Evidence
Document this CPD
Add to Google Keep
Estimated reading time: 1 minute(s)
Latest: Psychiatryai.com #RAISR4D
Cool Evidence: Engaging Young People and Students in Real-World Evidence ☀️
Real-Time Evidence Search [Psychiatry]
AI Research [Andisearch.com]
Single-cell epigenetic analysis reveals principles of chromatin states in H3.3-K27M gliomas
🌐 90 Days
VR Related Evidence Matrix
- scENCORE: leveraging single-cell epigenetic data to predict chromatin conformation using graph embedding
- Insights from a Multicenter Study on Adult H3 K27M-Mutated Glioma: Surgical Resection's Limited Influence on Overall Survival, ATRX as Molecular Prognosticator
- Causal gene regulatory analysis with RNA velocity reveals an interplay between slow and fast transcription factors
- Novel protein-truncating variants of a chromatin-modifying gene MSL2 in syndromic neurodevelopmental disorders
- Variations in 3D genome structure between homologous chromosomes and in stimulus responses
- Variations in 3D genome structure between homologous chromosomes and in stimulus responses
- Small-molecule-induced epigenetic rejuvenation promotes SREBP condensation and overcomes barriers to CNS myelin regeneration
- Epigenetics of Genes Preferentially Expressed in Dissimilar Cell Populations: Myoblasts and Cerebellum
- The multifaceted functions of long non-coding RNA HOTAIR in neuropathologies and its potential as a prognostic marker and therapeutic biotarget
- The multifaceted functions of long non-coding RNA HOTAIR in neuropathologies and its potential as a prognostic marker and therapeutic biotarget
- Subpopulation commensalism promotes Rac1-dependent invasion of single cells via laminin-332
- Chromatin modifiers in human disease: from functional roles to regulatory mechanisms
- Pattern Recognition of Common Multiple Congenital Malformation Syndromes with Underlying Chromatinopathy
- Partial Reprogramming as a Method for Regenerating Neural Tissues in Aged Organisms
- Integrating single-cell and spatially resolved transcriptomic strategies to survey the astrocyte response to stroke in male mice
- Protocol to perform integrative analysis of high-dimensional single-cell multimodal data using an interpretable deep learning technique
- Metabolic models predict fotemustine and the combination of eflornithine/rifamycin and adapalene/cannabidiol for the treatment of gliomas
- Reduction of APOE accounts for neurobehavioral deficits in fetal alcohol spectrum disorders
- Reduction of APOE accounts for neurobehavioral deficits in fetal alcohol spectrum disorders
- Allele-Specific Regulation of the Candidate Autism Liability Gene RAI1 by the Enhancer Variant rs4925102 (C/G)
- Stem Cell Markers in Neoplasms and their Relationship with Progression-free and Overall Survival in Patients with Recurrence
- Connecting genomic results for psychiatric disorders to human brain cell types and regions reveals convergence with functional connectivity
- Integration analysis of cell division cycle-associated family genes revealed potential mechanisms of gliomagenesis and constructed an artificial intelligence-driven prognostic signature
- Early screening of colorectal cancer using feature engineering with artificial intelligence-enhanced analysis of nanoscale chromatin modifications
- Single-Cell Multi-Omics Map of Cell Type-Specific Mechanistic Drivers of Multiple Sclerosis Lesions
- Comparative Analysis of Single-Cell RNA Sequencing Methods with and without Sample Multiplexing
- Spermatogenesis: a paradigm of stem cell regulation
- Lithium response in bipolar disorder: Epigenome-wide DNA methylation signatures and epigenetic aging
- Prominent genetic variants and epigenetic changes in post-traumatic stress disorder among combat veterans
- Advancements in Single-Cell RNA Sequencing Research for Neurological Diseases
- Analysis and Visualization of Single-Cell Sequencing Data with Scanpy and MetaCell: A Tutorial
- Haploinsufficiency of phosphodiesterase 10A activates PI3K/AKT signaling independent of PTEN to induce an aggressive glioma phenotype
- Fully automated MR-based virtual biopsy of primary CNS lymphomas
- JAK-STAT signaling maintains homeostasis in T cells and macrophages
- A systematic analyses of different bioinformatics pipelines for genomic data and its impact on deep learning models for chromatin loop prediction
- Single-cell RNA-seq data analysis reveals functionally relevant biomarkers of early brain development and their regulatory footprints in human embryonic stem cells (hESCs)
- FinaleMe: Predicting DNA methylation by the fragmentation patterns of plasma cell-free DNA
- Shared inflammatory glial cell signature after stab wound injury, revealed by spatial, temporal, and cell-type-specific profiling of the murine cerebral cortex
- American Psychiatric Association Opposes Efforts to Ban Diversity, Equity and Inclusion Initiatives
- American Psychiatric Association Opposes Efforts to Ban Diversity, Equity and Inclusion Initiatives
- Oxford researchers launch updated carbon offsetting principles
- Zmiz1 is a novel regulator of brain development associated with autism and intellectual disability
- Single-cell dissection of the human motor and prefrontal cortices in ALS and FTLD
- Single-Cell Nuclear Sequencing Atlas Revealed the Induction of Parkinson's Disease by RELN+ Neuron 3 and the Gene Regulatory Network of MSRA
- Epigenetic mechanisms linking early-life adversities and mental health
- Characterizing dysregulations via cell-cell communications in Alzheimer's brains using single-cell transcriptomes
- Mesenchymal stem cells as therapeutic vehicles for glioma
- An update on susceptibility-weighted imaging in brain gliomas
- scRank infers drug-responsive cell types from untreated scRNA-seq data using a target-perturbed gene regulatory network
- A human neural crest model reveals the developmental impact of neuroblastoma-associated chromosomal aberrations
- Glioblastoma-instructed microglia transition to heterogeneous phenotypic states with phagocytic and dendritic cell-like features in patient tumors and patient-derived orthotopic xenografts
- Transcriptomics of Human Brain Tissue in Parkinson's Disease: a Comparison of Bulk and Single-cell RNA Sequencing
- AI ethics are ignoring children, say Oxford researchers
- Understanding and manipulating the T-cell response to peptide-MHC
- Postnatal epigenome-mediated aging control and global trends
- Glial Cell Development and Function in the Zebrafish Central Nervous System
- Variant-to-function analysis of the childhood obesity chr12q13 locus implicates rs7132908 as a causal variant within the 3' UTR of FAIM2
- Neuronal-specific methylome and hydroxymethylome analysis reveal significant loci associated with alcohol use disorder
- Neuronal-specific methylome and hydroxymethylome analysis reveal significant loci associated with alcohol use disorder
- Dynamic effective connectivity in the cerebellar dorsal dentate nucleus and the cerebrum, cognitive impairment, and clinical correlates in patients with schizophrenia
- GWAS meta-analysis reveals key risk loci in essential tremor pathogenesis
- ADNP dysregulates methylation and mitochondrial gene expression in the cerebellum of a Helsmoortel-Van der Aa syndrome autopsy case
- Epigenetic modification in liver fibrosis: Promising therapeutic direction with significant challenges ahead
- Identity and nature of neural stem cells in the adult human subventricular zone
Evidence Blueprint
Single-cell epigenetic analysis reveals principles of chromatin states in H3.3-K27M gliomas
☊ AI-Driven Related Evidence Nodes
(recent articles with at least 5 words in title)
More Evidence
Single-cell epigenetic analysis reveals principles of chromatin states in H3.3-K27M gliomas
🌐 365 Days
VR Related Evidence Matrix
- scENCORE: leveraging single-cell epigenetic data to predict chromatin conformation using graph embedding
- Dissecting the spatiotemporal diversity of adult neural stem cells
- Germ-cell-specific transcriptome analysis illuminates the chromatin and ubiquitin pathway in autism spectrum disorders
- DNA methylation in the mouse cochlea promotes maturation of supporting cells and contributes to the failure of hair cell regeneration
- macroH2A2 antagonizes epigenetic programs of stemness in glioblastoma
- Haploinsufficiency of NFKBIA reshapes the epigenome antipodal to the IDH mutation and imparts disease fate in diffuse gliomas
- Tumor heterogeneity and tumor-microglia interactions in primary and recurrent IDH1-mutant gliomas
- Mapping enhancer and chromatin accessibility landscapes charts the regulatory network of Alzheimer's disease
- Disruption of the autism gene and chromatin regulator KDM5A alters hippocampal cell identity
- Insights from a Multicenter Study on Adult H3 K27M-Mutated Glioma: Surgical Resection's Limited Influence on Overall Survival, ATRX as Molecular Prognosticator
- Slide-tags enables single-nucleus barcoding for multimodal spatial genomics
- Inferring cell-type-specific causal gene regulatory networks during human neurogenesis
- Inferring cell-type-specific causal gene regulatory networks during human neurogenesis
- Causal gene regulatory analysis with RNA velocity reveals an interplay between slow and fast transcription factors
- A new subtype of diffuse midline glioma, H3 K27 and BRAF/FGFR1 co-altered: a clinico-radiological and histomolecular characterisation
- MAPK inhibitor sensitivity scores predict sensitivity driven by the immune infiltration in pediatric low-grade gliomas
- Novel protein-truncating variants of a chromatin-modifying gene MSL2 in syndromic neurodevelopmental disorders
- A chemist’s adventures in immunology: Probing the T-cell activation pathway at the single cell and single molecule-level with n...
- Variations in 3D genome structure between homologous chromosomes and in stimulus responses
- Variations in 3D genome structure between homologous chromosomes and in stimulus responses
- Single-cell brain organoid screening identifies developmental defects in autism
- A Novel Type of IDH Wild-type Glioma Characterized by Gliomatosis Cerebri-like Growth Pattern, TERT Promoter Mutation, and Distinct Epigenetic Profile
- Small-molecule-induced epigenetic rejuvenation promotes SREBP condensation and overcomes barriers to CNS myelin regeneration
- INTERCEPT H3: a multicenter phase I peptide vaccine trial for the treatment of H3-mutated diffuse midline gliomas
- Logical design of synthetic cis-regulatory DNA for genetic tracing of cell identities and state changes
- Chromatin organization and behavior in living human cells revealed by single-nucleosome imaging
- Chromatin loop dynamics during cellular differentiation are associated with changes to both anchor and internal regulatory features
- Single-Cell Transcriptomics and In Vitro Lineage Tracing Reveals Differential Susceptibility of Human iPSC-Derived Midbrain Dopaminergic Neurons in a Cellular Model of Parkinson's Disease
- Morphine-withdrawal aversive memories and their extinction modulate H4K5 acetylation and Brd4 activation in the rat hippocampus and basolateral amygdala
- Epigenetics of Genes Preferentially Expressed in Dissimilar Cell Populations: Myoblasts and Cerebellum
- The Epigenetic Landscape of Meningiomas
- Organization of the human intestine at single-cell resolution
- The multifaceted functions of long non-coding RNA HOTAIR in neuropathologies and its potential as a prognostic marker and therapeutic biotarget
- The multifaceted functions of long non-coding RNA HOTAIR in neuropathologies and its potential as a prognostic marker and therapeutic biotarget
- Differential variability analysis of single-cell gene expression data
- Subpopulation commensalism promotes Rac1-dependent invasion of single cells via laminin-332
- Spatial proteomics reveals human microglial states shaped by anatomy and neuropathology
- Mapping pediatric brain tumors to their origins in the developing cerebellum
- Dysregulated glial genes in Alzheimer's disease are essential for homeostatic plasticity: Evidence from integrative epigenetic and single cell analyses
- Chromatin modifiers in human disease: from functional roles to regulatory mechanisms
- Dynamic chromatin accessibility during nutritional iron overload reveals a BMP6-independent induction of cell cycle genes
- Accelerated aging in bipolar disorders: An exploratory study of six epigenetic clocks
- Leveraging single-cell ATAC-seq and RNA-seq to identify disease-critical fetal and adult brain cell types
- Epigenetic regulation in major depression and other stress-related disorders: molecular mechanisms, clinical relevance and therapeutic potential
- How myeloid cells shape experimental autoimmune encephalomyelitis: at the crossroads of outside-in immunity
- A neuron-specific microexon ablates the novel DNA-binding function of a histone H3K4me0 reader PHF21A
- Pattern Recognition of Common Multiple Congenital Malformation Syndromes with Underlying Chromatinopathy
- Single-cell transcriptomics of NRAS-mutated melanoma transitioning to drug resistance reveals P2RX7 as an indicator of early drug response
- Single-nucleus profiling identifies accelerated oligodendrocyte precursor cell senescence in a mouse model of Down Syndrome
- Single-Nucleus RNA-Sequencing in Brain Tissue
- Integrated molecular analysis reveals hypermethylation and overexpression of HOX genes to be poor prognosticators in IDH mutant glioma
- B cell depletion attenuates CD27 signaling of T helper cells in multiple sclerosis
- Single-Cell RNA-Sequencing in Astrocyte Development, Heterogeneity, and Disease
- Lifelong restructuring of 3D genome architecture in cerebellar granule cells
- Genome wide association joint analysis reveals 99 risk loci for pain susceptibility and pleiotropic relationships with psychiatric, metabolic, and immunological traits
- Utility of combining OLIG2 and SOX10 IHC expression in CNS tumours: promising biomarkers for subtyping paediatric- and adult-type gliomas
- Deciphering early human pancreas development at the single-cell level
- Pleiotropy of autism-associated chromatin regulators
- Single-molecule and single-cell epigenetics: Decoding the epigenome for cancer research and diagnostics
- USP7/Maged1-mediated H2A monoubiquitination in the paraventricular thalamus: an epigenetic mechanism involved in cocaine use disorder
- High throughput functional profiling of genes at intraocular pressure loci reveals distinct networks for glaucoma
- COVID-19 antigen processing & T-cell response profiled by (single cell) proteomics
- The genomic alterations in glioblastoma influence the levels of CSF metabolites
- Partial Reprogramming as a Method for Regenerating Neural Tissues in Aged Organisms