Evidence
![](https://psychiatryai.com/wp-content/uploads/2023/04/psychiatryai_com.webp)
![Google](https://www.google.com/images/branding/googlelogo/2x/googlelogo_light_color_92x30dp.png)
![Google Keep](https://www.gstatic.com/images/branding/product/1x/keep_48dp.png)
![Share on Linkedin](https://psychiatryai.com/wp-content/uploads/2023/10/linkedin-logo-png-2048-1.png)
Estimated reading time: 1 minute(s)
Latest: Psychiatryai.com #RAISR4D Evidence
![](/wp-content/uploads/2024/04/bd462cc11bcf0bd0d0d6f1d0f8b7cd04-modified-1.png)
Cool Evidence: Engaging Young People and Students in Real-World Evidence
![](/wp-content/uploads/2024/04/bd462cc11bcf0bd0d0d6f1d0f8b7cd04-modified-1.png)
Real-Time Evidence Search [Psychiatry]
![](/wp-content/uploads/2024/04/pubmed.png)
AI Research
![](/wp-content/uploads/2024/05/Il5nR_nf_400x400-modified-1.png)
Identification of Vulnerable Interneuron Subtypes in 15q13.3 Microdeletion Syndrome Using Single-Cell Transcriptomics
![](https://psychiatryai.com/wp-content/uploads/2023/04/psychiatryai_com.webp)
🌐 90 Days
AI Virtual Reality Related Evidence Matrix
MNMST: topology of cell networks leverages identification of spatial domains from spatial transcriptomics data SpatialPrompt: spatially aware scalable and accurate tool for spot deconvolution and domain identification in spatial transcriptomics Spatiotemporal transcriptomic changes of human ovarian aging and the regulatory role of FOXP1 Molecular cascades and cell type-specific signatures in ASD revealed by single-cell genomics Molecular cascades and cell type-specific signatures in ASD revealed by single-cell genomics Single-cell dissection of the human motor and prefrontal cortices in ALS and FTLD A single-cell and spatial RNA-seq database for Alzheimer's disease (ssREAD) Clinically unfavorable transcriptome subtypes of non-WNT/non-SHH medulloblastomas are associated with a predominance in proliferating and progenitor-like cell subpopulations Clinically unfavorable transcriptome subtypes of non-WNT/non-SHH medulloblastomas are associated with a predominance in proliferating and progenitor-like cell subpopulations Hofbauer cells and fetal brain microglia share transcriptional profiles and responses to maternal diet-induced obesity Hofbauer cells and fetal brain microglia share transcriptional profiles and responses to maternal diet-induced obesity Clinical and molecular genetic analysis of a child with comorbid 16p11.2 microdeletion syndrome and Rett syndrome Artificial intelligence-assisted automatic and index-based microbial single-cell sorting system for One-Cell-One-Tube Single-cell genomics and regulatory networks for 388 human brains Single-cell genomics and regulatory networks for 388 human brains Single-cell genomics and regulatory networks for 388 human brains Library size confounds biology in spatial transcriptomics data Differential expression analysis identifies candidate synaptogenic molecules for wiring direction-selective circuits in the retina Transcriptomics of Human Brain Tissue in Parkinson's Disease: a Comparison of Bulk and Single-cell RNA Sequencing Antisense oligonucleotide therapeutic approach for Timothy syndrome Artificial Intelligence-Based Non-invasive Differentiation of Distinct Histologic Subtypes of Renal Tumors With Multiphasic Multidetector Computed Tomography Developmental trajectories of GABAergic cortical interneurons are sequentially modulated by dynamic FoxG1 expression levels Selective vulnerability of the ventral hippocampus-prelimbic cortex axis parvalbumin interneuron network underlies learning deficits of fragile X mice Single-nucleus transcriptomics uncovers a geroprotective role of YAP in primate gingival aging Characterisation of premature cell senescence in Alzheimer's disease using single nuclear transcriptomics Single-Cell Multi-Omics Map of Cell Type-Specific Mechanistic Drivers of Multiple Sclerosis Lesions Multiscale approaches for understanding single cell spatial omics data GABAergic interneurons in the hippocampal CA1 mediate contextual fear generalization in PTSD rats Understanding and manipulating the T-cell response to peptide-MHC New study reveals insight into which animals are most vulnerable to extinction due to climate change Shared inflammatory glial cell signature after stab wound injury, revealed by spatial, temporal, and cell-type-specific profiling of the murine cerebral cortex Generation of human induced pluripotent stem cell lines derived from four Rett syndrome patients with MECP2 mutations A case series of non-small cell lung cancer patients with EGFR or HER2 exon 20 insertion in Li Fraumeni syndrome A case series of non-small cell lung cancer patients with EGFR or HER2 exon 20 insertion in Li Fraumeni syndrome Decreased apoptotic priming and loss of BCL-2 dependence are functional hallmarks of Richter's syndrome Deuterium metabolic imaging differentiates glioblastoma metabolic subtypes and detects early response to chemoradiotherapy Cancer associated fibroblasts modulate the cytotoxicity of anti-cancer drugs in breast cancer: An in vitro study Spatial genomics: mapping human steatotic liver disease Analysis and Visualization of Single-Cell Sequencing Data with Scanpy and MetaCell: A Tutorial Protocol to perform integrative analysis of high-dimensional single-cell multimodal data using an interpretable deep learning technique Subpopulation commensalism promotes Rac1-dependent invasion of single cells via laminin-332 Meningioma transcriptomic landscape demonstrates novel subtypes with regional associated biology and patient outcome Meningioma transcriptomic landscape demonstrates novel subtypes with regional associated biology and patient outcome Protein Research Seminar Ependymal cells undergo astrocyte-like reactivity in response to neuroinflammation Complex regional pain syndrome: advances in epidemiology, pathophysiology, diagnosis, and treatment Insights for disease modeling from single-cell transcriptomics of iPSC-derived Ngn2-induced neurons and astrocytes across differentiation time and co-culture Prenatal 1-Nitropyrene Exposure Causes Autism-Like Behavior Partially by Altering DNA Hydroxymethylation in Developing Brain Evaluating performance and applications of sample-wise cell deconvolution methods on human brain transcriptomic data Evaluating performance and applications of sample-wise cell deconvolution methods on human brain transcriptomic data Parvalbumin interneuron cell-to-network plasticity: mechanisms and therapeutic avenues Single-cell multi-cohort dissection of the schizophrenia transcriptome Single-cell multi-cohort dissection of the schizophrenia transcriptome Microglial phagolysosome dysfunction and altered neural communication amplify phenotypic severity in Prader-Willi Syndrome with larger deletion Comparative Analysis of Single-Cell RNA Sequencing Methods with and without Sample Multiplexing scRank infers drug-responsive cell types from untreated scRNA-seq data using a target-perturbed gene regulatory network Single-cell RNA-seq reveals the role of YAP1 in prefrontal cortex microglia in depression The psychosocial impact on single mothers' well-being - A literature review Prenatal cardiac findings and 22q11.2 deletion syndrome: Fetal detection and evaluation Prenatal cardiac findings and 22q11.2 deletion syndrome: Fetal detection and evaluation scENCORE: leveraging single-cell epigenetic data to predict chromatin conformation using graph embedding Olfactory bulb anomalies in KBG syndrome mouse model and patients Molecular signatures of astrocytes and microglia maladaptive responses to acute stress are rescued by a single administration of ketamine in a rodent model of PTSD Cell type mapping of inflammatory muscle diseases highlights selective myofiber vulnerability in inclusion body myositis
Evidence Blueprint
Identification of Vulnerable Interneuron Subtypes in 15q13.3 Microdeletion Syndrome Using Single-Cell Transcriptomics
![](https://psychiatryai.com/wp-content/uploads/2023/04/psychiatryai_com.webp)
☊ AI-Driven Related Evidence Nodes
(recent articles with at least 5 words in title)
More Evidence
![](https://psychiatryai.com/wp-content/uploads/2023/04/psychiatryai_com.webp)
Identification of Vulnerable Interneuron Subtypes in 15q13.3 Microdeletion Syndrome Using Single-Cell Transcriptomics
🌐 365 Days
AI Virtual Reality Related Evidence Matrix
MNMST: topology of cell networks leverages identification of spatial domains from spatial transcriptomics data Single-cell brain organoid screening identifies developmental defects in autism hdWGCNA identifies co-expression networks in high-dimensional transcriptomics data SpatialPrompt: spatially aware scalable and accurate tool for spot deconvolution and domain identification in spatial transcriptomics Dissecting the spatiotemporal diversity of adult neural stem cells Spatiotemporal transcriptomic changes of human ovarian aging and the regulatory role of FOXP1 Integrating single-cell and spatially resolved transcriptomic strategies to survey the astrocyte response to stroke in male mice Integration of spatially opposing cues by a single interneuron guides decision-making in C. elegans Molecular cascades and cell type-specific signatures in ASD revealed by single-cell genomics Molecular cascades and cell type-specific signatures in ASD revealed by single-cell genomics Human γδ T cell Identification from Single-cell RNA Sequencing Datasets by Modular TCR Expression Developmental emergence of cortical neurogliaform cell diversity Single-cell dissection of the human motor and prefrontal cortices in ALS and FTLD A single-cell and spatial RNA-seq database for Alzheimer's disease (ssREAD) Clinically relevant molecular hallmarks of PFA ependymomas display intratumoral heterogeneity and correlate with tumor morphology Single cell spatial transcriptomics reveals distinct patterns of dysregulation in non-neuronal and neuronal cells induced by the Trem2R47H Alzheimer's risk gene mutation Leveraging spatial transcriptomics data to recover cell locations in single-cell RNA-seq with CeLEry Isolation and profiling of viable tumor cells from human ex vivo glioblastoma cultures through single-cell transcriptomics Clinically unfavorable transcriptome subtypes of non-WNT/non-SHH medulloblastomas are associated with a predominance in proliferating and progenitor-like cell subpopulations Clinically unfavorable transcriptome subtypes of non-WNT/non-SHH medulloblastomas are associated with a predominance in proliferating and progenitor-like cell subpopulations A chemist’s adventures in immunology: Probing the T-cell activation pathway at the single cell and single molecule-level with n... Hofbauer cells and fetal brain microglia share transcriptional profiles and responses to maternal diet-induced obesity Hofbauer cells and fetal brain microglia share transcriptional profiles and responses to maternal diet-induced obesity Single-cell mapping identifies MSI+ cells as a common origin for diverse subtypes of pancreatic cancer Clinical and molecular genetic analysis of a child with comorbid 16p11.2 microdeletion syndrome and Rett syndrome Advance and Application of Single-cell Transcriptomics in Auditory Research Psychiatric risk gene Transcription Factor 4 (TCF4) regulates the density and connectivity of distinct inhibitory interneuron subtypes A single-nucleus transcriptome-wide association study implicates novel genes in depression pathogenesis Single-Cell Transcriptomics and In Vitro Lineage Tracing Reveals Differential Susceptibility of Human iPSC-Derived Midbrain Dopaminergic Neurons in a Cellular Model of Parkinson's Disease Connecting genomic results for psychiatric disorders to human brain cell types and regions reveals convergence with functional connectivity A targeted sequencing extension for transcript genotyping in single-cell transcriptomics Atoh1 drives the heterogeneity of the pontine nuclei neurons and promotes their differentiation Organization of the human intestine at single-cell resolution Assembloid CRISPR screens reveal impact of disease genes in human neurodevelopment Liver Injury and Regeneration: Current Understanding, New Approaches, and Future Perspectives Investigating cell-specific effects of FMRP deficiency on spiny projection neurons in a mouse model of Fragile X syndrome Single nucleus transcriptomics of ventral midbrain identifies glial activation associated with chronic opioid use disorder Artificial intelligence-assisted automatic and index-based microbial single-cell sorting system for One-Cell-One-Tube Hypertension with hidden causes: the cognitive and behavioral profile of an adult female with chronic stress and 16p11.2 microdeletion Modeling idiopathic autism in forebrain organoids reveals an imbalance of excitatory cortical neuron subtypes during early neurogenesis A review on deep learning applications in highly multiplexed tissue imaging data analysis Single-cell genomics and regulatory networks for 388 human brains Single-cell genomics and regulatory networks for 388 human brains Single-cell genomics and regulatory networks for 388 human brains Single-molecule and single-cell epigenetics: Decoding the epigenome for cancer research and diagnostics Library size confounds biology in spatial transcriptomics data Elevated susceptibility to exogenous seizure triggers and impaired interneuron excitability in a mouse model of Leigh syndrome epilepsy COVID-19 antigen processing & T-cell response profiled by (single cell) proteomics Molecular signatures define subtypes of auditory afferents with distinct peripheral projection patterns and physiological properties Differential expression analysis identifies candidate synaptogenic molecules for wiring direction-selective circuits in the retina Dissecting viral infections, one cell at a time, by single-cell technologies A model of human neural networks reveals NPTX2 pathology in ALS and FTLD Transcriptomics of Human Brain Tissue in Parkinson's Disease: a Comparison of Bulk and Single-cell RNA Sequencing Neuropsychiatric Manifestations of Mast Cell Activation Syndrome and Response to Mast-Cell-Directed Treatment: A Case Series Single nuclei transcriptomics in diabetic mice reveals altered brain hippocampal endothelial cell function, permeability, and behavior Antisense oligonucleotide therapeutic approach for Timothy syndrome Artificial Intelligence-Based Non-invasive Differentiation of Distinct Histologic Subtypes of Renal Tumors With Multiphasic Multidetector Computed Tomography PUF60 loss-of-function with normal cognition should be considered in the differential diagnosis of Klippel-Feil syndrome Transcriptional changes in specific subsets of Drosophila neurons following inhibition of the serotonin transporter Transcriptional changes in specific subsets of Drosophila neurons following inhibition of the serotonin transporter Single-cell transcriptomics of NRAS-mutated melanoma transitioning to drug resistance reveals P2RX7 as an indicator of early drug response Modular interneuron circuits control motion sensitivity in the mouse retina Single-Nucleus RNA-Sequencing in Brain Tissue Patient Brain Organoids Identify a Link between the 16p11.2 Copy Number Variant and the RBFOX1 Gene