Identifying Exploratory Physical Activity Thresholds Associated With Symptom Severity in Older Adults With Parkinson’s Disease
AI Summary
Quadratic regression of PASE scores identified minimum and optimal thresholds of 150 and 245 respectively for motor, nonmotor, and depressive symptoms.
Meeting minimum PASE threshold (150) linked to lower odds of hypertension 21.1%, diabetes 40.6%, and mild cognitive impairment 57.9% (p < .01).
Findings offer evidence-based exploratory PA thresholds to inform future research and clinical guidance on activity patterns in older adults with Parkinson's disease.
Adapt Phys Activ Q. 2026 Nov 13:1-9. doi: 10.1123/apaq.2025-0165. Online ahead of print.
ABSTRACT
This research identified exploratory physical activity (PA) thresholds associated with symptom severity in older adults with Parkinson’s disease and assessed their association with cardiometabolic and cognitive health. Data were collected from 3,259 participants (age: 65.64 ± 10.37) in the Fox Insight database. PA was measured using Physical Activity Scale for the Elderly. Quadratic regression identified exploratory PA thresholds for managing motor, nonmotor, and depressive symptoms, with minimum thresholds based on literature-defined cut points and optimal thresholds based on symptom plateaus. Logistic regression assessed relationship between these thresholds and prevalence of hypertension, diabetes, and mild cognitive impairment. Analyses identified exploratory minimum and optimal Physical Activity Scale for the Elderly threshold of 150 and 245. Meeting minimum PA threshold was associated with lower odds of hypertension (21.1%), diabetes (40.6%), and mild cognitive impairment (57.9%; p < .01). These findings provide evidence-based exploratory PA thresholds to guide future research on PA patterns in older adults with Parkinson’s disease.
Pain Manag Nurs. 2026 Nov 14:S1524-9042(26)00326-7. doi: 10.1016/j.pmn.2026.10.007. Online ahead of print.ABSTRACTINTRODUCTION: In long term care [LTC], the high prevalence of painful illnesses and dementia...
Rev Esp Anestesiol Reanim (Engl Ed). 2026 Nov 14:502232. doi: 10.1016/j.redare.2026.502232. Online ahead of print.ABSTRACTBACKGROUND: Ultrasound-guided regional anaesthesia in hip surgery has been shown to...
J Dent. 2026 Nov 14:107172. doi: 10.1016/j.jdent.2026.107172. Online ahead of print.ABSTRACTOBJECTIVES: Oral hypofunction is classified as an intermediate stage between oral frailty and oral dysfunction,...
Brain Res Bull. 2026 Nov 14:112220. doi: 10.1016/j.brainresbull.2026.112220. Online ahead of print.ABSTRACTBACKGROUND: Cognitive impairment is common in late-onset epilepsy of unknown etiology (LOEU), but its...
Anaesth Crit Care Pain Med. 2026 Nov 14:101991. doi: 10.1016/j.accpm.2026.101991. Online ahead of print.ABSTRACTBACKGROUND: Acute pain in the postoperative period and pre-existing cognitive impairment (CI)...
Brain Struct Funct. 2026 Nov 14;231(9):170. doi: 10.1007/s00429-026-03224-3.ABSTRACTFixel-based analysis (FBA) resolves fiber-specific white matter properties within crossing-fiber regions, where conventional diffusion tensor imaging is limited....
