Evidence
![](https://psychiatryai.com/wp-content/uploads/2023/04/psychiatryai_com.webp)
Rev Med Chil. 2022 Nov;150(11):1540-1544. doi: 10.4067/S0034-98872022001101540.
ABSTRACT
Liver transplantation is the only effective therapy to reduce the high mortality associated with acute liver failure and acute on chronic liver failure (ACLF). Single-pass albumin dialysis (SPAD) is an extracorporeal supportive therapy used as a bridge to liver transplantation or regeneration. We report a 44-year-old man with alcoholic cirrhosis admitted for critical COVID-19 pneumonia that evolves with ACLF. SPAD technique was performed completing six sessions, with a reduction of bilirubin and ammonia levels. He evolved with severe respiratory failure and refractory septic shock, dying. SPAD is a safe and efficient technique aimed to eliminate liver toxins, preventing multiorgan damage interrupting the process known as the “autointoxication hypothesis”. It is easy to implement in any critical patient unit and has lower costs than other extracorporeal liver support therapies.
PMID:37358181 | DOI:10.4067/S0034-98872022001101540
![Google](https://www.google.com/images/branding/googlelogo/2x/googlelogo_light_color_92x30dp.png)
![Google Keep](https://www.gstatic.com/images/branding/product/1x/keep_48dp.png)
![Share on Linkedin](https://psychiatryai.com/wp-content/uploads/2023/10/linkedin-logo-png-2048-1.png)
Estimated reading time: 3 minute(s)
Latest: Psychiatryai.com #RAISR4D Evidence
![](/wp-content/uploads/2024/04/bd462cc11bcf0bd0d0d6f1d0f8b7cd04-modified-1.png)
Cool Evidence: Engaging Young People and Students in Real-World Evidence
![](/wp-content/uploads/2024/04/bd462cc11bcf0bd0d0d6f1d0f8b7cd04-modified-1.png)
Real-Time Evidence Search [Psychiatry]
![](/wp-content/uploads/2024/04/pubmed.png)
AI Research
![](/wp-content/uploads/2024/05/Il5nR_nf_400x400-modified-1.png)
Single-pass albumin dialysis as treatment of acute on chronic liver failure during COVID-19 pneumonia. report of one case
![](https://psychiatryai.com/wp-content/uploads/2023/04/psychiatryai_com.webp)
🌐 90 Days
AI Virtual Reality Related Evidence Matrix
APASL clinical practice guidelines on the management of acute kidney injury in acute-on-chronic liver failure Outcome of individuals with alcoholic cirrhosis hospitalized with first decompensation and their predictors Comparison of a Novel Score "NOD-ACLF" to Other Established Prognostic Scores for Prediction of Mortality in APASL-ACLF Patients: A Cohort Study from a Tertiary Care Center of North India Transfusion-associated acute lung injury following albumin treatment in liver disease Transfusion-associated acute lung injury following albumin treatment in liver disease Critical care management of acute liver failure Hepatic compartment syndrome, a rare complication after any liver insult or liver transplantation: Three case reports and literature review Outcomes and risk factors for mortality in clostridioides difficile infection in patients with NAFLD and NASH Outcomes of Combined Liver-Kidney Transplantation - Single Center Experience Successful Recovery of a Catatonic Patient with Severe Pneumonia and Respiratory Failure: Modified Electroconvulsive Therapy Following Tracheotomy The Role of Cytokines in the Pathogenesis and Treatment of Alcoholic Liver Disease Case report: Rapid development of acute symptomatic portal vein system thrombosis after endoscopic variceal therapy in a patient with liver cirrhosis H2FPEF Scores Are Increased in Patients with NASH Cirrhosis and Are Associated with Post-liver Transplant Heart Failure COVID-19 in Individuals with Chronic Liver Diseases Inflammatory liver diseases and susceptibility to sepsis Role of albumin infusion in cirrhosis-associated complications Intrapulmonary Shunting and Paradoxical Air Embolism in Liver Transplantation: A Case Report Liver cirrhosis in a patient with alcohol dependence and autoimmune hepatitis Decellularized Descemet Membrane Anterior Keratoplasty With Allogeneic Simple Limbal Epithelial Transplantation for Partial Limbal Stem Cell Deficiency Following Partial Keratolimbal Allograft Failure An Insight Into Various Manifestations of Leptospirosis: A Unique Case Series From a State in Eastern India High-flow nasal oxygen in infants and children for early respiratory management of pneumonia-induced acute hypoxemic respiratory failure: the CENTURI randomized clinical trial Clinical, experimental and pathophysiological effects of Yaq-001: a non-absorbab le, gut-restricted adsorbent in models and patients with cirrhosis The role of EEG and neuroimaging in the diagnosis of non-convulsive status epilepticus in Subacute Encephalopathy with Seizures in Alcoholics (SESA syndrome): a case report and overview of the literature The role of EEG and neuroimaging in the diagnosis of non-convulsive status epilepticus in Subacute Encephalopathy with Seizures in Alcoholics (SESA syndrome): a case report and overview of the literature Teduglutide-induced acute gastric mucosal necrosis in short bowel syndrome with hepatorenal failure: Case report Age and Sex in the Development of Hepatic Encephalopathy: Role of Alcohol Case of severe alcoholic hepatitis following acute pancreatitis Case of severe alcoholic hepatitis following acute pancreatitis Case of severe alcoholic hepatitis following acute pancreatitis Feasibility of multiorgan risk prediction with routinely collected diagnostics: a prospective cohort study in the UK Biobank Managing Superwarfarin Poisoning: A Challenging Case Integrated transcriptomics and histopathology approach identifies a subset of rejected donor livers with potential suitability for transplantation COVID-19-induced acute loss of consciousness in Marchiafava-Bignami disease: a case report Clinical presentation of severe COVID‑19 with heart failure: A single‑center retrospective study Apathetic Graves' disease with severe hepatic and renal dysfunction induced by COVID-19 infection: Case report and literature review Polysaccharides from Eucommia ulmoides Oliv. Leaves Alleviate Acute Alcoholic Liver Injury by Modulating the Microbiota-Gut-Liver Axis in Mice Role of lactate and lactate metabolism in liver diseases (Review) Spatial genomics: mapping human steatotic liver disease Inter-relationships of risk factors and pathways associated with all-cause mortality in patients with chronic schizophrenia Wilson Disease: Copper-Mediated Cuproptosis, Iron-Related Ferroptosis, and Clinical Highlights, with Comprehensive and Critical Analysis Update Wilson Disease: Copper-Mediated Cuproptosis, Iron-Related Ferroptosis, and Clinical Highlights, with Comprehensive and Critical Analysis Update Capacity for the management of kidney failure in the International Society of Nephrology Western Europe region: report from the 2023 ISN Global Kidney Health Atlas (ISN-GKHA) Hypertensive emergency due to a delayed dialysis modality transition in a patient with familial hypomagnesemia with hypercalciuria and nephrocalcinosis: a case report Hypertensive emergency due to a delayed dialysis modality transition in a patient with familial hypomagnesemia with hypercalciuria and nephrocalcinosis: a case report Hypertensive emergency due to a delayed dialysis modality transition in a patient with familial hypomagnesemia with hypercalciuria and nephrocalcinosis: a case report Review article: Hepatic steatosis and its associations with acute and chronic liver diseases Incretin-based investigational therapies for the treatment of MASLD/MASH 2022: Perioperative and critical care year in review for the cardiothoracic surgery team Choosing Appropriate Nutritional Therapy for Patients With Anorexia Nervosa Exhibiting Liver Dysfunction: A Case Report Association of nirmatrelvir-ritonavir with post-acute sequelae and mortality in patients admitted to hospital with COVID-19: a retrospective cohort study Association of nirmatrelvir-ritonavir with post-acute sequelae and mortality in patients admitted to hospital with COVID-19: a retrospective cohort study FGL1 and FGL2: emerging regulators of liver health and disease Kupffer cell diversity maintains liver function in alcohol-associated liver disease Role of prostaglandin E2 and its receptors in chronic liver disease A Rare Cause of Empyema and Bacteremia Due to Shewanella Species in Alcoholic Cirrhosis Patients: A Case Report and Comprehensive Review of Literature Biallelic variants in LARS1 induce steatosis in developing zebrafish liver via enhanced autophagy Biallelic variants in LARS1 induce steatosis in developing zebrafish liver via enhanced autophagy Inflammation in alcohol-associated hepatitis: pathogenesis and therapeutic targets Metallofullerenol alleviates alcoholic liver damage via ROS clearance under static magnetic and electric fields Prolonged exposure to lung-derived cytokines is associated with activation of microglia in patients with COVID-19 Hepatocellular Carcinoma: Prevention, Diagnosis, and Treatment Deficiency of leucine-rich repeat kinase 2 aggravates thioacetamide-induced acute liver failure and hepatic encephalopathy in mice Re-evaluation of the prospective risk analysis for artificial-intelligence driven cone beam computed tomography-based online adaptive radiotherapy after one year of clinical experience Re-evaluation of the prospective risk analysis for artificial-intelligence driven cone beam computed tomography-based online adaptive radiotherapy after one year of clinical experience
Evidence Blueprint
Single-pass albumin dialysis as treatment of acute on chronic liver failure during COVID-19 pneumonia. report of one case
![](https://psychiatryai.com/wp-content/uploads/2023/04/psychiatryai_com.webp)
☊ AI-Driven Related Evidence Nodes
(recent articles with at least 5 words in title)
More Evidence
![](https://psychiatryai.com/wp-content/uploads/2023/04/psychiatryai_com.webp)
Single-pass albumin dialysis as treatment of acute on chronic liver failure during COVID-19 pneumonia. report of one case
🌐 365 Days
AI Virtual Reality Related Evidence Matrix
The First Successful Living Donor Liver Transplantation for Acute-on-Chronic Liver Failure Caused by Severe Acute Necrotizing Pancreatitis: A Case Report Management of the acute on chronic liver failure in the intensive care unit Epidemiological characteristics of inpatients with liver failure at the Beijing You'an Hospital from 2012 to 2021 Liver Transplantation in Chronic Liver Disease and Acute on Chronic Liver Failure- Indication, Timing and Practices Liver Transplantation in Chronic Liver Disease and Acute on Chronic Liver Failure- Indication, Timing and Practices Mononuclear myeloid-derived suppressor cells expansion is associated with progression of liver failure in patients with acute decompensation of cirrhosis APASL clinical practice guidelines on the management of acute kidney injury in acute-on-chronic liver failure Granulocyte Colony Stimulating Factor in decompensated cirrhosis, acute alcoholic hepatitis, and acute-on-chronic liver failure: a comprehensive meta-analysis of randomized controlled trials Acute liver failure and aplastic crisis due to anorexia nervosa in an adolescent girl: a case report Outcome of individuals with alcoholic cirrhosis hospitalized with first decompensation and their predictors Comparison of a Novel Score "NOD-ACLF" to Other Established Prognostic Scores for Prediction of Mortality in APASL-ACLF Patients: A Cohort Study from a Tertiary Care Center of North India Non-alcoholic fatty liver disease and COVID-19: Pathologies that add their risks and effects Liver Transplantation for Acute Hepatic Failure Following Intentional Iron Overdose Histological characteristics in patients admitted to the hospital with alcoholic hepatitis complicated by acute-on-chronic liver failure Liver involvement in presence of heart disease and heart involvement in presence of liver disease: a conundrum Transfusion-associated acute lung injury following albumin treatment in liver disease Transfusion-associated acute lung injury following albumin treatment in liver disease Critical care management of acute liver failure Hepatic compartment syndrome, a rare complication after any liver insult or liver transplantation: Three case reports and literature review Hepatopulmonary Syndrome Diagnosis in the ICU: The Relevance of Bedside Contrast Saline Echocardiography Multiple Dimensions of using Mesenchymal Stem Cells for Treating Liver Diseases: From Bench to Beside Metabolic Disorders in Liver Transplant Recipients: The State of the Art Successful Recovery from Severe Alcoholic Hepatitis (SAH) for Third Time Outcomes and risk factors for mortality in clostridioides difficile infection in patients with NAFLD and NASH Outcomes of Combined Liver-Kidney Transplantation - Single Center Experience Management of alcoholic hepatitis: A clinical perspective Severe Acute Liver Injury: First Manifestation of Systemic Lupus Erythematosus Influence of chronic liver diseases on the course and outcome of COVID-19 Embolization of spontaneous portosystemic shunts as treatment for refractory hepatic encephalopathy A case of late-onset organizing pneumonia following COVID-19 infection in a post-kidney transplant patient Successful Recovery of a Catatonic Patient with Severe Pneumonia and Respiratory Failure: Modified Electroconvulsive Therapy Following Tracheotomy The Role of Cytokines in the Pathogenesis and Treatment of Alcoholic Liver Disease Prognostic and diagnostic scoring models in acute alcohol-associated hepatitis: A review comparing the performance of different scoring systems Pulmonary Embolization After Gastric Varices Obliteration Case report: Rapid development of acute symptomatic portal vein system thrombosis after endoscopic variceal therapy in a patient with liver cirrhosis H2FPEF Scores Are Increased in Patients with NASH Cirrhosis and Are Associated with Post-liver Transplant Heart Failure COVID-19 in Individuals with Chronic Liver Diseases A comparison between patients with various etiologies of cirrhosis and examination of cardiac risk factors limiting survival to liver transplantation Inflammatory liver diseases and susceptibility to sepsis Role of albumin infusion in cirrhosis-associated complications Intrapulmonary Shunting and Paradoxical Air Embolism in Liver Transplantation: A Case Report A glimpse into multimodal neuromonitoring in acute liver failure: a case report Liver cirrhosis in a patient with alcohol dependence and autoimmune hepatitis Alcohol-related cancer morbidity and mortality are stratified using modified albumin platelet product High-Intensity Statin Therapy and Associated Rhabdomyolysis in Chronic Liver Disease: A Case Report and Review of Literature Coeliac axis thrombosis and acute hepatic failure in a patient with dilated cardiomyopathy Liver injury: the therapeutic dilemma of homeopathy - a case report from Bangladesh Decellularized Descemet Membrane Anterior Keratoplasty With Allogeneic Simple Limbal Epithelial Transplantation for Partial Limbal Stem Cell Deficiency Following Partial Keratolimbal Allograft Failure An Insight Into Various Manifestations of Leptospirosis: A Unique Case Series From a State in Eastern India High-flow nasal oxygen in infants and children for early respiratory management of pneumonia-induced acute hypoxemic respiratory failure: the CENTURI randomized clinical trial Clinical, experimental and pathophysiological effects of Yaq-001: a non-absorbab le, gut-restricted adsorbent in models and patients with cirrhosis Albumin, an interesting and functionally diverse protein, varies from 'native' to 'effective' (Review) Study of liver cirrhosis over twenty consecutive years in adults in Southern China A successful case of deceased-donor liver transplantation from a donor with Marfan syndrome: a case report Kidney transplantation for end-stage renal disease after third allogeneic hematopoietic stem cell transplantation for Philadelphia chromosome-positive acute lymphoblastic leukemia The role of EEG and neuroimaging in the diagnosis of non-convulsive status epilepticus in Subacute Encephalopathy with Seizures in Alcoholics (SESA syndrome): a case report and overview of the literature The role of EEG and neuroimaging in the diagnosis of non-convulsive status epilepticus in Subacute Encephalopathy with Seizures in Alcoholics (SESA syndrome): a case report and overview of the literature The mitochondrial biliverdin exporter ABCB10 in hepatocytes mitigates neutrophilic inflammation in alcoholic hepatitis Life-Threatening Electrical Storm Following Liver Transplantation: A Case Report COVID-19-induced liver injury in infants, children, and adolescents Teduglutide-induced acute gastric mucosal necrosis in short bowel syndrome with hepatorenal failure: Case report Alcoholic liver disease - 2023 Therapeutic potential of oleanolic acid in liver diseases Age and Sex in the Development of Hepatic Encephalopathy: Role of Alcohol