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Akathisia and oculogyric crisis in hyperemesis gravidarum

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Obstet Med. 2024 Jun;17(2):129-131. doi: 10.1177/1753495X221137942. Epub 2022 Nov 13.

ABSTRACT

Hyperemesis gravidarum complicates 0.5-2% of pregnancies. HG is associated with insomnia, significantly increased risks of anxiety and depression, and may be associated with feelings of guilt, social isolation and thoughts of suicidal ideation or termination of pregnancy. Anti-emetic therapy may be complicated by akathisia and dystonic reactions, which may affect the ongoing management of nausea and vomiting. A case of akathisia and oculogyric crisis following the addition of parenteral prochlorperazine to ondansetron and metoclopramide is presented. The treatment options for extrapyramidal side effects with anti-emetics in pregnancy and for ongoing treatment of nausea and vomiting are discussed.

PMID:38784181 | PMC:PMC11110745 | DOI:10.1177/1753495X221137942

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