Evidence
Front Pharmacol. 2024 Apr 17;15:1372110. doi: 10.3389/fphar.2024.1372110. eCollection 2024.
ABSTRACT
Prevalent neurological disorders such as Alzheimer’s disease, Parkinson’s disease, and stroke are increasingly becoming a global burden as society ages. It is well-known that degeneration and loss of neurons are the fundamental underlying processes, but there are still no effective therapies for these neurological diseases. In recent years, plenty of studies have focused on the pharmacology and feasibility of natural products as new strategies for the development of drugs that target neurological disorders. Antrodia camphorata has become one of the most promising candidates, and the crude extracts and some active metabolites of it have been reported to play various pharmacological activities to alleviate neurological symptoms at cellular and molecular levels. This review highlights the current evidence of Antrodia camphorata against neurological disorders, including safety evaluation, metabolism, blood-brain barrier penetration, neuroprotective activities, and the potential on regulating the gut-microbiome-brain axis. Furthermore, potential strategies to resolve problematic issues identified in previous studies are also discussed. We aim to provide an overview for the ongoing development and utilization of Antrodia camphorata in cerebral neuropathology.
PMID:38694913 | PMC:PMC11061445 | DOI:10.3389/fphar.2024.1372110
Add to Google Keep
Estimated reading time: 4 minute(s)
Latest: Psychiatryai.com #RAISR4D
Cool Evidence: Engaging Young People and Students in Real-World Evidence ☀️
Real-Time Evidence Search [Psychiatry]
AI Research [Andisearch.com]
Current and further outlook on the protective potential of Antrodia camphorata against neurological disorders
🌐 90 Days
Evidence Blueprint
Current and further outlook on the protective potential of Antrodia camphorata against neurological disorders
☊ AI-Driven Related Evidence Nodes
(recent articles with at least 5 words in title)
More Evidence