piezoceramic materials have unique property which enables direct and bilateral conversion between mechanical and electrical energy. This ability facilitates significant miniaturisation of technology and opens many opportunities in design of new actuators and energy harvesters. Mathematical modelling of piezoelectric modules is notoriously hard due to complex constitutive equations defining mechanical and electrical energy conversion. […]
Jacek Harazin

Early Parathyroidectomy No Boon for Preventing Depression 6 September 2024
(MedPage Today) -- Incidence of new-onset depression was no lower for adults with primary hyperparathyroidism (PHPT) treated with early parathyroidectomy compared with nonoperative management, observational Veterans Affairs data showed. In a trial...
Physician Who Punched Officer During Capitol Riot Sentenced to Prison 6 September 2024
(MedPage Today) -- A Massachusetts medical doctor who punched a police officer during a mob's attack on the U.S. Capitol was sentenced Thursday to 9 months of imprisonment followed by 9 months of home confinement. Jacquelyn Starer, MD, was in...
Did Oregon's Drug Decriminalization Policy Increase Overdose Deaths? 6 September 2024
(MedPage Today) -- In this video interview, Brandon del Pozo, PhD, MPA, MA, of Rhode Island Hospital and Brown University in Providence, discusses his new article in JAMA Network Open, which assessed whether drug decriminalization in Oregon was...

Suspect accused of random attacks in Vancouver had a history of court-ordered psychiatric care 7 September 2024
... psychiatric services as part of a probation order in 2022 ... Eby says he's open to the return of involuntary mental health care, adding that the ...
Psychiatrist explains: Sexual activity isn't just biological, but about health and emotional balance too 7 September 2024
In a candid conversation, Dr Anshu Kulkarni, senior consultant psychiatrist, unveils the intimate link between sexual pleasure and mental health.
Burlington man accused in stabbing sought psychiatric treatment - WCAX 7 September 2024
A Burlington man ...

Not Kidding: Yellow Dye 5 May Be the Key to Invisibility 6 September 2024
A common food dye turned mice see-through, a "stunning" finding that could revolutionize imaging techniques in medicine. Medscape Medical News
KRAS Inhibitors in Pancreatic Cancer: Hope on the Horizon? 6 September 2024
In a disease with dismal outcomes, KRAS inhibitors may offer hope for treating pancreatic cancer. But with preliminary data, experts remain cautiously optimistic. Medscape Medical News
Why More Doctors Are Joining Unions 6 September 2024
With increasing private equity and a dwindling voice, more physicians are turning to unions as a way to protect their rights and advocate for better working conditions. Medscape Medical News

Gaza: 160,000 more children vaccinated against polio in southern Gaza 6 September 2024
More than 160,000 children were vaccinated in southern Gaza on Thursday, the first day of a polio vaccination campaign there, the United Nations Relief and Works Agency (UNRWA) said on Friday.
Mpox: Equitable vaccine access crucial for Global South 6 September 2024
As African countries grapple with a deadly mpox outbreak, the UN independent expert on the right to health on Friday stressed that equitable access to vaccines is crucial in the race to save lives.
Gaza: Polio vaccination campaign moves to southern areas 5 September 2024
The second phase of a two-round campaign to vaccinate over half a million young children in Gaza against polio began in Khan Younis on Thursday, the UN agency that assists Palestine refugees, UNRWA, said in a post on the social media platform X, formerly Twitter.

Eleventh meeting of the Intergovernmental Negotiating Body (INB) for a WHO instrument on pandemic prevention, preparedness and response 5 September 2024
The Eleventh meeting of the INB is to be held in hybrid format from 9-20 September 2024. The opening and closing plenary sessions of the INB are open to WHO Member States, Associate Members, Observers and regional economic integration organizations, as well all relevant stakeholders.
who.int
INB related interactive dialogues 3 September 2024
Tuesday 3 September 2024 from 10:00 – 13:00 and 14:00 – 17:00
who.int
Basic Emergency Care webinar: undergraduate to postgraduate to continuous professional development 3 September 2024
The webinar will highlight the impact of the WHO/ICRC Basic Emergency Care (BEC) training, share lived experiences from clinicians delivering and receiving BEC training and discuss how to integrate this training into undergraduate & postgraduate programs and continuous professional development.
who.int

Obesity in Adolescents: A Review 3 September 2024
This Review summarizes the current evidence regarding the epidemiology, pathophysiology, diagnosis, and treatment of obesity in adolescents, with a focus on management of obesity.
Patient Information: E-Cigarettes 3 September 2024
This JAMA Patient Page describes e-cigarettes and the potential health effects of vaping.
Prediction Models for Individualized Treatment Effects of Oxygen Targets—Reply 3 September 2024
In Reply We appreciate the letter to the editor by Dr Tu and colleagues regarding our recent analysis of 2 randomized trials to derive and externally validate individualized treatment effects of lower vs higher oxygen-saturation (Spo2) targets on mortality in mechanically ventilated critically ill adults. The authors raise 3 points, which we address here.

Navigating US participant data sharing requirements: implications for international clinical trials 6 September 2024
Despite practices and guidelines to promote the transparency of clinical trials such as the sharing of de-identified individual participant data having been discussed for years, such sharing is still the exception rather than the norm.123 However, this may change with two regulations in the US aimed at increased sharing of individual participant data. Firstly, the […]
Rafael Dal–Re, Linda–Gail Bekker, Vivekanand Jha, Anne Le Louarn, Florian Naudet
The Grenfell Tower Inquiry reveals fundamental weaknesses of governance 6 September 2024
In 2017, one of us wrote in this journal that “it is impossible to achieve a comprehensive understanding of events such as Grenfell Tower without confronting the political determinants of health and challenging the forces that shape them.” 1 Seven years later, the final report of the official inquiry into this tragedy, which killed 72 […]
Martin McKee, Isobel Braithwaite, May CI van Schalkwyk
Patient related outcome measures (PROMs) in long term conditions—is it time to bring them into routine clinical practice? 6 September 2024
In most consultations about long term conditions, healthcare professionals tend to focus on patients’ clinical outcomes or targets. Frequently missing from these discussions is how psychologically and physically challenging the day-to-day management of these conditions can be, as patients work to alleviate symptoms and reduce the risk of long term complications.1 In an era where […]
Ramzi A Ajjan, Emma Doble, Richard I G Holt, David Marrero

Development of a competency framework for health technology assessment in India 5 September 2024
IntroductionHealth technology assessment (HTA) has become a key part of assessing evidence to determine which treatments are funded. Early applications were within the centrally funded health systems of high-income countries. Recent years have seen increased use within low-income and middle-income countries, including India.1–6Increased application of HTAs has required corresponding increases in the systems’ resources that […]
Dixon, S., Tyagi, K., Singh, M., Kar, S. S., Bagepally, B. S., Prinja, S., Booth, A., Carroll, C., Sohail, A., Mehndiratta, A.
Assessing proposals to update established screening strategies 3 September 2024
The increasing use of statistical modelling and lower certainty evidence to expand screening and the aggressive marketing of multicancer early detection tests raises questions about evidence thresholds for updating existing screening recommendations.Since 2018, five of the updated cancer screening recommendations of the US Preventive Services Task Force (USPSTF) have included statistical models (breast, colorectal, lung, […]
Huffstetler, A., Lin, K. W., Harris, R. P.
Pharmacological interventions for preventing upper gastrointestinal bleeding in people admitted to intensive care units: a network meta-analysis 3 September 2024
ObjectivesTo assess the efficacy and safety of pharmacological interventions for preventing upper gastrointestinal (GI) bleeding in people admitted to intensive care units (ICUs).Design and settingSystematic review and frequentist network meta-analysis using standard methodological procedures as recommended by Cochrane for screening of records, data extraction and analysis. The Grading of Recommendations Assessment, Development and Evaluation (GRADE) […]
Toews, I., Hussain, S., Nyirenda, J. L. Z., Willis, M. A., Kantorova, L., Slezakova, S., Boltena, M. T., Peter, J. V., Fontes, L. E. S., Klugar, M., Sadeghirad, B., Meerpohl, J. J.

Podcast 6 September 2024
Unlawful Killing: Death, resistance and the fight for justice. Listen now!
Inquest
Statutory inquiry into 2,000 deaths in Essex mental health services to open 5 September 2024
3 September 2024
Inquest
Deaths in prison 3 September 2024
In this country we do not give a death sentence, but for everyone who has taken their life in prison that is exactly what they got - Mark Saunders, whose son Dean died in HMP & YOI Chelmsford in 2016 Below is a breakdown of deaths in prison in England and Wales by calendar year […]
Inquest