Neuropsychiatry of Histaminergic Circuits: Potential Role of Novel H3 Receptor Selective Antagonist/Inverse Agonist Pitolisant in Prader-Willi Syndrome

12 July 2024

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Psychopharmacol Bull. 2024 Jul 8;54(3):103-107.

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PMID:38993657 | PMC:PMC11235577

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Jeffrey CL Looi
The 2024-2025 Commonwealth Budget for Mental Health: Funding unproven initiatives and stings in the tail 2 August 2024
Australasian Psychiatry, Ahead of Print. We discuss the ramifications of the Commonwealth of Australia Budget allocations for mental healthcare for 2024–2025. There is funding for population-based mental health initiatives for milder anxiety and depression but no direct funding of services for the most severe and disabling forms of mental illness, other than pre-existing state/territory disbursements […]
Jeffrey CL Looi
Comparing the trends of MBS telepsychiatry and consultant physician telehealth services from 2017 to 2022: A retrospective study 1 August 2024
Australasian Psychiatry, Ahead of Print. ObjectiveThe Medicare Benefit Schedule (MBS) telehealth items were expanded in March 2020 during the COVID-19 pandemic. We measured the use of MBS telepsychiatry items compared to consultant physician telehealth items within the context of these item changes, to understand differences in telepsychiatry and physician telehealth utilisation.MethodsMonthly counts of face-to-face and […]
Luke S-C Woon

Evaluating counselling skills of community health workers for pregnant adolescents in Limpopo province 30 July 2024
Background: Adolescent pregnancy carries significant global ramifications. Community health workers (CHWs) play a role in empowering adolescents through counselling skills, thereby promoting informed decision-making for better outcomes.Aim: The study aims to evaluate the counselling skills of CHWs in their efforts to support pregnant adolescents (PA) in Limpopo province.Setting: The research was carried out with CHWs in the Mopani […]
Rakgadi G. Malapela
Cannabis use among hospitalised adolescents before and after decriminalisation in South Africa 26 July 2024
Background: Cannabis is the most widely used substance worldwide, and its use is much higher among adolescents. However, adolescents are at higher risk of negative sequelae secondary to this use, including the possible development of mental disorders. On 31 March 2017, the South African High Court ruled that cannabis use by an adult in a private […]
Michelle C. Swartz
The prevalence of anxiety in pregnant women at Chris Hani Baragwanath Academic Hospital 23 July 2024
Background: Non-psychotic mental disorders are common during the perinatal period. In South Africa, there are few studies on antenatal anxiety and these results vary. Antenatal anxiety does not only add to the burden of perinatal co-morbidity but has subsequent immediate and long-term effects on the mother, birth outcomes and her offspring.Aim: The aim of this study was […]
Lisha Narayan

Rasd2 regulates depression-like behaviors via DRD2 neurons in the prelimbic cortex afferent to nucleus accumbens core circuit 3 August 2024
Molecular Psychiatry, Published online: 03 August 2024; doi:10.1038/s41380-024-02684-5Rasd2 regulates depression-like behaviors via DRD2 neurons in the prelimbic cortex afferent to nucleus accumbens core circuit
Ziqian Cheng
Systematic review and meta-analysis on the effects of chronic peri-adolescent cannabinoid exposure on schizophrenia-like behaviour in rodents 2 August 2024
Molecular Psychiatry, Published online: 02 August 2024; doi:10.1038/s41380-024-02668-5Systematic review and meta-analysis on the effects of chronic peri-adolescent cannabinoid exposure on schizophrenia-like behaviour in rodents
Zhikun Li
Microglial type I interferon signaling mediates chronic stress-induced synapse loss and social behavior deficits 2 August 2024
Molecular Psychiatry, Published online: 02 August 2024; doi:10.1038/s41380-024-02675-6Microglial type I interferon signaling mediates chronic stress-induced synapse loss and social behavior deficits
Ashutosh Tripathi

Thalamic cells and pathway for social memory processing and storage
In this issue of , Wang et al. demonstrate that parvalbumin interneurons in the sensory thalamic reticular nucleus are necessary and sufficient for regulating social memory in mice, identify a novel cortico-reticular thalamic-parafascicular pathway for social cognition, and highlight an essential role of GABAergic inhibitory neurons in social memory engrams.In this issue of , Wang et al. […]
Pupil constriction by contrast for contrast
The pupil is the eye’s adjustable aperture. Fitzpatrick et al. find that visual contrast constricts the pupil, increasing contrast. This process improves behavioral performance. Its retinal origin has unorthodox elements, like interneurons that make connections in unusual locales and photoreceptive ganglion cells.The pupil is the eye’s adjustable aperture. Fitzpatrick et al. find that visual contrast constricts the […]
Dissecting attention: Rate modulation vs. phase locking
In this issue of , Spyropoulos et al. report direct top-down modulation of neuronal firing rates underlying selective visual attentional modulation.In this issue of , Spyropoulos et al. report direct top-down modulation of neuronal firing rates underlying selective visual attentional modulation.

Lessons on targeting family mental health and improving outcomes for children of parents with a mental illness 1 August 2024
Nature Mental Health, Published online: 01 August 2024; doi:10.1038/s44220-024-00285-3Children of parents with a mental illness are at risk of adverse mental health outcomes. This Perspective discusses lessons learned from the European projects targeting family mental health and, on the basis of identified problems and barriers, provides recommendations to guide the development of future projects and […]
Elena Toffol
From diagnostic conformity to co-narration of self-insight in mental health care 30 July 2024
Nature Mental Health, Published online: 30 July 2024; doi:10.1038/s44220-024-00284-4This Perspective seeks to identify the limitations of the ‘clinical insight’ construct discussing an alternative narrative approach for individuals with psychosis.
N. J. Ermers
Publisher Correction: Neuroanatomical dimensions in medication-free individuals with major depressive disorder and treatment response to SSRI antidepressant medications or placebo 26 July 2024
Nature Mental Health, Published online: 26 July 2024; doi:10.1038/s44220-024-00301-6Publisher Correction: Neuroanatomical dimensions in medication-free individuals with major depressive disorder and treatment response to SSRI antidepressant medications or placebo
Cynthia H. Y. Fu

The diagnosis of ASD with MRI: a systematic review and meta-analysis 2 August 2024
Translational Psychiatry, Published online: 02 August 2024; doi:10.1038/s41398-024-03024-5The diagnosis of ASD with MRI: a systematic review and meta-analysis
Sjir J. C. Schielen
The role of functional emotion circuits in distinct dimensions of psychopathology in youth 2 August 2024
Translational Psychiatry, Published online: 02 August 2024; doi:10.1038/s41398-024-03036-1The role of functional emotion circuits in distinct dimensions of psychopathology in youth
Valerie Karl
Accuracy and transportability of machine learning models for adolescent suicide prediction with longitudinal clinical records 31 July 2024
Translational Psychiatry, Published online: 31 July 2024; doi:10.1038/s41398-024-03034-3Accuracy and transportability of machine learning models for adolescent suicide prediction with longitudinal clinical records
Chengxi Zang

WFP News Section 21 May 2024
Oxytocin-Augmented Modular-Based Group Intervention for Loneliness: A Proof-Of-Concept Randomized Controlled Trial 16 May 2024
AbstractIntroduction: Loneliness poses a significant health problem and existing psychological interventions have shown only limited positive effects on loneliness. Based on preliminary evidence for impaired oxytocin signaling in trait-like loneliness, the current proof-of-concept study used a randomized, double-blind, placebo-controlled design to probe intranasal oxytocin (OT) as an adjunct to a short-term modular-based group intervention for […]
Efficacy of an Internet- and Mobile-Based Intervention for Subclinical Anxiety and Depression (ICare Prevent) with Two Guidance Formats: Results from a Three-Armed Randomized Controlled Trial 30 April 2024
AbstractIntroduction: Limited research exists on intervention efficacy for comorbid subclinical anxiety and depressive disorders, despite their common co-occurrence. Internet- and mobile-based interventions (IMIs) are promising to reach individuals facing subclinical symptoms. Objective: This study aimed to evaluate the efficacy of a transdiagnostic and self-tailored IMI in reducing subclinical anxiety and depressive symptom severity with either […]

Implications for driving based on the risk of seizures after ischaemic stroke 2 August 2024
BackgroundIn addition to other stroke-related deficits, the risk of seizures may impact driving ability after stroke.MethodsWe analysed data from a multicentre international cohort, including 4452 adults with acute ischaemic stroke and no prior seizures. We calculated the Chance of Occurrence of Seizure in the next Year (COSY) according to the SeLECT2.0 prognostic model. We considered […]
Schubert, K. M., Bicciato, G., Sinka, L., Abraira, L., Santamarina, E., Alvarez-Sabin, J., Ferreira-Atuesta, C., Katan, M., Scherrer, N., Terziev, R., Döhler, N., Erdelyi-Canavese, B., Felbecker, A., Siebel, P., Winklehner, M., von Oertzen, T. J., Wagner, J. N., Gigli, G. L., Nilo, A., Janes, F., Merlino, G., Valente, M., Zafra-Sierra, M. P., Mayor-Romero, L. C., Conrad, J., Evers, S., Lochner, P., Roell, F., Brigo, F., Bentes, C., Peralta, R., Pinho e Melo, T., Keezer, M. R., Duncan, J. S., Sander, J. W., Tettenborn, B., Koepp, M., Galovic, M.
Cognition in patients with myelin oligodendrocyte glycoprotein antibody-associated disease: a prospective, longitudinal, multicentre study of 113 patients (CogniMOG-Study) 31 July 2024
BackgroundData on cognition in patients with myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD) are limited to studies with small sample sizes. Therefore, we aimed to analyse the extent, characteristics and the longitudinal course of potential cognitive deficits in patients with MOGAD.MethodsThe CogniMOG-Study is a prospective, longitudinal and multicentre observational study of 113 patients with MOGAD. Individual […]
Passoke, S., Stern, C., Häussler, V., Kümpfel, T., Havla, J., Engels, D., Jarius, S., Wildemann, B., Korporal-Kuhnke, M., Senel, M., Stellmann, J.-P., Warnke, C., Grothe, M., Schülke, R., Gingele, S., Kretschmer, J. R., Klotz, L., Walter, A., Then Bergh, F., Aktas, O., Ringelstein, M., Ayzenberg, I., Schwake, C., Kleiter, I., Sperber, P. S., Rust, R., Schindler, P., Bellmann-Strobl, J., Paul, F., Kopp, B., Trebst, C., Hümmert, M. W., on behalf of the Neuromyelitis Optica Study Group (NEMOS), The Neuromyelitis Optica Study Group (NEMOS), Albrecht, Angstwurm, Asseyer, Bayas, Bednarz, Behnke, Berthele, Bittner, Bütow, Buttmann, Dawin, Dersch, Duchow, Etgen, Finke, Fischer, Förster, Fousse, Frank, Freitag, Gahlen, Gass, Gehrig, Geis, Giglhuber, Goereci, Gold, Galvao Ribeiro Gomes, Graf, Groppa, Gutbrod, Guthke, Haarmann, Hastermann, Hellwig, Hemmer, Herfurth, Herwerth, Hoffmann, Hoffmann, Oy, Husseini, Ingenhoven, Junghans, Kaste, Kern, Kern, Kermer, Kleinschnitz, Köhler, Körbel, Kowarik, Krämer, Krumbholz, Kunzmann, Kurka, Ladopoulos, Landwehr, Langel, Lauenstein, Laurent, Lee, Lehrieder, Leypoldt, Liebetrau, Lindenblatt, Linker, Lohmann, Lüdemann, Luessi, Maiworm, Marziniak, Mayer, Meister, Melms, Mering, Metz, Meuth, Naumann, Nenkov, Neuhaus, Neziraj, Niederschweiberer, Niehaus, Oertel, Otto, Pache, Pakeerathan, Paryjas, Pawlitzki, Pepping, Pfeuffer, Pompsch, Pretzsch, Proebstel, Protopapa, Puhlmann, Pul, Rauer, Rehfeldt, Retzlaff, Riedlinger, Rommer, Rostasy, Rothhammer, Rückriem, Ruprecht, Ruschil, Saggau, Schraad, Schwab, Schwarz, Seipelt, Sieb, Soloroza, Sommer, Stefanou, Steinbrecher, Stephanik, Steuerwald, Stoppe, Stürner, Süsse, Tarampanis, Tauber, Tkachenko, Tsaktanis, Tumani, Wallwitz, Walz, Wandinger, Weber, Weise, Wickel, Wiendl, Winkelmann, Wohlrab, Yalachkov, Zettl, Ziemann, Zipp
White matter abnormalities in healthy E200K carriers may serve as an early biomarker for genetic Creutzfeldt-Jakob disease (gCJD) 31 July 2024
BackgroundMRI is an important tool for disease diagnosis of Creutzfeldt-Jakob disease (CJD), yet its role in identifying preclinical stages of disease remains unclear. Here, we explored subtle white matter (WM) alterations in genetic CJD (gCJD) patients and in asymptomatic E200K mutation carriers using MRI, depending on total tau protein (t-tau) levels in CSF.MethodsSix symptomatic gCJD […]
Omer, N., Droby, A., Silbak, R., Trablus, N., Bar David, A., Shiner, T., Alcalay, Y., Alcalay, R., Nathan, T., Thaler, A., Mirelman, A., Gana Weisz, M., Goldstein, O., Glinka, T., Orr-Urtreger, A., Giladi, N., Bregman, N.

Mendelian randomization: causal inference leveraging genetic data 19 April 2024
Mendelian randomization (MR) leverages genetic information to examine the causal relationship between phenotypes allowing for the presence of unmeasured confounders. MR has been widely applied to unresolved questions in epidemiology, making use of summary statistics from genome-wide association studies on an increasing number of human traits. However, an understanding of essential concepts is necessary for […]
Chen, Lane G.
Interventions targeting social determinants of mental disorders and the Sustainable Development Goals: a systematic review of reviews 25 March 2024
Globally, mental disorders account for almost 20% of disease burden and there is growing evidence that mental disorders are socially determined. Tackling the United Nations Sustainable Development Goals (UN SDGs), which address social determinants of mental disorders, may be an effective way to reduce the global burden of mental disorders. We conducted a systematic review […]
Oswald, Tassia Kate
Do metacognitive therapies for schizophrenia-spectrum disorders work? A meta-analytic investigation 21 March 2024
Recent reviews and meta-analyses of metacognitive therapy for schizophrenia-spectrum disorder (SSD) have included uncontrolled studies, single-session interventions, and/or analyses limited to a single form of metacognitive therapy. We sought to evaluate the efficacy of metacognitive therapies more broadly based on controlled trials (CT) of sustained treatments. We conducted a pre-registered meta-analysis of controlled trials that […]
Melville, Grace

Electroconvulsive therapy in the maintenance phase of psychotic unipolar depression 2 August 2024
Acta Psychiatrica Scandinavica, Volume 150, Issue 3, Page 148-159, September 2024.
Ahmed Al‐Wandi, Mikael Landén, Axel Nordenskjöld
Early specialised treatment for bipolar disorder: Long‐term follow‐up from the early intervention in affective disorders (EIA) randomised controlled trial 2 August 2024
Acta Psychiatrica Scandinavica, Volume 150, Issue 3, Page 138-147, September 2024.
Klaus Munkholm, Lars Vedel Kessing
Drug survival and risk factors for ADHD medication discontinuation in adults: A Danish Nationwide Registry‐based cohort study 2 August 2024
Acta Psychiatrica Scandinavica, Volume 150, Issue 3, Page 160-173, September 2024.
Pelle Lau Ishøy, Kim Berg Engersgaard Johannessen, Tine Houmann, Eline Levin, Per Hove Thomsen

Age and gender differences in motives for z‐drug misuse: Findings from the 2015 to 2019 NSDUH survey 3 August 2024
The American Journal on Addictions, EarlyView.
Robyn A. Ellis, Emma Trapani, R. Kathryn McHugh
State inequities: Gaps in planned treatment for criminal legal referrals with opioid use disorder across two decades of US treatment admissions 3 August 2024
The American Journal on Addictions, EarlyView.
Nicholas L. Bormann, Andrea N. Weber, Tyler S. Oesterle, Benjamin Miskle, Alison C. Lynch, Stephan Arndt
A detox dilemma beyond benzodiazepines; clonidine's quandary in alcohol withdrawal management 3 August 2024
The American Journal on Addictions, EarlyView.
Matthew Johnson, Danielle Cosentino, Brian Fuehrlein

A role for Shugoshin in human cilia?
We have recently described a novel role for the conserved centromeric/kinetochore protein and cohesin protector, Shugoshin, in cilia of C. elegans. Worms are unusual in that the sole Shugoshin protein ( SGO-1 ) is dispensable for chromosome segregation but required for cilia function in fully differentiated sensory neurons. Depletion of sgo-1 leads to an array […]
sut-2 loss of function mutants protect against tau-driven shortened lifespan and hyperactive pharyngeal pumping in a C. elegans model of tau toxicity.
Expression of human tau in C. elegans neurons causes progressive, age-associated loss of motor coordination, selective neurodegeneration, and shortened lifespan. Loss of function (LOF) mutations in the conserved gene sut-2 protects against progressive motor uncoordination and neurodegeneration in models of tauopathy. To determine whether sut-2 LOF also protects against shortened lifespan of tau transgenic C. […]
Evidence Based Clinical Analytics Supporting the Genetic Addiction Risk Severity (GARS) Assessment to Early Identify Probands in Preaddiction.
No abstract supplied.

Evolving Perspectives on Wellness and Stress
Renewing the Teaching of Clinical Reasoning in Psychiatry: An Opportunity for Advancing Mental Health Training and Care
Assaults and Microaggressions Against Psychiatric Residents: Findings from a US Survey
Psychiatric physicians may experience higher rates of assault than those in other fields. For many reasons, residents may be especially vulnerable. This study updates rates of assaults among US psychiatry residents as well as the reporting rates and emotional effects of these incidents. Little data exists to examine rates of microaggressions against psychiatry residents.A cross-sectional […]

Illness Anxiety Disorder: A Review of the Current Research and Future Directions
We review recent evidence on Illness Anxiety Disorder (IAD), including risk factors and precipitants, diagnostic classification, clinical characteristics of the disorder, and assessment and treatment in both children and adults.IAD places a substantial burden on both individuals and society. Despite its impact, understanding of the disorder is lacking and debates remain about whether IAD should […]
Eating Disorders in Sexual and Gender Minority Adolescents
To consolidate recent literature addressing eating disorders and disordered eating behaviors among sexual and gender minority (SGM) adolescents, including but not limited to lesbian, gay, bisexual, transgender, and queer (LGBTQ) adolescents.Sexual and gender minority adolescents are at heightened vulnerability to eating disorders and disordered eating behaviors compared to their cisgender and heterosexual peers, potentially due […]
Recent Advances in Cognitive-Behavioural Therapy for Eating Disorders (CBT-ED)
Eating disorders require more effective therapies than are currently available. While cognitive behavioural therapy for eating disorders (CBT-ED) has the most evidence to support its effectiveness, it requires substantial improvement in order to enhance its reach and outcomes, and to reduce relapse rates. Recent years have seen a number of noteworthy developments in CBT-ED, which […]

Editorial introductions
No abstract available
journals.lww.com
Sex and gender differences in cancer in individuals with severe mental disorders
Purpose of review Although cancer incidence is similar between individuals with severe mental disorders (SMD) and the general population (GP), survival rates are lower, particularly in those with schizophrenia. While the scientific and medical communities acknowledge sex differences in cancer mechanisms, including risk factors and cancer types, less is known about sex and gender disparities […]
Bajić, Žarko; Vuk-Pisk, Sandra; Filipčić, Igor; Šimunović Filipčić, Ivona
The role of human involvement and support in digital mental health interventions for people with schizophrenia spectrum disorders: a critical review
Purpose of review Schizophrenia spectrum disorders (SDD) are characterized by a complex array of psychosis symptoms, and typically require ongoing and long-term support, including pharmacological and nonpharmacological management. Digital mental health interventions (DMHIs) have been suggested as a novel therapeutic approach to enable low-cost, scalable improvements in quality of care for adults living with SSD. […]
Arnautovska, Urska; Milton, Alyssa; Trott, Mike; Soole, Rebecca; Siskind, Dan

Anhedonia is associated with overgeneralization of conditioned fear during late adolescence and early adulthood
Pavlovian fear paradigms involve learning to associate cues with threat or safety. Aberrances in Pavlovian fear learning correlate with psychopathology, especially anxiety disorders. This study evaluated symptom dimensions of anxiety and depression in relation to Pavlovian fear acquisition and generalization.256 participants (70.31 % female) completed a Pavlovian fear acquisition and generalization paradigm at ages 18–19 and […]
Interventions to reduce adult state anxiety, dental trait anxiety, and dental phobia: A systematic review and meta-analyses of randomized controlled trials
For alleviating state anxiety (distress) during oral surgery, hypnosis and conscious sedation with benzodiazepines showed small effects.Psychotherapy for state anxiety is inconclusive; virtual reality distraction, music, aromatherapy, an information video, and acupuncture lack evidence.For the treatment of chronic dental (trait) anxiety, the use of Cognitive Behavioral Therapy (CBT) showed a moderate reducing effect.For dental phobia, […]
Testing predictions from the memory and identity theory of ICD-11 complex posttraumatic stress disorder: Measurement development and initial findings
This is the first empirical assessment of predictions for the M&I theory of ICD-11 Complex PTSD.The Experiences of Traumatic Memories and Traumatic Identity Questionnaire have excellent psychometric properties.8 of 9 model-implied relations were supported.Trauma memories were strongly associated with all CPTSD symptom clusters.Identities related to feeling vulnerable, worthless, and disconnected from others were related to […]

Characteristics of children with a psychiatric disorder in 1999, 2004 and 2017: an analysis of the national child mental health surveys of England 24 July 2024
Journal of Child Psychology and Psychiatry, EarlyView.
Jessica M. Armitage, Tamsin Newlove‐Delgado, Tamsin Ford, Sally McManus, Stephan Collishaw
Issue Information 23 July 2024
Journal of Child Psychology and Psychiatry, Volume 65, Issue 8, Page i-iv, August 2024.
Editorial: For better or for worse? Intended and unintended consequences of science communication 23 July 2024
Journal of Child Psychology and Psychiatry, Volume 65, Issue 8, Page 995-997, August 2024.
Alice M. Gregory, Fatos Selita, Yulia Kovas

Prevalence and correlates of insomnia and fatigue in patients with type 2 diabetes in Jordan 26 July 2024
The International Journal of Psychiatry in Medicine, Ahead of Print. Objective: The present study examined the prevalence and correlates of insomnia and fatigue in patients with type-2 diabetes in Jordan.Methods: This was a cross-sectional online study involving a convenience sample of 390 patients with type-2 diabetes. Insomnia was assessed by the Insomnia-Severity Index (ISI-A) and […]
Salam Shannag
The association between lipid accumulation products and depression in U.S. adults: A cross-sectional study from NHANES 2005-2018 24 July 2024
The International Journal of Psychiatry in Medicine, Ahead of Print. ObjectiveTo investigate the potential correlation between lipid accumulation products (LAP) and depression in adults in the United States.MethodsWe analyzed data from 13,051 participants from the NHANES 2005-2018 cycle. The LAP index was calculated using the waist circumference (WC) and serum triglyceride (TG) levels, which reflect […]
Mengyao Dai
Anxiety symptoms and risk factors in patients with SARS-cov-2 omicron variant in shanghai, China 23 July 2024
The International Journal of Psychiatry in Medicine, Ahead of Print. ObjectivesThe psychological effects of the COVID-19 pandemic may include anxiety. However, the association between demographic and physiological factors in COVID-19 associated anxiety symptoms is poorly understood. Therefore, the present cross-sectional study was conducted to examine anxiety symptoms and associated factors among patients with the SARS-CoV-2 […]
Qing Chen

Global, regional, and national time trends in incidence for depressive disorders, from 1990 to 2019: an age-period-cohort analysis for the GBD 2019 2 August 2024
Even with advances in primary health care, depressive disorders remain a major global public health problem. We conducted an in-depth analysis of global, regional and national trends in depressive disorders in...
Yuhang Wu, Luying Fan, Fan Xia, Yunzhe Zhou, Haiyan Wang, Lijuan Feng, Shudong Xie, Wendi Xu, Zhiqin Xie, Jing He, Dan Liu, Sui He, Yuting Xu, Jing Deng, Tingting Wang and Lizhang Chen
Predictors of continuation for asenapine from real-world data in patients with schizophrenia 2 August 2024
The continuation rates of pharmacotherapy in schizophrenia exhibit variability, a phenomenon influenced by the specific antipsychotic agent prescribed and patient-related factors such as age and duration of il...
Yoshiteru Takekita, Shuichi Hiraoka, Yasuhiro Iwama, Daisuke Matsui, Nobuatsu Aoki, Haruhiko Ogata, Toshiya Funatsuki, Toshiyuki Shimizu, Yuji Murase, Yutaro Shimamoto, Yosuke Koshikawa and Masaki Kato
Brain-derived neurotrophic factor and C-reactive protein (CRP) biomarkers in suicide attempter and non-attempter major depression disorder (MDD) patients 22 July 2024
In the available literature, levels of BDNF and CRP have been reported to correlate with suicide in depressive patients but there are inconsistencies in the results. We aimed to evaluate and compare BDNF and C...
Seyed Hassan Saadat, Mohammad Javanbakht and Shima Shahyad

Development and validation of the Gender Identity and Expression Microaggressions in Therapy Scale (GIEMTS). 18 April 2024
Developing affirming interventions for transgender and nonbinary (TNB) therapy clients requires understanding their experiences with microaggressions in psychotherapy, yet no self-report measure of anti-TNB microaggressions in this context exists. Moreover, few studies have tested the associations between anti-TNB microaggressions and therapy processes. To better address the burden of unmet mental health care needs among TNB […]
The evolution of feedback: Toward a multicultural orientation. 18 April 2024
There have been great strides in psychology regarding diversity, equity, inclusion, and multicultural competence, but a need remains to translate these values into actionable practices in psychotherapy. While the case has been made that measurement-based care is an evidence-based intervention that improves outcomes and reduces dropouts (de Jong et al., 2021) and recently that it […]
Beyond the dyad: Broadening the APA supervision guidelines to include group supervision. 28 March 2024
Group supervision is an extensively used format across many training agencies, yet it has been largely disregarded in theory and research within the supervision literature. In fact, the Guidelines for Clinical Supervision in Health Service Psychology (American Psychological Association, 2015a) mentions group supervision only one time, despite the fact that supervision within a group context […]

A Family-Based Intervention for Early Elementary Students With Reading and Behavioral Difficulties: A Pilot Study 2 August 2024
Journal of Learning Disabilities, Ahead of Print. We created and tested a family-based intervention with families of children in Grades 1 and 2 with reading and behavioral difficulties to investigate its impact on text comprehension. Developed with input from parents, reading experts, and behavior specialists, Family-RISE (Reading Intervention with Supports for Engagement) integrates evidence-based practices […]
Garrett J. Roberts
Assessing Beliefs About Intrinsic and Extrinsic Determinants of SLD: Evaluating the Factor Structure of a Novel Instrument 26 July 2024
Journal of Learning Disabilities, Ahead of Print. Schools conduct comprehensive psychoeducational evaluations to identify students with specific learning disabilities (SLDs) and determine whether they qualify for special education services. This decision-making process is complex and research has documented many factors influencing SLD identification decisions. One such factor may be decision-makers’ beliefs about the underlying causes […]
Courtenay A. Barrett
Do Mathematics and Reading Skills Impact Student Science Outcomes? 26 July 2024
Journal of Learning Disabilities, Ahead of Print. Establishing validated science programs for students with or at risk for learning disabilities requires testing treatment effects and exploring differential response patterns. This study explored whether students’ initial mathematics and reading skills influenced their treatment response to a whole-class, second-grade science program called Scientific Explorers (Sci2). The original […]
Christian T. Doabler

Bridging the digital divide for individuals with intellectual disabilities: Implications for well‐being and inclusion 25 July 2024
British Journal of Learning Disabilities, EarlyView.
Esther Murphy, Orla Shiels, Sara Fiori, Darren McCausland, Helena Bergström, Raphael Koster, Hanna Noorlandt, Ida Korfage, Eva Flygare Wallén
The role of lived experience eye care champions in improving awareness and access to eye care services for people with learning disabilities and/or autism 22 July 2024
British Journal of Learning Disabilities, Volume 52, Issue 3, Page 489-499, September 2024.
Marek Karas, Donna O'Brien, Lance Campbell, Rebecca Lunness, Joanne Kennedy, Grace McGill, Stephen Kill, Lisa Donaldson
Evaluation of a co‐designed Health Check‐in for adults with intellectual and developmental disabilities and family caregivers to support pandemic recovery 22 July 2024
British Journal of Learning Disabilities, Volume 52, Issue 3, Page 512-523, September 2024.
Yona Lunsky, Tiziana Volpe, Laura St. John, Anupam Thakur, Johanna Lake, the H‐CARDD COVID Program Team

Police officers’ perception of mentally disordered people: a national survey in Japan 2 August 2024
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Akihiro Shiina Tomihisa Niitsu Aika Tomoto Masaomi Iyo Eiji Shimizu Chiyo Fujii a Center for Forensic Mental Health, Chiba University, Chiba-shi, Chiba, Japanb Department of Psychiatry, Chiba University Graduate School of Medicine, Chiba-shi, Chiba, Japanc Department of Cognitive Behavioural Physiology, Chiba University Graduate School of Medicine, Chiba-shi, Chiba, Japand National Institute of Mental Health, National Center of Neurology and Psychiatry, Kodaira-shi, Tokyo, Japan
“This place does a lot more than produce milk”: a reflexive thematic analysis of staff experiences of supporting prison dairy workers 1 August 2024
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Libby Payne Mary McMurran Clare Glennan Jenny Mercer Department of Applied Psychology, Cardiff Metropolitan University, Llandaff, Cardiff, Wales, UK
Correction 31 July 2024
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Therapeutic and non-therapeutic practices in the child justice system in Kenya: A therapeutic jurisprudence perspective
Child justice systems are specialized jurisdictions set up for the purpose of providing justice related services to children. In an effort to resolve many of the systemic injustices expereinced by justice involved children, Kenya recently legislated the Children Act 2022. This new law is viewed as a paradigm shift from previous children acts as it […]
Forensic criteria, clinical and theoretical issues of the indication of court-ordered treatment: A comparative survey among experts in forensic psychiatry and sentencing judges in France
Following the French law n° 98–468 of 17 June 1998 relative to the prevention of sexual offenses and the protection of minors, social and judicial follow-up and court-ordered treatment were introduced with the aim of reinforcing the prevention of recidivism. Court-ordered treatment is one of the possible obligatory measures provided for by social and judicial […]
Editorial Board

Changing environments to promote safety in libraries
The purpose of this article is to investigate how changes in the environment of a library affect the safety conditions of both visitors and staff. Using principles of Crime Prevention Through Environmental Design, crime and incidents of public disturbance from 2017 to 2020 from libraries in Stockholm, Sweden, are analyzed and later mapped using 3D […]
Revisiting the tautology problem in rational choice theory: What it is and how to move forward theoretically and empirically
Criminological rational choice theory is blighted by tautology—that if a crime occurs, then by definition the benefits must exceed the costs. The current analysis details the nature of this tautology as well as its theoretical and philosophical implications concerning the circumstances under which offenders make rational (thoughtful and reflective) or irrational (habitual, intuitive, or instinctual) […]
Experiences of fatherhood in prison: A thematic analysis of differences between fathers in a family approach programme and a comparison group
Various programmes have been implemented in prisons to strengthen parental involvement and parent–child relationships during imprisonment. In-depth insights into such programmes are limited. This qualitative study compared the experiences of two groups of imprisoned fathers in the Netherlands: fathers who participated in a family approach programme ( = 10) and fathers in a comparison group ( = 29). Based […]

“I just thought maybe this is [the] way of doing things”: Exploring lesbian-, gay-, and bisexual-specific intimate partner violence in Norway. 23 May 2024
Objective: Intimate partner violence (IPV) in lesbian, gay, and bisexual (LGB) relationships seems to be at least as high as in heterosexual relationships. However, there are uncertainties regarding how IPV is more specifically experienced in LGB relationships. We explore how LGB individuals exposed to IPV make sense of the potentially more specific ways in which […]
When childhood states become adult traits: Trait anxiety and anger as mediators linking childhood maltreatment to marital outcomes in midlife adults. 23 May 2024
Objective: Childhood maltreatment has been consistently linked to problematic marriages. The pathways, however, linking childhood maltreatment to marital problems over time remain understudied. The present study examined trait anger and trait anxiety as possible mediators linking childhood maltreatment to marital quality, support, and strain over a 9 year period. It was expected that both trait […]
Profiles of service-engaged intimate partner violence survivors: Considerations for service delivery and continuation. 16 May 2024
Objective: This study examined factors considered to influence service engagement among intimate partner violence (IPV) survivors. Specifically, it (a) investigated patterns of cultural beliefs, stigma related to attitudes about seeking formal help, and IPV experiences among service-engaged survivors and (b) explored their association with sociodemographic characteristics. Method: Mixture modeling was conducted using the Testing and […]

The association between alcohol retail access and health care visits attributable to alcohol for individuals with and without a history of alcohol‐related health‐care use 2 August 2024
Addiction, Volume 119, Issue 9, Page 1554-1563, September 2024.
Daniel T. Myran, Erik Friesen, Robert Talarico, Adrienne Gaudreault, Monica Taljaard, Erin Hobin, Brendan T. Smith, Naomi Schwartz, Norman Giesbrecht, Jean‐François Crépault, Peter Tanuseputro, Douglas G. Manuel
A retrospective study of the characteristics and toxicology of cases of lysergic acid diethylamide (LSD)‐ and psilocybin‐related death in Australia 2 August 2024
Addiction, Volume 119, Issue 9, Page 1564-1571, September 2024.
Shane Darke, Johan Duflou, Amy Peacock, Michael Farrell, Wayne Hall, Julia Lappin
Increased cancer incidence and mortality among people with opioid use‐related disorders: A nation‐wide cohort study 2 August 2024
Addiction, Volume 119, Issue 9, Page 1575-1584, September 2024.
Emil Kostovski, Aleksi Hamina, Vidar Hjellvik, Thomas Clausen, Svetlana Skurtveit

A feasibility evaluation of a peer support intervention for social participation in China 2 August 2024
This study aims to report on the feasibility, acceptability and outcomes of a peer support program designed to promote social participation for adults with serious mental illness (SMI) in China. The authors used a community-based participatory research approach to adapt and test a six-month, culturally responsive peer program with 68 participants. Peer supporters were trained […]
Xiyuan Chen
A community center to mobilize public policies and human rights in mental health: “the door is always open” 30 July 2024
This study aims to describe the perceptions of some participants from a community mental health center in the Department of Chocó, Colombia. A case study with a qualitative approach was carried out in 2023. Focus groups were conducted with mental health leaders and members of a community mental health center. The data were analyzed using […]
Felipe Agudelo-Hernández
Editorial: International perspectives in public mental health 5 June 2024
Editorial: International perspectives in public mental health
Neil Quinn

The notion of excessive childhood restlessness in Spain at the beginning of the twentieth century 27 July 2024
History of Psychiatry, Ahead of Print. This study delves into the historical documentation from 1900 to 1936 by Spanish doctors and educators concerning children’s hyperactivity. By focusing on medical perspectives of the time, we aim to explore the conceptualisation of childhood phenomenology within the context of significant international literature of that era. The publications of […]
Joana Escamilla Lerner
Empathy or sympathy: a necessary distinction? 23 July 2024
History of Psychiatry, Ahead of Print. As a deeply hybrid discipline, psychiatry demands research that tackles the concepts constituting it and its objects. This is an essential prerequisite to empirical studies, the validity of which are directly dependent on a clear understanding of the underlying concepts. Empathy and sympathy are concepts used variably and inconsistently […]
Ivana S Marková
A history of mental illness among women in the Straits Settlements in the nineteenth century 15 June 2024
History of Psychiatry, Ahead of Print. The Straits Settlements, a collective colony under the administration of British Malaya, was a very unhealthy area in the early years of the nineteenth century. One of the most common sicknesses was mental illness, which could not be cured by medicines. The number of women suffering from mental illness […]
Haszira Muhamad Yusof

Inequitable access to mental healthcare for socially excluded adolescents 31 July 2024
International Journal of Social Psychiatry, Ahead of Print. Background:Adolescence is a critical period for mental health and social exclusion, a key social determinant of mental health. Early intervention approaches are key to mitigating the impact of mental ill-health during adolescence, however social exclusion can create additional barriers to accessing care.Aim:We aimed to better understand help-seeking […]
Kate Filia
Others, othering, otherism and social psychiatry 31 July 2024
International Journal of Social Psychiatry, Ahead of Print.
Dinesh Bhugra
Influence of prior contact with community mental health services on first inpatient psychiatric admission for ethnic minorities: Findings from the NOMIAC study 31 July 2024
International Journal of Social Psychiatry, Ahead of Print. Background:Research has extensively documented inequalities in inpatient psychiatric care provided to people of minoritized ethnic groups. Nonetheless, the role of their previous engagement with community mental health care has been little studied.Aims:We aimed at exploring whether previous clinical care can influence key domains of subsequent psychiatric inpatient […]
Giuseppe Carrà

An Assessment of Contemporary Methods and Data-Enabled Approaches for Early Cataract Detection [version 2; peer review: 1 approved with reservations] 2 August 2024
Background: Cataracts are common causes of visual impairment. Preventing blindness requires an early and accurate diagnosis. This review examines current cataract diagnosis strategies, explores data-driven machine learning algorithms for early detection, investigates the use of artificial intelligence (AI) approaches, assesses improvements in cataract detection accuracy, identifies research gaps, and provides recommendations for future studies. Methods: […]
Chris Muchibwa
Case Report: Rare case of Cutaneous Metastasis of Follicular Thyroid Carcinoma. [version 1; peer review: awaiting peer review] 2 August 2024
Follicular thyroid cancer (FTC) is the second most common differentiated thyroid cancer, accounting for approximately 10–15% of all thyroid cancers. Skin metastasis is rare, and only 30 cases have been documented as of 1997. Here, we present a rare case of cutaneous metastasis of follicular thyroid carcinoma with clinical, dermoscopic, and histopathological findings as well […]
Mohammed Nasser Al-Abdulla
Case Report: Activated B-cell-diffuse large B-cell lymphoma [version 3; peer review: 2 approved, 2 approved with reservations] 2 August 2024
Lymphomas of the oral and oropharyngeal regions are rather uncommon, and diagnosis can be challenging and confusing due to the multiple histological subgroups. Lymphomas are the third most common type of tumor in the head and neck region and are brought on by the lymphoreticular system. The two forms of lymphoma are Hodgkin’s lymphoma and […]
Padmashri Kalmegh

The Promise of 'Magic Mushrooms' for Mental Health Is Real 3 August 2024
(MedPage Today) -- Looking for an election-year healthcare issue that could bring the two major political parties together? Think there is no such thing? Think again. A public opinion survey conducted last summer by the University of California...
Midlife Blood Biomarkers Predict Late-Life Dementia 2 August 2024
(MedPage Today) -- PHILADELPHIA -- Blood biomarkers specific to Alzheimer's disease -- specifically, amyloid-beta 42/40 ratios and measures of phosphorylated tau 181 (p-tau181) -- had a relationship with subsequent dementia that started in...
Where Harris' VP Options Stand on Healthcare 1 August 2024
(MedPage Today) -- Democratic presidential candidate Kamala Harris is said to be announcing her vice presidential candidate imminently, and major news organizations have homed in on a few top candidates: Pennsylvania Gov. Josh Shapiro, Arizona...

Higher omega-3 levels linked to lower risk of depression, study finds - PsyPost 3 August 2024
These findings were published in the journal Translational Psychiatry. ... Psychiatric Genomics Consortium (PGC) genome-wide association studies ...
IUP names associate dean of proposed osteopathic college | News | cnhinews.com 3 August 2024
Smith is an experienced psychiatrist and doctor of osteopathic medicine. ... Psychiatry · Leadership · Clinical Clerkship · Education · Clinical ...
Researchers say discovery points to possible autism cause in children - AZERTAC 3 August 2024
Their study, published on July 23 in the journal Psychiatry ... psychiatry and psychology professor at Yale University, told Newsweek more research is ...

FDA Approves First Engineered Cell Therapy for a Solid Tumor 2 August 2024
The afami-cel approval marks the first for an engineered T-cell receptor therapy targeting a solid tumor; the therapy was approved for adults with unresectable or metastatic synovial sarcoma. Medscape Medical News
An Effective Nondrug Approach to Improve Sleep in Dementia 2 August 2024
A multicomponent nonpharmaceutical intervention improves sleep in people with dementia living at home, early results from a new phase 3 randomized trial show. Medscape Medical News
How Do Oncologists Differ in End-of-Life Therapy? 2 August 2024
Researchers estimate oncologists' rates of providing cancer therapy in the last 30 days of life. Medscape Medical News

More access to breastfeeding support could save 820,000 young lives annually, UN agencies say 31 July 2024
The heads of the UN Children’s Fund (UNICEF) and the World Health Organization (WHO) have called for greater access to breastfeeding support to both reduce health inequity and ensure mothers and babies can survive and thrive.
Healthcare in Sudan ‘hanging by a thread,’ warns UN agency 29 July 2024
The UN World Health Organization (WHO) on Monday strongly denounced the increasing attacks on healthcare facilities in Sudan, reporting over 20 such incidents in the last two months.
WHO to send one million polio vaccines to Gaza to protect children 26 July 2024
The UN health agency said on Friday that it is sending more than a million polio vaccines to Gaza after the discovery of the highly infectious disease in sewage samples.

Strength in numbers – how monitoring breastfeeding policies and programmes creates accountability and empowers change 1 August 2024
Among the number of events during World Breastfeeding Week, on the 6th of August, WHO, UNICEF, and Global Breastfeeding Collective will be hosting the webinar
who.int
Children in Gaza are now at risk of polio as well as bombs – we need a ceasefire now 1 August 2024
The polio virus was detected in wastewater samples in Gaza last week, an alarming yet unsurprising development given the dismantled state of the territory’s health systems after nine relentless months of war.
who.int
Fact sheets 30 July 2024
who.int

WHO and United Arab Emirates evacuate 85 patients from Gaza 30 July 2024
30 July 2024 Jerusalem, Cairo, Geneva Today, 85 sick and severely injured patients from Gaza were evacuated to Abu Dhabi, United Arab Emirates (UAE), for specialized care. This extremely complex joint evacuation was supported by the the World Health Organization (WHO) in partnership with the Government of the UAE and other partners. This is the […]
World Hepatitis Day 2024: It’s Time for Action 28 July 2024
28 July 2024, Cairo, Egypt – “It’s Time for Action”, urges WHO’s campaign to mark World Hepatitis Day 2024. In the Eastern Mediterranean Region and globally, WHO is calling on governments and communities to intensify efforts to combat hepatitis, emphasizing the need for urgent action. Fighting hepatitis in the Eastern Mediterranean Region raises both significant […]
Fifteen children from Gaza to receive urgent medical care in Spain 25 July 2024
Cairo, Copenhagen, Geneva, 24 July 2024—Sixteen people from Gaza with complicated medical conditions will arrive in Spain today to receive care there, through an evacuation process involving the World Health Organization (WHO) and multiple partners. Fifteen of them are children, ranging in age from 3 to 17 years old. The mother of one of the […]

Low-Dose Corticosteroids for Adults With Severe Pulmonary Infections 23 July 2024
This Review discusses whether treatment with low-dose corticosteroids may benefit critically ill patients with respiratory infections who have septic shock, acute respiratory distress syndrome, or both.
LGBTQI+ Data Collection in Medicaid to Advance Health Equity 23 July 2024
This Viewpoint explores Centers for Medicare & Medicaid Services guidance on the collection of sexual orientation and gender identity data and how these data could be used to advance health equity for LGBTQI+ people.
Addressing Ableism in Physician Well-Being Planning 23 July 2024
This Viewpoint discusses the importance of physician well-being for optimizing patient care and current efforts to improve physician well-being, describes how structural ableism affects the well-being of physicians with disabilities, and calls for further efforts to address ableism in the health care workforce.

When I use a word . . . . Fictional drugs in dystopian fiction 2 August 2024
Speculative fiction and Walter BesantI have elsewhere defined fictional drugs as non-existent medicines, intended for human use, invented for the purposes of some forms of fiction, usually novels, but also plays or films, including TV dramas. I have discussed some fictional drugs in books written by a wide range of authors: Robert Heinlein, Frank Herbert, […]
Jeffrey K Aronson
Dementia: Almost half of cases could be prevented by tackling 14 risk factors, says commission 2 August 2024
An estimated 45% of dementia cases could be delayed or prevented entirely by tackling 14 risk factors, including high cholesterol and vision loss, a landmark report has concluded.1The 2024 Lancet Commission report, written by 27 of the world’s leading dementia experts, calls for action to tackle these risk factors to begin in childhood and continue […]
Jacqui Wise
An independent panel should evaluate the health of presidential candidates 2 August 2024
President Joe Biden’s 2024 re-election campaign ended on the afternoon of 21 July 2024, not with a bang but a whimper: he posted a brief letter on X (formerly Twitter) announcing he would stand down.1 Even before his disastrous performance in the debate against Donald Trump on 27 June 2024, during which he sometimes seemed […]
Gavin Yamey, Kaveh Hoda

Risk ratios, odds ratios and the risk difference 31 July 2024
The risk ratioScenarioAs a heart surgeon, you regularly perform aortic valve replacement, using a median sternotomy technique. However, you are aware that less-invasive options are available, and you wonder whether these may be as effective and safe as your current practice. After searching the Cochrane Library, you find a systematic review, ‘Limited versus full sternotomy […]
Richardson, R., Kanellopoulou, A., Dwan, K.
Successes, shortcomings and learning opportunities for evidence-based medicine from the COVID-19 pandemic 31 July 2024
The COVID-19 pandemic represents the largest public health crisis of the past century. Faced with a global threat, public health officials, professional societies, clinicians and patients have appropriately sought strategies to prevent SARS-CoV-2 transmission, reduce progression to severe and critical illness, and mitigate short-term and long-term sequelae. Efforts have extended to drug therapies, non-pharmacological interventions […]
Agarwal, A., Guyatt, G.
Simple tool implementing Buchers method for indirect treatment comparisons in meta-analyses 31 July 2024
StandfirstHealthcare practitioners and patients are often required to make choices between two treatment options which may have never been compared directly. When performing standard ‘pairwise’ meta-analysis, it is common to find trials comparing one of two experimental treatments against a common control (standard of care or placebo) but no head-to-head trials. Statistical methods are available […]
Tingle, S. J., Kourounis, G., Liu, F., Wilson, C. H., Richardson, R., Sandercock, J.

Deaths in women’s prisons 31 July 2024
Below is a breakdown of deaths in women’s prisons in England and Wales by calendar year (January-December) since 2013. Figures for the current calendar year and for 2021-2023 may be incomplete as they are based on INQUEST casework and monitoring. The data for previous calendar years are derived from official sources. For data going back […]
Inquest
Deaths in prison 31 July 2024
In this country we do not give a death sentence, but for everyone who has taken their life in prison that is exactly what they got - Mark Saunders, whose son Dean died in HMP & YOI Chelmsford in 2016 Below is a breakdown of deaths in prison in England and Wales by calendar year […]
Inquest
Scott Boughton: Inquest to open into self-inflicted death shortly after contact with Manchester police 30 July 2024
31 July 2024
Inquest