Medicine (Baltimore). 2024 Apr 5;103(14):e37730. doi: 10.1097/MD.0000000000037730.

ABSTRACT

RATIONALE: Turner syndrome (TS) is a genetic disorder associated with partial or complete monosomy X abnormalities; some patients may have a higher risk of psychiatric symptoms. Catatonia is associated with a wide range of life-threatening complications with complex pathogenesis; However, It very rare for patients with TS to develop psychotic symptoms and eventually progress to catatonia. This case report describes the diagnostic and therapeutic course of catatonia-associated TS.

PATIENT CONCERNS: In this study, we report the case of a patient with TS who initially developed sudden hallucinations, delusions, and emotional instability, followed by catatonia.

DIAGNOSES: The patient was diagnosed with: unspecified catatonia; TS.

INTERVENTIONS: Treatment included administering a combination of esazolam injections and olanzapine tablets, placing a gastric tube and urinary catheter, and providing nutritional support.

OUTCOMES: After treatment, the patient’s hallucinations, delusions, and catatonia disappeared, with no residual sequelae, and social functioning returned to normal.

LESSONS: For patients with TS who present with psychotic symptoms and catatonia, a comprehensive evaluation is necessary, and treatment with antipsychotics and benzodiazepines is effective.

PMID:38579062 | DOI:10.1097/MD.0000000000037730