Evidence
Med Klin Intensivmed Notfmed. 2024 Apr 29. doi: 10.1007/s00063-024-01142-y. Online ahead of print.
ABSTRACT
Acute kidney injury (AKI) is a common problem in critically ill patients and is associated with increased morbidity and mortality. Since 2012, AKI has been defined according to the KDIGO (Kidney Disease Improving Global Outcome) guidelines. As some biomarkers are now available that can provide useful clinical information, a new definition including a new stage 1S has been proposed by an expert group of the Acute Disease Quality Initiative (ADQI). At this stage, classic AKI criteria are not yet met, but biomarkers are already positive defining subclinical AKI. This stage 1S is associated with a worse patient outcome, regardless of the biomarker chosen. The PrevAKI and PrevAKI-Multicenter trial also showed that risk stratification with a biomarker and implementation of the KDIGO bundle (in the high-risk group) can reduce the rate of moderate and severe AKI. In the absence of a successful clinical trial, conservative management remains the primary focus of treatment. This mainly involves optimization of hemodynamics and an individualized (restrictive) fluid management. The STARRT-AKI trial has shown that there is no benefit from accelerated initiation of renal replacement therapy. However, delaying too long might be associated with potential harm, as shown in the AKIKI2 study. Prospective studies are needed to determine whether artificial intelligence will play a role in AKI in the future, helping to guide treatment decisions and improve outcomes.
PMID:38683229 | DOI:10.1007/s00063-024-01142-y
Estimated reading time: 5 minute(s)
Latest: Psychiatryai.com #RAISR4D Evidence
Cool Evidence: Engaging Young People and Students in Real-World Evidence
Real-Time Evidence Search [Psychiatry]
AI Research
Recent developments in acute kidney injury : Definition, biomarkers, subphenotypes, and management
🌐 90 Days
AI Virtual Reality Related Evidence Matrix
- APASL clinical practice guidelines on the management of acute kidney injury in acute-on-chronic liver failure
- Development and external validation of a machine learning model for the prediction of persistent acute kidney injury stage 3 in multi-centric, multi-national intensive care cohorts
- Controlled Mechanical Ventilation in Critically Ill Patients and the Potential Role of Venous Bagging in Acute Kidney Injury
- Interpretable machine learning model for predicting acute kidney injury in critically ill patients
- Interpretable machine learning-based individual analysis of acute kidney injury in immune checkpoint inhibitor therapy
- Forecasting acute kidney injury and resource utilization in ICU patients using longitudinal, multimodal models
- Clinical Presentation, Pathological Spectrum, and Outcomes of Alcoholic Cirrhosis-Related Immunoglobulin A Nephropathy
- Clinical Presentation, Pathological Spectrum, and Outcomes of Alcoholic Cirrhosis-Related Immunoglobulin A Nephropathy
- A case of suicide secondary to diethylene glycol intentional ingestion
- Effects of Cognitive Behavioural Therapy on Mental Health and Sleep in Acute Kidney Injury Patients with Ureteral Calculi in the Emergency Department: A Retrospective Study
- Effects of Cognitive Behavioural Therapy on Mental Health and Sleep in Acute Kidney Injury Patients with Ureteral Calculi in the Emergency Department: A Retrospective Study
- Metformin Use in Type 2 Diabetics and Delirium After Noncardiac Surgery: A Retrospective Cohort Analysis
- Nephrological Detrimental Impacts Resulting From Novel Immunotherapy Drugs Used in the Treatment of Cancer: A Systematic Review
- Alcoholism and Immobility Induced Rhabdomyolysis Culminating in Hemodialysis
- Deep-learning model for evaluating histopathology of acute renal tubular injury
- Pediatric early-phase anorexia nervosa without hypokalemia exhibiting acute tubular injury: a case report
- Predictors of Adverse Drug Reaction-Related Hospitalisations Among People with Dementia: A Retrospective Case-Control Study
- Capacity for the management of kidney failure in the International Society of Nephrology Western Europe region: report from the 2023 ISN Global Kidney Health Atlas (ISN-GKHA)
- Effect of Telemedicine Support for Intraoperative Anaesthesia Care on Postoperative Outcomes: The TECTONICS Randomised Clinical Trial
- Targeting metabolic-associated fatty liver disease in diabetic kidney disease: A call to action
- Association of nirmatrelvir-ritonavir with post-acute sequelae and mortality in patients admitted to hospital with COVID-19: a retrospective cohort study
- Association of nirmatrelvir-ritonavir with post-acute sequelae and mortality in patients admitted to hospital with COVID-19: a retrospective cohort study
- A Case of Rhabdomyolysis Induced by Antipsychotic Medication With Creatine Kinase (CK) Levels Elevated to 420,000 U/L, Resulting in Acute Kidney Injury (AKI) and Necessitating Hemodialysis
- Evaluation of management of CT scan proved solid organ injury in blunt injury abdomen-a prospective study
- Chronic immunosuppression across 12 months and high ability of acute and subacute CNS-injury biomarker concentrations to identify individuals with complicated mTBI on acute CT and MRI
- Chronic immunosuppression across 12 months and high ability of acute and subacute CNS-injury biomarker concentrations to identify individuals with complicated mTBI on acute CT and MRI
- Towards cascading genetic risk in Alzheimer's disease
- Determinants of serious health outcome-free status in middle-aged and older people with dysglycaemia: Exploratory analysis of the ORIGIN trial
- Oculomics: A Crusade Against the Four Horsemen of Chronic Disease
- Therapeutic potential of Lactobacillus casei and Chlorella vulgaris in high-fat diet-induced non-alcoholic fatty liver disease (NAFLD)-associated kidney damages: a stereological study
- A new era in the science and care of kidney diseases
- Exploratory factor analysis yields grouping of brain injury biomarkers significantly associated with outcomes in neonatal and pediatric ECMO
- Putative Risk Biomarkers of Bipolar Disorder in At-risk Youth
- Putative Risk Biomarkers of Bipolar Disorder in At-risk Youth
- Frailty and In-Hospital Outcomes for Management of Cardiogenic Shock without Acute Myocardial Infarction
- A state-of-the-art overview of candidate diagnostic biomarkers for attention-Deficit/Hyperactivity disorder (ADHD)
- Non-invasive Scores and Serum Biomarkers for Fatty Liver in the Era of Metabolic Dysfunction-associated Steatotic Liver Disease (MASLD): A Comprehensive Review From NAFLD to MAFLD and MASLD
- Non-invasive Scores and Serum Biomarkers for Fatty Liver in the Era of Metabolic Dysfunction-associated Steatotic Liver Disease (MASLD): A Comprehensive Review From NAFLD to MAFLD and MASLD
- Inflammation and Adverse Outcomes in Patients With Acute Ischemic Stroke With and Without Chronic Kidney Disease
- A cross-sectional study of α-synuclein seed amplification assay in Alzheimer's disease neuroimaging initiative: Prevalence and associations with Alzheimer's disease biomarkers and cognitive function
- Endothelial receptor proteins in acute venous thrombosis and delayed thrombus resolution in cerebral sinus vein thrombosis
- Artificial intelligence in kidney transplant pathology
- Pros and cons of live kidney donation in prediabetics: A critical review and way forward
- Plasma biomarkers increase diagnostic confidence in patients with Alzheimer's disease or frontotemporal lobar degeneration
- Smell the smoke before one sees the fire-The oligosymptomatic prodromal phase of neurodegenerative diseases
- Intraperitoneal versus intranasal administration of lipopolysaccharide in causing sepsis severity in a murine model: a preliminary comparison
- Patterns of Statin Therapy Use and Associated Outcomes in Older Veterans Across Kidney Function
- The role of biomarkers in the early detection of pancreatic cancer
- Blood biomarkers open a window to brain pathophysiology in Alzheimer's disease
- Alzheimer blood biomarkers: practical guidelines for study design, sample collection, processing, biobanking, measurement and result reporting
- Differentiating Prodromal Dementia with Lewy Bodies from Prodromal Alzheimer's Disease: A Pragmatic Review for Clinicians
- Associations of tau, Aβ, and brain volume of the Papez circuit with cognition in Alzheimer's disease
- MAFLD as part of systemic metabolic dysregulation
- MAFLD as part of systemic metabolic dysregulation
- Biomarkers of Bipolar Disorder in Late Life: An Evidence-Based Systematic Review
- Blood Pressure Variability and Plasma Biomarkers of Neuronal Injury and Alzheimer's Disease: A Clinic-Based Study of Patients with Diseases Along the Heart-Brain Axis
- Our experience with blast and gunshot induced traumatic vascular injuries at Somalia's major vascular referral center
- Our experience with blast and gunshot induced traumatic vascular injuries at Somalia's major vascular referral center
- Time trends in preemptive kidney transplantation in Europe: an era registry study
- Echocardiographic measures of the left heart and cerebrospinal fluid biomarkers of Alzheimer's disease pathology in cognitively intact adults: The CABLE study
- Mental health and professional outcomes in parents of children with chronic kidney disease
- Associations among plasma, MRI, and amyloid PET biomarkers of Alzheimer's disease and related dementias and the impact of health-related comorbidities in a community-dwelling cohort
- Long-Term Clinical Outcomes of Acute Kidney Disease in Patients Receiving Extracorporeal Membrane Oxygenation
- Outcomes of Combined Liver-Kidney Transplantation - Single Center Experience
Evidence Blueprint
Recent developments in acute kidney injury : Definition, biomarkers, subphenotypes, and management
☊ AI-Driven Related Evidence Nodes
(recent articles with at least 5 words in title)
More Evidence
Recent developments in acute kidney injury : Definition, biomarkers, subphenotypes, and management
🌐 365 Days
AI Virtual Reality Related Evidence Matrix
- APASL clinical practice guidelines on the management of acute kidney injury in acute-on-chronic liver failure
- Development and external validation of a machine learning model for the prediction of persistent acute kidney injury stage 3 in multi-centric, multi-national intensive care cohorts
- Controlled Mechanical Ventilation in Critically Ill Patients and the Potential Role of Venous Bagging in Acute Kidney Injury
- Interpretable machine learning model for predicting acute kidney injury in critically ill patients
- Community-acquired acute kidney injury in India: data from ISN-acute kidney injury registry
- Dexmedetomidine Alleviates Ischemia/Reperfusion-Associated Acute Kidney Injury by Enhancing Autophagic Activity via the α2-AR/AMPK/mTOR Pathway
- Intraoperative hemodynamics and risk of cardiac surgery-associated acute kidney injury: An observation study and a feasibility clinical trial
- Interpretable machine learning-based individual analysis of acute kidney injury in immune checkpoint inhibitor therapy
- Forecasting acute kidney injury and resource utilization in ICU patients using longitudinal, multimodal models
- The progression of hepatorenal syndrome-acute kidney injury in acute alcohol-associated hepatitis: renal outcomes after liver transplant
- The effects of higher versus lower protein delivery in critically ill patients: an updated systematic review and meta-analysis of randomized controlled trials with trial sequential analysis
- Clinical Presentation, Pathological Spectrum, and Outcomes of Alcoholic Cirrhosis-Related Immunoglobulin A Nephropathy
- Clinical Presentation, Pathological Spectrum, and Outcomes of Alcoholic Cirrhosis-Related Immunoglobulin A Nephropathy
- A case of suicide secondary to diethylene glycol intentional ingestion
- Effects of Cognitive Behavioural Therapy on Mental Health and Sleep in Acute Kidney Injury Patients with Ureteral Calculi in the Emergency Department: A Retrospective Study
- Effects of Cognitive Behavioural Therapy on Mental Health and Sleep in Acute Kidney Injury Patients with Ureteral Calculi in the Emergency Department: A Retrospective Study
- Clinical characteristics and prognosis of hospitalized patients with moderate alcohol-associated hepatitis
- Metformin Use in Type 2 Diabetics and Delirium After Noncardiac Surgery: A Retrospective Cohort Analysis
- Absolute and Relative Risks of Kidney Outcomes Associated With Lithium vs Valproate Use in Sweden
- Nephrological Detrimental Impacts Resulting From Novel Immunotherapy Drugs Used in the Treatment of Cancer: A Systematic Review
- Alcoholism and Immobility Induced Rhabdomyolysis Culminating in Hemodialysis
- Prognostic and diagnostic scoring models in acute alcohol-associated hepatitis: A review comparing the performance of different scoring systems
- Kidney transplantation for end-stage renal disease after third allogeneic hematopoietic stem cell transplantation for Philadelphia chromosome-positive acute lymphoblastic leukemia
- Impact of Aspirin Use on Outcomes in Patients With Hepatocellular Cancer: A Nationwide Analysis
- Comments on: Nonalcoholic Fatty Liver Disease Predicts Acute Kidney Injury Readmission in Heart Failure Hospitalizations: A Nationwide Analysis
- Deep-learning model for evaluating histopathology of acute renal tubular injury
- Pediatric early-phase anorexia nervosa without hypokalemia exhibiting acute tubular injury: a case report
- Predictors of Adverse Drug Reaction-Related Hospitalisations Among People with Dementia: A Retrospective Case-Control Study
- Capacity for the management of kidney failure in the International Society of Nephrology Western Europe region: report from the 2023 ISN Global Kidney Health Atlas (ISN-GKHA)
- Chronic kidney disease incidences in Thai outpatients diagnosed with psychiatric illnesses receiving lithium maintenance therapy: a university hospital-based study
- Remission in Type 2 Inflammatory Diseases: Current Evidence, Unmet Needs, and Suggestions for Defining Remission in Chronic Rhinosinusitis with Nasal Polyps
- Multi-Omic Blood Biomarkers as Dynamic Risk Predictors in Late-Onset Alzheimer's Disease
- Effect of Telemedicine Support for Intraoperative Anaesthesia Care on Postoperative Outcomes: The TECTONICS Randomised Clinical Trial
- Proteomic analysis investigating kidney transplantation outcomes- a scoping review
- Targeting metabolic-associated fatty liver disease in diabetic kidney disease: A call to action
- Association of nirmatrelvir-ritonavir with post-acute sequelae and mortality in patients admitted to hospital with COVID-19: a retrospective cohort study
- Association of nirmatrelvir-ritonavir with post-acute sequelae and mortality in patients admitted to hospital with COVID-19: a retrospective cohort study
- A Case of Rhabdomyolysis Induced by Antipsychotic Medication With Creatine Kinase (CK) Levels Elevated to 420,000 U/L, Resulting in Acute Kidney Injury (AKI) and Necessitating Hemodialysis
- Evaluation of management of CT scan proved solid organ injury in blunt injury abdomen-a prospective study
- Chronic immunosuppression across 12 months and high ability of acute and subacute CNS-injury biomarker concentrations to identify individuals with complicated mTBI on acute CT and MRI
- Chronic immunosuppression across 12 months and high ability of acute and subacute CNS-injury biomarker concentrations to identify individuals with complicated mTBI on acute CT and MRI
- Towards cascading genetic risk in Alzheimer's disease
- Determinants of serious health outcome-free status in middle-aged and older people with dysglycaemia: Exploratory analysis of the ORIGIN trial
- Neglected Trivial Trauma - A Cause for Pseudo-acute Kidney Injury
- Study design for development of novel safety biomarkers of drug-induced liver injury by the translational safety biomarker pipeline (TransBioLine) consortium: a study protocol for a nested case-control study
- Oculomics: A Crusade Against the Four Horsemen of Chronic Disease
- Therapeutic potential of Lactobacillus casei and Chlorella vulgaris in high-fat diet-induced non-alcoholic fatty liver disease (NAFLD)-associated kidney damages: a stereological study
- Quality of Life and Health-related Quality of Life in Patients with End-stage Kidney Disease Undergoing Hemodialysis: A Literature Review
- A new era in the science and care of kidney diseases
- Exploratory factor analysis yields grouping of brain injury biomarkers significantly associated with outcomes in neonatal and pediatric ECMO
- Diagnostic performance of circulating biomarkers for non-alcoholic steatohepatitis
- Putative Risk Biomarkers of Bipolar Disorder in At-risk Youth
- Putative Risk Biomarkers of Bipolar Disorder in At-risk Youth
- Frailty and In-Hospital Outcomes for Management of Cardiogenic Shock without Acute Myocardial Infarction
- A state-of-the-art overview of candidate diagnostic biomarkers for attention-Deficit/Hyperactivity disorder (ADHD)
- Non-invasive Scores and Serum Biomarkers for Fatty Liver in the Era of Metabolic Dysfunction-associated Steatotic Liver Disease (MASLD): A Comprehensive Review From NAFLD to MAFLD and MASLD
- Non-invasive Scores and Serum Biomarkers for Fatty Liver in the Era of Metabolic Dysfunction-associated Steatotic Liver Disease (MASLD): A Comprehensive Review From NAFLD to MAFLD and MASLD
- Inflammation and Adverse Outcomes in Patients With Acute Ischemic Stroke With and Without Chronic Kidney Disease
- A cross-sectional study of α-synuclein seed amplification assay in Alzheimer's disease neuroimaging initiative: Prevalence and associations with Alzheimer's disease biomarkers and cognitive function
- Regional versus general anesthesia in older patients for hip fracture surgery: a systematic review and meta-analysis of randomized controlled trials
- Cognitive impairment and the blood-brain barrier in chronic kidney disease: role of the uremic toxins
- Endothelial receptor proteins in acute venous thrombosis and delayed thrombus resolution in cerebral sinus vein thrombosis
- Artificial intelligence in kidney transplant pathology
- Pros and cons of live kidney donation in prediabetics: A critical review and way forward