Evidence
Ir J Med Sci. 2024 Apr 1. doi: 10.1007/s11845-024-03666-w. Online ahead of print.
ABSTRACT
INTRODUCTION: Glioblastoma is the most common primary brain tumor in adults. Recently, research has been published on the potential prognostic indicators associated with different types of cancer. Due to the limited availability of data investigating the relationship between the CALLY index and glioblastoma patients, we aimed to conduct this study.
MATERIALS AND METHODS: Between January 2017 and December 2023, we conducted a study on patients diagnosed with glioblastoma. We collected demographic data and routine laboratory tests at the time of admission. To calculate the CALLY index, we used the formula (albumin value × lymphocyte count) / CRP value × 104. Parameters were compared for in-hospital mortality across different groups.
RESULTS: The study analyzed 202 patients who met the inclusion criteria. Of these, 165 (81.7%) were classified as “survivors” and 37 (18.3%) as “deceased.” A comparison of hematologic parameters between the two groups showed a significantly lower CALLY index in the “deceased” group (3.05 (4.92)) compared to the “survivor” group (10.13 (13.69)) (p < 0.001). The study compared the parameters between groups with regard to in-hospital mortality.
CONCLUSIONS: Based on the results of the study, we conclude that the CALLY index can be considered an easily applicable indicator for the mortality of glioblastoma patients.
PMID:38561591 | DOI:10.1007/s11845-024-03666-w
Estimated reading time: 4 minute(s)
Latest: Psychiatryai.com #RAISR4D Evidence
Cool Evidence: Engaging Young People and Students in Real-World Evidence
Real-Time Evidence Search [Psychiatry]
AI Research
The effect of indicators of CALLY index on survival in glioblastoma
🌐 90 Days
AI Virtual Reality Related Evidence Matrix
- Metastatic extraneural glioblastoma diagnosed with molecular testing
- Impact of frailty on survival glioblastoma, IDH-wildtype patients
- SRSF2 promotes glioblastoma cell proliferation by inducing alternative splicing of FSP1 and inhibiting ferroptosis
- SRSF2 promotes glioblastoma cell proliferation by inducing alternative splicing of FSP1 and inhibiting ferroptosis
- Prognostic Factors for Progression-free Survival and Overall Survival After Recurrence of Glioblastoma
- Transformation of IDH-wildtype glioblastoma to gliosarcoma with features of osteosarcoma
- The Role of Fibroblast Activation Protein in Glioblastoma and Gliosarcoma: A Comparison of Tissue, 68Ga-FAPI-46 PET Data, and Survival Data
- Anti-epileptic drug use during adjuvant chemo-radiotherapy is associated with poorer survival in patients with glioblastoma: A nationwide population-based cohort study
- In situ brain tumor detection using a Raman spectroscopy system-results of a multicenter study
- Effects of Lomerizine and Its Metabolite on Glioblastoma Cells
- A prognostic neural epigenetic signature in high-grade glioma
- Corrigendum to "Zotiraciclib (TG02) for newly diagnosed glioblastoma in the elderly or for recurrent glioblastoma: The EORTC 1608 STEAM trial" [Eur J Cancer 198 (2024) 113475]
- Metal-Doping Strategy for Carbon-Based Sonosensitizer in Sonodynamic Therapy of Glioblastoma
- The impact of cancer patient pathway on timing of radiotherapy and survival: a cohort study in glioblastoma patients
- PPAR-γ agonists reactivate the ALDOC-NR2F1 axis to enhance sensitivity to temozolomide and suppress glioblastoma progression
- Effects of tumor treating fields (TTFields) on human mesenchymal stromal cells
- Effects of tumor treating fields (TTFields) on human mesenchymal stromal cells
- The Roles of AGTRAP, ALKBH3, DIVERSIN, NEDD8 and RRM1 in Glioblastoma Pathophysiology and Prognosis
- Lomustine with or without reirradiation for first progression of glioblastoma, LEGATO, EORTC-2227-BTG: study protocol for a randomized phase III study
- Cadherin Expression Profiles Define Glioblastoma Differentiation and Patient Prognosis
- Extracellular vesicles secreted by 3D tumor organoids are enriched for immune regulatory signaling biomolecules compared to conventional 2D glioblastoma cell systems
- Isocitrate Dehydrogenase 1/2 Wildtype Adult Astrocytoma with WHO Grade 2/3 Histological Features: Molecular Re-Classification, Prognostic Factors, Clinical Outcomes
- Epidemiology of malignant gliomas in Iran: first report of Iranian National Population-based Cancer Registry, 2009-2017
- Methylthioadenosine phosphorylase and p16 as surrogate diagnostic markers for CDKN2A homozygous deletion in brain tumors
- Lineage specification in glioblastoma is regulated by METTL7B
- Effects of Tetrahydrolipstatin on Glioblastoma in Mice: MRI-Based Morphologic and Texture Analysis Correlated with Histopathology and Immunochemistry Findings-A Pilot Study
- Activation of the mevalonate pathway in response to anti-cancer treatments drives glioblastoma recurrences through activation of Rac-1
- Activation of the mevalonate pathway in response to anti-cancer treatments drives glioblastoma recurrences through activation of Rac-1
- Indirect functional connectivity does not predict overall survival in glioblastoma
- Expression of concern: A hypoxia-dissociable siRNA nanoplatform for synergistically enhanced chemo-radiotherapy of glioblastoma
- PRMT6-mediated transcriptional activation of ythdf2 promotes glioblastoma migration, invasion, and emt via the wnt-b-catenin pathway
- Deuterium metabolic imaging differentiates glioblastoma metabolic subtypes and detects early response to chemoradiotherapy
- Expression of concern: A hypoxia-dissociable siRNA nanoplatform for synergistically enhanced chemo-radiotherapy of glioblastoma
- Higher YAP1 Levels Are Associated With Shorter Survival of Patients With Low Grade Astrocytoma
- Radiomics and visual analysis for predicting success of transplantation of heterotopic glioblastoma in mice with MRI
- Radiomics and visual analysis for predicting success of transplantation of heterotopic glioblastoma in mice with MRI
- Autophagy-related CMTM6 promotes glioblastoma progression by activating Wnt/b-catenin pathway and acts as an onco-immunological biomarker
- Predicting Survival Using Whole-Liver MRI Radiomics in Patients with Hepatocellular Carcinoma After TACE Refractoriness
- ECG-surv: A deep learning-based model to predict time to 1-year mortality from 12-lead electrocardiogram
- ECG-surv: A deep learning-based model to predict time to 1-year mortality from 12-lead electrocardiogram
- Relationship between nutrition indicators and pneumonia risk among stable schizophrenia patients: a retrospective study
- L-RNA aptamer-based CXCL12 inhibition combined with radiotherapy in newly-diagnosed glioblastoma: dose escalation of the phase I/II GLORIA trial
- L-RNA aptamer-based CXCL12 inhibition combined with radiotherapy in newly-diagnosed glioblastoma: dose escalation of the phase I/II GLORIA trial
- Extraction of Unstructured Electronic Health Records to Evaluate Glioblastoma Treatment Patterns
- Discovery of Potent Multikinase Type-II Inhibitors Targeting CDK5 in the DFG-out Inactive State with Promising Potential against Glioblastoma
- Speeding Up and Improving Image Quality in Glioblastoma MRI Protocol by Deep Learning Image Reconstruction
- The mitochondria-related gene risk mode revealed p66Shc as a prognostic mitochondria-related gene of glioblastoma
- The mitochondria-related gene risk mode revealed p66Shc as a prognostic mitochondria-related gene of glioblastoma
- Determining the relationship of p16INK4a and additional molecular markers of aging with clinical frailty in hematologic malignancy
- Protective effects of silymarin in glioblastoma cancer cells through redox system regulation
- Rest-Activity Rhythm Differences in Acute Rehabilitation Between Poststroke Patients and Non-Brain Disease Controls: Comparative Study
- Rest-Activity Rhythm Differences in Acute Rehabilitation Between Poststroke Patients and Non-Brain Disease Controls: Comparative Study
- Prognostic implications of delirium after Left Ventricular Assist Device (LVAD) implantation: A retrospective study
- Identification of a single-dose, low flip angle based CBV threshold for fractional tumor burden (FTB) mapping in recurrent glioblastoma
- The relationship between a comprehensive index of prosperity and suicide rates in former Soviet countries, including a comparison with European and Asian countries: Discussion from a new perspective
- Clinical implementation of a commercial synthetic computed tomography solution for radiotherapy treatment of glioblastoma
- Patient with mediastinal carcinoma of unknown primary with RET fusion achieves durable response with RET inhibition
- A rare case of atypical intradural extramedullary glioblastoma diagnosed utilizing next-generation sequencing and methylation profiling: illustrative case
- Metabolic models predict fotemustine and the combination of eflornithine/rifamycin and adapalene/cannabidiol for the treatment of gliomas
- Prognostic Analysis Combining Histopathological Features and Clinical Information to Predict Colorectal Cancer Survival from Whole-Slide Images
- Deep-learning-based stock market prediction incorporating ESG sentiment and technical indicators
- Risk factors of reattempt among suicide attempters in South Korea: A nationwide retrospective cohort study
- Data Preprocessing Techniques for Artificial Learning (AI)/Machine Learning (ML)-Readiness: Systematic Review of Wearable Sensor Data in Cancer Care
- Automatic brain-tumor diagnosis using cascaded deep convolutional neural networks with symmetric U-Net and asymmetric residual-blocks
Evidence Blueprint
The effect of indicators of CALLY index on survival in glioblastoma
☊ AI-Driven Related Evidence Nodes
(recent articles with at least 5 words in title)
More Evidence
The effect of indicators of CALLY index on survival in glioblastoma
🌐 365 Days
AI Virtual Reality Related Evidence Matrix
- Metastatic extraneural glioblastoma diagnosed with molecular testing
- Prognostic Value of TSPO PET Before Radiotherapy in Newly Diagnosed IDH-Wild-Type Glioblastoma
- Impact of frailty on survival glioblastoma, IDH-wildtype patients
- Glioblastoma with Probable Intratumoral Adenocarcinoma Metastasis: A Rare Report with Review of Literature
- Glioblastoma with Probable Intratumoral Adenocarcinoma Metastasis: A Rare Report with Review of Literature
- SRSF2 promotes glioblastoma cell proliferation by inducing alternative splicing of FSP1 and inhibiting ferroptosis
- SRSF2 promotes glioblastoma cell proliferation by inducing alternative splicing of FSP1 and inhibiting ferroptosis
- Prognostic Factors for Progression-free Survival and Overall Survival After Recurrence of Glioblastoma
- Downregulation of MGMT expression by targeted editing of DNA methylation enhances temozolomide sensitivity in glioblastoma
- A phase Ib/II randomized, open-label drug repurposing trial of glutamate signaling inhibitors in combination with chemoradiotherapy in patients with newly diagnosed glioblastoma: the GLUGLIO trial protocol
- Dexamethasone and overall survival and progression free survival in patients with newly diagnosed glioblastoma: a meta-analysis
- Transformation of IDH-wildtype glioblastoma to gliosarcoma with features of osteosarcoma
- The Role of Fibroblast Activation Protein in Glioblastoma and Gliosarcoma: A Comparison of Tissue, 68Ga-FAPI-46 PET Data, and Survival Data
- Circulating extracellular vesicles as biomarker for diagnosis, prognosis and monitoring in glioblastoma patients
- Feasibility and tolerability of trofosfamide and etoposide in progressive glioblastoma
- Anti-epileptic drug use during adjuvant chemo-radiotherapy is associated with poorer survival in patients with glioblastoma: A nationwide population-based cohort study
- In situ brain tumor detection using a Raman spectroscopy system-results of a multicenter study
- Effects of Lomerizine and Its Metabolite on Glioblastoma Cells
- Iron-based biomarkers for personalizing pharmacological ascorbate therapy in glioblastoma: insights from a phase 2 clinical trial
- A prognostic neural epigenetic signature in high-grade glioma
- MGMT methylation pattern of long-term and short-term survivors of glioblastoma reveals CpGs of the enhancer region to be of high prognostic value
- Corrigendum to "Zotiraciclib (TG02) for newly diagnosed glioblastoma in the elderly or for recurrent glioblastoma: The EORTC 1608 STEAM trial" [Eur J Cancer 198 (2024) 113475]
- Potential of pre-operative MRI features in glioblastoma to predict for molecular stem cell subtype and patient overall survival
- Tumor size, treatment patterns, and survival in neuro-oncology patients before and during the COVID-19 pandemic
- Status epilepticus in patients with glioblastoma: Clinical characteristics, risk factors, and epileptological outcome
- Metal-Doping Strategy for Carbon-Based Sonosensitizer in Sonodynamic Therapy of Glioblastoma
- The impact of cancer patient pathway on timing of radiotherapy and survival: a cohort study in glioblastoma patients
- Temporal change of DNA methylation subclasses between matched newly diagnosed and recurrent glioblastoma
- PPAR-γ agonists reactivate the ALDOC-NR2F1 axis to enhance sensitivity to temozolomide and suppress glioblastoma progression
- Effects of tumor treating fields (TTFields) on human mesenchymal stromal cells
- Effects of tumor treating fields (TTFields) on human mesenchymal stromal cells
- Low rCBV values in glioblastoma tumor progression under chemoradiotherapy
- Cluster-based prognostication in glioblastoma: Unveiling heterogeneity based on diffusion and perfusion similarities
- Haploinsufficiency of phosphodiesterase 10A activates PI3K/AKT signaling independent of PTEN to induce an aggressive glioma phenotype
- Nuclear Glycoprotein A Repetitions Predominant (GARP) Is a Common Trait of Glioblastoma Stem-like Cells and Correlates with Poor Survival in Glioblastoma Patients
- "De novo replication repair deficient glioblastoma, IDH-wildtype" is a distinct glioblastoma subtype in adults that may benefit from immune checkpoint blockade
- Characteristics and Prognosis of Tumor-Related Epilepsy During Tumor Evolution in Patients With IDH Wild-Type Glioblastoma
- Prognostic Value of BRAF Mutation in Glioblastoma
- Marizomib for patients with newly diagnosed glioblastoma: a randomized phase 3 trial
- The Roles of AGTRAP, ALKBH3, DIVERSIN, NEDD8 and RRM1 in Glioblastoma Pathophysiology and Prognosis
- Association of MGMT Promoter and Enhancer Methylation with Genetic Variants, Clinical Parameters, and Demographic Characteristics in Glioblastoma
- Real-time monitoring of abnormal mitochondrial viscosity in glioblastoma with a novel mitochondria-targeting fluorescent probe
- Hermite-scan imaging for differentiating glioblastoma from normal brain: Simulations and ex vivo studies for applications in intra-operative tumor identificationa)
- A clinically applicable connectivity signature for glioblastoma includes the tumor network driver CHI3L1
- Epigenetic profiling reveals a strong association between lack of 5-ALA fluorescence and EGFR amplification in IDH-wildtype glioblastoma
- Autophagy Inhibition with Chloroquine Increased Pro-Apoptotic Potential of New Aziridine-Hydrazide Hydrazone Derivatives against Glioblastoma Cells
- Autophagy Inhibition via Hydroxychloroquine or 3-Methyladenine Enhances Chemotherapy-Induced Apoptosis in Neuro-Blastoma and Glioblastoma
- Lomustine with or without reirradiation for first progression of glioblastoma, LEGATO, EORTC-2227-BTG: study protocol for a randomized phase III study
- Unveiling The Neuropathology Tumour Landscape: 10-Year Statistical Analysis With Global Comparison - Single Centre Experience
- Cadherin Expression Profiles Define Glioblastoma Differentiation and Patient Prognosis
- Deciphering sources of PET signals in the tumor microenvironment of glioblastoma at cellular resolution
- The genomic alterations in glioblastoma influence the levels of CSF metabolites
- Glycation Interferes with the Expression of Sialyltransferases and Leads to Increased Polysialylation in Glioblastoma Cells
- Repurposing of Zika virus live-attenuated vaccine (ZIKV-LAV) strains as oncolytic viruses targeting human glioblastoma multiforme cells
- Extracellular vesicles secreted by 3D tumor organoids are enriched for immune regulatory signaling biomolecules compared to conventional 2D glioblastoma cell systems
- Isocitrate Dehydrogenase 1/2 Wildtype Adult Astrocytoma with WHO Grade 2/3 Histological Features: Molecular Re-Classification, Prognostic Factors, Clinical Outcomes
- Computational Assessment of Spectral Heterogeneity within Fresh Glioblastoma Tissue Using Raman Spectroscopy and Machine Learning Algorithms
- Progesterone Receptor Membrane Component 1 (PGRMC1) Modulates Tumour Progression, the Immune Microenvironment and the Response to Therapy in Glioblastoma
- Epidemiology of malignant gliomas in Iran: first report of Iranian National Population-based Cancer Registry, 2009-2017
- Extracellular-Vesicle-Based Cancer Panels Diagnose Glioblastomas with High Sensitivity and Specificity
- Magnetic resonance spectroscopic correlates of progression free and overall survival in "glioblastoma, IDH-wildtype, WHO grade-4"
- Methylthioadenosine phosphorylase and p16 as surrogate diagnostic markers for CDKN2A homozygous deletion in brain tumors
- Lineage specification in glioblastoma is regulated by METTL7B
- Rare germline variants in POLE and POLD1 encoding the catalytic subunits of DNA polymerases ε and δ in glioma families