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Br J Anaesth. 2024 Jun 25:S0007-0912(24)00341-6. doi: 10.1016/j.bja.2024.05.029. Online ahead of print.
ABSTRACT
Dexmedetomidine is increasingly used in paediatric anaesthesia practice. In this issue of the British Journal of Anaesthesia, a retrospective hospital registry study in anaesthetised children showed that intraoperative use of dexmedetomidine was dose-dependently associated with a longer postanaesthesia care unit length of stay. Dexmedetomidine administration was also associated with higher total hospital costs and higher odds of unwarranted haemodynamic effects, while the onset of emergence delirium was not reduced. Although these results could curb enthusiasm for paediatric use of dexmedetomidine, they might also trigger discussion about our approach in the postoperative period to children having received dexmedetomidine intraoperatively.
PMID:38926029 | DOI:10.1016/j.bja.2024.05.029
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Dexmedetomidine in paediatric anaesthesia: a call for action?
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Dexmedetomidine in paediatric anaesthesia: a call for action?
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Dexmedetomidine in paediatric anaesthesia: a call for action?
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Association of dexmedetomidine use with haemodynamics, postoperative recovery, and cost in paediatric anaesthesia: a hospital registry study Effect of Intravenous Dexmedetomidine Before Extubation on Emergence Delirium after Nasal Surgeries Intravenous infusion of dexmedetomidine during the surgery to prevent postoperative delirium and postoperative cognitive dysfunction undergoing non-cardiac surgery: a meta-analysis of randomized controlled trials Comparison of intranasal dexmedetomidine and ketamine for paediatric premedication: A randomized study Effectiveness of buccal administration of dexmedetomidine and ketamine combination in paediatric dental sedation: A randomized controlled clinical trial Dexmedetomidine in Palliative Care: A Versatile New Weapon Against Delirium and Pain-Systematic Review A Comparison of Efficacy between Low-dose Dexmedetomidine and Propofol for Prophylaxis of Postoperative Delirium in Elderly Patients Undergoing Hip Fracture Surgery: A Randomized Controlled Trial The effect of post-anesthetic administration of dexmedetomidine versus remifentanil on postoperative agitation of strabismus surgery in children: a randomized double-blind clinical trial Descriptive Analysis of Dexmedetomidine's Utility in a Palliative Care Unit at the End of Life Descriptive Analysis of Dexmedetomidine's Utility in a Palliative Care Unit at the End of Life Effects of different doses of intranasal dexmedetomidine on related complications and parents' satisfaction in anesthetized children: a systematic review Determining the Optimal Dosage of Dexmedetomidine for Smooth Emergence in Older Patients Undergoing Spinal Surgery: A Study of 44 Cases Evaluation of the Quality of Recovery from General Anesthesia in Dogs with Two Different Low Doses of Dexmedetomidine Modelling the economic constraints and consequences of Anaesthesia Associate expansion in the UK. 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