Ir J Med Sci. 2024 Apr 1. doi: 10.1007/s11845-024-03666-w. Online ahead of print.

ABSTRACT

INTRODUCTION: Glioblastoma is the most common primary brain tumor in adults. Recently, research has been published on the potential prognostic indicators associated with different types of cancer. Due to the limited availability of data investigating the relationship between the CALLY index and glioblastoma patients, we aimed to conduct this study.

MATERIALS AND METHODS: Between January 2017 and December 2023, we conducted a study on patients diagnosed with glioblastoma. We collected demographic data and routine laboratory tests at the time of admission. To calculate the CALLY index, we used the formula (albumin value × lymphocyte count) / CRP value × 104. Parameters were compared for in-hospital mortality across different groups.

RESULTS: The study analyzed 202 patients who met the inclusion criteria. Of these, 165 (81.7%) were classified as “survivors” and 37 (18.3%) as “deceased.” A comparison of hematologic parameters between the two groups showed a significantly lower CALLY index in the “deceased” group (3.05 (4.92)) compared to the “survivor” group (10.13 (13.69)) (p < 0.001). The study compared the parameters between groups with regard to in-hospital mortality.

CONCLUSIONS: Based on the results of the study, we conclude that the CALLY index can be considered an easily applicable indicator for the mortality of glioblastoma patients.

PMID:38561591 | DOI:10.1007/s11845-024-03666-w