Evidence
![](https://psychiatryai.com/wp-content/uploads/2023/04/psychiatryai_com.webp)
Nat Sci Sleep. 2024 Apr 16;16:389-400. doi: 10.2147/NSS.S452517. eCollection 2024.
ABSTRACT
PURPOSE: Postoperative sleep disturbance, characterized by diminished postoperative sleep quality, is a risk factor for postoperative delirium (POD); however, the association between pre-existing sleep disturbance and POD remains unclear. This study aimed to evaluate the association between preoperative sleep disturbance and POD in elderly patients after non-cardiac surgery.
PATIENTS AND METHODS: This retrospective cohort study was conducted at a single center and enrolled 489 elderly patients who underwent surgery between May 1, 2020, and March 31, 2021. Patients were divided into the sleep disorder (SD) and non-sleep disorder (NSD) groups according to the occurrence of one or more symptoms of insomnia within one month or sleep- Numerical Rating Scale (NRS)≥6 before surgery. The primary outcome was the incidence of POD. Propensity score matching analysis was performed between the two groups. Multiple logistic regression analysis was performed to identify the risk factors for POD.
RESULTS: In both the unmatched cohort (16.0% vs 6.7%, P=0.003) and the matched cohort (17.0% vs 6.2%, P=0.023), the incidence of POD was higher in the SD group than in the NSD group. In addition, the postoperative sleep quality and the VAS score at postoperative 24 h were significantly lower in the SD group than in the NSD group. Multivariate logistic regression analysis indicated that age (Odds Ratio, 1.13 [95% CI: 1.04-1.23], P=0.003) and preoperative sleep disturbance (Odds Ratio, 3.03 [95% CI: 1.09-9.52], P=0.034) were independent risk factors for the development of POD.
CONCLUSION: The incidence of POD was higher in patients with pre-existing sleep disturbance than those without it. Whether improving sleep quality for preoperative sleep disturbance may help prevent POD remains to be determined.
PMID:38646462 | PMC:PMC11032121 | DOI:10.2147/NSS.S452517
![Google](https://www.google.com/images/branding/googlelogo/2x/googlelogo_light_color_92x30dp.png)
![Google Keep](https://www.gstatic.com/images/branding/product/1x/keep_48dp.png)
![Share on Linkedin](https://psychiatryai.com/wp-content/uploads/2023/10/linkedin-logo-png-2048-1.png)
Estimated reading time: 5 minute(s)
Latest: Psychiatryai.com #RAISR4D Evidence
![](/wp-content/uploads/2024/04/bd462cc11bcf0bd0d0d6f1d0f8b7cd04-modified-1.png)
Cool Evidence: Engaging Young People and Students in Real-World Evidence
![](/wp-content/uploads/2024/04/bd462cc11bcf0bd0d0d6f1d0f8b7cd04-modified-1.png)
Real-Time Evidence Search [Psychiatry]
![](/wp-content/uploads/2024/04/pubmed.png)
AI Research
![](/wp-content/uploads/2024/05/Il5nR_nf_400x400-modified-1.png)
Association Between Preoperative Sleep Disturbance and Postoperative Delirium in Elderly: A Retrospective Cohort Study
![](https://psychiatryai.com/wp-content/uploads/2023/04/psychiatryai_com.webp)
🌐 90 Days
AI Virtual Reality Related Evidence Matrix
Effects of Chinese traditional five-element music intervention on postoperative delirium and sleep quality in elderly patients after non-cardiac surgery: a randomized controlled trial Effects of Intranasal Insulin Pretreatment on Preoperative Sleep Quality and Postoperative Delirium in Patients Undergoing Valve Replacement for Rheumatic Heart Disease Association of preoperative neutrophil-to-lymphocyte ratio with the risk of postoperative delirium in elderly patients undergoing noncardiac surgery: a systematic review and meta-analysis Study on the preventive effect of dexmedetomidine on anesthetic associated sleep disturbance in young to middle-aged female patients undergoing hysteroscopy: a study protocol for a crossover randomized controlled trial Study on the preventive effect of dexmedetomidine on anesthetic associated sleep disturbance in young to middle-aged female patients undergoing hysteroscopy: a study protocol for a crossover randomized controlled trial Postoperative use of sleep aids and delirium in older adults after major surgery: A retrospective cohort study Preoperative cognitive function as a risk factor of postoperative delirium in cancer surgeries: A systematic review and meta-analysis Association of postoperative delirium with hypotension in critically ill patients after cardiac surgery: a prospective observational study Association of postoperative delirium with hypotension in critically ill patients after cardiac surgery: a prospective observational study Predictive value of the Naples prognostic score on postoperative delirium in the elderly with gastrointestinal tumors: a retrospective cohort study COVID-19 vaccination may prevent postoperative delirium in elderly patients undergoing elective non-cardiac surgery: The PNDRFAP and PNDABLE studies Postoperative delirium risk in patients with hyperlipidemia: A prospective cohort study Extracellular Vesicle MicroRNAs as Predictive Biomarkers in Postoperative Delirium after Spine Surgery; Preliminary Study Preoperative cognitive performance and its association with postoperative complications in vascular surgery patients: A prospective study Preoperative cognitive performance and its association with postoperative complications in vascular surgery patients: A prospective study The association between intraoperative hypotension and postoperative delirium- a retrospective cohort analysis Association between modified frailty index and postoperative delirium in patients after cardiac surgery: A cohort study of 2080 older adults Effect of phenylephrine versus ephedrine on the incidence of postoperative delirium in olderly adults undergoing knee arthroplasty under general anesthesia: a single-center trial Predictiveness of preoperative laboratory values for postoperative delirium Predictiveness of preoperative laboratory values for postoperative delirium An in-depth analysis of postoperative insomnia in elderly patients and its implications on rehabilitation Association between postoperative hyperactive delirium and major complications in elderly patients undergoing emergency hip fracture surgery: A large-scale cohort study Hemoglobin level, degree of mobilization, and pneumonia are associated with the development of postoperative delirium in cemented hemiarthroplasty after femoral neck fracture A Novel Preoperative Electroencephalogram-Derived Index to Predict Early Postoperative Delirium in Elderly Patients After Hip Fracture Surgeries: Development of a Prediction Model Analysis of risk factors for postoperative delirium in elderly patients undergoing spinal surgery Examining the impact of permissibility hypercapnia on postoperative delirium among elderly patients undergoing thoracoscopic-laparoscopic esophagectomy: A single-center investigative study Adverse postoperative outcomes in elderly patients with sarcopenia Association between pediatric postoperative delirium and regional cerebral oxygen saturation: a prospective observational study Prevalence and risk factors of postoperative delirium in tumor patients after free flap reconstruction: A systematic review and meta-analysis of case-control studies Postoperative delirium in oral and maxillofacial surgery: a scoping review Role of Intraoperative Electroencephalography in Predicting Postoperative Delirium in Patients Undergoing Cardiovascular Surgeries The bispectral electroencephalography (BSEEG) method quantifies post-operative delirium-like states in young and aged male mice after head mount implantation surgery The relationship between intraoperative hypothermia and postoperative delirium: The PNDRFAP study Electroencephalographic Measures of Delirium in the Perioperative Setting: A Systematic Review Bibliometric Analysis of the Top-100 Cited Articles on Postoperative Delirium The Genome-wide DNA methylation changes in gastrointestinal surgery patients with and without postoperative delirium: Evidence of immune process in its pathophysiology Establishment and validation of the prediction model for postoperative delirium risk factors in older patients after total knee arthroplasty: A retrospective study Predicting the Risk of Postoperative Delirium in Elderly Patients Undergoing Hip Arthroplasty: Development and Assessment of a Novel Nomogram Moderation by better sleep of the association among childhood maltreatment, neuroticism, and depressive symptoms in the adult volunteers: A moderated mediation model The influence of low-dose s-ketamine on postoperative delirium and cognitive function in older adults undergoing thoracic surgery Role of oral melatonin in prevention of postoperative delirium in patients undergoing elective surgery under general anesthesia: A Randomized controlled trial Incidence and risk factors of postoperative delirium following hepatic resection: a retrospective national inpatient sample database study Incidence and risk factors of postoperative delirium following hepatic resection: a retrospective national inpatient sample database study Incidence of Postoperative Delirium among Elderly Patients after Elective Surgeries under Anesthesia in the Charity Services of the Philippine General Hospital Development of an individualized model for predicting postoperative delirium in elderly patients with hepatocellular carcinoma The relationship between sleep disturbance and aggressive behaviour among community-dwelling schizophrenia patients: a moderated mesomeric effect model Risk Factors for Postoperative Delirium Severity After Deep Brain Stimulation Surgery in Parkinson's Disease Predicting postoperative delirium after percutaneous transluminal angioplasty and stenting in patients with intracranial atherosclerotic stenosis A first assessment of the safe brain initiative care bundle for addressing postoperative delirium in the postanesthesia care unit Outcomes associated with postoperative cognitive dysfunction: a systematic review and meta-analysis Outcomes associated with postoperative cognitive dysfunction: a systematic review and meta-analysis Electroencephalography Monitoring for Preventing Postoperative Delirium and Postoperative Cognitive Decline in Patients Undergoing Cardiothoracic Surgery: A Meta-Analysis Poor Self-Reported Sleep is Associated with Prolonged White Matter T2 Relaxation in Psychotic Disorders Potential mechanism of Taohong Siwu Decoction in preventing and treating postoperative delirium in intertrochanteric fracture patients based on retrospective analysis and network pharmacology Development and validation of a nomogram to predict postoperative delirium in older patients after major abdominal surgery: a retrospective case-control study Global Research Trends in Postoperative Delirium and Its Risk Factors: A Bibliometric and Visual Analysis Infants' early recovery from sleep disturbance is associated with a lower risk of developmental delay in the Japan Environment and Children's Study Delirium management in perioperative geriatric services: a narrative review of non-pharmaceutical strategies Delirium management in perioperative geriatric services: a narrative review of non-pharmaceutical strategies Incidence and related risk factors for postoperative delirium following revision total knee arthroplasty: a retrospective nationwide inpatient sample database study Incidence and Risk Factors for Hyponatremia in Postoperative Spinal Surgery Patients Clinical and video-polysomnographic characterization of restless sleep disorder in adult patients Autism-associated neuroligin-3 deficiency in medial septum causes social deficits and sleep loss in mice Autism-associated neuroligin-3 deficiency in medial septum causes social deficits and sleep loss in mice
Evidence Blueprint
Association Between Preoperative Sleep Disturbance and Postoperative Delirium in Elderly: A Retrospective Cohort Study
![](https://psychiatryai.com/wp-content/uploads/2023/04/psychiatryai_com.webp)
☊ AI-Driven Related Evidence Nodes
(recent articles with at least 5 words in title)
More Evidence
![](https://psychiatryai.com/wp-content/uploads/2023/04/psychiatryai_com.webp)
Association Between Preoperative Sleep Disturbance and Postoperative Delirium in Elderly: A Retrospective Cohort Study
🌐 365 Days
AI Virtual Reality Related Evidence Matrix
Association Between Preoperative Long-Term Poor Sleep Quality and Postoperative Delirium in Elderly Patients Undergoing Cardiac Surgery: A Multi-Center Observational Study Effects of Chinese traditional five-element music intervention on postoperative delirium and sleep quality in elderly patients after non-cardiac surgery: a randomized controlled trial Effects of Intranasal Insulin Pretreatment on Preoperative Sleep Quality and Postoperative Delirium in Patients Undergoing Valve Replacement for Rheumatic Heart Disease Association of preoperative neutrophil-to-lymphocyte ratio with the risk of postoperative delirium in elderly patients undergoing noncardiac surgery: a systematic review and meta-analysis Analysis of Changes in Sleep Quality and Patterns after Hip Fracture Using Real Evidence of Artificial Intelligence Linked (REAL) Hip Cohort Data Study on the preventive effect of dexmedetomidine on anesthetic associated sleep disturbance in young to middle-aged female patients undergoing hysteroscopy: a study protocol for a crossover randomized controlled trial Study on the preventive effect of dexmedetomidine on anesthetic associated sleep disturbance in young to middle-aged female patients undergoing hysteroscopy: a study protocol for a crossover randomized controlled trial The Association of Preoperative Diabetes With Postoperative Delirium in Older Patients Undergoing Major Orthopedic Surgery: A Prospective Matched Cohort Study Postoperative use of sleep aids and delirium in older adults after major surgery: A retrospective cohort study Preoperative cognitive function as a risk factor of postoperative delirium in cancer surgeries: A systematic review and meta-analysis Association of postoperative delirium with hypotension in critically ill patients after cardiac surgery: a prospective observational study Association of postoperative delirium with hypotension in critically ill patients after cardiac surgery: a prospective observational study Predictive value of the Naples prognostic score on postoperative delirium in the elderly with gastrointestinal tumors: a retrospective cohort study Triglyceride-glucose index predicts postoperative delirium in elderly patients with type 2 diabetes mellitus: a retrospective cohort study COVID-19 vaccination may prevent postoperative delirium in elderly patients undergoing elective non-cardiac surgery: The PNDRFAP and PNDABLE studies Nomogram for predicting the risk of postoperative delirium in elderly patients undergoing orthopedic surgery Postoperative delirium risk in patients with hyperlipidemia: A prospective cohort study The association between the fibrinogen-to-albumin ratio and delirium after deep brain stimulation surgery in Parkinson's disease Extracellular Vesicle MicroRNAs as Predictive Biomarkers in Postoperative Delirium after Spine Surgery; Preliminary Study Preoperative cognitive performance and its association with postoperative complications in vascular surgery patients: A prospective study Preoperative cognitive performance and its association with postoperative complications in vascular surgery patients: A prospective study The association between intraoperative hypotension and postoperative delirium- a retrospective cohort analysis Association between modified frailty index and postoperative delirium in patients after cardiac surgery: A cohort study of 2080 older adults Resting-state functional connectivity changes in older adults with sleep disturbance and the role of amyloid burden Impact of intraoperative dexmedetomidine on postoperative delirium and pro-inflammatory cytokine levels in elderly patients undergoing thoracolumbar compression fracture surgery: A prospective, randomized, placebo-controlled clinical trial Effect of phenylephrine versus ephedrine on the incidence of postoperative delirium in olderly adults undergoing knee arthroplasty under general anesthesia: a single-center trial Updated ESAIC guidelines on postoperative delirium in adults Predictiveness of preoperative laboratory values for postoperative delirium Predictiveness of preoperative laboratory values for postoperative delirium Unraveling the Predictors for Delirium and ICU Stay Duration in Patients with Heart Failure and Reduced Ejection Fraction (HFrEF) Undergoing Coronary Artery Bypass Grafting-A Multicentric Analysis Associations between postoperative cognitive dysfunction, serum interleukin-6 and postoperative delirium among patients after coronary artery bypass grafting: A mediation analysis Evaluating the effects of S-ketamine on postoperative delirium in elderly patients following total hip or knee arthroplasty under intraspinal anesthesia: a single-center randomized, double-blind, placebo-controlled, pragmatic study protocol Serum NPTX2 as a Potential Predictive Biomarker for Postoperative Delirium in Patients with Acute Type A Aortic Dissection An in-depth analysis of postoperative insomnia in elderly patients and its implications on rehabilitation Feasibility and Acceptability of Using Wireless Limited Polysomnography to Capture Sleep Before, During, and After Hospitalization for Patients With Planned Cardiothoracic Surgery Association between increased systemic immune-inflammation index and postoperative delirium in older intertrochanteric fracture patients Objective sleep disturbance in nightmares: Is prolonged sleep onset latency a proxy for fear-of-sleep-related arousal? Development and validation of a new drug-focused predictive risk score for postoperative delirium in orthopaedic and trauma surgery patients Related factors of delirium after transsphenoidal endoscopic pituitary adenoma resection-A matched retrospective cohort study Association between postoperative hyperactive delirium and major complications in elderly patients undergoing emergency hip fracture surgery: A large-scale cohort study Prevalence and influencing factors of sleep disturbance among medical students under the COVID-19 pandemic Hemoglobin level, degree of mobilization, and pneumonia are associated with the development of postoperative delirium in cemented hemiarthroplasty after femoral neck fracture Sleep disturbance and suicidal ideation mediated by psychotic-like experiences in adolescents: a two-wave longitudinal study A Novel Preoperative Electroencephalogram-Derived Index to Predict Early Postoperative Delirium in Elderly Patients After Hip Fracture Surgeries: Development of a Prediction Model Analysis of risk factors for postoperative delirium in elderly patients undergoing spinal surgery Examining the impact of permissibility hypercapnia on postoperative delirium among elderly patients undergoing thoracoscopic-laparoscopic esophagectomy: A single-center investigative study Depression and anxiety as mediators of the relationship between sleep disturbance and somatic symptoms among adolescents on a psychiatric inpatient unit Potential value of serum prealbumin and serum albumin in the identification of postoperative delirium in patients undergoing knee/hip replacement: an observational study and internal validation study Adverse postoperative outcomes in elderly patients with sarcopenia Association between pediatric postoperative delirium and regional cerebral oxygen saturation: a prospective observational study Prevalence and risk factors of postoperative delirium in tumor patients after free flap reconstruction: A systematic review and meta-analysis of case-control studies Postoperative delirium in oral and maxillofacial surgery: a scoping review Efficacy and safety of perioperative melatonin for postoperative delirium in patients undergoing surgery: a systematic review and meta-analysis Adverse Childhood Events and Chronic Pain in Adolescents: The Role of Sleep Disturbance Factors associated with sleep disturbances in children and adolescents with Angelman Syndrome Predictive modeling for postoperative delirium in elderly patients with abdominal malignancies using synthetic minority oversampling technique Role of Intraoperative Electroencephalography in Predicting Postoperative Delirium in Patients Undergoing Cardiovascular Surgeries The bispectral electroencephalography (BSEEG) method quantifies post-operative delirium-like states in young and aged male mice after head mount implantation surgery The relationship between intraoperative hypothermia and postoperative delirium: The PNDRFAP study The dynamic responses of mood and sleep physiology to chronic sleep restriction and subsequent recovery sleep Preoperative ketamine administration for prevention of postoperative neurocognitive disorders after major orthopedic surgery in elderly patients: A multicenter randomized blinded placebo-controlled trial Sleep Disturbance during Post-Traumatic Amnesia and Early Recovery following Traumatic Brain Injury Problematic smartphone use and sleep disturbance: the roles of metacognitions, desire thinking, and emotion regulation Comparison of Remimazolam and Propofol on Postoperative Delirium in Elderly Patients Undergoing Radical Resection of Colon Cancer: A Single-Center Prospective Randomized Controlled Study