Evidence
![](https://psychiatryai.com/wp-content/uploads/2023/04/psychiatryai_com.webp)
Br J Psychol. 2024 Jan 12. doi: 10.1111/bjop.12693. Online ahead of print.
ABSTRACT
Uncertainty has been a central concept in psychological theories of anxiety. However, this concept has been plagued by divergent connotations and operationalizations. The lack of consensus hinders the current search for cognitive and biological mechanisms of anxiety, jeopardizes theory creation and comparison, and restrains translation of basic research into improved diagnoses and interventions. Drawing upon uncertainty decomposition in Bayesian Decision Theory, we propose a well-defined conceptual structure of uncertainty in cognitive and clinical sciences, with a focus on anxiety. We discuss how this conceptual structure provides clarity and can be naturally applied to existing frameworks of psychopathology research. Furthermore, it allows formal quantification of various types of uncertainty that can benefit both research and clinical practice in the era of computational psychiatry.
PMID:38217080 | DOI:10.1111/bjop.12693
![Google](https://www.google.com/images/branding/googlelogo/2x/googlelogo_light_color_92x30dp.png)
![Google Keep](https://www.gstatic.com/images/branding/product/1x/keep_48dp.png)
![Share on Linkedin](https://psychiatryai.com/wp-content/uploads/2023/10/linkedin-logo-png-2048-1.png)
Estimated reading time: 3 minute(s)
Latest: Psychiatryai.com #RAISR4D Evidence
![](/wp-content/uploads/2024/04/bd462cc11bcf0bd0d0d6f1d0f8b7cd04-modified-1.png)
Cool Evidence: Engaging Young People and Students in Real-World Evidence
![](/wp-content/uploads/2024/04/bd462cc11bcf0bd0d0d6f1d0f8b7cd04-modified-1.png)
Real-Time Evidence Search [Psychiatry]
![](/wp-content/uploads/2024/04/pubmed.png)
AI Research
![](/wp-content/uploads/2024/05/Il5nR_nf_400x400-modified-1.png)
Understanding anxiety through uncertainty quantification
![](https://psychiatryai.com/wp-content/uploads/2023/04/psychiatryai_com.webp)
🌐 90 Days
AI Virtual Reality Related Evidence Matrix
A moderated chain mediation model examining the relation between smartphone addiction and intolerance of uncertainty among master's and PhD students EXPRESS: Uncertain World: How Children's Curiosity and Intolerance of Uncertainty Relate to their Behaviour and Emotion under Uncertainty Validation of the Approach-Avoidance Temperament Questionnaire in Individuals with Anxiety and Depression Evolutionary Strategies Enable Systematic and Reliable Uncertainty Quantification: A Proof-of-Concept Pilot Study on Resting-State Functional MRI Language Lateralization Evolutionary Strategies Enable Systematic and Reliable Uncertainty Quantification: A Proof-of-Concept Pilot Study on Resting-State Functional MRI Language Lateralization Intolerance of uncertainty and negative emotions among high school art students during COVID-19 pandemic: a moderated mediation analysis Psychopathy measurement practices moderate psychopathy's association with anxiety and depression: A comprehensive meta-analysis Exploring the conceptualisation, measurement, clinical utility and treatment of formal thought disorder in psychosis: A Delphi study Economic uncertainty and mental health: Global evidence, 1991 to 2019 Perceptual error based on Bayesian cue combination drives implicit motor adaptation Spanish translation of the Expert Recommendations for Implementing Change (ERIC) compilation The Structure of Identity Dysfunction in Self-Report Measures The Role of Intolerance of Uncertainty and Religiousness in Schizotypal Personality and Life Satisfaction: A Cross-Sectional Study Dissecting Bayes: Using influence measures to test normative use of probability density information derived from a sample test State and trait predictors of cognitive responses to acute stress and uncertainty Connection of social anxiety to impaired pattern of cognitive control and underlying motivational deficiencies: Evidence from event-related potentials Effect of wildfire on the prevalence of opioid misuse through anxiety among young adults in the United States: a modeling study An Expanded Conceptual Framework for Understanding Irritability in Childhood: The Role of Cognitive Control Processes Alexithymia, intolerance to uncertainty and mental health difficulties in adolescents with Type 1 diabetes mellitus A Measurement Invariance Analysis of the Anxiety Scale for Autism-Adults in a Sample of Autistic and Non-Autistic Men and Women The relationship between competitive anxiety and athlete burnout in college athlete: the mediating roles of competence and autonomy : [Author] What influences antibiotic initiation? Developing a scale to measure nursing behaviour in residential aged-care facilities Allostatic interoceptive overload across psychiatric and neurological conditions Neural activity differentiates novel and learned event boundaries Signs of front-line healthcare professionals' information anxiety during the COVID-19 pandemic: Grounded theory study in a Wuhan hospital Is political anxiety different than general anxiety? Longitudinal Relationship Between Psychological Capital and Anxiety in College Students: The Mediating Effect of Emotion Reregulation Strategy and Moderating Effect of Parent-Child Relationship Your Need for Cognition, Cognitive Flexibility, and Cognitive Emotion Regulation Strategies Matter! The Path beyond a Satisfied Life Acquired Capability for Suicide: An Evolutionary Concept Analysis Higher order affordances Association between problematic social networking use and anxiety symptoms: a systematic review and meta-analysis The double empathy problem: A derivation chain analysis and cautionary note The double empathy problem: A derivation chain analysis and cautionary note IMPACT OF THE COVID-19 PANDEMIC ON ELECTIVE KNEE SURGERIES IN ATHLETES Intolerance of uncertainty does not significantly predict decisions about delayed, probabilistic rewards: A failure to replicate Luhmann, C. C., Ishida, K., & Hajcak, G. (2011) Prediction of caregiver psychological distress in amyotrophic lateral sclerosis: A cross-sectional study Prediction of caregiver psychological distress in amyotrophic lateral sclerosis: A cross-sectional study Social activities in multidomain dementia prevention interventions: insights from practice and a blueprint for the future Effects of Cognitive Behavioural Therapy on Mental Health and Sleep in Acute Kidney Injury Patients with Ureteral Calculi in the Emergency Department: A Retrospective Study Effects of Cognitive Behavioural Therapy on Mental Health and Sleep in Acute Kidney Injury Patients with Ureteral Calculi in the Emergency Department: A Retrospective Study Postoperative cognitive dysfunction: a concept analysis A concept analysis of psychological trauma in labour and delivery nurses Cancer and Fertility: Exploring Uncertainty Management Strategies of Young Adult Female Survivors Clinical utility of the at-risk for psychosis state beyond transition: A multidimensional network analysis Average treatment effects on binary outcomes with stochastic covariates Early provision of clinical information with an 'opt in' approach improves patient experience in tonsillectomy referrals Using non-pharmacological interventions to manage medical procedure-induced anxiety in children: a framework to guide best practice Central nervous system active medication use in Medicare enrollees receiving home health care: association with chronic pain and anxiety level Realist process evaluation of the knowledge translation programme of a patient-oriented research network Comparison of stress, anxiety and depression levels of health, education and security sector employees: The effect of psychological resilience Trust but Verify: Lessons Learned for the Application of AI to Case-Based Clinical Decision-Making From Postmarketing Drug Safety Assessment at the US Food and Drug Administration Medical Debt and the Mental Health Treatment Gap Among US Adults The Association between Problematic Instagram Use, Psychological Distress, and Well-Being: A Systematic Review and Meta-Analysis The Association between Problematic Instagram Use, Psychological Distress, and Well-Being: A Systematic Review and Meta-Analysis Overparenting and psychological wellbeing among Chinese adolescents: Findings based on latent growth modeling Under Pressure: Men's and Women's Sexual Performance Anxiety in the Sexual Interactions of Adult Couples Under Pressure: Men's and Women's Sexual Performance Anxiety in the Sexual Interactions of Adult Couples A Source Control Model for Treatment-Resistant Substance Use Disorder The association between economic uncertainty and suicide in Japan by age, sex, employment status, and population density: an observational study The association between economic uncertainty and suicide in Japan by age, sex, employment status, and population density: an observational study Trajectories of illness uncertainty among parents of children with atypical genital appearance due to differences of sex development Investigation of Appearance Anxiety Levels and Influencing Factors in Patients Undergoing Minimally Invasive Facial Cosmetic Procedures Depression and anxiety in multiple sclerosis. Review of a fatal combination Assessment of the Psychological Effects on Firefighters in the Aftermath of the Pazarcik and Elbistan Earthquakes in 2023
Evidence Blueprint
Understanding anxiety through uncertainty quantification
![](https://psychiatryai.com/wp-content/uploads/2023/04/psychiatryai_com.webp)
☊ AI-Driven Related Evidence Nodes
(recent articles with at least 5 words in title)
More Evidence
![](https://psychiatryai.com/wp-content/uploads/2023/04/psychiatryai_com.webp)
Understanding anxiety through uncertainty quantification
🌐 365 Days
AI Virtual Reality Related Evidence Matrix
Uncertainty in surrogate decision-making about end-of-life care for people with dementia: An integrative review Fear, Perceived Threat, and Anxiety During COVID-19 Pandemic: The Mediating Role of Cognitive Control/Flexibility and Intolerance of Uncertainty COVID-19 anxiety and its relation to anxiety-related disorder symptoms and mechanisms Uncertainty as a driver of the youth mental health crisis Concept analysis of uncertainty in people with mental disabilities A moderated chain mediation model examining the relation between smartphone addiction and intolerance of uncertainty among master's and PhD students EXPRESS: Uncertain World: How Children's Curiosity and Intolerance of Uncertainty Relate to their Behaviour and Emotion under Uncertainty Bayesian Decision-Making Under Uncertainty in Borderline Personality Disorder Relationship between Fear of COVID-19, Intolerance of Uncertainty, and Coping Strategies on University Students' Mental Health The relationship between COVID-19 stress and test anxiety in art students: the chain mediating roles of intolerance of uncertainty and sleep quality Validation of the Approach-Avoidance Temperament Questionnaire in Individuals with Anxiety and Depression Pandemic fatigue and depressive symptoms among college students in the COVID-19 context: indirect effects through sense of control and intolerance of uncertainty A pilot, single-arm feasibility study of an integrated cognitive-behavioral treatment for anxiety in young autistic children Evolutionary Strategies Enable Systematic and Reliable Uncertainty Quantification: A Proof-of-Concept Pilot Study on Resting-State Functional MRI Language Lateralization Evolutionary Strategies Enable Systematic and Reliable Uncertainty Quantification: A Proof-of-Concept Pilot Study on Resting-State Functional MRI Language Lateralization Larger comfortable interpersonal distances in adults exposed to child maltreatment: The role of depressive symptoms and social anxiety Urged to feel certain again: The role of emotion-related impulsivity on the relationships between intolerance of uncertainty and OCD symptom severity Adolescent mentalizing and childhood emotional abuse: implications for depression, anxiety, and borderline personality disorder features Fear of negative evaluation and intolerance of uncertainty: Assessing potential internalizing correlates of eating disorder-related clinical impairment and differences across diagnostic presentations Fear of negative evaluation and intolerance of uncertainty: Assessing potential internalizing correlates of eating disorder-related clinical impairment and differences across diagnostic presentations Sleep quality impacts the link between reactivity to uncertain threat and anxiety and alcohol use in youth Intolerance of uncertainty and negative emotions among high school art students during COVID-19 pandemic: a moderated mediation analysis Psychopathy measurement practices moderate psychopathy's association with anxiety and depression: A comprehensive meta-analysis Exploring the conceptualisation, measurement, clinical utility and treatment of formal thought disorder in psychosis: A Delphi study Economic uncertainty and mental health: Global evidence, 1991 to 2019 The cognitive reality monitoring network and theories of consciousness Perceptual error based on Bayesian cue combination drives implicit motor adaptation Why we should focus more attention on uncertainty distress and intolerance of uncertainty in adolescents and emerging adults A short version of the reflective functioning questionnaire: Validation in a greek sample Perceptual alterations in the relationship between sensory reactivity, intolerance of uncertainty, and anxiety in autistic children with and without ADHD Theory-Guided Care of Intimate Partner Violence Trauma Patients in the Acute Care Setting Using the Vulnerable Populations Conceptual Model Evolution, the Cognitive Sciences, and the Science of Victimization Psychometric properties of the Arabic version of the intolerance of uncertainty scale: a multinational study Spanish translation of the Expert Recommendations for Implementing Change (ERIC) compilation The Structure of Identity Dysfunction in Self-Report Measures Examining attentional control deficits in adolescents with test anxiety: An evidential synthesis using self-report, behavioral, and resting-state EEG measures Longitudinal relationship between harsh parenting and adolescent non-suicidal self-injury: The roles of basic psychological needs frustration and self-concept clarity Autistic traits associated with dichotomic thinking mediated by intolerance of uncertainty Intolerance of Uncertainty and Worry Prospectively Predict COVID-19 Anxiety and Distress: A 4-Year Longitudinal Study Intolerance of Uncertainty and Worry Prospectively Predict COVID-19 Anxiety and Distress: A 4-Year Longitudinal Study Uncertainty among patients with advanced-stage lung cancer Examining anxious temperament in anorexia nervosa: Behavioural inhibition and intolerance of uncertainty and their contribution to trait anxiety in adolescents with anorexia nervosa The Role of Intolerance of Uncertainty and Religiousness in Schizotypal Personality and Life Satisfaction: A Cross-Sectional Study State of the art in psychological therapies for psychosis: Family interventions for psychosis Dissecting Bayes: Using influence measures to test normative use of probability density information derived from a sample test Anxiety symptoms without depression are associated with cognitive control network (CNN) dysfunction: An fNIRS study State and trait predictors of cognitive responses to acute stress and uncertainty Connection of social anxiety to impaired pattern of cognitive control and underlying motivational deficiencies: Evidence from event-related potentials Effect of wildfire on the prevalence of opioid misuse through anxiety among young adults in the United States: a modeling study An Expanded Conceptual Framework for Understanding Irritability in Childhood: The Role of Cognitive Control Processes Japanese Society of Anxiety and Related Disorders/Japanese Society of Neuropsychopharmacology: Clinical practice guideline for social anxiety disorder (2021) Alexithymia, intolerance to uncertainty and mental health difficulties in adolescents with Type 1 diabetes mellitus A Measurement Invariance Analysis of the Anxiety Scale for Autism-Adults in a Sample of Autistic and Non-Autistic Men and Women A new network analysis model in anorexia nervosa patients based on self-reported eating disorder symptoms, psychological distress, and cognitive flexibility Novelty and uncertainty differentially drive exploration across development The relationship between competitive anxiety and athlete burnout in college athlete: the mediating roles of competence and autonomy : [Author] What influences antibiotic initiation? Developing a scale to measure nursing behaviour in residential aged-care facilities End-to-End Multi-task Learning Architecture for Brain Tumor Analysis with Uncertainty Estimation in MRI Images Collective memory: between individual systems of consciousness and social systems Profiles of intolerance of uncertainty, separation anxiety, and negative affectivity in emerging adulthood: A person-centered approach Justifying by degrees: A grounded theory of men's decision-making process in infidelity Allostatic interoceptive overload across psychiatric and neurological conditions Neural activity differentiates novel and learned event boundaries Network analysis of social anxiety and problematic mobile phone use in Chinese adolescents: A longitudinal study