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Computational psychiatry: from synapses to sentience
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🌐 90 Days
AI Virtual Reality Related Evidence Matrix
Ca2+-dependent phosphodiesterase 1 regulates the plasticity of striatal spiny projection neuron glutamatergic synapses Trio preserves motor synapses and prolongs motor ability during aging Trans-synaptic association of vesicular zinc transporter 3 and Shank3 supports synapse-specific dendritic spine structure and function in mouse auditory cortex In Silico Chemical Experiments in the Age of AI: From Quantum Chemistry to Machine Learning and Back Genetic mechanisms for impaired synaptic plasticity in schizophrenia revealed by computational modeling Genetic mechanisms for impaired synaptic plasticity in schizophrenia revealed by computational modeling Astrocyte D1/D5 dopamine receptors govern non-Hebbian long-term potentiation at sensory synapses onto lamina I spinoparabrachial neurons Ultrastructural Changes of Synapses in the Hippocampus of Sprague Dawley Rat Brain following Exposure to Naphthalene Balls Advancing the understanding and treatment of post-traumatic stress disorder with computational modelling Unveiling cutting-edge developments: architectures and nanostructured materials for application in optoelectronic artificial synapses Computational methods and key considerations for in silico design of proteolysis targeting chimera (PROTACs) Computational methods and key considerations for in silico design of proteolysis targeting chimera (PROTACs) Nanobody engineering: computational modelling and design for biomedical and therapeutic applications A Data Set of Synthetic Utterances for Computational Personality Analysis Astrocytic Neuroligin-3 influences gene expression and social behavior, but is dispensable for synapse number Astrocytic Neuroligin-3 influences gene expression and social behavior, but is dispensable for synapse number A Model with Dopamine Depletion in Basal Ganglia and Cerebellum Predicts Changes in Thalamocortical Beta Oscillations Enhanced synaptic inhibition in the dorsolateral geniculate nucleus in a mouse model of glaucoma Induction of LTP mechanisms in dually innervated dendritic spines Induction of LTP mechanisms in dually innervated dendritic spines Schizophrenia interactome derived repurposable drugs and randomized control trials of two candidates Sex-specific mechanisms underlie long-term potentiation at hippocampus-medium spiny neuron synapses in the medial shell of the nucleus accumbens Distinct alterations in probabilistic reversal learning across at-risk mental state, first episode psychosis and persistent schizophrenia Heterogeneity in slow synaptic transmission diversifies Purkinje cell timing Predicting treatment response to ketamine in treatment-resistant depression using auditory mismatch negativity: Study protocol Personalized Cognitive Health in Psychiatry: Current State and the Promise of Computational Methods Deep generative spatiotemporal learning for integrating fracture mechanics in composite materials: inverse design, discovery, and optimization Dynamics of synaptic damage in severe traumatic brain injury revealed by cerebrospinal fluid SNAP-25 and VILIP-1 An evaluation of recent advancements in biological sensory organ-inspired neuromorphically tuned biomimetic devices An evaluation of recent advancements in biological sensory organ-inspired neuromorphically tuned biomimetic devices Excitatory synaptic structural abnormalities produced by templated aggregation of α-syn in the basolateral amygdala Short-term high fat diet impairs memory, exacerbates the neuroimmune response, and evokes synaptic degradation via a complement-dependent mechanism in a mouse model of Alzheimer's disease Retraction of: The presence of perforated synapses in the striatum after dopamine depletion, is this a sign of maladaptive brain plasticity? Synaptic modulation by coffee compounds: Insights into neural plasticity Misperceiving Momentum: Computational Mechanisms of Biased Striatal Reward Prediction Errors in Bipolar Disorder Misperceiving Momentum: Computational Mechanisms of Biased Striatal Reward Prediction Errors in Bipolar Disorder From computational screening to the synthesis of a promising OER catalyst Understanding Cognitive Behavioral Therapy for Psychosis Through the Predictive Coding Framework Systematic Review and Meta-Analysis of Automated Methods for Quantifying Enlarged Perivascular Spaces in the Brain Democratizing protein language models with parameter-efficient fine-tuning Interactions Between 3D Surface Shape and Material Perception Interactions Between 3D Surface Shape and Material Perception miRVim: Three-dimensional miRNA Structure Database Synaptic alterations in pyramidal cells following genetic manipulation of neuronal excitability in monkey prefrontal cortex Synaptic alterations in pyramidal cells following genetic manipulation of neuronal excitability in monkey prefrontal cortex Computational Tools for Neuronal Morphometric Analysis: A Systematic Search and Review The impact of subclinical psychotic symptoms on delay and effort discounting: Insights from behavioral, computational, and electrophysiological methods Heterogeneity in strategy use during arbitration between experiential and observational learning Neural computations in prosopagnosia Neural computations in prosopagnosia Transmural APD heterogeneity determines ventricular arrhythmogenesis in LQT8 syndrome: Insights from Bidomain computational modeling Establishing the distribution of cerebrovascular resistance using computational fluid dynamics and 4D flow MRI Excitatory to inhibitory synaptic ratios are unchanged at presymptomatic stages in multiple models of ALS A computational clinical decision-supporting system to suggest effective anti-epileptic drugs for pediatric epilepsy patients based on deep learning models using patient's medical history SBMLToolkit.jl: a Julia package for importing SBML into the SciML ecosystem Outcome prediction in metabolic dysfunction-associated steatotic liver disease using stain-free digital pathological assessment Unveiling the Mechanism of Phenamacril Resistance in F. graminearum: Computational and Experimental Insights into the C423A Mutation in FgMyoI Unveiling the Mechanism of Phenamacril Resistance in F. graminearum: Computational and Experimental Insights into the C423A Mutation in FgMyoI N-methyl-D-aspartate receptor- antibody encephalitis impairs maintenance of attention to items in working memory A multivariate to multivariate approach for voxel-wise genome-wide association analysis AI-based computational H&E staining in lymphomas A novel model for predicting postoperative liver metastasis in R0 resected pancreatic neuroendocrine tumors: integrating computational pathology and deep learning-radiomics Reliable, rapid, and remote measurement of metacognitive bias Fast inhibition slows and desynchronizes mouse auditory efferent neuron activity
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Computational psychiatry: from synapses to sentience
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Computational psychiatry: from synapses to sentience
🌐 365 Days
AI Virtual Reality Related Evidence Matrix
Current status, challenges and future prospects in computational psychiatry: a narrative review A primer on the use of computational modelling to investigate affective states, affective disorders and animal welfare in non-human animals Synaptic plasticity at the dentate gyrus granule cell to somatostatin-expressing interneuron synapses supports object location memory Microglial regulation of brain function and pathological changes Does the reliability of computational models truly improve with hierarchical modeling? Some recommendations and considerations for the assessment of model parameter reliability : Reliability of computational model parameters Toolkits for detailed and high-throughput interrogation of synapses in C. elegans Overcoming the translational crisis of contemporary psychiatry - converging phenomenological and spatiotemporal psychopathology P2Y6 receptor-dependent microglial phagocytosis of synapses during development regulates synapse density and memory Leveraging computational tools to combat malaria: assessment and development of new therapeutics Developmental Impairments of Synaptic Refinement in the Thalamus of a Mouse Model of Fragile X Syndrome Ca2+-dependent phosphodiesterase 1 regulates the plasticity of striatal spiny projection neuron glutamatergic synapses Trio preserves motor synapses and prolongs motor ability during aging Ten computational challenges in human virome studies Ten computational challenges in human virome studies How computational psychiatry can advance the understanding and treatment of obsessive-compulsive disorder Trans-synaptic association of vesicular zinc transporter 3 and Shank3 supports synapse-specific dendritic spine structure and function in mouse auditory cortex Mechanisms of age-related hearing loss at the auditory nerve central synapses and postsynaptic neurons in the cochlear nucleus Test-retest reliability of reinforcement learning parameters Endocannabinoid release at ventral hippocampal-amygdala synapses regulates stress-induced behavioral adaptation THIS EVENT HAS BEEN POSTPONED AND WILL BE REARRANGED FOR LATER IN THE YEAR Mitochondria at neuronal synapses: why are they there... In Silico Chemical Experiments in the Age of AI: From Quantum Chemistry to Machine Learning and Back Genetic mechanisms for impaired synaptic plasticity in schizophrenia revealed by computational modeling Genetic mechanisms for impaired synaptic plasticity in schizophrenia revealed by computational modeling Structural and functional reorganization of inhibitory synapses by activity-dependent cleavage of neuroligin-2 Microglia at the Tripartite Synapse during Postnatal Development: Implications for Autism Spectrum Disorders and Schizophrenia Inhibitory artificial synapses based on photoelectric co-modulation of graphene/WSe2 van der Waals heterojunctions Single-Molecule-Resolution Approaches in Synaptic Biology Synapse-specific trapping of SNARE machinery proteinsin the anesthetized Drosophila brain Ethological computational psychiatry: Challenges and opportunities MDGA2 Constrains Glutamatergic Inputs Selectively onto CA1 Pyramidal Neurons to Optimize Neural Circuits for Plasticity, Memory, and Social Behavior Presynaptic Proteins and Their Roles in Visual Processing by the Retina Astrocyte D1/D5 dopamine receptors govern non-Hebbian long-term potentiation at sensory synapses onto lamina I spinoparabrachial neurons SV2B defines a subpopulation of synaptic vesicles Out of control: computational dynamic control dysfunction in stress- and anxiety-related disorders Ultrastructural Changes of Synapses in the Hippocampus of Sprague Dawley Rat Brain following Exposure to Naphthalene Balls Advancing the understanding and treatment of post-traumatic stress disorder with computational modelling Understanding Human Cognition Through Computational Modeling Unveiling cutting-edge developments: architectures and nanostructured materials for application in optoelectronic artificial synapses Computational methods and key considerations for in silico design of proteolysis targeting chimera (PROTACs) Computational methods and key considerations for in silico design of proteolysis targeting chimera (PROTACs) Nanobody engineering: computational modelling and design for biomedical and therapeutic applications Emerging evidence of context-dependent synapse elimination by phagocytes in the CNS Computational Approaches for Connecting Maternal Stress to Preterm Birth Dynamic electrical synapses rewire brain networks for persistent oscillations and epileptogenesis Computational Study on Interlocked-Ferroelectricity-Contributed High-Performance Memristors Based on Two-Dimensional van der Waals Ferroelectric Semiconductors A computational model to characterize the time-course of response to rapid antidepressant therapies Modulation of central synapse remodeling after remote peripheral injuries by the CCL2-CCR2 axis and microglia Immune proteins C1q and CD47 may contribute to aberrant microglia-mediated synapse loss in the aging monkey brain that is associated with cognitive impairment Artificial Intelligence and Computational Biology in Gene Therapy: A Review A Data Set of Synthetic Utterances for Computational Personality Analysis Model-based and model-free mechanisms in methamphetamine use disorder Transmembrane protein 97 is a potential synaptic amyloid beta receptor in human Alzheimer's disease Astrocytic Neuroligin-3 influences gene expression and social behavior, but is dispensable for synapse number Astrocytic Neuroligin-3 influences gene expression and social behavior, but is dispensable for synapse number Development and Application of Technology for Neural Circuit Visualization - Secondary Publication The cognitive reality monitoring network and theories of consciousness Distinct SAP102 and PSD-95 nano-organization defines multiple types of synaptic scaffold protein domains at single synapses Network pharmacology combined with molecular docking and experimental verification to elucidate the effect of flavan-3-ols and aromatic resin on anxiety A Model with Dopamine Depletion in Basal Ganglia and Cerebellum Predicts Changes in Thalamocortical Beta Oscillations Enhanced synaptic inhibition in the dorsolateral geniculate nucleus in a mouse model of glaucoma Implications of variable synaptic weights for rate and temporal coding of cerebellar outputs Induction of LTP mechanisms in dually innervated dendritic spines Induction of LTP mechanisms in dually innervated dendritic spines Schizophrenia interactome derived repurposable drugs and randomized control trials of two candidates