Evidence
Biol Psychiatry Glob Open Sci. 2023 Dec 30;4(2):100283. doi: 10.1016/j.bpsgos.2023.100283. eCollection 2024 Mar.
ABSTRACT
There are prominent sex/gender differences in the prevalence, expression, and life span course of mental health and neurodiverse conditions. However, the underlying sex- and gender-related mechanisms and their interactions are still not fully understood. This lack of knowledge has harmful consequences for those with mental health problems. Therefore, we set up a cocreation session in a 1-week workshop with a multidisciplinary team of 25 researchers, clinicians, and policy makers to identify the main barriers in sex and gender research in the neuroscience of mental health. Based on this work, here we provide recommendations for methodologies, translational research, and stakeholder involvement. These include guidelines for recording, reporting, analysis beyond binary groups, and open science. Improved understanding of sex- and gender-related mechanisms in neuroscience may benefit public health because this is an important step toward precision medicine and may function as an archetype for studying diversity.
PMID:38312851 | PMC:PMC10837069 | DOI:10.1016/j.bpsgos.2023.100283
Add to Google Keep
Estimated reading time: 3 minute(s)
Latest: Psychiatryai.com #RAISR4D
Cool Evidence: Engaging Young People and Students in Real-World Evidence ☀️
Real-Time Evidence Search [Psychiatry]
AI Research [Andisearch.com]
Recommendations for a Better Understanding of Sex and Gender in the Neuroscience of Mental Health
🌐 90 Days
VR Related Evidence Matrix
- Gender, assigned sex at birth, and gender diversity: Windows into diagnostic timing disparities in autism
- Polygenic Scores Clarify the Relationship Between Mental Health and Gender Diversity
- Higher risk-less data: A systematic review and meta-analysis on the role of sex and gender in trauma research
- Gender, sex and complex PTSD clinical presentation: a systematic review
- Sex and gender publications in brain health: a mapping review of the Asia-Pacific region
- Opinion & Special Article: Community Approach Toward Inclusion of Sex and Gender Diversity in Graduate Neurology Education
- Treating sex and gender differences as a continuous variable can improve precision cancer treatments
- Do school and equality education characteristics influence young children's understanding of sex/gender constancy?
- How social is social media for transgender and gender-diverse youth? Association of online social experiences with internalizing mental health problems
- Research in brief: How prevalent is rough sex? Results from a national online sample of adults in Germany
- 'Nothing About Us, Without Us': Research Priorities for Autistic Girls, Women and Gender Diverse People in Australia
- Autism and sexual and gender minority identity in college students: Examination of self-reported rates, functional outcomes, and treatment engagement
- Brain characteristics of transgender individuals and consequences of gender assignment treatment
- Brain characteristics of transgender individuals and consequences of gender assignment treatment
- Identifying protective factors for gender diverse adolescents' mental health
- “Inequalities in mental health: economic and policy perspectives” OMHEP workshop
- Recommendations for the assessment of sexual and gender minority status in serious mental illness research and clinical care
- Gender diversity in autistic and neurotypical youth over adolescence and puberty: A longitudinal study
- Inequality on the frontline: A multi-country study on gender differences in mental health among healthcare workers during the COVID-19 pandemic
- A systematic meta-epidemiologic review on nonabstinence-inclusive interventions for substance use: inclusion of race/ethnicity and sex assigned at birth/gender
- An Exploratory Study of Sexual Aggression Tactics as a Function of Perpetrator Gender and Victim Gender
- The association between gender identity fluidity and health outcomes in transgender and gender diverse people in New Orleans and Los Angeles, USA
- Understanding the Role of Empathy and Gender on EMS Clinician Occupational Stress and Mental Health Outcomes
- Qualitative evaluation of an edutainment intervention to prevent age-disparate transactional sex in Tanzania: Changes in educational aspirations and gender equitable attitudes towards work
- Prevalence and factors associated with psychological distress among key populations in Nigeria
- Chronotype changes after sex hormone use: A prospective cohort study in transgender users of gender-affirming hormones
- From classroom to life: Gender differences in the persistent effect of learning disabilities on adult depressive symptoms
- Disparities in Behaviors and Experiences Among Transgender and Cisgender High School Students - 18 U.S. States, 2021
- Gender-affirming treatment and mental health diagnoses in Danish transgender persons: a nationwide register-based cohort study
- Gender-affirming treatment and mental health diagnoses in Danish transgender persons: a nationwide register-based cohort study
- The Role of Psychiatry for Transgender and Gender Diverse Adults
- The Role of Psychiatry for Transgender and Gender Diverse Adults
- Perceived discrimination in health care in Germany- results of a population survey
- Safeguarding in adolescent mental health research: navigating dilemmas and developing procedures
- Estimate and needs of the transgender adult population: the SPoT study
- Sex-specific associations between sex hormones and clinical symptoms in late-life schizophrenia
- Characteristics of children and adolescents referred to specialist gender services: a systematic review
- Sex difference in the association between excessive daytime sleepiness and health-related quality of life in community-dwelling older adults: The Yilan study, Taiwan
- Challenges and opportunities for improving mental health care and preventing suicide among people living with HIV: Perspectives of mental health professionals in Tanzania
- Gender and non-communicable diseases in Mexico: a political mapping and stakeholder analysis
- Comorbidity and household income as mediators of gender inequalities in dementia risk: a real-world data population study
- Increasing mental health issues in college students from 2016-2019: Assessing the intersections of race/ethnicity and gender
- Gender-affirming care for the adolescent patient
- Session 3: Co-creation and stakeholder engagement for impact in an Agile Sprint (online webinar)
- Gender Dysphoria
- Sexual Minorities within Heterosexuality: Psychosocial Characteristics of and Attitudes toward the "Fourth Love" in China
- Gender Dysphoria
- Geographical variation in perceptions, attitudes and barriers to mental health care-seeking across the UK: a cross-sectional study
- Factors Associated with Adolescent Pregnancy in Sub-Saharan Africa during the COVID-19 Pandemic: A Review of Socioeconomic Influences and Essential Interventions
- The Effectiveness of GenerationPMTO During Sustained Implementation in the Public Mental Health System: A Single-Arm Open Trial Evaluation
- The Effectiveness of GenerationPMTO During Sustained Implementation in the Public Mental Health System: A Single-Arm Open Trial Evaluation
- Gender services for children and adolescents across the EU-15+ countries: an online survey
- Gender and Autism Program: A novel clinical service model for gender-diverse/transgender autistic youth and young adults
- Mechanisms underlying memory impairment induced by fructose
- Preferences for mHealth Intervention to Address Mental Health Challenges Among Men Who Have Sex With Men in Nepal: Qualitative Study
- Sex-specific associations between co-exposure to multiple metals and externalizing symptoms in adolescence and young adulthood
- Demographic and mental health profile of youth in a gender service: An African case series
- Cohort Effects on Tobacco Consumption and its Genetic and Environmental Variance Among Finnish Adults born between 1880-1957
- It's time for change: inequities and determinants of health-related quality of life among gender and sexually diverse young people in Australia
- Symptom Severity and Health Impacts of Functional Tic-Like Behaviors in Youth
- Risk factors and consequences of mental health problems in nurses: A scoping review of cohort studies
- The impact of informant-related characteristics including sex/gender on assessment of Alzheimer's disease symptoms and severity
- Secular trends in risk factors for adolescent anxiety and depression symptoms: the Young-HUNT studies 1995-2019, Norway
- The risk of psychosis for transgender individuals: a Dutch national cohort study
Evidence Blueprint
Recommendations for a Better Understanding of Sex and Gender in the Neuroscience of Mental Health
☊ AI-Driven Related Evidence Nodes
(recent articles with at least 5 words in title)
More Evidence
Recommendations for a Better Understanding of Sex and Gender in the Neuroscience of Mental Health
🌐 365 Days
VR Related Evidence Matrix
- Gender, assigned sex at birth, and gender diversity: Windows into diagnostic timing disparities in autism
- Polygenic Scores Clarify the Relationship Between Mental Health and Gender Diversity
- Sex/Gender Differences in Cognitive Abilities
- Why and How to Account for Sex and Gender in Brain and Behavioral Research
- Sex and gender in infection and immunity: addressing the bottlenecks from basic science to public health and clinical applications
- Higher risk-less data: A systematic review and meta-analysis on the role of sex and gender in trauma research
- Gender-Affirming Surgery Improves Mental Health Outcomes and Decreases Anti-Depressant Use in Patients with Gender Dysphoria
- Gender, sex and complex PTSD clinical presentation: a systematic review
- Are we moving the dial? Canadian health research funding trends for women's health, 2S/LGBTQ + health, sex, or gender considerations
- Gender-Affirming Medical Treatments
- Mental Health of Transgender Youth: A Comparison of Assigned Female at Birth and Assigned Male at Birth Individuals
- Considerations for Expanding Research and Clinical Care for the Neurodivergent Gender Diverse Population
- Considerations for Expanding Research and Clinical Care for the Neurodivergent Gender Diverse Population
- A step-by-step and data-driven guide to index gender in psychiatry
- Identifying Strategies for the Use of Gender and Sex Language in Clinical One-Liners
- Sex and gender publications in brain health: a mapping review of the Asia-Pacific region
- Opinion & Special Article: Community Approach Toward Inclusion of Sex and Gender Diversity in Graduate Neurology Education
- Treating sex and gender differences as a continuous variable can improve precision cancer treatments
- Care pathways for young transgender people
- Children and adolescents with gender questions: dilemmas in the hormonal treatment by multidisciplinary teams
- Do school and equality education characteristics influence young children's understanding of sex/gender constancy?
- Parental gender attitudes and children's mental health: Evidence from the UK household longitudinal study
- Doing and undoing transgender health care: The ordering of 'gender dysphoria' in clinical practice
- Demographic Differences in Gender Dysphoria Diagnosis and Access to Gender-Affirming Care Among Adolescents
- Association Between Peer Victimization, Gender Diversity, Mental Health, and Recurrent Headaches in Adolescents: A Canadian Population-Based Study
- Trends and the Gender Gap in the Reporting of Sexual Initiation Among 15-Year-Olds: A Comparison of 33 European Countries
- How social is social media for transgender and gender-diverse youth? Association of online social experiences with internalizing mental health problems
- Differential network interactions between psychosocial factors, mental health, and health-related quality of life in women and men
- Binary and Non-binary Gender Identities, Internalizing Problems, and Treatment Wishes Among Adolescents Referred to a Gender Identity Clinic in Germany
- Subjective Experiences of Pregnancy, Delivery, and Nursing in Transgender Men and Non-Binary Individuals: A Qualitative Analysis of Gender and Mental Health Concerns
- Patterns of gender identity data within electronic health record databases can be used as a tool for identifying and estimating the prevalence of gender-expansive people
- Gender-Affirming Mental Health Care for Transgender and Gender Diverse Youth on Pediatric Inpatient Psychiatry Units
- Navigating adolescence: pubertal development in autism spectrum conditions and its relation to mental health
- Short report: Recommendations for education, clinical practice, research, and policy on promoting well-being in autistic youth and adults through a positive focus on sexuality and gender diversity
- How gender and low mental health literacy are related to unmet need for mental healthcare: a cross-sectional population-based study in Sweden
- Research in brief: How prevalent is rough sex? Results from a national online sample of adults in Germany
- IDEA Group Consensus Statement on Medical Management of Adult Gender Incongruent Individuals Seeking Gender Affirmation as Male
- Talking About Sexuality with Youth: A Taboo in Psychiatry?
- Commentary: A commentary on "Don't mind the gap: Why we do not care about the gender gap in mental health?" by P. Patalay and O. Demkowicz
- Psychological disorders and positive mental health in gender-diverse youth
- 'Nothing About Us, Without Us': Research Priorities for Autistic Girls, Women and Gender Diverse People in Australia
- Gender Dysphoria in a Patient With Ovotesticular Disorder of Sex Development
- Limitations and Future Directions in Sex, Sexuality and Gender Diverse Research in Neurology
- Autism and sexual and gender minority identity in college students: Examination of self-reported rates, functional outcomes, and treatment engagement
- Brain characteristics of transgender individuals and consequences of gender assignment treatment
- Brain characteristics of transgender individuals and consequences of gender assignment treatment
- Identifying protective factors for gender diverse adolescents' mental health
- Gender differences in mental health outcomes among Afghanistan veterans exposed to war zone trauma
- “Inequalities in mental health: economic and policy perspectives” OMHEP workshop
- Gender diversity in autistic clients: an ethical perspective
- Emerging Subspecialties in Neurology: Women's Neurology
- Voices from a Multidisciplinary Healthcare Center: Understanding Barriers in Gender-Affirming Care-A Qualitative Exploration
- Gender and Sexual Health-Related Knowledge Gaps and Educational Needs of Parents of Transgender and Non-Binary Youth
- Recommendations for the assessment of sexual and gender minority status in serious mental illness research and clinical care
- Coping with Gender Dysphoria in a Rural Environment during Adolescence
- Extending Gender- and Sex-Based Analyses in Cannabis Research: Findings from an Online Sample of Gender Diverse Young Adult Consumers
- Gender diversity in autistic and neurotypical youth over adolescence and puberty: A longitudinal study
- Inequality on the frontline: A multi-country study on gender differences in mental health among healthcare workers during the COVID-19 pandemic
- Inequities in the treatment of opioid use disorder: A scoping review
- Impact of sex and gender on post-COVID-19 syndrome, Switzerland, 2020
- Molecular mechanisms of hormones implicated in migraine and the translational implication for transgender patients
- Substance Use Over Time Among Sexual and Gender Minority People: Differences at the Intersection of Sex and Gender
- Mixed-Methods Examination of Adolescent-Reported Barriers to Accessing Mental Health Services
- Associations Between Family History of Alcohol and/or Substance Use Problems and Frontal Cortical Development From 9 to 13 Years of Age: A Longitudinal Analysis of the ABCD Study