Technol Health Care. 2024 Aug 19. doi: 10.3233/THC-230931. Online ahead of print.

ABSTRACT

BACKGROUND: Liver cancer poses a significant health challenge due to its high incidence rates and complexities in detection and treatment. Accurate segmentation of liver tumors using medical imaging plays a crucial role in early diagnosis and treatment planning.

OBJECTIVE: This study proposes a novel approach combining U-Net and ResNet architectures with the Adam optimizer and sigmoid activation function. The method leverages ResNet’s deep residual learning to address training issues in deep neural networks. At the same time, U-Net’s structure facilitates capturing local and global contextual information essential for precise tumor characterization. The model aims to enhance segmentation accuracy by effectively capturing intricate tumor features and contextual details by integrating these architectures. The Adam optimizer expedites model convergence by dynamically adjusting the learning rate based on gradient statistics during training.

METHODS: To validate the effectiveness of the proposed approach, segmentation experiments are conducted on a diverse dataset comprising 130 CT scans of liver cancers. Furthermore, a state-of-the-art fusion strategy is introduced, combining the robust feature learning capabilities of the UNet-ResNet classifier with Snake-based Level Set Segmentation.

RESULTS: Experimental results demonstrate impressive performance metrics, including an accuracy of 0.98 and a minimal loss of 0.10, underscoring the efficacy of the proposed methodology in liver cancer segmentation.

CONCLUSION: This fusion approach effectively delineates complex and diffuse tumor shapes, significantly reducing errors.

PMID:39240595 | DOI:10.3233/THC-230931