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Autism Res. 2023 Nov 1. doi: 10.1002/aur.3043. Online ahead of print.
ABSTRACT
Sex differences in the age of autism diagnosis during childhood have been documented consistently but remain poorly understood. In this study, we used electronic health records data from a diverse, academic medical center to quantify differences in the age of autism diagnosis between boys and girls and identify associations between the age of diagnosis and co-occurring neurodevelopmental, psychiatric, and medical conditions. An established computable phenotype was used to identify all autism diagnoses within the Duke University Health System between 2014 and 2021. Co-occurring neurodevelopmental and psychiatric diagnoses as well as visits to specific medical and supportive services were identified in the 2 years prior to the autism diagnosis. Cox proportional hazards models were fitted to quantify associations between diagnosis age and sex with and without controlling for the presence of each co-occurring diagnosis and visit type. Records from 1438 individuals (1142 boys and 296 girls) were included. Girls were more likely to be diagnosed either before age 3 (
PMID:37909391 | DOI:10.1002/aur.3043
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Sex differences in the age of childhood autism diagnosis and the impact of co-occurring conditions
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Sex differences in the age of childhood autism diagnosis and the impact of co-occurring conditions
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