Evidence
Biomed Pharmacother. 2024 May 2;175:116687. doi: 10.1016/j.biopha.2024.116687. Online ahead of print.
ABSTRACT
World Drug Report 2023 concluded that 296 million people abused drugs, 39.5 million became addiction and 494,000 died as a direct or indirect result of addiction. Addiction has become a growing problem that affects individuals, their families, societies, countries and even the world. However, treatment for addiction is only limited to some developed countries because of the high cost, difficult implementation, and time consuming. Therefore, there is an urgent need to develop a low-cost, effective drug for the development of addiction treatment in more countries, which is essential for the stability and sustainable development of the world. In this review, it provided an overview of the abuse of common addictive drugs, related disorders, and current therapeutic regimen worldwide, and summarized the mechanisms of drug addiction as reward circuits, neuroadaptation and plasticity, cognitive decision-making, genetics, and environment. According to their chemical structure, 43 natural products and 5 herbal combinations with potential to treat addiction were classified, and their sources, pharmacological effects and clinical trials were introduced. It was also found that mitragine, ibogine, L-tetrahydropalmatine and crocin had greater potential for anti-addiction.
PMID:38701568 | DOI:10.1016/j.biopha.2024.116687
Estimated reading time: 4 minute(s)
Latest: Psychiatryai.com #RAISR4D Evidence
Cool Evidence: Engaging Young People and Students in Real-World Evidence
Real-Time Evidence Search [Psychiatry]
AI Research
Natural products as the therapeutic strategies for addiction
🌐 90 Days
AI Virtual Reality Related Evidence Matrix
- In Support of the Decriminalization of Personal Drug and Paraphernalia Use and Possession: Position Statement of AMERSA, Inc (Association for Multidisciplinary Education, Research, Substance Use and Addiction)
- In Support of the Decriminalization of Personal Drug and Paraphernalia Use and Possession: Position Statement of AMERSA, Inc (Association for Multidisciplinary Education, Research, Substance Use and Addiction)
- Excess mortality among individuals who have undergone addiction treatment: a study from Greenland
- Excess mortality among individuals who have undergone addiction treatment: a study from Greenland
- Excess mortality among individuals who have undergone addiction treatment: a study from Greenland
- The characteristics of prevention of drug addiction and narcotism in municipal formation of city of Novorossiysk
- Measurement invariance of the Facebook intrusion questionnaire across 25 countries
- Exploring Health Informatics in the Battle against Drug Addiction: Digital Solutions for the Rising Concern
- Harm Reduction as a Form of 'Wrap-Around' Care: The Nursing Role
- GABA system in the prefrontal cortex involved in psychostimulant addiction
- The Incentive-Sensitization Theory of Addiction 30 Years On
- The distribution of neurotransmitters in the brain circuitry: mesolimbic pathway and addiction
- Relationship between awareness of digital game addiction, health literacy, and sociodemographic characteristics of mothers: A structural equation modeling analysis
- Neuronal biomarkers as potential therapeutic targets for drug addiction related to sex differences in the brain: Opportunities for personalized treatment approaches
- Work addiction and personality organization: Results from a representative, three-wave longitudinal study
- Motivated reasoning and scientific racism in compulsion theory of human addiction: Methodological framework to promote social justice
- Young people's experiences of addiction to nicotine vaping products: A qualitative analysis from Aotearoa New Zealand
- Racism, not race: Quantitative analysis of the use of race and racism in the addiction literature
- Racism, not race: Quantitative analysis of the use of race and racism in the addiction literature
- Racism, not race: Quantitative analysis of the use of race and racism in the addiction literature
- Racism, not race: Quantitative analysis of the use of race and racism in the addiction literature
- Microelectrode recording characterization of the nucleus accumbens and the anterior limb of internal capsule in patients with addiction
- Prevalence and correlates of suicide attempts in Chinese outpatients with first-episode and drug-naive psychotic major depressive disorder at different ages of onset
- Evaluation of nurses' attitudes and behaviors regarding narcotic drug safety and addiction: a descriptive cross-sectional study
- Evaluation of nurses' attitudes and behaviors regarding narcotic drug safety and addiction: a descriptive cross-sectional study
- Systematic review on the characteristics and efficacy of school preventive programs for drug addiction in Spain
- Heterogeneity in choice models of addiction: the role of context
- Elucidating the molecular symphony: unweaving the transcriptional & epigenetic pathways underlying neuroplasticity in opioid dependence and withdrawal
- Elucidating the molecular symphony: unweaving the transcriptional & epigenetic pathways underlying neuroplasticity in opioid dependence and withdrawal
- The autoimmune nature of morphine addiction
- Analysis of the causes, psychological mechanisms, and coping strategies of short video addiction in China
- Direct and indirect effects of economic sanctions on health: a systematic narrative literature review
- Harnessing the power of nature exposure to mitigate adolescents' Internet addiction: A chain mediation model
- Adolescents' short-form video addiction and sleep quality: the mediating role of social anxiety
- Adolescents' short-form video addiction and sleep quality: the mediating role of social anxiety
- Comments on "Anorexia nervosa: An addiction? Application of the addiction model to eating"
- Comments on "Anorexia nervosa: An addiction? Application of the addiction model to eating"
- Comments on "Anorexia nervosa: An addiction? Application of the addiction model to eating"
- Comments on "Anorexia nervosa: An addiction? Application of the addiction model to eating"
- Comments on "Anorexia nervosa: An addiction? Application of the addiction model to eating"
- Types of short video addiction among college freshmen: Effects on career adaptability, insomnia, and depressive symptoms
- Types of short video addiction among college freshmen: Effects on career adaptability, insomnia, and depressive symptoms
- Development of the Food Addiction Symptom Inventory: The first clinical interview to assess ultra-processed food addiction
- Development of the Food Addiction Symptom Inventory: The first clinical interview to assess ultra-processed food addiction
- Development of the Food Addiction Symptom Inventory: The first clinical interview to assess ultra-processed food addiction
- Adult symptoms of ASD in relation to excessive internet use: The roles of ADHD symptoms and negative mood
- Implications of Impulsivity on Criminal Behavior in Individuals With Substance Use Disorder
- Memory Reconsolidation Updating in Substance Addiction: Applications, Mechanisms, and Future Prospects for Clinical Therapeutics
- Clinical Manifestations' Spectrum of Smartphone Addiction: Moving from an Addiction toward a Clinical Syndrome
- Enhancing response inhibition behavior through tDCS intervention in college students with smartphone addiction
- Enhancing response inhibition behavior through tDCS intervention in college students with smartphone addiction
- Social context and drug cues modulate inhibitory control in cocaine addiction: involvement of the STN evidenced through functional MRI
- Similarities and differences in dynamic properties of brain networks between internet gaming disorder and tobacco use disorder
- Developing an Evidence-Based Patient Education Guide on Pain Management for Asian Patients on Hospice
- The versatile binding landscape of the TAAR1 pocket for LSD and other antipsychotic drug molecules
- Does internet addiction affect the level of emotional intelligence among nursing students? A cross-sectional study
- A Descriptive Analysis of Beliefs About Nicotine and Switching to Noncombustibles Among Adults Who Smoke Cigarettes and Believe Nicotine Causes Cancer
- A Descriptive Analysis of Beliefs About Nicotine and Switching to Noncombustibles Among Adults Who Smoke Cigarettes and Believe Nicotine Causes Cancer
- The relationship between internet addiction and fear of childbirth in pregnant women
- Food Addiction Screening, Diagnosis and Treatment: A Protocol for Residential Treatment of Eating Disorders, Substance Use Disorders and Trauma-Related Psychiatric Comorbidity
- Prevalence of mobile phone addiction and poor mental health, and factors associated with mental health among medical students in Southeast Iran
- Prevalence of mobile phone addiction and poor mental health, and factors associated with mental health among medical students in Southeast Iran
- Exploring the association between internet addiction and time management among undergraduate nursing students
- Exploring the association between internet addiction and time management among undergraduate nursing students
Evidence Blueprint
Natural products as the therapeutic strategies for addiction
☊ AI-Driven Related Evidence Nodes
(recent articles with at least 5 words in title)
More Evidence
Natural products as the therapeutic strategies for addiction
🌐 365 Days
AI Virtual Reality Related Evidence Matrix
- Drug addiction and treatment: An epigenetic perspective
- Microglia in neuroimmunopharmacology and drug addiction
- Drug addictions in Malaysia: a mini-review on drug types, rehabilitation centers and therapeutic programs
- Evaluation of clinical knowledge of drugs causing addiction and associated social determinants among male pharmacy and nursing students in Riyadh, Saudi Arabia - A Cross-Sectional study
- In Support of the Decriminalization of Personal Drug and Paraphernalia Use and Possession: Position Statement of AMERSA, Inc (Association for Multidisciplinary Education, Research, Substance Use and Addiction)
- In Support of the Decriminalization of Personal Drug and Paraphernalia Use and Possession: Position Statement of AMERSA, Inc (Association for Multidisciplinary Education, Research, Substance Use and Addiction)
- An economon model of drug addiction
- Excess mortality among individuals who have undergone addiction treatment: a study from Greenland
- Excess mortality among individuals who have undergone addiction treatment: a study from Greenland
- Excess mortality among individuals who have undergone addiction treatment: a study from Greenland
- Vaccines to Treat Substance Use Disorders: Current Status and Future Directions
- The characteristics of prevention of drug addiction and narcotism in municipal formation of city of Novorossiysk
- Measurement invariance of the Facebook intrusion questionnaire across 25 countries
- Childhood maltreatment and Internet addiction among Chinese adolescents: A moderated mediation model
- Exploring Health Informatics in the Battle against Drug Addiction: Digital Solutions for the Rising Concern
- Transcranial Electrical Neurostimulation as a Potential Addiction Treatment
- Harm Reduction as a Form of 'Wrap-Around' Care: The Nursing Role
- Growing propensity of internet addiction among Asian college students: meta-analysis of pooled prevalence from 39 studies with over 50,000 participants
- Multiscale topology in interactomic network: from transcriptome to antiaddiction drug repurposing
- Linking drug and food addiction: an overview of the shared neural circuits and behavioral phenotype
- Experience of Personal Loss Due to Drug Overdose Among US Adults
- Experience of Personal Loss Due to Drug Overdose Among US Adults
- GABA system in the prefrontal cortex involved in psychostimulant addiction
- Ego Function Assessment and Internet Addiction
- The Associations between Obsessive Compulsive Personality Traits, Self-Efficacy, and Exercise Addiction
- The Incentive-Sensitization Theory of Addiction 30 Years On
- The Dual Systems Model-Impulsivity and Narcissism as the Reflexive System and Self-Regulation as the Reflective System-of Smartphone Addiction
- Current perspectives on brain circuits involved in food addiction-like behaviors
- The effect of childhood harshness and unpredictability on Internet addiction among college students: The mediating effect of self-control
- The distribution of neurotransmitters in the brain circuitry: mesolimbic pathway and addiction
- "anything may come": alcohol addiction through Sándor Weöres' oeuvre and life facts
- New Approaches to Addiction Treatment Based on Learning and Memory
- Sex and national differences in internet addiction in Egypt and Saudi Arabia
- Relationship between awareness of digital game addiction, health literacy, and sociodemographic characteristics of mothers: A structural equation modeling analysis
- Neuronal biomarkers as potential therapeutic targets for drug addiction related to sex differences in the brain: Opportunities for personalized treatment approaches
- Corrigendum to "Association of histone modification with the development of schizophrenia" [Biomed. Pharmacotherapy, vol. 175, June 2024 116747]
- Work addiction and personality organization: Results from a representative, three-wave longitudinal study
- Motivated reasoning and scientific racism in compulsion theory of human addiction: Methodological framework to promote social justice
- Online photography intervention reduces internet addiction during COVID-19: A randomised controlled trial
- Young people's experiences of addiction to nicotine vaping products: A qualitative analysis from Aotearoa New Zealand
- Racism, not race: Quantitative analysis of the use of race and racism in the addiction literature
- Racism, not race: Quantitative analysis of the use of race and racism in the addiction literature
- Racism, not race: Quantitative analysis of the use of race and racism in the addiction literature
- Racism, not race: Quantitative analysis of the use of race and racism in the addiction literature
- Microelectrode recording characterization of the nucleus accumbens and the anterior limb of internal capsule in patients with addiction
- Differences in Screen Addiction in the Past 15 Years
- Mobile phone addiction and academic burnout: the mediating role of technology conflict and the protective role of mindfulness
- Construction of influencing factor segmentation and intelligent prediction model of college students' cell phone addiction model based on machine learning algorithm
- Digital Addiction and Related Factors among College Students
- Prevalence and correlates of suicide attempts in Chinese outpatients with first-episode and drug-naive psychotic major depressive disorder at different ages of onset
- Neural Network Dynamics and Brain Oscillations Underlying Aberrant Inhibitory Control in Internet Addiction
- Evaluation of nurses' attitudes and behaviors regarding narcotic drug safety and addiction: a descriptive cross-sectional study
- Evaluation of nurses' attitudes and behaviors regarding narcotic drug safety and addiction: a descriptive cross-sectional study
- Systematic review on the characteristics and efficacy of school preventive programs for drug addiction in Spain
- Heterogeneity in choice models of addiction: the role of context
- Elucidating the molecular symphony: unweaving the transcriptional & epigenetic pathways underlying neuroplasticity in opioid dependence and withdrawal
- Elucidating the molecular symphony: unweaving the transcriptional & epigenetic pathways underlying neuroplasticity in opioid dependence and withdrawal
- An Implementation Approach to Translating Assessment Data into Treatment for Disorders of Addiction
- Modulation of Nicotine-Associated Behaviour in Rats By μ-Opioid Signals from the Medial Prefrontal Cortex to the Nucleus Accumbens Shell
- The autoimmune nature of morphine addiction
- Analysis of the causes, psychological mechanisms, and coping strategies of short video addiction in China
- Direct and indirect effects of economic sanctions on health: a systematic narrative literature review
- Reduced neural encoding of utility prediction errors in cocaine addiction
- Harnessing the power of nature exposure to mitigate adolescents' Internet addiction: A chain mediation model