PURPOSE OF REVIEW: The purpose of this review is to highlight a clinical-anatomical approach to localizing neuro-ophthalmic manifestations of associated autoimmune disorders.
RECENT FINDINGS: Our understanding of autoimmune conditions has changed considerably over recent years, particularly with the emergence of novel autoantibodies. Cardinal neuro-ophthalmic signs and symptoms of antibody-mediated autoimmune disorders have been well characterized; knowledge thereof may be the first step towards an accurate diagnosis.
SUMMARY: A thorough history, further refined by a comprehensive examination are cornerstones to disease localization in clinical medicine. Taken together, these essential steps both guide investigations and facilitate early recognition of autoimmune disorders. From a neuro-ophthalmic perspective, it is important to understand heralding signs and symptoms of autoimmune syndromes, avoid cognitive errors, and remain mindful of common diagnostic pitfalls to optimize care.
eNeuro. 2024 Jul 16:ENEURO.0372-23.2024. doi: 10.1523/ENEURO.0372-23.2024. Online ahead of print.ABSTRACTThe electrophysiological response to rewards recorded during laboratory tasks has been well documented, yet little is...
Biol Res. 2024 Jul 16;57(1):46. doi: 10.1186/s40659-024-00523-z.ABSTRACTBACKGROUND: The nucleus incertus (NI) was originally described by Streeter in 1903, as a midline region in the floor...
Biol Res. 2024 Jul 16;57(1):46. doi: 10.1186/s40659-024-00523-z.ABSTRACTBACKGROUND: The nucleus incertus (NI) was originally described by Streeter in 1903, as a midline region in the floor...
Elife. 2024 Jul 16;13:e100251. doi: 10.7554/eLife.100251.ABSTRACTBehavioral and pharmaceutical interventions reverse defects associated with increased cerebellar long-term depression in a mouse model of Fragile X syndrome.PMID:39012692...
Methods Mol Biol. 2024;2842:309-321. doi: 10.1007/978-1-0716-4051-7_16.ABSTRACTModern neuroscience research is increasingly discovering that alterations in epigenetic states within key brain cells is correlated with brain diseases....
Methods Mol Biol. 2024;2842:129-152. doi: 10.1007/978-1-0716-4051-7_6.ABSTRACTEpigenetic regulation is intrinsic to basic neurobiological function as well as neurological disease. Regulation of chromatin-modifying enzymes in the brain...
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