Psychiatry AI RAISR 4D System Psychiatry + Mental Health

4 May 2024

cGAS/STING signaling pathway-mediated microglial activation in the PFC underlies chronic ethanol exposure-induced anxiety-like behaviors in mice

Int Immunopharmacol. 2024 May 2;134:112185. doi: 10.1016/j.intimp.2024.112185. Online ahead of print.ABSTRACTChronic ethanol consumption is a prevalent condition in contemporary society and exacerbates anxiety symptoms in...

Neuropathology

4 May 2024

Microscope-integrated optical coherence tomography for in vivo human brain tumor detection with artificial intelligence

J Neurosurg. 2024 May 3:1-9. doi: 10.3171/2024.1.JNS231511. Online ahead of print.ABSTRACTOBJECTIVE: It has been shown that optical coherence tomography (OCT) can identify brain tumor tissue...

Neuropathology

4 May 2024

Metabolic models predict fotemustine and the combination of eflornithine/rifamycin and adapalene/cannabidiol for the treatment of gliomas

Brief Bioinform. 2024 Mar 27;25(3):bbae199. doi: 10.1093/bib/bbae199.ABSTRACTGliomas are the most common type of malignant brain tumors, with glioblastoma multiforme (GBM) having a median survival of...

Neuropathology

4 May 2024

The immunoglobulin superfamily ligand B7H6 subjects T cell responses to NK cell surveillance

Sci Immunol. 2024 May 3;9(95):eadj7970. doi: 10.1126/sciimmunol.adj7970. Epub 2024 May 3.ABSTRACTUnderstanding the mechanisms that regulate T cell immunity is critical for the development of effective...

Neuropathology

4 May 2024

Metabolic and neurobehavioral disturbances induced by purine recycling deficiency in Drosophila

Elife. 2024 May 3;12:RP88510. doi: 10.7554/eLife.88510.ABSTRACTAdenine phosphoribosyltransferase (APRT) and hypoxanthine-guanine phosphoribosyltransferase (HGPRT) are two structurally related enzymes involved in purine recycling in humans. Inherited mutations...

Anxiety

4 May 2024

The impact of negative affects on the high prevalence of anxiety, depression and stress in healthcare professionals

Work. 2024 May 3. doi: 10.3233/WOR-230257. Online ahead of print.ABSTRACTBACKGROUND: Psychiatric disorders are the conditions that most contribute to incapacity worldwide. While many healthcare professionals...

Anxiety

4 May 2024

Oscillation-specific nodal differences in Parkinson’s disease patients with anxiety

J Parkinsons Dis. 2024 Apr 29. doi: 10.3233/JPD-240055. Online ahead of print.ABSTRACTBACKGROUND: Parkinson's disease (PD) is a common neurodegenerative disorder that is predominantly known for...

Alcoholism

4 May 2024

Prevalence and risk of nonalcoholic fatty liver disease among adult psoriatic patients: A systematic review, meta-analysis, and trial sequential analysis

Medicine (Baltimore). 2024 May 3;103(18):e38007. doi: 10.1097/MD.0000000000038007.ABSTRACTBACKGROUND: This systematic review and meta-analysis aimed to report the evaluation of the prevalence and risk of nonalcoholic fatty...

Alcoholism

4 May 2024

Semaglutide combined with empagliflozin vs. monotherapy for non-alcoholic fatty liver disease in type 2 diabetes: Study protocol for a randomized clinical trial

PLoS One. 2024 May 3;19(5):e0302155. doi: 10.1371/journal.pone.0302155. eCollection 2024.ABSTRACTBACKGROUND: Nonalcoholic fatty liver disease (NAFLD) is strongly associated with type 2 diabetes mellitus (T2DM). Lifestyle intervention...

Alcoholism

4 May 2024

Early feasibility study with an implantable near-infrared spectroscopy sensor for glucose, ketones, lactate and ethanol

PLoS One. 2024 May 3;19(5):e0301041. doi: 10.1371/journal.pone.0301041. eCollection 2024.ABSTRACTOBJECTIVE: To evaluate the safety and performance of an implantable near-infrared (NIR) spectroscopy sensor for multi-metabolite monitoring...

Delirium

4 May 2024

Impact of intraoperative dexmedetomidine on postoperative delirium and pro-inflammatory cytokine levels in elderly patients undergoing thoracolumbar compression fracture surgery: A prospective, randomized, placebo-controlled clinical trial

Medicine (Baltimore). 2024 May 3;103(18):e37931. doi: 10.1097/MD.0000000000037931.ABSTRACTBACKGROUND: This study evaluates the efficacy of dexmedetomidine (DEX) in reducing postoperative delirium (POD) and modulating pro-inflammatory cytokines in...

Psychology

4 May 2024

Assessing the Feasibility and Preliminary Effects of a Web-Based Self-Management Program for Chronic Noncancer Pain: Mixed Methods Study

JMIR Hum Factors. 2024 May 3;11:e50747. doi: 10.2196/50747.ABSTRACTBACKGROUND: In Canada, adults with chronic noncancer pain face a persistent insufficiency of publicly funded resources, with the...

Brain

4 May 2024

Pyruvate dehydrogenase-E1α deficiency presenting as generalized dystonia: A genetic diagnosis with important clinical implications

Clin Neurol Neurosurg. 2024 Apr 30;241:108307. doi: 10.1016/j.clineuro.2024.108307. Online ahead of print.ABSTRACTPyruvate dehydrogenase complex (PDC) deficiency is a genetic mitochondrial disease mostly associated with severe...

Brain

4 May 2024

Remote optogenetic control of the enteric nervous system and brain-gut axis in freely-behaving mice enabled by a wireless, battery-free optoelectronic device

Biosens Bioelectron. 2024 Apr 16;258:116298. doi: 10.1016/j.bios.2024.116298. Online ahead of print.ABSTRACTWireless activation of the enteric nervous system (ENS) in freely moving animals with implantable optogenetic...

Violence

4 May 2024

Discrimination and violence against women migrant workers in Thailand during the COVID-19 pandemic: A mixed-methods study

PLoS One. 2024 May 3;19(5):e0300388. doi: 10.1371/journal.pone.0300388. eCollection 2024.ABSTRACTBACKGROUND: Women migrant workers are vulnerable to discrimination and violence, which are significant public health problems. These...

Dementia

4 May 2024

Neuroinflammation in dementia: A meta-analysis of PET imaging studies

Medicine (Baltimore). 2024 May 3;103(18):e38086. doi: 10.1097/MD.0000000000038086.ABSTRACTBACKGROUND: Dementia is a major public health challenge for aging societies worldwide. Neuroinflammation is thought to be a key...

Dementia

4 May 2024

p37 regulates VCP/p97 shuttling and functions in the nucleus and cytosol

Sci Adv. 2024 May 3;10(18):eadl6082. doi: 10.1126/sciadv.adl6082. Epub 2024 May 3.ABSTRACTThe AAA+-ATPase valosin-containing protein (VCP; also called p97 or Cdc48), a major protein unfolding machinery...

Dementia

4 May 2024

Effects of Bright Light Therapy on Agitation Among Older Adults Living with Dementia in Macao: A Pilot Study

J Gerontol Soc Work. 2024 May 3:1-19. doi: 10.1080/01634372.2024.2349603. Online ahead of print.ABSTRACTA randomized controlled trial was conducted to examine the effects of bright light...

Dementia

4 May 2024

Erratum to: Short term economic evaluation of the digital platform “support, monitoring and reminder technology for mild dementia” (SMART4MD) for people with mild cognitive impairment and their informal caregivers

J Alzheimers Dis. 2024 May 3. doi: 10.3233/JAD-249009. Online ahead of print.NO ABSTRACTPMID:38701171 | DOI:10.3233/JAD-249009

Dementia

4 May 2024

Unveiling the Molecular Interactions Between Human Transferrin and Limonene: Natural Compounds in Alzheimer’s Disease Therapeutics

J Alzheimers Dis. 2024;99(1):333-343. doi: 10.3233/JAD-240072.ABSTRACTBACKGROUND: Neurodegeneration is a term describing an irreversible process of neuronal damage. In recent decades, research efforts have been directed...

Dementia

4 May 2024

Prevalence and Determinants of Diagnosed Dementia: A Registry Linkage Study Linking Diagnosis of Dementia in the Population-Based HUNT Study to Registry Diagnosis of Dementia in Primary Care and Hospitals in Norway

J Alzheimers Dis. 2024;99(1):363-375. doi: 10.3233/JAD-240037.ABSTRACTBACKGROUND: A timely diagnosis of dementia can be beneficial for providing good support, treatment, and care, but the diagnostic rate...

Dementia

4 May 2024

Bodily and Visual-Cognitive Navigation Aids to Enhance Spatial Recall in Mild Cognitive Impairment

J Alzheimers Dis. 2024 May 2. doi: 10.3233/JAD-240122. Online ahead of print.ABSTRACTBACKGROUND: Individuals with mild cognitive impairment (MCI) syndrome often report navigation difficulties, accompanied by...

Psychopathy

4 May 2024

Grandiose narcissism associates with higher cognitive performance under stress through more efficient attention distribution: An eye-tracking study

PLoS One. 2024 May 3;19(5):e0302644. doi: 10.1371/journal.pone.0302644. eCollection 2024.ABSTRACTNarcissism is a part of the Dark Triad that consists also of the traits of Machiavellianism and...

PTSD

4 May 2024

Reply to Zijlstra: Resilience and Stress Are Heterogenic Too, We Should Act Accordingly

Am J Respir Crit Care Med. 2024 May 3. doi: 10.1164/rccm.202404-0790LE. Online ahead of print.NO ABSTRACTPMID:38701491 | DOI:10.1164/rccm.202404-0790LE

Psychosis

4 May 2024

Group Cohesion and Necessary Adaptations in Online Hearing Voices Peer Support Groups: Qualitative Study With Group Facilitators

JMIR Form Res. 2024 May 3;8:e51694. doi: 10.2196/51694.ABSTRACTBACKGROUND: Face-to-face hearing voices peer support groups (HVGs), a survivor-led initiative that enables individuals who hear voices to...

OCD

4 May 2024

Duchenne Muscular Dystrophy-Associated Neurobehavioral Difficulties: Insights from Clinical Practice

J Neuromuscul Dis. 2024 Apr 29. doi: 10.3233/JND-230251. Online ahead of print.ABSTRACTBACKGROUND: Emerging evidence underscores the high prevalence of neurobehavioral difficulties like ADHD, ASD and...

Neuroscience

4 May 2024

Evaluation of the Glasgow Coma Scale-Pupils score for predicting inpatient mortality among patients with traumatic subdural hematoma at United States trauma centers

J Neurosurg. 2024 May 3:1-9. doi: 10.3171/2024.2.JNS232695. Online ahead of print.ABSTRACTOBJECTIVE: The Glasgow Coma Scale-Pupils (GCS-P) score has been suggested to better predict patient outcomes...

Neuroscience

4 May 2024

Association of preprocedural antiplatelet use with decreased thromboembolic complications for intracranial aneurysms undergoing intrasaccular flow disruption

J Neurosurg. 2024 May 3:1-8. doi: 10.3171/2024.2.JNS232918. Online ahead of print.ABSTRACTOBJECTIVE: This study was conducted to investigate the impact of antiplatelet administration in the periprocedural...

Artificial Intelligence

4 May 2024

Classifying Interstitial Lung Disease: Omics Are in the Air

Am J Respir Crit Care Med. 2024 May 3. doi: 10.1164/rccm.202404-0748LE. Online ahead of print.NO ABSTRACTPMID:38701488 | DOI:10.1164/rccm.202404-0748LE

Artificial Intelligence

4 May 2024

AI identifies potent inducers of breast cancer stem cell differentiation based on adversarial learning from gene expression data

Brief Bioinform. 2024 Mar 27;25(3):bbae207. doi: 10.1093/bib/bbae207.ABSTRACTCancer stem cells (CSCs) are a subpopulation of cancer cells within tumors that exhibit stem-like properties and represent a...

Learning Disabilities

4 May 2024

Effects of hours of sleep on ImPACT concussion testing: comparing baseline with postinjury scores

J Neurosurg Pediatr. 2024 May 3:1-8. doi: 10.3171/2024.2.PEDS23437. Online ahead of print.ABSTRACTOBJECTIVE: The influence of sleep on baseline and postconcussion neurocognitive performance prior to Immediate...

Artificial Intelligence

4 May 2024

Evaluating the Quality of Postpartum Hemorrhage Nursing Care Plans Generated by Artificial Intelligence Models

J Nurs Care Qual. 2024 Apr 3. doi: 10.1097/NCQ.0000000000000766. Online ahead of print.ABSTRACTBACKGROUND: With the rapidly advancing technological landscape of health care, evaluating the potential...

Learning Disabilities

4 May 2024

Maternal distress during the COVID-19 outbreak: A socio-ecological perspective

PLoS One. 2024 May 3;19(5):e0302266. doi: 10.1371/journal.pone.0302266. eCollection 2024.ABSTRACTINTRODUCTION: Mothers faced an increased risk of adverse mental health outcomes during the COVID-19 pandemic compared to...

Artificial Intelligence

4 May 2024

How artificial intelligence can provide information about subdural hematoma: Assessment of readability, reliability, and quality of ChatGPT, BARD, and perplexity responses

Medicine (Baltimore). 2024 May 3;103(18):e38009. doi: 10.1097/MD.0000000000038009.ABSTRACTSubdural hematoma is defined as blood collection in the subdural space between the dura mater and arachnoid. Subdural hematoma...

Artificial Intelligence

4 May 2024

Deep learning-based spinal canal segmentation of computed tomography image for disease diagnosis: A proposed system for spinal stenosis diagnosis

Medicine (Baltimore). 2024 May 3;103(18):e37943. doi: 10.1097/MD.0000000000037943.ABSTRACTBACKGROUND: Lumbar disc herniation was regarded as an age-related degenerative disease. Nevertheless, emerging reports highlight a discernible shift, illustrating...

Artificial Intelligence

4 May 2024

IMPatienT: An Integrated Web Application to Digitize, Process and Explore Multimodal PATIENt daTa

J Neuromuscul Dis. 2024 Apr 29. doi: 10.3233/JND-230085. Online ahead of print.ABSTRACTMedical acts, such as imaging, lead to the production of various medical text reports...

Artificial Intelligence

4 May 2024

Revolutionizing tumor detection and classification in multimodality imaging based on deep learning approaches: methods, applications and limitations

J Xray Sci Technol. 2024 Apr 28. doi: 10.3233/XST-230429. Online ahead of print.ABSTRACTBACKGROUND: The emergence of deep learning (DL) techniques has revolutionized tumor detection and...

Artificial Intelligence

4 May 2024

Initial evaluation of a technologyenabled change in delivery of the dementia service during COVID-19 in North Warwickshire

Br J Community Nurs. 2024 May 2;29(5):224-230. doi: 10.12968/bjcn.2024.29.5.224.ABSTRACTBACKGROUND: Remote monitoring technologies show potential to help health professionals deliver preventative interventions which can avoid hospital...

Artificial Intelligence

4 May 2024

Heart Sound Abnormality Detection From Multi-Institutional Collaboration: Introducing a Federated Learning Framework

IEEE Trans Biomed Eng. 2024 May 3;PP. doi: 10.1109/TBME.2024.3393557. Online ahead of print.ABSTRACTOBJECTIVE: Early diagnosis of cardiovascular diseases is a crucial task in medical practice....

Psychiatry

4 May 2024

Patent Foramen Ovale Closure in Older Patients With Stroke: Patient Selection for Trial Feasibility

Neurology. 2024 May 28;102(10):e209388. doi: 10.1212/WNL.0000000000209388. Epub 2024 May 3.ABSTRACTBACKGROUND AND OBJECTIVES: Whether patent foramen ovale (PFO) closure benefits older patients with PFO and cryptogenic...

Psychiatry

4 May 2024

Bilingualism Predicts Affective Theory of Mind in Autistic Adults

J Speech Lang Hear Res. 2024 May 3:1-18. doi: 10.1044/2024_JSLHR-23-00431. Online ahead of print.ABSTRACTPURPOSE: This study examined the impact of bilingualism on affective theory of...

Psychiatry

4 May 2024

Exploring the Interactions between two Ligands, UCB-J and UCB-F, and Synaptic Vesicle Glycoprotein 2 Isoforms

ACS Chem Neurosci. 2024 May 3. doi: 10.1021/acschemneuro.4c00029. Online ahead of print.ABSTRACTIn silico modeling was applied to study the efficiency of two ligands, namely, UCB-J...

Psychiatry

4 May 2024

The Synergistic Impact of Probiotics and Dietary Fiber on Constipation Management in Chlorpromazine-Induced Schizophrenia Patients: Exploring the Modulation of Intestinal Microbiota and Neurotrophic Factors

Int J Neurosci. 2024 May 3:1-10. doi: 10.1080/00207454.2024.2352023. Online ahead of print.ABSTRACTObjective: To explore the improvement effect of probiotics combined with dietary fiber on constipation...

Psychiatry

4 May 2024

Hippocampal excitation-inhibition balance underlies the 5-HT2C receptor in modulating depressive behaviours

Brain. 2024 May 3:awae143. doi: 10.1093/brain/awae143. Online ahead of print.ABSTRACTThe implication of 5-hydroxytryptamine 2C receptor (5-HT2CR) in depression is a topic of debate, and the...

Psychiatry

4 May 2024

Connectome reorganization associated with temporal lobe pathology and its surgical resection

Brain. 2024 May 3:awae141. doi: 10.1093/brain/awae141. Online ahead of print.ABSTRACTNetwork neuroscience offers a unique framework to understand the organizational principles of the human brain. Despite...

Psychiatry

4 May 2024

Primary care clinic visits in formerly evacuated areas due to radiation disaster following the Great East Japan Earthquake: A retrospective descriptive study

Medicine (Baltimore). 2024 May 3;103(18):e37942. doi: 10.1097/MD.0000000000037942.ABSTRACTRadiation disasters pose distinctive medical challenges, requiring diverse care approaches. Beyond radiation exposure assessment, addressing health impacts due to...

Psychiatry

4 May 2024

Liraglutide-associated depression in a patient with type 2 diabetes: A case report and discussion

Medicine (Baltimore). 2024 May 3;103(18):e37928. doi: 10.1097/MD.0000000000037928.ABSTRACTBACKGROUND: Glucagon-like peptide-1 receptor agonists (GLP-1RAs) like liraglutide are primarily used for managing blood sugar levels in type 2...

Psychiatry

4 May 2024

Belief Updating, Childhood Maltreatment, and Paranoia in Schizophrenia-Spectrum Disorders

Schizophr Bull. 2024 May 3:sbae057. doi: 10.1093/schbul/sbae057. Online ahead of print.ABSTRACTBACKGROUND AND HYPOTHESIS: Exposure to childhood maltreatment-a risk factor for psychosis is associated with paranoia-may...

Psychiatry

4 May 2024

Update of the World Health Organization’s Mental Health Gap Action Programme Guideline for Psychoses (Including Schizophrenia)

Schizophr Bull. 2024 May 3:sbae043. doi: 10.1093/schbul/sbae043. Online ahead of print.ABSTRACTBACKGROUND AND HYPOTHESIS: The World Health Organization's (WHOs) Mental Health Gap Action Programme (mhGAP) aims...

Medicine

4 May 2024

Pediatric to Adult Transition in Inflammatory Bowel Disease: Consensus Guidelines for Australia and New Zealand

Inflamm Bowel Dis. 2024 May 3:izae087. doi: 10.1093/ibd/izae087. Online ahead of print.ABSTRACTBACKGROUND: The incidence of pediatric inflammatory bowel disease (IBD) is rising, and there is...

Medicine

4 May 2024

Osteoclasts Link Dysregulated Peripheral Degradation Processes and Accelerated Progression in Alzheimer’s Disease

J Alzheimers Dis. 2024 Apr 29. doi: 10.3233/JAD-240096. Online ahead of print.ABSTRACTBACKGROUND: The amyloid-β (Aβ) enhances the number and activity of blood monocyte-derived osteoclasts (OCs)....

Medicine

4 May 2024

Prevalence and characteristics of smoking cigarette and narghile among Syrian refugee parents in Ontario, Canada

PLOS Glob Public Health. 2024 May 3;4(5):e0003176. doi: 10.1371/journal.pgph.0003176. eCollection 2024.ABSTRACTThis study aimed to explore the prevalence and associated sociodemographic, migration, and health-related factors of...