Sleep Biomarkers for Predicting Cognitive Decline and Alzheimer’s Disease: A Systematic Review of Longitudinal Studies

3 December 2023

Evidence

J Alzheimers Dis. 2023 Nov 29. doi: 10.3233/JAD-230933. Online ahead of print.

ABSTRACT

BACKGROUND: Sleep disturbances are considered a hallmark of dementia, and strong evidence supports the association between alterations in sleep parameters and cognitive decline in patients with mild cognitive impairment and Alzheimer’s disease (AD).

OBJECTIVE: This systematic review aims to summarize the existing evidence on the longitudinal association between sleep parameters and cognitive decline, with the goal of identifying potential sleep biomarkers of AD-related neurodegeneration.

METHODS: Literature search was conducted in PubMed, Web of Science, and Scopus databases from inception to 28 March 2023. Longitudinal studies investigating the association between baseline objectively-measured sleep parameters and cognitive decline were assessed for eligibility.

RESULTS: Seventeen studies were included in the qualitative synthesis. Sleep fragmentation, reduced sleep efficiency, reduced REM sleep, increased light sleep, and sleep-disordered breathing were identified as predictors of cognitive decline. Sleep duration exhibited a U-shaped relation with subsequent neurodegeneration. Additionally, several sleep microstructural parameters were associated with cognitive decline, although inconsistencies were observed across studies.

CONCLUSIONS: These findings suggest that sleep alterations hold promise as early biomarker of cognitive decline, but the current evidence is limited due to substantial methodological heterogeneity among studies. Further research is necessary to identify the most reliable sleep parameters for predicting cognitive impairment and AD, and to investigate interventions targeting sleep that can assist clinicians in the early recognition and treatment of cognitive decline. Standardized procedures for longitudinal studies evaluating sleep and cognition should be developed and the use of continuous sleep monitoring techniques, such as actigraphy or EEG headband, might be encouraged.

PMID:38043016 | DOI:10.3233/JAD-230933

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Loneliness, social isolation and incident chronic kidney disease among patients with diabetes 4 June 2024
Background Individuals with diabetes have a significantly higher risk of developing chronic kidney disease (CKD) and higher levels of social isolation and loneliness compared with those without diabetes. Recently, the American Heart Association highlighted the importance of considering social determinants of health (SDOH) in conjunction with traditional risk factors in patients with diabetes. Aims To […]
Tang, R., Zhou, J., Wang, X., Ma, H., Li, X., Heianza, Y., Qi, L.

Correction: Curcumin and proton pump inhibitors for functional dyspepsia: a randomised, double blind controlled trial 14 June 2024
Kongkam P, Khongkha W, Lopimpisuth C, et al Curcumin and proton pump inhibitors for functional dyspepsia: a randomised, double blind controlled trial BMJ Evidence-Based Medicine 2023;28:399-406.The journal received a rapid response that raised issues regarding the registration status of this trial and the methods. The journal investigated these issues with the collaboration of the authors, […]
iHealthFacts: a health fact-checking website for the public 14 June 2024
Introduction and backgroundUnreliable health information has been identified as a public health challenge. It may lead individuals to explore unproven and potentially harmful medical treatments1 or cause delays in seeking appropriate healthcare services.2Determining the accuracy of health information is especially challenging in the digital age.3 These challenges were underscored by the onset of the COVID-19 […]
Byrne, P., Daly, A., Mac Loughlin, D., Madden, C., Mc Donnell, T., O'Connell, C., Pope, J., Saif-Ur-Rahman, K. M., Taneri, P. E., Tierney, M., Toomey, E., Devane, D.
Meet generative AI... your new shared decision-making assistant 12 June 2024
IntroductionLarge language models (LLMs), a new family of tools to generate natural language, are likely to radically change how some aspects of healthcare are delivered.1 It is difficult to comprehend the pace at which change is already occurring. For example, ChatGPT, released by OpenAI in November 2022, represented a leap in the capability of artificial […]
Elwyn, G., Ryan, P., Blumkin, D., Weeks, W. B.

Change in attitudes after a suicide prevention media campaign in the Mid-Norway region 14 June 2024
Suicide prevention media campaigns are one way of reaching people at increased suicide risk who would otherwise not seek help. This is the first study of a Norwegian campaign directed both at individuals at ri...
Christine Mohn, Egil Haga, Hanne Sofie Wernoe Nilsson, Jane Pirkis and Lars Mehlum
Effects of brief family psychoeducation on family caregiver burden of people with schizophrenia provided by psychiatric visiting nurses: a cluster randomised controlled trial 14 June 2024
The purpose of this study was to examine the effects of a brief family psychoeducation (BFP) programme provided by psychiatric visiting nurses on caregiver burden of family caregivers of people with schizophre...
Naonori Yasuma, Sayaka Sato, Sosei Yamaguchi, Asami Matsunaga, Takuma Shiozawa, Hisateru Tachimori, Kazuhiro Watanabe, Kotaro Imamura, Daisuke Nishi, Chiyo Fujii and Norito Kawakami
Evaluation of dialectical behavior therapy for adolescents in routine clinical practice: a pre-post study 14 June 2024
Self-harm and suicidal ideation are prevalent among adolescents, cause physical and psychosocial disability, and have potentially life-threatening consequences. Dialectical behavioral therapy for Adolescents (...
Anne Mari Syversen, Viktor Schønning, Gro Sydnes Fjellheim, Irene Elgen and Gro Janne Wergeland

King Charles III retains patronage of Royal College of Psychiatrists
The Royal College of Psychiatrists is thrilled to announce His Majesty The King has retained his patronage of the College.
www.rcpsych.ac.uk
Maternal Mental Health Awareness Week
This Maternal Mental Health Awareness Week, we’re highlighting our mental health leaflets for patients and their families.
www.rcpsych.ac.uk
‘Discrimination against people with severe mental illness is cutting lives short’
The President of the Royal College of Psychiatrists, Dr Lade Smith CBE, warns that prejudice against people with severe mental illness prevents them from seeking help and cuts lives short.
www.rcpsych.ac.uk

Capacity to Consent to Treatment of Substance Use Disorders at Ontario's Consent and Capacity Board: A Review of Past Reported Decisions 14 June 2024
The Canadian Journal of Psychiatry, Ahead of Print. Capacity to consent to treatment of substance use disorders at Ontario's Consent and Capacity Board: A review of past reported decisionsPlain Language Summary TitleAn Ontario review of legal cases which have considered patients' ability to consent to substance use treatmentsPlain Language SummaryIn general, prescribers must consider whether […]
Tanya S. Hauck
Effect of Bright Light Therapy on Perinatal Depression: A Systematic Review and Meta-Analysis: Effet de la luminothérapie sur la dépression périnatale: une revue systématique et une méta-analyse 12 June 2024
The Canadian Journal of Psychiatry, Ahead of Print. ObjectiveThis study represents the inaugural attempt to systematically review and analyse the efficacy of bright light therapy on depression among women experiencing major depressive disorder or depressive symptoms during the perinatal period, encompassing its efficacy on depression scores, remission rates, and response rates.MethodsWe searched 10 databases for […]
Yujia Chen
Commentary on the Canadian Network for Mood and Anxiety Treatments 2023 Clinical Guidelines for Management of Major Depressive Disorder in Adults – Capturing the State of the Art 10 June 2024
The Canadian Journal of Psychiatry, Ahead of Print.
Katherine Beck

Responding to rising measles rates in Canada 3 June 2024
Send us a Text Message.On this episode of the CMAJ Podcast, Dr. Blair Bigham and Dr. Mojola Omole tackle an unexpected yet urgent topic: the resurgence of measles. With rising cases globally and in Canada, they discuss the implications and necessary actions for healthcare professionals.Dr. Sarah Wilson, a public health physician at Public Health Ontario, […]
Canadian Medical Association Journal
Constructive conversations on CanMEDS revisions 20 May 2024
Send us a Text Message.On this episode of the CMAJ Podcast, Dr. Blair Bigham and Dr. Mojola Omole discuss the heated debate over proposed updates to the CanMEDS framework. The controversy ignited when an interim report placed principles of equity, social justice, and anti-racism at the heart of the framework, rather than medical expertise.Dr. Kannin […]
Canadian Medical Association Journal
Navigating the complex relationship between palliative care and MAiD 6 May 2024
Send us a Text Message.On this episode of the CMAJ Podcast, Dr. Blair Bigham and Dr. Mojola Omole explore the intricate relationship between medical assistance in dying (MAiD) and palliative care in Canada. They focus on a qualitative study titled "Perspectives of Canadian healthcare leaders on the relationship between medical assistance in dying and palliative […]
Canadian Medical Association Journal

Bloom’s taxonomy—Can evidence-based teaching improve junior medical officers’ knowledge of the mental health and guardianship acts? 15 June 2024
Australasian Psychiatry, Ahead of Print. ObjectiveTo determine whether a brief educational intervention for Junior Medical Officers (JMOs), using teaching methods aimed at achieving higher outcomes on Bloom’s Taxonomy, significantly improved participant confidence and knowledge in decision making about restrictive care.MethodJMOs received a teaching session on restrictive medical and mental health care. Groups were randomly assigned […]
Trent Koessler
Any psychiatric assessment of a drowsy patient must be preliminary 15 June 2024
Australasian Psychiatry, Ahead of Print.
Mathew Coleman
Disillusionment amongst clinical staff experiencing repeated change 14 June 2024
Australasian Psychiatry, Ahead of Print. ObjectiveTo describe disillusionment amongst the clinical community as a result of repeated ideological and organisational change and to suggest a road map forward.ConclusionDespite knowing that change can be disruptive, it will likely remain a constant and necessary feature of organisational life. Various approaches, including the development of a personal sphere […]
John Little

The effects of inpatient suicide on nurses at Weskoppies Hospital: A qualitative study 21 May 2024
Background: Inpatient suicide is a serious adverse event in psychiatric wards. Suicide can cause severe trauma to both patients and health professionals, who may develop maladaptation with poor coping skills. Healthcare practitioners are the second victims and historically, this concept has been overlooked. The psychological effects and lack of support have not been sufficiently explored.Aim: The emotional […]
Nomthandazo Zola
Clinical profile of children and adolescents with autism spectrum disorder in Durban, South Africa 14 May 2024
Background: There are often delays in accessing care and diagnosing autism spectrum disorders (ASDs), with little data from Southern Africa on the clinical profile of affected children and adolescents.Aim: To describe the socio-demographic and clinical variables of children and adolescents with ASD attending psychiatric services at two state hospitals in eThekwini Municipality, KwaZulu-Natal province, South Africa.Setting: Two state […]
Manisharani Gangai
Views held by South African primary health care nurses on caring for people living with mental illness 3 May 2024
Background: Primary healthcare is the first point of entry into the healthcare system. Scaling up primary mental healthcare is recommended in South African mental health policy. However, there is a paucity of data exploring the views of primary healthcare nurses (PHCNs) with regards to caring for people living with mental illness (PLWMI) in South Africa.Aim: To explore […]
Nokukhanya Phungula

Standards for randomized controlled trials of efficacy of psychological treatments 10 May 2024
World Psychiatry, Volume 23, Issue 2, Page 286-287, June 2024.
David C. Mohr
The future of dynamic networks in research and clinical practice 10 May 2024
World Psychiatry, Volume 23, Issue 2, Page 288-289, June 2024.
Laura F. Bringmann
Algorithm‐based modular psychotherapy vs. cognitive‐behavioral therapy for patients with depression, psychiatric comorbidities and early trauma: a proof‐of‐concept randomized controlled trial 10 May 2024
World Psychiatry, Volume 23, Issue 2, Page 257-266, June 2024.
Elisabeth Schramm, Moritz Elsaesser, Carolin Jenkner, Martin Hautzinger, Sabine C. Herpertz

The single-cell opioid responses in the context of HIV (SCORCH) consortium 15 June 2024
Molecular Psychiatry, Published online: 15 June 2024; doi:10.1038/s41380-024-02620-7The single-cell opioid responses in the context of HIV (SCORCH) consortium
Seth A. Ament
Transmissible long-term neuroprotective and pro-cognitive effects of 1–42 beta-amyloid with A2T icelandic mutation in an Alzheimer’s disease mouse model 14 June 2024
Molecular Psychiatry, Published online: 14 June 2024; doi:10.1038/s41380-024-02611-8Transmissible long-term neuroprotective and pro-cognitive effects of 1–42 beta-amyloid with A2T icelandic mutation in an Alzheimer’s disease mouse model
Marina Célestine
Neural mechanisms of psychedelic visual imagery 11 June 2024
Molecular Psychiatry, Published online: 11 June 2024; doi:10.1038/s41380-024-02632-3Neural mechanisms of psychedelic visual imagery
Devon Stoliker

Seq-ing mechanisms behind types of Alzheimer’s disease
Sporadic Alzheimer’s disease (AD) and autosomal dominant Alzheimer’s disease (ADAD) share pathological features, but differing mechanisms, leading to disease. In this issue of , Almeida, Eger, et al. uncovered molecular processes that may distinguish sporadic AD from ADAD and how the APOE-Christchurch variant may be protective.Sporadic Alzheimer’s disease (AD) and autosomal dominant Alzheimer’s disease (ADAD) share […]
From bile acids to melancholia
In this issue of , Li, Zhang, et al. find that the bile acid receptor TGR5 in the lateral hypothalamus influences neuronal dynamics underlying stress-induced depression-like behaviors. Inhibition of these neurons produces antidepressant-like effects through a circuit that includes hippocampal CA3 and dorsolateral septum, revealing a novel potential therapeutic for depression.In this issue of , Li, […]
Turning down the body heat: A novel mechanism for TRPV1 antagonist-induced hyperthermia
While effective analgesics, TRPV1 antagonists can dangerously alter thermoregulation. In this issue of , Huang et al. demonstrate that interaction with the S4-S5 linker of TRPV1 determines whether an antagonist affects core body temperature, with promising implications for analgesic development.While effective analgesics, TRPV1 antagonists can dangerously alter thermoregulation. In this issue of , Huang et al. demonstrate […]

Prescription psychostimulant use, admissions and treatment initiation and retention in pregnant people with opioid use disorder 11 June 2024
Nature Mental Health, Published online: 11 June 2024; doi:10.1038/s44220-024-00270-wIn this Article, the authors present data showing that pregnant people seeking treatment for opioid use disorder who receive psychostimulant medication for attention deficit hyperactivity disorder were more likely to initiate and adhere to treatment with buprenorphine.
Kevin Y. Xu
Reflecting on LGBT+ mental health 11 June 2024
Nature Mental Health, Published online: 11 June 2024; doi:10.1038/s44220-024-00274-6June marks the month-long observance of Pride, when individuals, institutions and organizations come together to celebrate through jubilant displays of the rainbow flag, by sharing personal experiences and memories, and by demonstrating support for lesbian, gay, bisexual, transgender, questioning/queer, intersex, asexual (LGBT+) communities and allies.
An integrated understanding of the mechanisms linking social stigma to mental health among marginalized populations 10 June 2024
Nature Mental Health, Published online: 10 June 2024; doi:10.1038/s44220-024-00264-8In this Perspective, the authors present an integrative model aimed at understanding and explaining the mechanisms that account for the impact of stigma on the mental health of multiple marginalized populations.
David M. Frost

Linking haploinsufficiency of the autism- and schizophrenia-associated gene Cyfip1 with striatal-limbic-cortical network dysfunction and cognitive inflexibility 14 June 2024
Translational Psychiatry, Published online: 14 June 2024; doi:10.1038/s41398-024-02969-xLinking haploinsufficiency of the autism- and schizophrenia-associated gene Cyfip1 with striatal-limbic-cortical network dysfunction and cognitive inflexibility
Josephine E. Haddon
Shared and unique alterations of large-scale network connectivity in drug-free adolescent-onset and adult-onset major depressive disorder 12 June 2024
Translational Psychiatry, Published online: 12 June 2024; doi:10.1038/s41398-024-02974-0Shared and unique alterations of large-scale network connectivity in drug-free adolescent-onset and adult-onset major depressive disorder
Ximan Hou
Decoding the inflammatory signature of the major depressive episode: insights from peripheral immunophenotyping in active and remitted condition, a case–control study 12 June 2024
Translational Psychiatry, Published online: 12 June 2024; doi:10.1038/s41398-024-02902-2Decoding the inflammatory signature of the major depressive episode: insights from peripheral immunophenotyping in active and remitted condition, a case–control study
Federico Manuel Daray

WFP News Section 21 May 2024
Oxytocin-Augmented Modular-Based Group Intervention for Loneliness: A Proof-Of-Concept Randomized Controlled Trial 16 May 2024
AbstractIntroduction: Loneliness poses a significant health problem and existing psychological interventions have shown only limited positive effects on loneliness. Based on preliminary evidence for impaired oxytocin signaling in trait-like loneliness, the current proof-of-concept study used a randomized, double-blind, placebo-controlled design to probe intranasal oxytocin (OT) as an adjunct to a short-term modular-based group intervention for […]
Efficacy of an Internet- and Mobile-Based Intervention for Subclinical Anxiety and Depression (ICare Prevent) with Two Guidance Formats: Results from a Three-Armed Randomized Controlled Trial 30 April 2024
AbstractIntroduction: Limited research exists on intervention efficacy for comorbid subclinical anxiety and depressive disorders, despite their common co-occurrence. Internet- and mobile-based interventions (IMIs) are promising to reach individuals facing subclinical symptoms. Objective: This study aimed to evaluate the efficacy of a transdiagnostic and self-tailored IMI in reducing subclinical anxiety and depressive symptom severity with either […]

First-trimester use of antiseizure medications and the risk of miscarriage: a population-based cohort study 14 June 2024
BackgroundAntiseizure medications (ASMs) during the first trimester of pregnancy have been associated with an increased risk of miscarriage.MethodsWe carried out a population-based cohort study using routinely collected healthcare data from the UK, 1995–2018. Pregnancies were identified in the Clinical Practice Research Datalink and we estimated the HR of miscarriage associated with prescriptions of ASMs during […]
Forbes, H., Madley-Dowd, P., Ahlqvist, V., Campbell, J., Davies, N. M., Liebling, R., Lyall, K., Newschaffer, C., Rast, J., Tomson, T., Zhong, C., Magnusson, C., Rai, D., Lee, B. K.
Predicting how many people might receive treatment with new therapies for Alzheimers disease 11 June 2024
One hundred and seventeen years after Alzheimer described the condition that bears his name, the first treatments have been identified which appear to modify its course.1 2 These treatments are monoclonal antibodies which clear one of the presumed pathogenic proteins (amyloid) from the brain. This is welcome progress, but it has come with concerns including […]
Underwood, B. R.
Eligibility for antiamyloid treatment: preparing for disease-modifying therapies for Alzheimers disease 11 June 2024
BackgroundDisease-modifying therapies (DMTs) for Alzheimer’s disease (AD) have early evidence of efficacy. Widespread delivery of DMTs will require major service reconfiguration. Treatment pathways will need to include triaging for eligibility, regular infusions and baseline and follow-up MRI scanning. A critical step in planning is provision of real-world estimates of patients likely to be eligible for […]
Dobson, R., Patterson, K., Malik, R., Mandal, U., Asif, H., Humphreys, R., Payne, M., O-Charoenrat, E., Huzzey, L., Clare, A., Green, K., Morton, M., Sohrabi, C., Singh, N., Pasupathy, A., Patel, M., Whiteman, S., Maxmin, K., Bass, N., Gupta, B., Cooper, C., Marshall, C., Weil, R. S., Mummery, C. J.

Mendelian randomization: causal inference leveraging genetic data 19 April 2024
Mendelian randomization (MR) leverages genetic information to examine the causal relationship between phenotypes allowing for the presence of unmeasured confounders. MR has been widely applied to unresolved questions in epidemiology, making use of summary statistics from genome-wide association studies on an increasing number of human traits. However, an understanding of essential concepts is necessary for […]
Chen, Lane G.
Interventions targeting social determinants of mental disorders and the Sustainable Development Goals: a systematic review of reviews 25 March 2024
Globally, mental disorders account for almost 20% of disease burden and there is growing evidence that mental disorders are socially determined. Tackling the United Nations Sustainable Development Goals (UN SDGs), which address social determinants of mental disorders, may be an effective way to reduce the global burden of mental disorders. We conducted a systematic review […]
Oswald, Tassia Kate
Do metacognitive therapies for schizophrenia-spectrum disorders work? A meta-analytic investigation 21 March 2024
Recent reviews and meta-analyses of metacognitive therapy for schizophrenia-spectrum disorder (SSD) have included uncontrolled studies, single-session interventions, and/or analyses limited to a single form of metacognitive therapy. We sought to evaluate the efficacy of metacognitive therapies more broadly based on controlled trials (CT) of sustained treatments. We conducted a pre-registered meta-analysis of controlled trials that […]
Melville, Grace

Exploring the role of clinical and demographic characteristics on the effects of virtual reality cognitive behavioral therapy for psychosis: A moderator analysis 10 June 2024
Acta Psychiatrica Scandinavica, EarlyView.
M. Berkhof, E. C. D. van der Stouwe, R. M. C. A. Pot‐Kolder, M. van der Gaag, W. Veling, C. N. W. Geraets
Association between electroconvulsive therapy and time to readmission after a manic episode 5 June 2024
Acta Psychiatrica Scandinavica, Volume 150, Issue 1, Page 22-34, July 2024.
Katarzyna Popiolek, Tor Arnison, Susanne Bejerot, Katja Fall, Mikael Landén, Axel Nordenskjöld
Liraglutide 3.0 mg once daily for the treatment of overweight and obesity in patients hospitalised at a forensic psychiatric department: A 26‐week open‐label feasibility study 5 June 2024
Acta Psychiatrica Scandinavica, Volume 150, Issue 1, Page 35-47, July 2024.
Marie Reeberg Sass, Anne Mette Brandt Christensen, Margit Lykke Christensen, Ema Gruber, Helle Nerdrum, Lone Marianne Pedersen, Maximilian Resch, Troels Højsgaard Jørgensen, Claus T. Ekstrøm, Jimmi Nielsen, Tina Vilsbøll, Anders Fink‐Jensen

Efficacy and safety of remimazolam versus propofol for intraoperative sedation during regional anesthesia: A phase II, multicenter, randomized, active‐controlled, single‐blind clinical trial 16 June 2024
Ibrain, EarlyView.
Ting‐Ting Li, Lu Yin, Yue‐Xin Huang, Xiu‐Hong Wang, Yan‐Huan Wei, Yong Wang, Shi‐Wei Yang, Genoveva B. da Graca Cunha, Fei Liu
The Lived Experience of Informal Caregivers of People Who Have Severe Mental Illness and Coexisting Long‐Term Conditions: A Qualitative Study 16 June 2024
Health Expectations, Volume 27, Issue 3, June 2024.
C. Carswell, J. V. E. Brown, D. Shiers, R. Ajjan, A. Balogun‐Katung, S. Bellass, R. I. G. Holt, R. Jacobs, I. Kellar, C. Lewisohn, J. Lister, N. Siddiqi, I. Sidorova, P. Coventry
SEP‐363856 exerts neuroprotection through the PI3K/AKT/GSK‐3β signaling pathway in a dual‐hit neurodevelopmental model of schizophrenia‐like mice 16 June 2024
Drug Development Research, Volume 85, Issue 4, June 2024.
Mengdie Li, Yunxiao Liu, Meng Sun, Yating Yang, Ling Zhang, Yuexia Liu, Fujin Li, Huanzhong Liu

A role for Shugoshin in human cilia?
We have recently described a novel role for the conserved centromeric/kinetochore protein and cohesin protector, Shugoshin, in cilia of C. elegans. Worms are unusual in that the sole Shugoshin protein ( SGO-1 ) is dispensable for chromosome segregation but required for cilia function in fully differentiated sensory neurons. Depletion of sgo-1 leads to an array […]
sut-2 loss of function mutants protect against tau-driven shortened lifespan and hyperactive pharyngeal pumping in a C. elegans model of tau toxicity.
Expression of human tau in C. elegans neurons causes progressive, age-associated loss of motor coordination, selective neurodegeneration, and shortened lifespan. Loss of function (LOF) mutations in the conserved gene sut-2 protects against progressive motor uncoordination and neurodegeneration in models of tauopathy. To determine whether sut-2 LOF also protects against shortened lifespan of tau transgenic C. […]
Evidence Based Clinical Analytics Supporting the Genetic Addiction Risk Severity (GARS) Assessment to Early Identify Probands in Preaddiction.
No abstract supplied.

Addressing the Youth Mental Health Epidemic
A Model for Providing Psychological Support to Healthcare Leaders and Teams in Times of Crisis
Pre-pandemic, the healthcare workforce was already at risk for higher burnout than the general population and, in some roles (e.g., physicians, nurses), at higher risk for clinical distress and suicide. Studies of healthcare workforce well-being during and after past pandemics reflect that distress can persist after a pandemic subsides, if adequate support within the workplace […]
Assessment of Brief Online Approaches for Teaching Neuroscience in Psychiatry
The goal of this study was to assess an online collection of brief educational resources (videos, case studies, articles) for teaching a broad range of concepts relating to neuroscience in psychiatry.A national sample of 52 psychiatrists enrolled in the study. Forty (77%) completed an assessment before and after having access to the educational resources for […]

Vitamin B12 Supplementation in Psychiatric Practice
Vitamin B (B12, cobalamin) deficiency has been associated with neuropsychiatric symptoms, suggesting a role for B12 supplementation both as a treatment for psychiatric symptoms due to B12 deficiency and as an augmentation strategy for pharmacological treatments of psychiatric disorders. This critical review discusses the major causes of B12 deficiency, the range of psychiatric and non-psychiatric […]
Dignity in Medicine: Definition, Assessment and Therapy
Over the last 20 years, dignity and dignity-conserving care have become the center of investigation, in many areas of medicine, including palliative care, oncology, neurology, geriatrics, and psychiatry. We summarized peer-reviewed literature and examined the definition, conceptualization of dignity, potential problems, and suggested interventions.We performed a review utilizing several databases, including the most relevant studies […]
Metaverse in Mental Health: The Beginning of a Long History
We review the first pilot studies applying metaverse-related technologies in psychiatric patients and discuss the rationale for using this complex federation of technologies to treat mental diseases. Concerning previous virtual-reality applications in medical care, metaverse technologies provide the unique opportunity to define, control, and shape virtual scenarios shared by multi-users to exploit the “synchronized brains” […]

Editorial Board
The efficacy of psychotherapy for social anxiety disorder, a systematic review and meta-analysis
Largest meta-analysis about psychotherapy for SAD (66 studies with 98 comparisons).Psychotherapy is an effective treatment for SAD ( = 0.88, NNT = 3.8).Moderate to large effect sizes across all treatment types and formats.Self-help treatments can increase psychotherapy scalability in low-resource settings. Given the growth in research examining the effects of psychotherapy on social anxiety disorder […]
Metacognitive therapy versus exposure and response prevention for obsessive-compulsive disorder – A non-inferiority randomized controlled trial
Metacognitive therapy is an effective treatment for obsessive-compulsive disorder.Metacognitive therapy is comparably successful as exposure with response prevention.Therapies for OCD should be optimized to reduce rate of patients with residual symptoms. Exposure with response prevention (ERP) is the first-line treatment for obsessive-compulsive disorder (OCD). However, refusals, dropouts and the required high time and logistic effort […]

Socio‐demographic variation in diagnosis of and prescribing for common mental illnesses among children and young people during the COVID‐19 pandemic: time series analysis of primary care electronic health records 15 June 2024
Journal of Child Psychology and Psychiatry, EarlyView.
Louise Jane Hussey, Evan Kontopantelis, Pearl L. H. Mok, Darren M. Ashcroft, Matthew J. Carr, Shruti Garg, Carolyn A. Chew‐Graham, Nav Kapur, Karina Lovell, Roger T. Webb
Sex differences in attention‐deficit hyperactivity disorder diagnosis and clinical care: a national study of population healthcare records in Wales 12 June 2024
Journal of Child Psychology and Psychiatry, EarlyView.
Joanna Martin, Kate Langley, Miriam Cooper, Olivier Y. Rouquette, Ann John, Kapil Sayal, Tamsin Ford, Anita Thapar
Research Review: Social cognition and everyday social skills in children and adolescents with attention‐deficit/hyperactivity disorder: a meta‐analysis of case–control studies 11 June 2024
Journal of Child Psychology and Psychiatry, EarlyView.
Belen Haza, Corentin J. Gosling, Flavia Ciminaghi, Laurence Conty, Charlotte Pinabiaux

Insomnia and fibromyalgia-like symptoms among women diagnosed with relapsing remitting multiple sclerosis in Jordan: Prevalence and correlates 21 May 2024
The International Journal of Psychiatry in Medicine, Ahead of Print. ObjectiveThis study investigated the prevalence and correlates of fibromyalgia and insomnia in a sample of Women with Multiple Sclerosis (WMS).MethodsThe study was cross-sectional in design and recruited a sample of 163 women with Relapsing-Remitting Multiple Sclerosis (RRMS). Fibromyalgia was assessed using the Patient Self-Report Survey […]
Omar Gammoh
Prevalence and risk factors for chronic kidney disease among older adult patients with schizophrenia in Taiwan 20 May 2024
The International Journal of Psychiatry in Medicine, Ahead of Print. ObjectivesThere is an increasing incidence and prevalence of patients with chronic kidney disease (CKD) worldwide. Little is known the prevalence of CKD among older patients with schizophrenia. The purpose of this study was to investigate the prevalence of CKD and its risk factors in older […]
Shu-Ting Chang
All medical workers together: For better mental health and primary health care- Posters 29 April 2024
The International Journal of Psychiatry in Medicine, Volume 59, Issue 3_suppl, Page 1S-103S, May 2024.

Treating depression in patients with borderline personality disorder: clinical clues on the use of antidepressants 30 May 2024
Personality disorders (PD) are described as enduring patterns of markedly deviant and pervasive inner experiences and behaviors, with onset in adolescence, which lead to severe distress or impairment. Patients...
Carmine Tomasetti, G. Autullo, A. Ballerini, A. de Bartolomeis, B. Dell’Osso, A. Fiorentini, F. Tonioni, V. Villari and D. De Berardis
Individualized strategies for depression: narrative review of clinical profiles responsive to vortioxetine 16 May 2024
Depression is a highly heterogeneous disorder, often resulting in suboptimal response and remission rates. This underscores the need for more nuanced clinical characterization of patients to tailor individuali...
Alessandro Cuomo, Andrea Aguglia, Domenico De Berardis, Antonio Ventriglio, Camilla Gesi and Andrea Fagiolini
Measurement of perceived pressures in psychiatry: paper-and-pencil and computerized adaptive version of the P-PSY35 scale 10 May 2024
Formal coercion in psychiatry is widely studied yet much less is known about pressures patients may experience, partly because of the very few measures available. The goal of this study was to validate the P-P...
Philippe Golay, Debora Martinez, Mizué Bachelard, Benedetta Silva, Alexandra Brodard, Jonathan Perrin, Nolan Pedro Fernando, Lou-Ann Renaud, Charles Bonsack and Stéphane Morandi

Blighted phenomena: Learning to work with the dark. 8 April 2024
Blighted phenomena are understood as derivatives of dark, lonely, injured experiences—those that are often difficult to put into words. These phenomena can manifest in innumerable configurations in patients’ presentations and in the specificity of their developmental struggles and language. The present article aims to describe ways of working with the darkness of blighted experience, through […]
Intimate partner violence: Narratives of attachment relationships and linguistic analysis of emotional schemas through a quali-quantitative approach. 18 January 2024
Intimate partner violence (IPV) is a concerning, widespread issue with serious health, social, and financial consequences. Previous studies highlighted the role of insecure attachment patterns in predicting IPV victimization. This study investigates attachment classifications among women survivors of IPV referred to antiviolence centers, as determined by the Adult Attachment Interview and compare them with a […]
Review of Reading French Psychoanalysis. 25 December 2023
Reviews the book, Reading French Psychoanalysis edited by Dana Birksted-Breen, Sara Flanders, and Alain Gibeault (2010). In this essay, the author discusses eight reviews of Reading French Psychoanalysis. The reviews considered are Cheshire (2010) in the British Journal of Psychotherapy, Forde (2010) in the Revista de Psicoanálisis, Glassgold (2014) in the Psychoanalytic Quarterly, Lefer (2011) […]

Development and validation of the Gender Identity and Expression Microaggressions in Therapy Scale (GIEMTS). 18 April 2024
Developing affirming interventions for transgender and nonbinary (TNB) therapy clients requires understanding their experiences with microaggressions in psychotherapy, yet no self-report measure of anti-TNB microaggressions in this context exists. Moreover, few studies have tested the associations between anti-TNB microaggressions and therapy processes. To better address the burden of unmet mental health care needs among TNB […]
The evolution of feedback: Toward a multicultural orientation. 18 April 2024
There have been great strides in psychology regarding diversity, equity, inclusion, and multicultural competence, but a need remains to translate these values into actionable practices in psychotherapy. While the case has been made that measurement-based care is an evidence-based intervention that improves outcomes and reduces dropouts (de Jong et al., 2021) and recently that it […]
Beyond the dyad: Broadening the APA supervision guidelines to include group supervision. 28 March 2024
Group supervision is an extensively used format across many training agencies, yet it has been largely disregarded in theory and research within the supervision literature. In fact, the Guidelines for Clinical Supervision in Health Service Psychology (American Psychological Association, 2015a) mentions group supervision only one time, despite the fact that supervision within a group context […]

A Community Data Sharing Resource: The LDbase Data Repository 29 May 2024
Journal of Learning Disabilities, Ahead of Print. The purpose of this invited paper is to show the learning disabilities field what LDbase is, why it’s important for the field, what it offers the field, and examples of how you can leverage LDbase in your own work.
Sara A. Hart
Teaching Constant Rate-of-Change Problem-Solving to Secondary Students With or at Risk of Learning Disabilities 21 May 2024
Journal of Learning Disabilities, Ahead of Print. Rate of change (i.e., slope) is a critical mathematics concept for success in everyday life, academics, and professional careers. Students with or at risk of learning disabilities struggle with solving rate-of-change problems, especially word problems. Interventions that incorporate representations and problem-solving strategies are effective for improving the word […]
Kaitlin Bundock
Concept-Focused and Procedure-Focused Instruction on the Algebra Performance of Grade 9 Students With and Without Mathematics Difficulty 18 May 2024
Journal of Learning Disabilities, Ahead of Print. Developing both conceptual and procedural knowledge is important for students’ mathematics competence. This study examined whether Grade 9 general education mathematics teachers’ self-reported use of concept-focused instruction (CFI) and procedure-focused instruction (PFI) were associated differently with ninth graders’ algebra achievement after 2.5 years, depending on students’ mathematics difficulty […]
Jihyun Lee

Consumer decisions in virtual commerce: Predict good help-timing based on cognitive load. 10 June 2024
The retail sector is steadily moving toward virtual commerce (v-commerce), and the process has recently gained momentum. With the latest developments in headset technology and the rise of artificial intelligence, virtual shopping has become relevant for an increasing number of products. In this article, we present a study that combines consumer behavior research, eye tracking, […]
Correction to “Magnitude effects in preference reversals” by Lu and Nieznański (2021). 10 June 2024
Reports an error in "Magnitude effects in preference reversals" by Yong Lu and Marek Nieznański (Journal of Neuroscience, Psychology, and Economics, 2021[Sep], Vol 14[3], 149-184). In the article, the authors analyzed the data by applying an inappropriate statistical methodology, the Kruskal–Wallis analysis of variance by ranks, for mixed-subjects comparisons (i.e., one sample group of 57 […]
Fast and wrong: An eye-tracking exploration on how low “cognitive reflection” people analyze and choose commercial packages with multidimensional prices. 10 June 2024
Based on the literature on individual differences in cognitive processes, we analyzed gaze behavior during a purchase decision context to understand if the levels of cognitive reflection affect the type of price-information processing and, in turn, the quality of choice. The participants were presented with two websites selling the same commercial package and asked to […]

EJIHPE, Vol. 14, Pages 1735-1756: The Relationship among Internet Addiction, Moral Potency, Mindfulness, and Psychological Capital 16 June 2024
This research aimed to contribute to the literature on internet addiction (IA) and moral development among university students. Moral potency (MP) encompasses the interconnected dimensions of moral courage, moral ownership, and moral efficacy. Studies on the relationships between students’ problematic behaviors (e.g., IA) and cognitive processes like MP, mindfulness (MI), and psychological capital (PsyCap) are […]
Girum Tareke Zewude
EJIHPE, Vol. 14, Pages 1722-1734: Dyadic Prenatal Coparenting Interaction Behaviors Predicting Postpartum Depressive Symptoms during the Transition to Parenthood 13 June 2024
Postpartum depressive symptoms constitute a common yet serious complication of pregnancy and childbirth, but research on its association with coparenting is scarce. Furthermore, although coparenting dynamics start forming prior to the child’s birth, no research has explored dyadic prenatal coparenting dynamics as a predictor of postpartum depressive symptoms. The current study assessed how dyadic prenatal […]
Roi Estlein
EJIHPE, Vol. 14, Pages 1700-1711: Construction and Validation of an Educational Technology to Promote the Health of Postmenopausal Women with Dry Eye Syndrome 12 June 2024
The climacteric heralds a transition from reproductive to non-reproductive life in women, often accompanied by various clinical manifestations such as dry eye, impacting their quality of life. This study focuses on systematically developing and suitability an educational digital booklet to promote eye health practices and prevent problems among postmenopausal women. The methodological approach encompassed semi-structured […]
Álvaro de Almeida Junior

Relationships between adverse childhood experiences, attachment, resilience, psychological distress and trauma among forensic mental health populations 12 June 2024
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Katie Finch Daniel Lawrence Marc O. Williams Andrew R. Thompson Christopher Hartwright a School of Psychology, Cardiff University, UKb Priory Group, Priory Healthcare, Monmouthshire, UKc Department of Applied Psychology, Cardiff Metropolitan University, UK
Unlocking a taboo topic: the sexuality of institutionalized men within a forensic psychiatric facility 29 May 2024
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Frédérique Fortin Jo-Annie Spearson Goulet Mathieu Goyette Ashley J. Lemieux a Department of Sexology, Université du Québec à Montréal, Canadab Research Center, Institut national de psychiatrie légale Philippe-Pinel, Montreal, Canadac Department of Psychiatry and Addiction, Université de Montréal, Canada
Evaluation of the Enhanced Engagement and Relational Support Service (EERSS) within the Offender Personality Disorder (OPD) pathway 26 May 2024
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Bardana Singh Roxanna Short Philip Minoudis a London Pathways Partnership, UKb Forensic Personality Disorder Psychology Department, East London NHS Foundation Trust, UKc Forensic and Neurodevelopmental Sciences, Kings College London, UK

The CRPD and mental health law reform in Scotland
Scotland's mental health and capacity legislation and its implementation is underpinned by European Convention on Human Rights (ECHR) informed principles, and such legislation and its implementation has remained largely ECHR compliant. It is designed to protect individuals' autonomy from inappropriate and disproportionate nonconsensual intrusions but its scope is largely limited to this. However, since the […]
Effects of entrapment, anger, psychological flexibility, and self-compassion on the ward climate and reactive aggression in forensic psychiatric hospital patients
This study aimed to investigate the double mediation effect of entrapment and anger, as well as the moderated mediation effect of psychological flexibility and self-compassion on the relationship between the forensic psychiatric hospital ward climate and reactive aggression perceived by patients. A self-reporting method was used to measure ward climate, entrapment, anger, reactive aggression, psychological […]
The violence profile of male mentally disordered offenders in a high secure unit in Turkiye
The severity of the offense was highest in the schizophrenia group and lowest in the ID group.The existence of comorbid substance misuse in the intellectual disability group and the existence of antisocial personality disorder in the BD group was associated with increased severity of offenses.The existence of comorbid personality disorder, substance misuse in the past […]

Cocaine and the port: Utopias of security, urban relations, and displacement of policing efforts in the port of Piraeus
In large commercial seaports policing and security efforts to counter the drug trade, especially cocaine, do not appear to be effective beyond a mere displacement effect. In the port of Piraeus, Greece, (perceived) rising quantities of cocaine have led to calls for further securitisation of the port to curb illicit trafficking. This article will present […]
Individual and environmental contributors to psychological distress during imprisonment
People in prison bear a higher burden of psychiatric morbidity compared with the general population. This study examined the extent to which individual and environmental factors contribute to poor mental health during imprisonment. Participants comprised 1296 randomly selected adults in 15 Belgian prisons. Psychological distress was more common in women than men and peaked during […]
Origin stories: Framing 25 years of Dutch political discourse on child sexual exploitation by tourists and travelers
Sexual exploitation of children in the context of travel and tourism (SECTT) has been described as a serious and growing problem. This study critically analyzes political debates and policy measures proposed by the Dutch government between 1995 and 2020 to combat SECTT. To understand how SECTT is framed in Dutch political discourse, Bacchi's ‘what's the […]

Correction to “Gentrification’s association with police violence and the moderating effects of race” by Harmon-Darrow et al. (2023). 2 May 2024
Reports an error in "Gentrification’s association with police violence and the moderating effects of race" by Caroline Harmon-Darrow, Hyun-Jin Jun and Charlotte Lyn Bright (Psychology of Violence, 2023[May], Vol 13[3], 183-193). In the article, corrections to some findings were needed. For the Gentrification Revitalization × Race and the Gentrification Disruption × Race interactions (reported in […]
Perceived victimhood shapes support for interpartisan political violence in the United States. 21 March 2024
Objective: Understanding the drivers of political violence is critical, given the destructive consequences it has on the fabric of society. Prior work has established the importance of situational and dispositional predictors of political violence, such as search for significance and meaning and experiencing trauma. However, these predictors do not fully account for one of its […]
Sexual victimization of autistic college students. 18 March 2024
Objective: Researchers have demonstrated a link between autism and victimization, but less research has explored rates of sexual victimization among autistic college students. Informed by lifestyle-routine activity theory, certain features of autism may enhance vulnerability to sexual victimization and may lead autistic individuals to be targeted by potential perpetrators. Method: Using data from the American […]

Extended observation of reduced methamphetamine use with combined naltrexone plus bupropion in the ADAPT‐2 trial 10 June 2024
Addiction, EarlyView.
Michael J. Li, Brendon Chau, Thomas Belin, Thomas Carmody, Manish K. Jha, Elise N. Marino, Madhukar Trivedi, Steven J. Shoptaw
Adopting the Berridge et al.: Framework to understand differences in the e‐cigarette policy between the Nordic countries 10 June 2024
Addiction, EarlyView.
Karl Erik Lund, Gunnar Saebo
Crafting effective regulatory policies for psychedelics: What can be learned from the case of cannabis? 7 June 2024
Addiction, EarlyView.
Christina M. Andrews, Wayne Hall, Keith Humphreys, John Marsden

App-based interventions to improve cancer outcomes rely on informational support from professionals: a systematic review 17 May 2024
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Karoline Villinger Corina Berli Urte Scholz a Department of Psychology, University of Zurich, Zurich, Switzerlandb Institute of Psychology, University of Bern, Bern, Switzerland
Tobacco use, trauma exposure and PTSD: a systematic review 7 May 2024
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Alina Shevorykin Bridget M. Hyland Daniel Robles Mengjia Ji Darian Vantucci Lindsey Bensch Hannah Thorner Matthew Marion Amylynn Liskiewicz Ellen Carl Jamie S. Ostroff Christine E. Sheffer a Department of Health Behavior, Roswell Park Comprehensive Cancer Center, Buffalo, NY, USAb Department of Psychology, Faculty of Science, University of Alberta, Edmonton, Canadac Department of Psychology, The City College of New York (CUNY), New York, NY, USAd Department of Psychiatry and Behavioral Sciences, Memorial Sloan Kettering Cancer Center, New York, NY, USA
Development of the social dimensions of health behaviour framework 29 April 2024
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Ryan E. Rhodes Mark R. Beauchamp a Behavioural Medicine Laboratory, School of Exercise Science, Physical and Health Education, University of Victoria, Victoria, BC, Canadab School of Kinesiology, University of British Columbia, Vancouver, BC, Canada

Editorial: International perspectives in public mental health 5 June 2024
Editorial: International perspectives in public mental health
Neil Quinn
Mental Health First Aid™ for Deaf communities: responses to a lack of national Deaf mental health service provision 17 May 2024
For over 15 years, Mental Health First Aid™ (MHFA) has successfully been delivered in Wales, United Kingdom, with growing interest in the MHFA programme and increasing course attendees. Trainers, aware of the need for support, know the importance of MHFA being accessible for different communities and learner groups. MHFA has always focused on increasing mental […]
Julia Terry
Prevalence of cosmetic surgery and its relationship with psychosocial status: a population based study in Sulaymaniyah, Iraq 16 May 2024
This study aims to investigate the prevalence of cosmetic surgery and its relationship with the level of mental health and socioeconomic variables in Sulaymaniyah city in Iraq. This descriptive-analytical and cross-sectional study was conducted on 941 subjects who were selected using multistage sampling method. Data were collected using a checklist as well as a questionnaire. […]
Farman Zahir Abdullah

A history of mental illness among women in the Straits Settlements in the nineteenth century 15 June 2024
History of Psychiatry, Ahead of Print. The Straits Settlements, a collective colony under the administration of British Malaya, was a very unhealthy area in the early years of the nineteenth century. One of the most common sicknesses was mental illness, which could not be cured by medicines. The number of women suffering from mental illness […]
Haszira Muhamad Yusof
Social issues relating to Vladimir Bekhterev’s concept of reflexology: a hitherto underestimated aspect of his work 12 June 2024
History of Psychiatry, Ahead of Print. This article investigates the diversity of social and political assertions in the work of Vladimir M Bekhterev. Its findings reveal that he drew social and political conclusions based on his doctrine of reflexology. Moreover, he propagated the use of statistical investigations by scientific and governmental institutions to estimate the […]
Birk Engmann
Phrenitis and the pathology of the mind in western medical thought (fifth century BCE to twentieth century cE) 11 June 2024
History of Psychiatry, Ahead of Print. Phrenitis is ubiquitous in ancient medicine and philosophy. Galen mentions the disease innumerable times, Patristic authors take it as a favourite allegory of human flaws, and no ancient doctor fails to diagnose it and attempt its cure. Yet the nature of this once famous disease has not been properly […]
Chiara Thumiger

Goodbyes without farewells under the rubble: A phenomenological study of earthquake victim’s methods of coping with ambiguous loss 8 June 2024
International Journal of Social Psychiatry, Ahead of Print. Introduction:Ambiguous loss refers to the lack of clear information about the fate of a missing person or object.Aim:This study aims to examine in-depth the experiences of earthquake victims regarding the methods of coping with the uncertain losses they experienced after the Kahramanmaraş-based earthquake disaster on February 6, […]
Kübra Gülırmak Güler
Proxy consultations for severe mental illnesses: An exploratory cross-sectional study from a tertiary care hospital 8 June 2024
International Journal of Social Psychiatry, Ahead of Print. Background:Non-adherence to medication leading to a break in continuity of care poses significant challenges in severe mental illness (SMI), leading to poor outcomes. In India, proxy consultation, wherein caregivers consult on behalf of patients, is a commonly adopted but insufficiently researched area to address these challenges.Aims:To explore […]
Prakyath Ravindranath Hegde
Association of the intergenerational structure with the onset of depressive symptoms among middle-aged and older adults in China 7 June 2024
International Journal of Social Psychiatry, Ahead of Print. Background:Chinese family structure has undergone tremendous changes over the past few decades. Moreover, the association of the intergenerational structure with depression remains controversial.Aims:This study aimed to find out the association of the intergenerational structure and the onset of depressive symptoms among Chinese middle-aged and older adults.Methods:This study […]
Jun Ma

When my neighborhood woke up: Knitting collective action in disadvantaged areas amid the 2019 Chilean uprising. 15 April 2024
October 2019 saw the birth of the largest wave of demonstrations to hit Chile in the last 50 years. Protesters, the length of the country, soon joined in, voicing a broad range of demands and driving what has been described as a true “awakening” at the local level. This local dimension of the protests—that is, […]
Clarification notice to “The geography of military occupation and its effect on Palestinian community cohesion, norms, and resistance motivation” by Penić et al. (2023). 15 April 2024
Reports a clarification to "The Geography of Military Occupation and its Effect on Palestinian Community Cohesion, Norms, and Resistance Motivation" by Sandra Penić, Johanna Ray Vollhardt, Karsten Donnay, Mai Albzour and Ravi Bhavnani (Peace and Conflict: Journal of Peace Psychology, Advanced Online Publication, Jun 22, 2023, np). The authors wish to clarify the relationship between […]
School as a contested territory for citizenship: An ethnographic study of illegal occupation and protest processes at a popular vocational education school in the chilean october. 15 April 2024
The sociopolitical crisis that flared up in Chile starting in October 2019 laid bare tensions in how different social groups understand citizenship and political mobilization. These tensions evinced clear generational differences coupled with the emergence of new forms of understanding and doing politics among youth. This article presents the results of an ethnographic study conducted […]

Coronavirus pandemic dreams in China: A qualitative research on the effect of the Wuhan lockdown on dream contents. 15 April 2024
This study investigated the “coronavirus pandemic dream” phenomenon in Chinese including residing in Wuhan city based on the continuity hypothesis, which states that dream contents reflect waking life. We analyzed the effects of lockdown due to coronavirus disease-2019 (COVID-19) on dream reported from Chinese university students and workers residing in inside and outside of Hubei […]
Dreaming about the pandemic: A thematic content analysis of COVID-19-related dreams during the outbreak in Portugal. 4 April 2024
The COVID-19 pandemic has affected the mental health of people around the world, altering sleep patterns and dream experiences. Since dream content is associated with waking-life experiences, one would expect pandemic-related concerns to pervade dreams. Building upon previous research efforts, this study aims to contribute to the ongoing debate on dream function and to address […]
Prolonged changes in the perception of dreaming behaviors resulting from the COVID-19 pandemic. 18 March 2024
Reports of changes in dreaming behaviors emerged immediately after the onset of the COVID-19 pandemic. However, it is unclear if these changes persisted long term, after initial lockdowns were lifted and people became accustomed to pandemic life. The current study measured dreaming behaviors known to have changed immediately after the pandemic onset and other behaviors […]

What to Know About Medetomidine and Drug Overdoses 14 June 2024
(MedPage Today) -- Medetomidine, an animal tranquilizer more potent than xylazine, recently appeared in drug overdoses in several states in combination with the synthetic opioid fentanyl, sparking concern among public health officials. Medetomidine...
CDC Warns of Risks for ADHD Patients After Disruption of Online Adderall Prescriber 13 June 2024
(MedPage Today) -- Disrupted access to prescription stimulants for patients with attention deficit-hyperactivity disorder (ADHD) may increase risks of injury or overdose, the CDC warned on Thursday following the indictment of executives of an online...
CDC Warns About Chocolate Brand; Raw Garlic and Acne; Odd Appeal of Cow Pedicures 13 June 2024
(MedPage Today) -- Note that some links may require registration or subscription. The CDC joined the FDA in warning about severe illnesses among consumers of Diamond Shruumz brand chocolates, gummies, and other snacks. Democrats blocked a GOP...

No Link Found Between Cannabis Decriminalisation and Psychiatric Cases - ASEAN NOW 16 June 2024
Prof. Panthep also highlighted a decrease in the proportion of psychiatric patients related to methamphetamine and other drugs since cannabis was ...
Is the current commercial model of medicinal cannabis in the best interest of patients? 16 June 2024
Hindley G, Beck K, Borgan F, et al. Psychiatric symptoms caused by cannabis constituents: a systematic review and meta‐analysis. Lancet Psychiatry ...
Rural areas suffer from psychiatric care shortage | The Courier BVHS doctor sheds light on situation 16 June 2024
They said Hancock County should have 12 psychiatrists. We are not near that,” said Steiner, a psychiatrist at the Psychiatric Center of Northwest Ohio ...

At World Health Assembly, countries agree on efforts to boost pandemic preparedness 2 June 2024
Countries on Saturday agreed to a set of key actions to better guide and coordinate international efforts in preventing, detecting, and responding to public health risks, while also committing to finalize negotiations on a global pandemic agreement within a year at the latest.
Gaza: Rafah camp attack heightens focus on dwindling health resources 28 May 2024
UN agencies on Tuesday reiterated their call for an urgent ceasefire and humanitarian access in Gaza following Israeli air strikes on Sunday that hit a camp for displaced Palestinians in Rafah, killing 45 people, according to the Hamas-run Ministry of Health.
COVID-19 eliminated a decade of progress in global level of life expectancy 24 May 2024
Data crunched by the UN World Health Organization (WHO) has revealed that the COVID-19 emergency reversed more than a decade of gains in life expectancy, reinforcing the need for countries to agree on a global pandemic treaty to protect future generations.

Webinar: Supporting a strategic approach to urban health 18 June 2024
WHO has recently released a new series of policy briefs to support strategic reflection among urban health decision-makers. Each brief focuses on a cross-cutting theme: generating and working with evidence; governance and financing; innovation; and partnerships and participation. This webinar will present the new series.
who.int
Meeting of the Expert Advisory Group on the WHO Global Code 17 June 2024
The WHO Expert Advisory Group on the relevance and effectiveness of the WHO Global Code of Practice on the International Recruitment of Health Personnel will meet from 17-18 June 2024 for the first meeting of the third review of the Code.
who.int
Launch of the WHO guideline on fiscal policies to promote healthy diets 14 June 2024
The Department of Nutrition and Food Safety (NFS) is launching its new guideline on fiscal policies to promote healthy diets. The guideline provides countries with recommendations on the measures needed to improve the food offer available to promote healthy diets. T
who.int

WHO concerned about escalating health crisis in West Bank 15 June 2024
15 June 2024, Jerusalem/Cairo/Geneva WHO remains concerned about the escalating health crisis in the occupied Palestinian territory, including the West Bank, where attacks on health infrastructure and increased restrictions on movement are obstructing access to health care. A spike in violence in the West Bank, including East Jerusalem, since the war in Gaza started has […]
World Elder Abuse Awareness Day 2024: ensuring older people’s safety in emergencies 12 June 2024
15 June 2024, Cairo, Egypt – On World Elder Abuse Awareness Day 2024, the spotlight is on older people in emergencies. Older people often face mobility issues, chronic health conditions or social isolation –some of the factors that can hinder their ability to access aid, evacuate safely or receive timely medical care and support services. […]
Unsafe food makes 100 million people ill each year in the Region 6 June 2024
6 June 2024, Cairo, Egypt – “Prepare for the unexpected” is the theme of the sixth World Food Safety Day, marked today by the United Nations. Food businesses, governments and consumers can all help prevent food contamination and foodborne illnesses. Food must be protected at every stage from production to consumption. WHO and the Food […]

Cigarette smoke alters circRNA expression in human T-cells [version 2; peer review: 2 approved with reservations] 14 June 2024
Circular RNAs (circRNAs), once thought to be a result of splicing errors, have been found to be involved in various molecular processes and the pathology of various diseases, including cancer and neurodegenerative diseases. Additionally, circRNA expression was found to be altered by lifestyle habits, such as smoking cigarettes. Past studies have revealed that the rate […]
So Jin Hong
An integrative review on physical restraint in adult critical care unit [version 2; peer review: 1 approved, 1 approved with reservations] 14 June 2024
Background Physical restraints (PRs) are frequently used in adult critical care units to protect staff and prevent self-harm, despite the fact that they represent significant safety risks. Restraint complications may have an impact on the patient’s long- and short-term outcomes. This integrative review aimed to meticulously evaluate existing evidence pertaining to physical restraint practices in […]
Janisha Kavumpurath
Mutational profile of primary clear cell renal cell carcinoma predicts recurrence and potential candidacy for adjuvant immune checkpoint inhibition [version 2; peer review: 1 approved, 1 approved with reservations] 14 June 2024
Background The risk of recurrence after nephrectomy for primary clear cell renal cell carcinoma (ccRCC) is estimated in daily practice solely based on clinical criteria. The aim of this study was to assess the prognostic relevance of common somatic mutations with respect to tumor aggressiveness and outcomes of ccRCC patients after definitive treatment. Methods Primary […]
Panagiotis J. Vlachostergios

GALENOS in the BMJ 9 June 2024
Today the British Medical Journal shared their perspective on GALENOS.
galenos.org.uk
Welcoming the New Chair and Vice-Chair of GLEAB 16 May 2024
We are delighted to welcome a brand new Chair and Vice Chair of the GLEAB.
galenos.org.uk
In Memory Of Lea Milligan 30 April 2024
Lea Milligan, CEO of MQ Mental Health Research and a founding member of the GALENOS leadership team passed away unexpectedly on the 15th of April following a sudden illness.
galenos.org.uk

Birthday Honours 2024: Ambulance Service list 14 June 2024
Recipients of the King's Ambulance Service Medal 2024.
HM Government
Medicines eligible for Northern Ireland MHRA Authorised Route 14 June 2024
Sets out medicines that can be moved to Northern Ireland to meet patient need.
HM Government
Community water fluoridation expansion in the north east of England 13 June 2024
The government is seeking views on expanding community water fluoridation schemes in the north east with new arrangements or by varying existing arrangements.
HM Government

Artificial Intelligence (AI): The Future of Data 20 May 2024
With the public release of large language models like Chat GPT putting Artificial Intelligence (AI) firmly on our radar, the...
stevemilne
Measuring wellbeing and going ‘Beyond GDP’ 9 May 2024
A new ONS publication out today, aims to give an holistic view on how society is doing, beyond purely economic measures. Here, Tim Vizard explores what we have done so far on Beyond GDP and outlines our next steps on this important work.
samcollin
Understanding the new income statistics for local areas: Different measures for better insights 30 April 2024
The ONS has been busy producing faster, more detailed statistics using new data sources. Providing clearer insights at the local level is an important aspect of this work. Ainslie Woods explains how our local income statistics compare and why they offer a complementary picture of local areas.
croydl

Increasing prevalence of type 1 diabetes in older age may be a good sign 14 June 2024
The increasing burden of a chronic disease is usually a bad sign for both health providers and the general population, but the results of our study are one of the exceptions (doi:10.1136/bmj-2023-078432). Counterintuitively, the increasing prevalence of type 1 diabetes mellitus (T1DM) we found among people aged 65 and older is a good sign.1 It […]
Jing Zhang, Yongze Li
Mifepristone: US Supreme Court rejects ban on abortion drug 14 June 2024
The US Supreme Court has unanimously rejected a case to restrict access to the abortion drug mifepristone. The Alliance for Hippocratic Medicine, an anti-abortion group in Texas, had asked the court to ban the drug and force the Food and Drug Administration to take it off the market. The case had been appealed from lower […]
Janice Hopkins Tanne
Disclosure programmes in the US—an inadequate response to medical error 14 June 2024
It’s widely accepted that communicating openly with patients after a medical error is a moral imperative, but its practice has been elusive—partly because the mechanics of the process are far from intuitive.1 In the US, an important step toward creating a systematic process for disclosing errors has been the development of communication and resolution programmes […]
Gail Mazur Handley

What's in a Name: Defining Difficult-to-Treat axSpA and PsA 14 June 2024
Ongoing efforts aim to differentiate biologically refractory cases from cases with comorbid conditions and social factors that can contribute to treatment nonresponse. Medscape Medical News
Surviving to Thriving: Enhancing QoL in Breast Cancer 14 June 2024
The growing number of breast cancer survivors highlights the need for holistic and coordinated survivorship care to help women deal with a myriad of issues. Medscape Medical News
Shift Needed in Research, Treatment, for Aging MS Population 14 June 2024
Biologic age is more important than chronological age, and both are more important than disease duration for framing the care of aging patients with multiple sclerosis. Medscape Medical News

Federal Experts Talk Bird Flu ‘What Ifs’ in WebMD Live Event 16 May 2024
WebMD brought together experts from four federal agencies to talk prevention, monitoring, and what the “what ifs” of bird flu might look like.
What’s Next in Health Care for Older Adults: Questions and Answers With John Whyte, MD 16 May 2024
As WebMD’s chief medical officer, John Whyte, MD, is in a unique position to see both the current state of medical care for America’s older adults and the way things are trending for the future. We asked him to share his insight on a few topics, along with a bit of advice.
Get the Care You Need in a COVID-19 World 16 May 2024
What to expect at the doctor’s office, hospitals, and long-term care facilities, the future of telemedicine, and how to get the best care during COVID-19.

INQUEST Newsletter: June 2024 12 June 2024
Latest news from INQUEST, covering updates on the No More Deaths campaign, a new guide on achieving racial justice at inquests, and more about our cases.
Inquest
Deaths in police custody 11 June 2024
To date there have been 1895 deaths in police custody or otherwise following contact with the police in England & Wales since 1990 Below is a breakdown of deaths in police custody or following other forms of contact with the police, as well as vehicular pursuits and road traffic incidents (RTIs) since 1990, by calendar […]
Inquest
Leila Hagmann 11 June 2024
Media and Communications Officer
Inquest