Evidence
Psychoneuroendocrinology. 2024 Mar 11;164:107022. doi: 10.1016/j.psyneuen.2024.107022. Online ahead of print.
ABSTRACT
Exposure to violence increases young peoples’ risk of developing mental and physical health problems. Chronic stress-related upregulation of innate immune system activity and the development of low-grade inflammation may partially underlie this health risk. However, much of the previous research has been limited to cross-sectional studies utilizing between-person analytic designs, susceptible to confounding by unmeasured factors. In this six-wave panel study of N=157 female adolescents and young adults, we tested within-person associations between interpersonal violence exposure and multiple measures of inflammatory activity. Ex vivo culture studies suggested that participants’ immune cells were more reactive to microbial stimulation and less sensitive to inhibition by glucocorticoids after violence. Numbers of circulating monocyte cells increased after violence, but serum levels of interleukin-6 and c-reactive protein did not. Findings from this within-person analysis suggest that violence exposure up-regulates innate immune system activity during adolescence and young adulthood in ways that may increase mental and physical health risk.
PMID:38518706 | DOI:10.1016/j.psyneuen.2024.107022
Estimated reading time: 3 minute(s)
Latest: Psychiatryai.com #RAISR4D Evidence
Cool Evidence: Engaging Young People and Students in Real-World Evidence
Real-Time Evidence Search [Psychiatry]
AI Research
Interpersonal violence exposure and inflammation during adolescence and young adulthood
🌐 90 Days
AI Virtual Reality Related Evidence Matrix
- Examining the Relation Between Early Violence Exposure and Firearm-Related Experiences in Emerging Adulthood: A Longitudinal Cohort Study
- Examining the Relation Between Early Violence Exposure and Firearm-Related Experiences in Emerging Adulthood: A Longitudinal Cohort Study
- Interpersonal trauma, shame, and substance use: A systematic review
- Adverse childhood experiences and subsequent physical and mental health among young adults: Results from six universities in China
- Exercise Identity and Physical Activity Behavior During Late Adolescence: A Four Wave Cross-lagged Panel Model
- Violence Against Children, Self-Harm, and Suicidal Behaviors: A Pooled and Country-Specific Analysis of Eight Low- and Middle-Income Countries
- Violence Against Children, Self-Harm, and Suicidal Behaviors: A Pooled and Country-Specific Analysis of Eight Low- and Middle-Income Countries
- Pornography exposure and access among young Australians: a cross-sectional study
- Epidemiology of violence against young children in Jamaica
- The Impact of COVID-19 and Exposure to Violent Media Content on Cyber Violence Victimization Among Adolescents in South Korea: National Population-Based Study
- Coping styles do not interact with the association between childhood trauma history and the immune-inflammatory phenotype of schizophrenia: Findings from a cross-sectional study
- Cross-regulation between the immune system and the extracellular matrix during lung pathology
- Adolescent Violence in the Home Among Youth Presenting to an Early Psychosis Service: An Exploration of Contributing Factors
- Cross-lagged relationships between exposure to intimate partner violence, depressive symptoms and suicidal thoughts among adolescent and young married women
- Cross-lagged relationships between exposure to intimate partner violence, depressive symptoms and suicidal thoughts among adolescent and young married women
- Exercise Addiction and Intimate Partner Violence: The Role of Impulsivity, Self-Esteem, and Emotional Dependence
- Intimate partner violence and posttraumatic stress disorder among adolescents and young adults in Haiti
- Experiencing violence and other predictors of within-person same-day use of multiple substances in youth: a longitudinal study in emergency settings
- Intimate partner violence and posttraumatic stress disorder among adolescents and young adults in Haiti
- Sexual violence in the workplace and associated health outcomes: a nationwide, cross-sectional analysis of women in Iceland
- Secular trends in risk factors for adolescent anxiety and depression symptoms: the Young-HUNT studies 1995-2019, Norway
- An open pilot trial of a behavioural intervention to reduce violence by young adults with early psychosis receiving treatment in an early intervention services setting: A protocol
- An open pilot trial of a behavioural intervention to reduce violence by young adults with early psychosis receiving treatment in an early intervention services setting: A protocol
- The effect of exposure to emotional violence on sexual function, sexual quality of life and psychological well-being in women: Structural equation modeling
- Global burden of self-harm and interpersonal violence and influencing factors study 1990-2019: analysis of the global burden of disease study
- No evidence, no problem? A critical interpretive synthesis of the vulnerabilities to and experiences of sexual violence among young migrants in Europe
- Mental Health Concerns During COVID-19: An Observational Study Among a Predominantly Black Community in New York City
- Firearm Violence Exposure and Functional Disability among Black Men and Women in the United States
- A nationally representative survey of ICD-11 PTSD among Danish adolescents and young adults aged 15-29
- Experiences of stigma, discrimination and violence and their impact on the mental health of health care workers during the COVID-19 pandemic
- Examining the Risks of Multiple Types of Interpersonal Victimization for Transgender and Gender Non-Conforming College Students
- Risk and Protective Factors of Self-harm and Suicidality in Adolescents: An Umbrella Review with Meta-Analysis
- Exposure to maternal experiences of IPV in early childhood and sleep health in adolescence
- The socioeconomic consequences of loneliness: Evidence from a nationally representative longitudinal study of young adults
- Exposure to Community Violence as a Mechanism Linking Neighborhood Socioeconomic Disadvantage and Neural Responses to Reward
- Trauma film viewing and intrusive memories: Relationship between salivary alpha amylase, endocannabinoids, and cortisol
- National and regional prevalence of interpersonal violence from others' alcohol use: a systematic review and modelling study
- Work-, lifestyle-, and health-related factors among women and men working in the emergency medical services
- Community exposure to gun homicide and adolescents' educational aspirations
- The emerging neuroimmune hypothesis of bipolar disorder: An updated overview of neuroimmune and microglial findings
- Trauma-focused treatments for victims of interpersonal violence: A comparison of treatment interventions and outcomes
- Hypoxia inducible factor-1a regulates microglial innate immune memory and the pathology of Parkinson's disease
- Longitudinal Change in Appearance-Related Social Media Consciousness and Depressive Symptoms: A Within-Person Analysis during Early-to-Middle Adolescence
- Examining within-person associations between alcohol and cannabis use and hooking up among adolescents and young adults in the United States
- The immune system in Parkinson's disease: what we know so far
- Adolescent leisure-time physical activity and eating disorders: a longitudinal population-based twin study
- Long-term effects of the school context on depressive symptoms among Asian Americans
- From childhood maltreatment to intimate partner violence perpetration: A prospective longitudinal examination of the roles of executive functioning and self-esteem
- Neural responses to gaming content on social media in young adults
- Resting heart rate associations with violence exposure and posttraumatic stress symptoms: sex differences in children
- Fear of violence and working department influences physical aggression level among nurses in northwest Ethiopia government health facilities
- Air and Noise Pollution Exposure in Early Life and Mental Health From Adolescence to Young Adulthood
- Inflammatory mediators in major depression and bipolar disorder
- People with intellectual disability and their risk of exposure to violence: Identification and prevention - a literature review
- Prevalence and Correlates of Exposure (Direct and Indirect) to Perceived Racism-Based Police Violence among Black Emerging Adult College Students
- The unique role of adolescent internalizing and externalizing problems, and maternal-adolescent communication in their association with attachment in early adulthood
- Interpersonal communication and perceived norms as social influence mechanisms of e-cigarette use among adults: a systematic review
- Interpersonal communication and perceived norms as social influence mechanisms of e-cigarette use among adults: a systematic review
- Firearm violence exposure and health in 2 national samples of Black and American Indian/Alaska Native adults
- Association between threat-related adverse childhood experiences and chronic lung diseases in a middle and older aged population: A cross-sectional and longitudinal study in China
- Association between threat-related adverse childhood experiences and chronic lung diseases in a middle and older aged population: A cross-sectional and longitudinal study in China
- Hair cortisol determinants in 11-year-old children: Environmental, social and individual factors
- Hair cortisol determinants in 11-year-old children: Environmental, social and individual factors
- Local gun violence, mental health, and sleep: A neighborhood analysis in one hundred US Cities
Evidence Blueprint
Interpersonal violence exposure and inflammation during adolescence and young adulthood
☊ AI-Driven Related Evidence Nodes
(recent articles with at least 5 words in title)
More Evidence
Interpersonal violence exposure and inflammation during adolescence and young adulthood
🌐 365 Days
AI Virtual Reality Related Evidence Matrix
- Examining the Relation Between Early Violence Exposure and Firearm-Related Experiences in Emerging Adulthood: A Longitudinal Cohort Study
- Examining the Relation Between Early Violence Exposure and Firearm-Related Experiences in Emerging Adulthood: A Longitudinal Cohort Study
- Sex-specific associations between co-exposure to multiple metals and externalizing symptoms in adolescence and young adulthood
- Killing pain? A prospective population-based study on trauma exposure in childhood as predictor for frequent use of over-the-counter analgesics in young adulthood. The HUNT study
- Predictors of early adulthood insomnia following exposure to a single mass violence attack during adolescence: 7-13 year follow-up from the Utøya and HUNT studies
- Interpersonal trauma, shame, and substance use: A systematic review
- Exposure to violence in childhood and risk of violence in adult schizophrenia: Results from a multinational study
- Adverse childhood experiences and subsequent physical and mental health among young adults: Results from six universities in China
- Exercise Identity and Physical Activity Behavior During Late Adolescence: A Four Wave Cross-lagged Panel Model
- Violence Against Children, Self-Harm, and Suicidal Behaviors: A Pooled and Country-Specific Analysis of Eight Low- and Middle-Income Countries
- Violence Against Children, Self-Harm, and Suicidal Behaviors: A Pooled and Country-Specific Analysis of Eight Low- and Middle-Income Countries
- Longitudinal associations among experiences of sexual assault, posttraumatic stress disorder symptoms, and heavy drinking in young adults
- Pornography exposure and access among young Australians: a cross-sectional study
- Epidemiology of violence against young children in Jamaica
- The Impact of COVID-19 and Exposure to Violent Media Content on Cyber Violence Victimization Among Adolescents in South Korea: National Population-Based Study
- Coping styles do not interact with the association between childhood trauma history and the immune-inflammatory phenotype of schizophrenia: Findings from a cross-sectional study
- Cross-regulation between the immune system and the extracellular matrix during lung pathology
- Armed conflict exposure and mental health: examining the role of imperceptible violence
- Adolescent Violence in the Home Among Youth Presenting to an Early Psychosis Service: An Exploration of Contributing Factors
- Cross-lagged relationships between exposure to intimate partner violence, depressive symptoms and suicidal thoughts among adolescent and young married women
- Cross-lagged relationships between exposure to intimate partner violence, depressive symptoms and suicidal thoughts among adolescent and young married women
- Adolescent restraint stress enhances adult nicotine reinforcement in male and female rats
- Examination of proinflammatory activity as a moderator of the relation between momentary interpersonal stress and suicidal ideation
- Neuroimmune mechanisms connecting violence with internalizing symptoms: A high-dimensional multimodal mediation analysis
- Exercise Addiction and Intimate Partner Violence: The Role of Impulsivity, Self-Esteem, and Emotional Dependence
- Neural differentiation of emotional faces as a function of interpersonal violence among adolescent girls
- PTSD increases risk for major adverse cardiovascular events through neural and cardio-inflammatory pathways
- Examining Associations Between School Connectedness, Social Support, Violence, and Firearm Carrying
- Intimate partner violence and posttraumatic stress disorder among adolescents and young adults in Haiti
- Experiencing violence and other predictors of within-person same-day use of multiple substances in youth: a longitudinal study in emergency settings
- Intimate partner violence and posttraumatic stress disorder among adolescents and young adults in Haiti
- Thoughts of self-harm in adolescents: Relationship with violence in the Dominican Republic
- Elevations in Blood Pressure Associated with Exposure to Violence are Mitigated by Pro-gun-Carrying Attitudes among Street-Identified Black Males and Females
- Sexual violence in the workplace and associated health outcomes: a nationwide, cross-sectional analysis of women in Iceland
- Exploring the effect of early menarche on sexual violence among adolescent girls and young women in southeastern Ghana: a longitudinal mediation analysis
- Impact of violence against women on quality of life and menopause-related disorders
- Identifying high-risk subgroups for self-harm in adolescents and young adults: A longitudinal latent class analysis of risk factors
- Secular trends in risk factors for adolescent anxiety and depression symptoms: the Young-HUNT studies 1995-2019, Norway
- An open pilot trial of a behavioural intervention to reduce violence by young adults with early psychosis receiving treatment in an early intervention services setting: A protocol
- An open pilot trial of a behavioural intervention to reduce violence by young adults with early psychosis receiving treatment in an early intervention services setting: A protocol
- Symptoms of depression and internalizing problems in early adulthood - associated factors from birth to adolescence
- The effect of exposure to emotional violence on sexual function, sexual quality of life and psychological well-being in women: Structural equation modeling
- Interpersonal violence and suicide risk: Examining buffering effects of school and community connectedness
- Individual and Cumulative Firearm Violence Exposure: Implications for Sleep among Black and American Indian/Alaska Native Adults
- Domestic violence and its psychological consequences during the COVID-19 pandemic-key findings from German-speaking countries
- Global burden of self-harm and interpersonal violence and influencing factors study 1990-2019: analysis of the global burden of disease study
- Interpersonal Trauma Effects on Adolescent Depression: The Moderating Role of Neurophysiological Responses to Positive Interpersonal Images
- Exposure to Neighborhood Violence and Gun Carrying Among Adolescents in the United States: Findings From A Population-Based Study
- No evidence, no problem? A critical interpretive synthesis of the vulnerabilities to and experiences of sexual violence among young migrants in Europe
- Dynamic Associations Between Anxiety Symptoms and Drinking Behavior From Early Adolescence to Young Adulthood
- The effect of inflammation, SARS-CoV-2 infection, age and mental health on serotonin, and kynurenine and catecholamine pathway metabolites
- Gun Violence on Walkable Routes to and from School: Recommendations for Policy and Practice
- Mental Health Concerns During COVID-19: An Observational Study Among a Predominantly Black Community in New York City
- Firearm Violence Exposure and Functional Disability among Black Men and Women in the United States
- A life course health development model of HIV vulnerabilities and resiliencies in young transgender women in Peru
- A nationally representative survey of ICD-11 PTSD among Danish adolescents and young adults aged 15-29
- Association of workplace violence and bullying with later suicide risk: a multicohort study and meta-analysis of published data
- Experiences of stigma, discrimination and violence and their impact on the mental health of health care workers during the COVID-19 pandemic
- Identifying latent themes in suicide among black and white adolescents and young adults using the National Violent Death Reporting System, 2013-2019
- Examining the Risks of Multiple Types of Interpersonal Victimization for Transgender and Gender Non-Conforming College Students
- Distress about social problems and tobacco and cannabis use outcomes among young adults in Los Angeles County
- Supportive Relationships Mitigate the Effect of Cumulative Exposure to Adverse Childhood Experiences on Depression, Anxiety, Stress, and Suicide Considerations-The Arizona Youth Risk Behavior Survey
- Lifetime Interpersonal Violence or Abuse and Diabetes Rates by Sex and Race
- ACEs and mental health problems as suicidality predictors in Mexican adolescents