Evidence
![](https://psychiatryai.com/wp-content/uploads/2023/04/psychiatryai_com.webp)
Case Rep Med. 2024 Aug 5;2024:8883047. doi: 10.1155/2024/8883047. eCollection 2024.
ABSTRACT
Aripiprazole is an atypical antipsychotic medication indicated for the treatment of schizophrenia and bipolar disorders. The drug has been shown to exhibit acceptable efficacy and is often preferred as a first-line psychiatric treatment option owing to its lower incidence of adverse effects. While first-generation antipsychotics are associated with extrapyramidal syndrome (EPS), atypical antipsychotics such as aripiprazole are generally associated with a lower frequency of EPS. In this case, we present a 31-year-old woman with a history of bipolar disorder who developed EPS after ingesting 200 mg of aripiprazole. Fortunately, her symptoms improved with the administration of biperiden, and she was discharged five days after ingestion. This case highlights the potential for significant consequences associated with aripiprazole, even within its therapeutic index.
PMID:39135879 | PMC:PMC11319046 | DOI:10.1155/2024/8883047
![Google](https://www.google.com/images/branding/googlelogo/2x/googlelogo_light_color_92x30dp.png)
![Google Keep](https://www.gstatic.com/images/branding/product/1x/keep_48dp.png)
![Share on Linkedin](https://psychiatryai.com/wp-content/uploads/2023/10/linkedin-logo-png-2048-1.png)
Estimated reading time: 3 minute(s)
Latest: Psychiatryai.com #RAISR4D Evidence
![](/wp-content/uploads/2024/04/bd462cc11bcf0bd0d0d6f1d0f8b7cd04-modified-1.png)
Cool Evidence: Engaging Young People and Students in Real-World Evidence
![](/wp-content/uploads/2024/04/bd462cc11bcf0bd0d0d6f1d0f8b7cd04-modified-1.png)
Real-Time Evidence Search [Psychiatry]
![](/wp-content/uploads/2024/04/pubmed.png)
AI Research
![](/wp-content/uploads/2024/05/Il5nR_nf_400x400-modified-1.png)
Extrapyramidal Syndrome due to Aripiprazole Overdose in a Young Woman: An Unusual Case Report
![](https://psychiatryai.com/wp-content/uploads/2023/04/psychiatryai_com.webp)
🌐 90 Days
AI Virtual Reality Related Evidence Matrix
A Case of Risperidone-Induced Urinary Incontinence Atypical Presentation of Ziprasidone-Induced Neuroleptic Malignant Syndrome: A Case Report Management Challenges and Potential Malabsorption of Valproic Acid in a Patient with Bipolar Disorder and Gastrointestinal History Negative Symptoms of Schizophrenia: New Prospects of Cariprazine Treatment Exposure-Response Modeling in Adults and Adolescents With Schizophrenia to Support the Extrapolation of Brexpiprazole Efficacy to Adolescents Treatment of a resistant case of schizoaffective disorder with lumateperone: A case report Recent Advances in representative small-molecule DRD2 inhibitors: Synthetic Routes and clinical applications Evidence for Therapeutic Drug Monitoring of Atypical Antipsychotics Efficacy and tolerability of brexpiprazole - a new antipsychotic drug from the group of dopamine D2 receptor partial agonists Efficacy and tolerability of brexpiprazole - a new antipsychotic drug from the group of dopamine D2 receptor partial agonists Efficacy, acceptability and tolerability of second-generation antipsychotics for behavioural and psychological symptoms of dementia: a systematic review and network meta-analysis Efficacy, acceptability and tolerability of second-generation antipsychotics for behavioural and psychological symptoms of dementia: a systematic review and network meta-analysis Rash caused by lurasidone in old chinese patient with bipolar disorder: case-based review How to treat major depressive disorder with shorter-duration hypomanic episodes? A case report Diagnosis and treatment depression in schizophrenia Drug-drug interaction and initial dosage optimization of aripiprazole in patients with schizophrenia based on population pharmacokinetics Haloperidol-induced painless legs and moving toe syndrome in a schizophrenia patient: a case report Lithium, the gold standard drug for bipolar disorder: analysis of current clinical studies Bipolar Camouflage: A Cerebellar Cognitive Affective Syndrome Case Report Remission in schizophrenia spectrum disorders: A randomized trial of amisulpride, aripiprazole and olanzapine Electric Shock Sensation and Recurrent Falls as a Side Effect of Clozapine Therapy: A Case Report Electric Shock Sensation and Recurrent Falls as a Side Effect of Clozapine Therapy: A Case Report Electric Shock Sensation and Recurrent Falls as a Side Effect of Clozapine Therapy: A Case Report Trends and off-label utilization of antipsychotics in children and adolescents from 2016 to 2021 in China: a real-world study Kufor-Rakeb syndrome-associated psychosis: a novel loss-of-function ATP13A2 variant and response to antipsychotic therapy Investigating Cannabidiol's Potential as a Supplementary Treatment for Schizophrenia: A Narrative Review Navigating Treatment Challenges: A Case Study on Refractory Psychosis in a Chronic MDMA (3,4-Methylenedioxymethamphetamine) User Effects of atypical antipsychotics on serum asprosin level and other metabolic parameters in patients with schizophrenia Improvement in depressive symptoms in a patient with severe and enduring anorexia nervosa and comorbid major depressive disorder using psychotherapy-assisted IV ketamine : a case report Cannabidiol as an antipsychotic drug Cannabidiol as an antipsychotic drug Retrospective analyses evaluating the mortality risk associated with pimavanserin or other atypical antipsychotics in patients with Parkinson disease psychosis Fahr's disease with neuropsychiatric symptoms and intermittent course: a case report Fahr's disease with neuropsychiatric symptoms and intermittent course: a case report Psychosis in Fahr Syndrome: A Case Report Continuation or maintenance ECT for schizophrenia: A narrative review of case report data Systematic Review and Network Meta-Analysis: Efficacy and Safety of Antipsychotics vs Antiepileptics or Lithium for Acute Mania in Children and Adolescents Pharmacological Treatment of Binge Eating Disorder and Frequent Comorbid Diseases High circulating MIF levels indicate the association with atypical antipsychotic-induced adverse metabolic effects On Seizures and Knives: Perampanel-Induced Psychosis: A Case Report and Literature Review "What you're born with, you die with." Half a Lifetime of Psychiatric Care for a Traumatized Young Woman With Cystic Fibrosis Ketamine Therapy in Complex Cases: A Cautionary Tale of Exacerbated Personality Traits and the Crucial Role of Comprehensive Follow-Up and Psychosocial Interventions Jessica de Souza: Prevention of Future Deaths Report Lithium and the risk of fractures in patients with bipolar disorder: A population-based cohort study Sixty years of recurrence prevention in mood disorders Expanding the phenotype of NEDAMSS with a psychiatric perspective: analysis of a new case, and a systematic review of the literature Usefulness of Gabapentin as an Alternative/Adjunct Therapy for Delirium: A Retrospective Observational Study Serotonin syndrome induced by overdose of atomoxetine alone in a patient with attention-deficit hyperactivity disorder: A case report Non-C19MC-altered embryonal tumor with multilayered rosettes in a young woman with DICER1 syndrome: case report and review of the literature Treatment of Aggressive Behavior and Agitation in an 11-Year-Old Boy with Co-Occurring Autism and ADHD: A Case Report and Literature Review on the Use of Intravenous Valproate in Emergency Psychiatry Associations between constipation risk and lifestyle, medication use, and affective symptoms in patients with schizophrenia: a multicenter cross-sectional study Associations between constipation risk and lifestyle, medication use, and affective symptoms in patients with schizophrenia: a multicenter cross-sectional study Refractory Depressive Disorder as the First Manifestation of Adolescent Sjögren's Syndrome, Successfully Treated with Rituximab Anismus-A Very Unusual Extrapyramidal Side Effect of Paliperidone Palmitate in an Adolescent with Schizo-Affective Disorder Anismus-A Very Unusual Extrapyramidal Side Effect of Paliperidone Palmitate in an Adolescent with Schizo-Affective Disorder Long-term metabolic side effects of second-generation antipsychotics in Chinese patients with schizophrenia: A within-subject approach with modelling of dosage effects Increased risk of atypical antipsychotics-induced metabolic syndrome associated with MIF CATT >5/6 among females with chronic schizophrenia Surgical Treatment of Enlarged Cervical Leiomyoma with Concomitant Uterine Prolapse: A Case Report Long prodromal symptoms of neuroleptic malignant syndrome in patient with intellectual developmental disorder-A case report Vortioxetine as a potential alternative for patients with escitalopram-induced jitteriness/anxiety syndrome: A report of three cases Parathyroid Paranoia: Unveiling Psychosis in Hyperparathyroidism Cariprazine in the management of emotionally unstable personality disorder in female patients: a case series Rare presentation of Klüver-Bucy syndrome following subarachnoid hemorrhage Rare presentation of Klüver-Bucy syndrome following subarachnoid hemorrhage
Evidence Blueprint
Extrapyramidal Syndrome due to Aripiprazole Overdose in a Young Woman: An Unusual Case Report
![](https://psychiatryai.com/wp-content/uploads/2023/04/psychiatryai_com.webp)
☊ AI-Driven Related Evidence Nodes
(recent articles with at least 5 words in title)
More Evidence
![](https://psychiatryai.com/wp-content/uploads/2023/04/psychiatryai_com.webp)
Extrapyramidal Syndrome due to Aripiprazole Overdose in a Young Woman: An Unusual Case Report
🌐 365 Days
AI Virtual Reality Related Evidence Matrix
Atypical antipsychotics in the treatment of depression in affective disorders and schizophrenia (using the aripiprazole model) Extrapyramidal adverse events and anticholinergics use after the long-term treatment of patients with schizophrenia with the new long-acting antipsychotic Risperidone ISM®: results from matching-adjusted indirect comparisons versus… Oculogyric Crisis Due to Aripiprazole Ingestion as a Suicide Attempt: A Case Report A Case of Neuroleptic Malignant Syndrome in the Context of Lithium Toxicity and Aripiprazole Use A Case of Risperidone-Induced Urinary Incontinence Atypical Presentation of Ziprasidone-Induced Neuroleptic Malignant Syndrome: A Case Report Management Challenges and Potential Malabsorption of Valproic Acid in a Patient with Bipolar Disorder and Gastrointestinal History Case report: Avoiding intolerance to antipsychotics through a personalized treatment approach based on pharmacogenetics The use of antipsychotics in obsessive compulsive disorder Dual Atypical Antipsychotics in Treatment-Resistant Schizophrenia: A Correctional Case Report and Review of Literature A comparison of recurrence rates after discontinuation of second-generation antipsychotic long-acting injectable versus corresponding oral antipsychotic in the maintenance treatment of bipolar disorder: A systematic review An Unusual Presentation of Delusional Companion Syndrome: A Case Report and Review of the Literature Negative Symptoms of Schizophrenia: New Prospects of Cariprazine Treatment Evaluating the efficacy and safety of the currently available once-every-two months long-acting injectable formulations of aripiprazole for the treatment of schizophrenia or as a maintenance monotherapy for bipolar I disorder in adults Exposure-Response Modeling in Adults and Adolescents With Schizophrenia to Support the Extrapolation of Brexpiprazole Efficacy to Adolescents Persistent hiccups due to aripiprazole: a case report and review of the literature Aripiprazole and its adverse effects in the form of impulsive-compulsive behaviors: A systematic review of case reports Efficacy and safety of aripiprazole in the treatment of delirium Treatment of a resistant case of schizoaffective disorder with lumateperone: A case report Clozapine-induced eosinophilia: A case report Recent Advances in representative small-molecule DRD2 inhibitors: Synthetic Routes and clinical applications Evidence for Therapeutic Drug Monitoring of Atypical Antipsychotics Multiple extreme overdose of antipsychotics with minimal side effects: A case report Multiple extreme overdose of antipsychotics with minimal side effects: A case report Efficacy and tolerability of brexpiprazole - a new antipsychotic drug from the group of dopamine D2 receptor partial agonists Efficacy and tolerability of brexpiprazole - a new antipsychotic drug from the group of dopamine D2 receptor partial agonists Efficacy, acceptability and tolerability of second-generation antipsychotics for behavioural and psychological symptoms of dementia: a systematic review and network meta-analysis Efficacy, acceptability and tolerability of second-generation antipsychotics for behavioural and psychological symptoms of dementia: a systematic review and network meta-analysis Aripiprazole-induced quasi-neuroleptic malignant syndrome: two case reports Clearing the Fog: A Review of Antipsychotics for Parkinson's-Related Hallucinations: A Focus on Pimavanserin, Quetiapine and Clozapine Rash caused by lurasidone in old chinese patient with bipolar disorder: case-based review A Clinical Suspicion of Quetiapine-Induced Psychosis: A Case Report and Literature Review Initiation of Aripiprazole Lauroxil Long-Acting Injectable in Adolescents During Hospitalization: A Case Series Psychotropic Management in Cotard Syndrome: Case Reports Supporting Dual Medication Management 18q Deletion Syndrome-Associated Schizophrenia: A Case Report Risperidone-Induced Leukoneutropenia: Evidence from a Positive Rechallenge and Review of the Literature Antipsychotics and the risk of diabetes and death among adults with serious mental illnesses 18q Deletion Syndrome-Associated Schizophrenia: A Case Report How to treat major depressive disorder with shorter-duration hypomanic episodes? A case report Successful Clozapine Rechallenge After Clozapine-Induced Severe Anemia: A Case Report Evidence-Based Recommendations for the Pharmacological Treatment of Women with Schizophrenia Spectrum Disorders Diagnosis and treatment depression in schizophrenia Drug-drug interaction and initial dosage optimization of aripiprazole in patients with schizophrenia based on population pharmacokinetics Population Pharmacokinetics and Dosing Simulations for Aripiprazole 2-Month Ready-to-Use Long-Acting Injectable in Adult Patients With Schizophrenia or Bipolar I Disorder A systematic review and network meta-analysis on comparative efficacy, acceptability, and safety of treatments in acute bipolar mania in youths Taste Disorder and Tongue Numbness After Lithium Overdose Peripartum cardiomyopathy in patients with psychiatric disorders successfully treated with bromocriptine: Two case reports From Unipolar to Bipolar: The Diagnostic Evolution in an Elderly Man The Janus face of antipsychotics in glial cells: Focus on glioprotection Temporal trends in antipsychotic prescriptions for pediatric patients using an administrative hospital database in Japan: a retrospective study Effectiveness and safety of second-generation antipsychotics for psychiatric disorders apart from schizophrenia: A systematic review and meta-analysis Haloperidol-induced painless legs and moving toe syndrome in a schizophrenia patient: a case report Complexities in Managing Psychosis in a Patient With Stiff-Person Syndrome: A Case Report A review on the pharmacology of cariprazine and its role in the treatment of negative symptoms of schizophrenia Catatonia-related adverse outcomes after long-acting injectable antipsychotics: Case series Review of Risk Factors, Pathophysiology, Management Principles, and Role of Medications Atypical neuroleptic malignant syndrome in an incarcerated patient: a demographic who may be at increased risk Lithium, the gold standard drug for bipolar disorder: analysis of current clinical studies Patient with Asperger's Syndrome, with episodes of fantasizing and rocking of body, treated with aripiprazole - a case report Bipolar Camouflage: A Cerebellar Cognitive Affective Syndrome Case Report A Case Report of a Patient with Soaring Clozapine Levels after Developing a Urinary Tract Infection Potential impact on mental health in patients with treatment-resistant schizophrenia - clozapine augmentation with long-acting parenteral antipsychotics: a case series Potential impact on mental health in patients with treatment-resistant schizophrenia - clozapine augmentation with long-acting parenteral antipsychotics: a case series Remission in schizophrenia spectrum disorders: A randomized trial of amisulpride, aripiprazole and olanzapine