Evidence
![](https://psychiatryai.com/wp-content/uploads/2023/04/psychiatryai_com.webp)
Pediatr Investig. 2024 Mar 18;8(2):108-116. doi: 10.1002/ped4.12422. eCollection 2024 Jun.
ABSTRACT
IMPORTANCE: Critically ill children with pre-existing mental health conditions may have an increased risk of poor health outcomes.
OBJECTIVE: We aimed to evaluate if pre-existing mental health conditions in critically ill pediatric patients would be associated with worse clinical outcomes, compared to children with no documented mental health conditions.
METHODS: This retrospective observational cohort study utilized the TriNetX electronic health record database of critically ill subjects aged 12-18 years. Data were analyzed for demographics, pre-existing conditions, diagnostic, medication, procedural codes, and mortality.
RESULTS: From a dataset of 102 027 critically ill children, we analyzed 1999 subjects (284 [14.2%] with a pre-existing mental health condition and 1715 [85.8%] with no pre-existing mental health condition). Multivariable analysis demonstrated that death within one year was associated with the presence of pre-existing mental health conditions (odds ratio 8.97 [3.48-23.15], P < 0.001), even after controlling for the presence of a complex chronic condition.
INTERPRETATION: The present study demonstrates that the presence of pre-existing mental health conditions was associated with higher odds of death within 1 year after receiving critical care. However, the confidence interval was wide and hence, the findings are inconclusive. Future studies with a larger sample size may be necessary to evaluate the true long-term impact of children with pre-existing mental health conditions who require critical care services.
PMID:38910847 | PMC:PMC11193371 | DOI:10.1002/ped4.12422
![Google](https://www.google.com/images/branding/googlelogo/2x/googlelogo_light_color_92x30dp.png)
![Google Keep](https://www.gstatic.com/images/branding/product/1x/keep_48dp.png)
![Share on Linkedin](https://psychiatryai.com/wp-content/uploads/2023/10/linkedin-logo-png-2048-1.png)
Estimated reading time: 4 minute(s)
Latest: Psychiatryai.com #RAISR4D Evidence
![](/wp-content/uploads/2024/04/bd462cc11bcf0bd0d0d6f1d0f8b7cd04-modified-1.png)
Cool Evidence: Engaging Young People and Students in Real-World Evidence
![](/wp-content/uploads/2024/04/bd462cc11bcf0bd0d0d6f1d0f8b7cd04-modified-1.png)
Real-Time Evidence Search [Psychiatry]
![](/wp-content/uploads/2024/04/pubmed.png)
AI Research
![](/wp-content/uploads/2024/05/Il5nR_nf_400x400-modified-1.png)
Outcomes of critically ill children with pre-existing mental health conditions
![](https://psychiatryai.com/wp-content/uploads/2023/04/psychiatryai_com.webp)
🌐 90 Days
AI Virtual Reality Related Evidence Matrix
Effects of gabapentin on slow-wave sleep period in critically ill adult patients: A randomized controlled trial Association of Delirium with Long-Term Mortality in Critically Ill Patients with COPD Who Survived to Discharge: A Retrospective Cohort Study Clinical Reasoning: A 17-Year-Old Adolescent Boy With New Altered Mental Status in the Pediatric Intensive Care Unit Delirium Associated with COVID-19 in Critically ill Children: An Observational Cohort Study Usefulness of the 4A's test for detecting delirium in critically ill patients: a multicenter prospective observation study Clinical Significance of the Prognostic Nutritional Index in Predicting Delirium among Critically Ill Patients: A Retrospective Cohort Study Clinical Significance of the Prognostic Nutritional Index in Predicting Delirium among Critically Ill Patients: A Retrospective Cohort Study Metal phosphide poisoning in a disaster-stricken area. Can early hemodialysis improve outcomes? Malnutrition elevates delirium and ICU stay among critically ill older adult COVID-19 patients Malnutrition elevates delirium and ICU stay among critically ill older adult COVID-19 patients The Role of Neutrophil-to-Lymphocyte Ratio (NLR) in Urosepsis-Associated Delirium Nursing Intervention to Prevent and Manage Delirium in Critically Ill Patients: A Scoping Review A proof of concept for microcirculation monitoring using machine learning based hyperspectral imaging in critically ill patients: a monocentric observational study Frailty, Outcomes, Recovery and Care Steps of Critically Ill Patients (FORECAST): a prospective, multi-centre, cohort study Corticosteroids in critically ill patients: A narrative review Alpha2 Agonist Use in Critically Ill Adults: A Focus on Sedation and Withdrawal Prevention Menopause depression: Under recognised and poorly treated Cross-sectional analysis of the association between household food insecurity and mental health conditions in children aged 5-11 years in Canada Braden score can independently predict 90-day mortality in critically ill patients with dementia Efficacy of melatonin in decreasing the incidence of delirium in critically ill adults: a randomized controlled trial Efficacy of melatonin in decreasing the incidence of delirium in critically ill adults: a randomized controlled trial Perceived injustice and pain-related outcomes in children with pain conditions: A systematic review Implications of opioid-sparing medications in critically ill patients: A scoping review Effectiveness of decision aids on critically ill patients' outcomes and family members' knowledge, anxiety, depression and decisional conflict: A systematic review and meta-analysis Impact of Adverse Childhood Experiences and Mental Health on School Success in Autistic Children: Findings from the 2016-2021 National Survey of Children's Health Mental health conditions and COVID-19 vaccine outcomes: A scoping review Emergency department pediatric mental and behavioral health patients transported by EMS and police: Trends and interventions Tocilizumab is associated with reduced delirium and coma in critically ill patients with COVID-19 Severe Maternal Morbidity and Mental Health Hospitalizations or Emergency Department Visits Coding of Childhood Psychiatric and Neurodevelopmental Disorders in Electronic Health Records of a Large Integrated Health Care System: Validation Study Severe Maternal Morbidity and Mental Health Hospitalizations or Emergency Department Visits Discovery of Delirium Biomarkers through Minimally Invasive Serum Molecular Fingerprinting The occurrence of and factors associated with mental ill-health amongst humanitarian aid workers: A systematic review and meta-analysis Building up bit by bit, parent's experiences of equine-assisted intervention among children and adolescents with mental illness: a grounded theory study Vulnerable conditions syndemic, depression, and suicidal ideation among school children in China: cross-sectional census findings Monitoring Persons' Rights to Equal Care: Registered nurses' Experiences of Caring for People with Mental Ill-Health and Somatic Comorbidity in Psychiatric Outpatient Care Coding of Childhood Psychiatric and Neurodevelopmental Disorders in Electronic Health Records of a Large Integrated Health Care System: Validation Study Interfaces of 'being healthy and being Ill': how is health being perceived by individuals with non-communicable chronic conditions? The Role of Artificial Intelligence in Identifying Depression and Anxiety: A Comprehensive Literature Review Mental health sequelae in survivors of cardiogenic shock complicating myocardial infarction. A population-based cohort study Mental health sequelae in survivors of cardiogenic shock complicating myocardial infarction. A population-based cohort study Mental health clinical pathways for children and young people with long-term health conditions: A systematic review Long-term outcomes after treatment of delirium during critical illness with antipsychotics (MIND-USA): a randomised, placebo-controlled, phase 3 trial Liberal or Restrictive Transfusion Strategy in Patients with Traumatic Brain Injury Scope-of-Practice Expansions Associated with Reduced Racial Disparities in Pediatric Mental Health Care Inflammatory markers, somatic complaints, use of medication and health care in 11-year-old children at familial high risk of schizophrenia or bipolar disorder compared with population-based controls. The Danish High Risk and Resilience Study - via 11 Inflammatory markers, somatic complaints, use of medication and health care in 11-year-old children at familial high risk of schizophrenia or bipolar disorder compared with population-based controls. The Danish High Risk and Resilience Study - via 11 Barriers to Mental Health Care Transition for Youth and Young Adults with Intellectual and Developmental Disabilities and Co-occurring Mental Health Conditions: Stakeholders' Perspectives Development and application of a risk nomogram for the prediction of risk of carbapenem-resistant Acinetobacter baumannii infections in neuro-intensive care unit: a mixed method study Adverse Childhood Experiences and Health Outcomes Among Transition-Age Autistic Youth Institutional Experience with Investigation and Service for Acute and Post-Traumatic Stress in the Pediatric Intensive Care Unit Psychotropic Medication Prescription Patterns in Down Syndrome in a Large Pediatric Specialty Clinic An evaluation of psychosocial sleep interventions for children with chronic health conditions: A systematic review Impact of the COVID-19 Pandemic on the Diagnostic Frequency and Medical Therapies Applied to Subjects With Functional Seizures Disparities in Access to Mental Health Services Among Children Diagnosed with Anxiety and Depression in the United States Disparities in spatiotemporal clustering of maternal mental health conditions before and during the COVID-19 pandemic Dental treatment provided to special needs children under general anesthesia in a tertiary care hospital - A cross sectional retrospective study The association between schizophrenia and increased COVID-19 mortality in a cohort of over 2 million people in Brazil Chronic Health Conditions and Longitudinal Employment in Survivors of Childhood Cancer Long-term exposure to PM2.5 air pollution and mental health: a retrospective cohort study in Ireland The mental health and traumatic experiences of mothers of children with 22q11DS Positive parenting practices support children at neurological risk during COVID-19: a call for accessible parenting interventions Neighborhood context and children's health care utilization and health outcomes: a comprehensive descriptive analysis of national survey data Identifying Post-Acute Sequelae of SARS-CoV-2 Among Children in New York State Medicaid Managed Care
Evidence Blueprint
Outcomes of critically ill children with pre-existing mental health conditions
![](https://psychiatryai.com/wp-content/uploads/2023/04/psychiatryai_com.webp)
☊ AI-Driven Related Evidence Nodes
(recent articles with at least 5 words in title)
More Evidence
![](https://psychiatryai.com/wp-content/uploads/2023/04/psychiatryai_com.webp)
Outcomes of critically ill children with pre-existing mental health conditions
🌐 365 Days
AI Virtual Reality Related Evidence Matrix
Effects of gabapentin on slow-wave sleep period in critically ill adult patients: A randomized controlled trial Association of Delirium with Long-Term Mortality in Critically Ill Patients with COPD Who Survived to Discharge: A Retrospective Cohort Study Retrospective Analysis of Burn Injuries in Children with Autism Spectrum Disorder Clinical Reasoning: A 17-Year-Old Adolescent Boy With New Altered Mental Status in the Pediatric Intensive Care Unit Roles of physical functioning and comorbid mental illness of chronically ill parents and their spouses' health status in adolescent functioning Delirium Associated with COVID-19 in Critically ill Children: An Observational Cohort Study Usefulness of the 4A's test for detecting delirium in critically ill patients: a multicenter prospective observation study Clinical Significance of the Prognostic Nutritional Index in Predicting Delirium among Critically Ill Patients: A Retrospective Cohort Study Clinical Significance of the Prognostic Nutritional Index in Predicting Delirium among Critically Ill Patients: A Retrospective Cohort Study Appropriateness of behavioural scales in the monitoring of pain in the critically ill patient unable to self-report Metal phosphide poisoning in a disaster-stricken area. Can early hemodialysis improve outcomes? Children and Young Adults With Inflammatory Bowel Disease Have an Increased Incidence and Risk of Developing Mental Health Conditions: A UK Population-Based Cohort Study Malnutrition elevates delirium and ICU stay among critically ill older adult COVID-19 patients Malnutrition elevates delirium and ICU stay among critically ill older adult COVID-19 patients The Role of Neutrophil-to-Lymphocyte Ratio (NLR) in Urosepsis-Associated Delirium Effect of level of sedation on outcomes in critically ill adult patients: a systematic review of clinical trials with meta-analysis and trial sequential analysis Nursing Intervention to Prevent and Manage Delirium in Critically Ill Patients: A Scoping Review A proof of concept for microcirculation monitoring using machine learning based hyperspectral imaging in critically ill patients: a monocentric observational study Frailty, Outcomes, Recovery and Care Steps of Critically Ill Patients (FORECAST): a prospective, multi-centre, cohort study Corticosteroids in critically ill patients: A narrative review Therapeutic Use of Cannabinoids in Critically Ill Patients: A Survey of Intensive Care Physicians in Germany Alpha2 Agonist Use in Critically Ill Adults: A Focus on Sedation and Withdrawal Prevention Association of socioeconomic deprivation with outcomes in critically ill adult patients: an observational prospective multicenter cohort study Menopause depression: Under recognised and poorly treated Cross-sectional analysis of the association between household food insecurity and mental health conditions in children aged 5-11 years in Canada Children With Chronic Health Conditions and Social Needs: Investigating Outcomes to Drive Health System Improvements The impact of community engagement as a public health intervention to support the mental well-being of single mothers and children living under housing insecure conditions - a rapid literature review The Role of Pediatric Psychologists in Critical Care: Lessons Learned and Future Directions in Integrating Mental Health Care into Pediatric Intensive Care Units Braden score can independently predict 90-day mortality in critically ill patients with dementia Self-Care Mental Health App Intervention for Post-Intensive Care Syndrome-Family: A Randomized Pilot Study Efficiency of continuous positive airway pressure and high-flow nasal oxygen therapy in critically ill patients with COVID-19 Efficacy of melatonin in decreasing the incidence of delirium in critically ill adults: a randomized controlled trial Efficacy of melatonin in decreasing the incidence of delirium in critically ill adults: a randomized controlled trial Perceived injustice and pain-related outcomes in children with pain conditions: A systematic review Implications of opioid-sparing medications in critically ill patients: A scoping review Effectiveness of decision aids on critically ill patients' outcomes and family members' knowledge, anxiety, depression and decisional conflict: A systematic review and meta-analysis The effects of higher versus lower protein delivery in critically ill patients: an updated systematic review and meta-analysis of randomized controlled trials with trial sequential analysis Co-occurring conditions in Down syndrome: Findings from a clinical database Efficacy of haloperidol to decrease the burden of delirium in adult critically ill patients: the EuRIDICE randomized clinical trial Comparative study showed that children faced a 78% higher risk of new-onset conditions after they had COVID-19 Physicians' beliefs and perceived importance of traumatic brain injury-associated agitation in critically ill patients: a survey of Canadian intensivists Impact of Adverse Childhood Experiences and Mental Health on School Success in Autistic Children: Findings from the 2016-2021 National Survey of Children's Health Mental health conditions and COVID-19 vaccine outcomes: A scoping review Emergency department pediatric mental and behavioral health patients transported by EMS and police: Trends and interventions Mental Health Conditions Among Children and Adolescents With Congenital Heart Disease: A Danish Population-Based Cohort Study Outcomes and Resource Utilization in Liver Transplant Recipients Who Underwent Expedited Transplant Evaluation Parent-child Nativity, Race, Ethnicity, and Common Mental Health Conditions among U.S. Children and Adolescents Tocilizumab is associated with reduced delirium and coma in critically ill patients with COVID-19 Severe Maternal Morbidity and Mental Health Hospitalizations or Emergency Department Visits Coding of Childhood Psychiatric and Neurodevelopmental Disorders in Electronic Health Records of a Large Integrated Health Care System: Validation Study Severe Maternal Morbidity and Mental Health Hospitalizations or Emergency Department Visits Mental ill-health and substance use among sexuality diverse adolescents: The critical role of school climate and teacher self-efficacy Impact of mental health comorbidity in children and young adults with inflammatory bowel disease: a UK population-based cohort study Discovery of Delirium Biomarkers through Minimally Invasive Serum Molecular Fingerprinting The occurrence of and factors associated with mental ill-health amongst humanitarian aid workers: A systematic review and meta-analysis Building up bit by bit, parent's experiences of equine-assisted intervention among children and adolescents with mental illness: a grounded theory study Perspectives of mental health clinicians on physical health of young people with early psychosis Mental Health Outcomes of Mothers of Children With Congenital Gastrointestinal Anomalies Are Similar to Control Mothers: A Longitudinal Retrospective Cohort Study Perinatal mental health and pregnancy-associated mortality: opportunities for change Vulnerable conditions syndemic, depression, and suicidal ideation among school children in China: cross-sectional census findings The predictive value of confusion assessment method-intensive care unit and intensive care delirium screening checklist for delirium in critically ill patients in the intensive care unit: A systematic review and meta-analysis Monitoring Persons' Rights to Equal Care: Registered nurses' Experiences of Caring for People with Mental Ill-Health and Somatic Comorbidity in Psychiatric Outpatient Care A scoping review of cardiovascular risk factor screening rates in general or family practice attendees living with severe mental ill-health Surf therapy for improving child and adolescent mental health: A pilot randomised control trial