Delirium – Psychiatry AI: Real-Time AI Scoping Review

Delirium RAISR4D

25/08/2026

Long-term mortality in patients admitted acutely for chronic liver disease in England: A national cohort study

Eur J Intern Med. 2026 Aug 24:107142. doi: 10.1016/j.ejim.2026.107142. Online ahead of print.ABSTRACTBACKGROUND: Chronic liver disease (CLD) is a growing global health concern. Many CLD...

Delirium RAISR4D

25/08/2026

Albumin priming prior to an exchange transfusion: Is it time to prime for neuroprotection?

Semin Perinatol. 2026 Aug 24:152292. doi: 10.1016/j.semperi.2026.152292. Online ahead of print.ABSTRACTAlbumin is the crux of the exchangeable (i.e., miscible) bilirubin pool, controlling via its high...

Delirium RAISR4D

25/08/2026

Duration of Intraoperative Cerebral Oxygen Desaturation and Postoperative Delirium in Elderly Patients Undergoing Major Noncardiac Surgery: A Prospective Observational Study

J Cardiothorac Vasc Anesth. 2026 Aug 1:S1053-0770(26)00642-7. doi: 10.1053/j.jvca.2026.07.052. Online ahead of print.ABSTRACTOBJECTIVE: To investigate whether the cumulative duration of a clinically significant decline in...

Delirium RAISR4D

25/08/2026

Chemogenetic manipulation of mPFC neurons counteracts cognitive deficits but leaves sleep disturbances unaffected in a mouse model of chronic intermittent hypoxia

J Neurosci. 2026 Aug 24:e0256262026. doi: 10.1523/JNEUROSCI.0256-26.2026. Online ahead of print.ABSTRACTChronic intermittent hypoxia (CIH), a hallmark of obstructive sleep apnea, gives rise to cognitive deficits...

Delirium RAISR4D

25/08/2026

Cerebrovascular injury following manual strangulation and subsequent cervical manipulation: challenges in attribution and imaging decisions

BMJ Case Rep. 2026 Aug 24;19(8):e275291. doi: 10.1136/bcr-2026-275291.ABSTRACTCervical artery dissection (CAD) causes approximately 2% of ischaemic strokes overall but up to 25% in adults younger...

Delirium RAISR4D

25/08/2026

The effect of self-care management with the look after yourself (LAY) model on self-efficacy and functional status of stroke patients

J Vasc Nurs. 2026 Sep;44(3):223-229. doi: 10.1016/j.jvn.2026.07.002. Epub 2026 Jul 17.ABSTRACTBACKGROUND: Stroke is a leading cause of death and long-term disability worldwide. Self-efficacy is a...

Delirium RAISR4D

25/08/2026

Redo-Transcatheter Aortic Valve Replacement With Self-Expanding Valves: A U.S. Registry Analysis

JACC Cardiovasc Interv. 2026 Aug 24;19(16):2204-2216. doi: 10.1016/j.jcin.2026.07.009.ABSTRACTBACKGROUND: Redo-transcatheter aortic valve replacement (TAVR) for failed transcatheter heart valves is expected to increase, but data on...

Delirium RAISR4D

25/08/2026

Burden, unmet healthcare and associated disabilities among people with prevalent stroke in tea-tribe communities of Cachar district, Assam state, Northeast India: a cross-sectional study

BMJ Open. 2026 Aug 24;16(8):e114655. doi: 10.1136/bmjopen-2025-114655.ABSTRACTBACKGROUND: Tea-tribe communities in Assam face a substantial and under-recognised burden of stroke, shaped by socioeconomic marginalisation, limited access...

Delirium RAISR4D

25/08/2026

Use of antipsychotics in adult palliative care: a scoping review protocol

BMJ Open. 2026 Aug 24;16(8):e121834. doi: 10.1136/bmjopen-2026-121834.ABSTRACTINTRODUCTION: Antipsychotics are commonly used in adult palliative care practice due to their multiple therapeutic indications. However, the available...

Delirium RAISR4D

25/08/2026

Retinal microstructural alterations as early phenotypes of depression in radiogenomics analysis

J Affect Disord. 2026 Aug 24:122413. doi: 10.1016/j.jad.2026.122413. Online ahead of print.ABSTRACTBACKGROUND: With the increasing prevalence of depression, there is an urgent clinical need for...

Delirium RAISR4D

25/08/2026

Effect of Dementia on Risk Factors for Postoperative Delirium in Older Patients Undergoing Total Knee Arthroplasty: A Retrospective Cohort Study Based on a Large National Dataset

J Arthroplasty. 2026 Aug 24:S0883-5403(26)00894-6. doi: 10.1016/j.arth.2026.08.031. Online ahead of print.ABSTRACTBACKGROUND: Postoperative delirium (POD) is a frequent and serious complication following total knee arthroplasty (TKA),...

Delirium RAISR4D

25/08/2026

Re-thinking Organ Donation: Structural development, Multiprofessional Collaboration, and Data-Driven Research

Dtsch Med Wochenschr. 2026 Aug;151(17):954-960. doi: 10.1055/a-2679-0633. Epub 2026 Aug 24.ABSTRACTThe number of organ donations in Germany still does not meet the actual demand of...

Delirium RAISR4D

25/08/2026

Cholesterol dysregulation in APOE4 astrocytes promotes α-synuclein pathology in miBrains

Cell Stem Cell. 2026 Aug 24:S1934-5909(26)00302-4. doi: 10.1016/j.stem.2026.08.001. Online ahead of print.ABSTRACTThe pathological hallmarks of neurodegeneration are the aberrant post-translational modification and aggregation of proteins....

Delirium RAISR4D

25/08/2026

Genetic backround of developmental and epileptic encephalopathies is wider than monogenic aetiologies: Clinical and prognostic implications

Seizure. 2026 Aug 13;142:58-59. doi: 10.1016/j.seizure.2026.08.010. Online ahead of print.NO ABSTRACTPMID:42636611 | DOI:10.1016/j.seizure.2026.08.010

Delirium RAISR4D

25/08/2026

Quality Evaluation Using the Mobile App Rating Scale for Speech Therapy in Parkinson Disease: Systematic Search and Evaluation

JMIR Form Res. 2026 Aug 24;10:e72214. doi: 10.2196/72214.ABSTRACTBACKGROUND: As the global population ages, Parkinson disease (PD) has emerged as the second most prevalent neurodegenerative condition...

Delirium RAISR4D

24/08/2026

PTPRO inhibitor alleviates cytoskeletal rearrangement and pyroptosis in brain microvascular endothelial cells in sepsis-associated encephalopathy via PI3K/AKT-related signaling

Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi. 2026 Aug;42(8):692-700.ABSTRACTObjective Sepsis-associated encephalopathy (SAE) is a common and severe complication of sepsis and is...

Delirium RAISR4D

24/08/2026

Glial ceramide orchestrates lipid homeostasis and age-dependent motor function

Dis Model Mech. 2026 Aug 24:dmm.052840. doi: 10.1242/dmm.052840. Online ahead of print.ABSTRACTGlial cells have emerged as equal partners to neurons in the development and maintenance...

Delirium RAISR4D

24/08/2026

Identification of Risk Factors and Development of a Prediction Model for Recovery Room Delirium Following Transurethral Resection of the Prostate

Clin Interv Aging. 2026 Aug 19;21:612965. doi: 10.2147/CIA.S612965. eCollection 2026.ABSTRACTPURPOSE: To identify independent risk factors for recovery room delirium (RRD) in patients undergoing transurethral resection...

Delirium RAISR4D

24/08/2026

Global Burden and Temporal Trends of Brain and Central Nervous System Tumors in Children and Adolescents: A Systematic Analysis for the Global Burden of Disease Study 2021

Cancer Innov. 2026 Aug 23;5(4):e70079. doi: 10.1002/cai2.70079. eCollection 2026 Aug.ABSTRACTBACKGROUND: Central nervous system (CNS) tumors pose major global health challenges. Previous studies often assessed all-age...

Delirium RAISR4D

24/08/2026

Neuroprotective Potential of Terpenoids: A Promising Avenue in Neurology

Mini Rev Med Chem. 2026 Aug 1. doi: 10.2174/0113895575463965260727105312. Online ahead of print.ABSTRACTNeurodegenerative diseases are progressive disorders characterised by the deterioration of neuronal structure and...

Delirium RAISR4D

24/08/2026

Current Targeted Nanoparticle Therapy for Alzheimer’s Disease: Current Advances and Future Prospects

Curr Neurovasc Res. 2026 Aug 1. doi: 10.2174/0115672026471444260724103751. Online ahead of print.ABSTRACTBACKGROUND: The effects of Alzheimer's disease (AD) on society are profound. The blood-brain barrier...

Delirium RAISR4D

24/08/2026

Machine learning-based prediction of incident delirium after a 24-hour landmark in critically ill patients with acute pancreatitis: Model development and external validation using the MIMIC-IV and eICU databases

Sci Prog. 2026 Jul-Sep;109(3):368504261481919. doi: 10.1177/00368504261481919. Epub 2026 Aug 23.ABSTRACTObjectiveTo develop, internally validate, and preliminarily externally validate a model predicting incident delirium after the first...

Delirium RAISR4D

24/08/2026

Exploring a Facilitator-Enabled Flexible iSupport for Dementia Program: An Internal Pilot Mixed-Methods Study

Nurs Open. 2026 Aug;13(8):e70774. doi: 10.1002/nop2.70774.ABSTRACTAIMS: To assess the feasibility, fidelity and preliminary impact of a facilitator-enabled flexible iSupport for dementia program for family carers...

Delirium RAISR4D

24/08/2026

Mechanisms of Acupuncture on the Neurovascular Unit in Migraine: A Narrative Review

Eur J Neurol. 2026 Aug;33(8):e70730. doi: 10.1111/ene.70730.ABSTRACTOBJECTIVE: The neurovascular unit (NVU) is a core structural and functional entity involved in migraine pathogenesis. Acupuncture may exert...

Delirium RAISR4D

24/08/2026

Phenobarbital Versus Benzodiazepine-Based Pathways for Alcohol Withdrawal Syndrome in Critically Ill Adults: A Systematic Review and Meta-Analysis

Pharmacotherapy. 2026 Sep;46(9):e70197. doi: 10.1002/phar.70197.ABSTRACTOBJECTIVE: To compare outcomes of phenobarbital-based versus benzodiazepine-based pathways for alcohol withdrawal syndrome (AWS) in critically ill adults and evaluate whether...

Delirium RAISR4D

23/08/2026

Friedelin alleviates cerebral ischemia/reperfusion injury by controlling microglial phenotypes through the reduction of TLR4-mediated ferroptosis

J Pharmacol Sci. 2026 Oct;162(2):162-178. doi: 10.1016/j.jphs.2026.07.004. Epub 2026 Jul 23.ABSTRACTFriedelin (FD), a natural pentacyclic triterpene, exerts neuroprotective effects, but its role in cerebral ischemic...

Delirium RAISR4D

23/08/2026

Methylophiopogonone A alleviates ischemic brain injury by inhibiting macrophage M1 activation and inflammation through NF-kappaB signaling pathway

J Pharmacol Sci. 2026 Oct;162(2):117-129. doi: 10.1016/j.jphs.2026.07.005. Epub 2026 Jul 30.ABSTRACTIschemic stroke (IS) triggers neuroinflammation that drives neuronal dysfunction and tissue injury. Resident central nervous...

Delirium RAISR4D

23/08/2026

The relationship between plasma FOXO3 and cognitive impairment and depressive symptoms in cerebral small vessel disease

Exp Gerontol. 2026 Aug 22:113296. doi: 10.1016/j.exger.2026.113296. Online ahead of print.ABSTRACTBACKGROUND AND PURPOSE: Cerebral small vessel disease (CSVD) is a leading cause of post-stroke cognitive...

Delirium RAISR4D

23/08/2026

Ergothioneine as an Emerging Food-Derived Bioactive Compound Protecting against Age-related Diseases: Issues Needing More Research

Am J Clin Nutr. 2026 Aug 22:101488. doi: 10.1016/j.ajcnut.2026.101488. Online ahead of print.ABSTRACTErgothioneine (ET) is a chemically-stable, tasteless, odourless, highly water-soluble diet-derived compound that is...

Delirium RAISR4D

23/08/2026

Risk Prediction Models for Hepatic Encephalopathy Post-Transjugular Intrahepatic Portosystemic Shunt: a Systematic Review and Critical Appraisal

JHEP Rep. 2026 Aug 22:102006. doi: 10.1016/j.jhepr.2026.102006. Online ahead of print.ABSTRACTBACKGROUND & AIMS: Transjugular Intrahepatic Portosystemic Shunt (TIPS) is an established treatment for portal hypertension...

Delirium RAISR4D

23/08/2026

Tumor microenvironment-remodeling cell membrane biomimetic nanoplatform for activated imaging and cascade-amplified treatment of breast cancer

J Adv Res. 2026 Aug 22:S2090-1232(26)00685-5. doi: 10.1016/j.jare.2026.08.053. Online ahead of print.ABSTRACTINTRODUCTION: Strategic harnessing and modulation of the tumor microenvironment (TME) can overcome its inherent...

Delirium RAISR4D

23/08/2026

Low expression of PDGFR-beta impairs the blood-brain barrier and accelerates cellular aging in the hippocampal region

Biochem Biophys Res Commun. 2026 Aug 18;834:154456. doi: 10.1016/j.bbrc.2026.154456. Online ahead of print.ABSTRACTBACKGROUND: Platelet-Derived Growth Factor Receptor Beta (PDGFR-β), a key marker of cerebrovascular pericytes,...

Delirium RAISR4D

23/08/2026

Associations between EEG measures and clinical severity in CDKL5 deficiency disorder

Clin Neurophysiol. 2026 Aug 19;191:2112378. doi: 10.1016/j.clinph.2026.2112378. Online ahead of print.ABSTRACTOBJECTIVE: Prior work has shown that quantitative EEG and evoked potentials (EPs) may be useful...

Delirium RAISR4D

23/08/2026

Mental Health Disorders and Dementia in Ecuadorian Older Adults: A Nationwide Cross-Sectional Study

Arch Med Res. 2026 Aug 22;57(7):103504. doi: 10.1016/j.arcmed.2026.103504. Online ahead of print.ABSTRACTBACKGROUND: Older adults are vulnerable to mental health disorders, and hospitalization typically indicates severity....

Delirium RAISR4D

23/08/2026

Peptide-functionalized magnetic nanobeads for EpCAM-targeted CTC isolation and immunotherapy efficacy evaluation in liver cancer

Talanta. 2026 Aug 18;312(Pt B):130466. doi: 10.1016/j.talanta.2026.130466. Online ahead of print.ABSTRACTPrimary liver cancer lacks robust biomarkers for anti-PD-1/PD-L1 therapy. Methods: We engineered peptide-functionalized magnetic nanobeads...

Delirium RAISR4D

23/08/2026

Rehabilitation needs of older adults with cognitive impairment following ischemic stroke: a qualitative study

Ann Med. 2026 Dec;58(1):2715257. doi: 10.1080/07853890.2026.2715257. Epub 2026 Aug 22.ABSTRACTAIM: To explore the self-reported experiences of older adults with post-stroke cognitive impairment following ischemic stroke...

Delirium RAISR4D

23/08/2026

Revisiting the cortical architecture of language: evidence from left-hemisphere gliomas

Cereb Cortex. 2026 Aug 1;36(8):bhag112. doi: 10.1093/cercor/bhag112.ABSTRACTCurrent wisdom of the organization of language in the brain has been shaped primarily by evidence from people with...

Delirium RAISR4D

23/08/2026

Efficacy and safety of fenfluramine in Dravet syndrome: The impact of patient clinical characteristics

Epilepsia Open. 2026 Aug 22. doi: 10.1002/epi4.70340. Online ahead of print.ABSTRACTOBJECTIVE: To assess the efficacy and safety of fenfluramine in patients with Dravet syndrome (DS)...

Delirium RAISR4D

23/08/2026

Prediction of subsequent seizures after acute symptomatic seizures in critically ill children: A clinical-electroencephalographic model

Epilepsia. 2026 Aug 22. doi: 10.1002/epi.70452. Online ahead of print.ABSTRACTOBJECTIVE: We aimed to determine the risk of subsequent seizure or epilepsy diagnosis after acute symptomatic...

Delirium RAISR4D

23/08/2026

Microglial Immunometabolic Remodeling After Ischemic Stroke: The Interplay Between Mitochondrial Stress and the Ischemic Microenvironment

Transl Stroke Res. 2026 Aug 22;17(5):100. doi: 10.1007/s12975-026-01492-z.ABSTRACTFollowing ischemic stroke, marked alterations in the local metabolic and inflammatory milieu of the brain drive immunometabolic remodeling...

Delirium RAISR4D

22/08/2026

Risk stratification in older adults with rib fractures: Performance of the STUMBL score

Injury. 2026 Aug 19:113601. doi: 10.1016/j.injury.2026.113601. Online ahead of print.ABSTRACTINTRODUCTION: Rib fractures are the most common injury following blunt chest trauma, with around 10% of...

Delirium RAISR4D

22/08/2026

Quercetin for brain diseases: Preclinical evidence and therapeutic potentials

J Integr Med. 2026 Jul 27:S2095-4964(26)00093-2. doi: 10.1016/j.joim.2026.07.009. Online ahead of print.ABSTRACTThis review compiles the preclinical evidence on the therapeutic effects of quercetin in brain...

Delirium RAISR4D

22/08/2026

Improvement in neuropsychological function with memantine treatment among patients with systemic lupus erythematosus: a phase 2 randomised placebo-controlled clinical trial

Ann Rheum Dis. 2026 Aug 21:S0003-4967(26)00436-X. doi: 10.1016/j.ard.2026.07.015. Online ahead of print.ABSTRACTOBJECTIVES: Neuropsychological symptoms are common, disabling manifestations of systemic lupus erythematosus (SLE) that can...

Delirium RAISR4D

22/08/2026

Retraction notice to “research on the shared function of central neurons and breast cancer based on gene expression profile data mining: The role of EMID1 protein antibody expression” [Int. J. Biol. Macromol. 277 (2024) 134393]

Int J Biol Macromol. 2026 Aug 21:154056. doi: 10.1016/j.ijbiomac.2026.154056. Online ahead of print.NO ABSTRACTPMID:42629204 | DOI:10.1016/j.ijbiomac.2026.154056

Delirium RAISR4D

22/08/2026

Neurobiological Correlates of Cancer-Related Fatigue in Chemotherapy-Naïve Breast Cancer: A Retrospective Longitudinal [18F]FDG PET/CT Study

AJNR Am J Neuroradiol. 2026 Aug 21:ajnr.A9602. doi: 10.3174/ajnr.A9602. Online ahead of print.ABSTRACTBACKGROUND: Cancer-related fatigue (CRF) is a prevalent and debilitating symptom in cancer patients,...

Delirium RAISR4D

22/08/2026

Repeated intravenous thrombolysis for ischaemic stroke with medium to large vessel occlusion presenting within 4.5 hours of onset with tenecteplase in China (RITIS-TNK2): protocol for a prospective, randomised, open-label, blinded assessment of outcome and multicentre study

BMJ Open. 2026 Aug 21;16(8):e120918. doi: 10.1136/bmjopen-2026-120918.ABSTRACTINTRODUCTION: Recanalisation rates following standard intravenous thrombolysis (IVT) for acute ischaemic stroke due to medium or large vessel occlusion...

Delirium RAISR4D

22/08/2026

Chemokine receptor CX3CR1 modulates microglial activity through Tau and amyloid-β interactions in Alzheimer’s disease

Adv Immunol. 2026;171:83-108. doi: 10.1016/bs.ai.2025.11.002. Epub 2025 Dec 1.ABSTRACTAlzheimer's disease is one of the most prevalent forms of dementia characterized by neurocognitive decline. Key proteins...

Delirium RAISR4D

22/08/2026

Neuroinflammation and vaccination strategy in Parkinson’s disease

Adv Immunol. 2026;171:401-435. doi: 10.1016/bs.ai.2026.04.006. Epub 2026 May 12.ABSTRACTParkinson's disease (PD) is a neurodegenerative disorder characterized by loss of dopaminergic neurons in the substantia nigra....

Delirium RAISR4D

22/08/2026

Microglial advances in psychiatric disorders

Adv Immunol. 2026;171:371-400. doi: 10.1016/bs.ai.2026.04.007. Epub 2026 May 15.ABSTRACTPsychiatric disorders constitute a major global challenge to public health, characterized by complex and multifactorial etiologies involving...

Delirium RAISR4D

22/08/2026

Microglial polarisation imbalance and receptor-targeted therapeutics in Parkinson’s disease

Adv Immunol. 2026;171:343-369. doi: 10.1016/bs.ai.2024.10.003. Epub 2026 Apr 22.ABSTRACTParkinson's Disease (PD) is a progressive neurodegenerative disease, which is mainly characterised by the selective depletion of...

Delirium RAISR4D

22/08/2026

Brain macrophages in neurodegeneration

Adv Immunol. 2026;171:33-81. doi: 10.1016/bs.ai.2026.06.005. Epub 2026 Jul 28.ABSTRACTBrain macrophages are not uniform responders to neurodegeneration, but anatomically specialized populations whose functions depend on niche,...

Delirium RAISR4D

22/08/2026

Microglia extracellular traps (MiETs) in Neurodegeneration: Mechanisms, Evidence Gaps, and Untapped Therapeutic Promise

Adv Immunol. 2026;171:307-341. doi: 10.1016/bs.ai.2026.04.008. Epub 2026 Jun 2.ABSTRACTMicroglia are the resident myeloid cells of the central nervous system, they play essential roles in neural...

Delirium RAISR4D

22/08/2026

Microglia in Alzheimer’s disease: Insights into disease progression and therapy

Adv Immunol. 2026;171:283-306. doi: 10.1016/bs.ai.2026.06.004. Epub 2026 Jul 7.ABSTRACTThe role of microglia, once seen as bystanders, has recently shifted to that of central regulators in...

Delirium RAISR4D

22/08/2026

Microglial advances in Parkinson’s disease

Adv Immunol. 2026;171:247-281. doi: 10.1016/bs.ai.2026.06.003. Epub 2026 Jun 22.ABSTRACTMicroglia perform the function of CNS macrophages and act as the primary immune cells in the brain....

Delirium RAISR4D

22/08/2026

Glial control of extracellular α-synuclein propagation in LRRK2 Parkinson’s disease

Adv Immunol. 2026;171:215-246. doi: 10.1016/bs.ai.2026.04.005. Epub 2026 Jun 16.ABSTRACTParkinson's disease (PD) pathology extends well beyond dopaminergic neuronal loss, with glial cells-microglia and astrocytes-emerging as active...

Delirium RAISR4D

21/08/2026

Reverse amblyopia following gene therapy-induced visual improvement in a child with retinal pigment epithelium-65 inherited retinal dystrophy

BMJ Case Rep. 2026 Aug 20;19(8):e273165. doi: 10.1136/bcr-2026-273165.ABSTRACTVoretigene neparvovec can improve visual function in children with RPE65-associated inherited retinal dystrophy. However, the effect of rapid...

Delirium RAISR4D

20/08/2026

Neuroimaging features of white matter lesions related to patent foramen ovale

Zhonghua Yi Xue Za Zhi. 2026 Aug 25;106(31):3285-3290. doi: 10.3760/cma.j.cn112137-20250913-02384.ABSTRACTA retrospective analysis was conducted on the neuroimaging features of white matter lesions related to patent...

Delirium RAISR4D

20/08/2026

Surveillance for Japanese encephalitis in Henan Province, 2004-2025

Zhonghua Liu Xing Bing Xue Za Zhi. 2026 Aug 10;47(8):1457-1463. doi: 10.3760/cma.j.cn112338-20260211-00119.ABSTRACTObjective: To analyze the epidemiological characteristics of Japanese encephalitis (JE) in Henan Province from...

Delirium RAISR4D

20/08/2026

Association of remnant cholesterol with the risk of cardiovascular disease in patients with type 2 diabetes

Zhonghua Liu Xing Bing Xue Za Zhi. 2026 Aug 10;47(8):1432-1439. doi: 10.3760/cma.j.cn112338-20251222-00914.ABSTRACTObjective: To investigate the association between remnant cholesterol (RC) and the incidence of cardiovascular...

Delirium RAISR4D

20/08/2026

Successful Heart and Renal Allograft Transplantation From Patients With Child-Pugh Class C Cirrhosis

Transplant Proc. 2026 Aug 19:S0041-1345(26)00376-3. doi: 10.1016/j.transproceed.2026.06.043. Online ahead of print.ABSTRACTOrgan transplantation is a cornerstone of modern medicine and is often the sole lifesaving option...

Delirium RAISR4D

20/08/2026

Responsibility cannot be abdicated: rigour, proportionate evidence, and full electroencephalography-informed care in perioperative brain health. Response to Br J Anaesth 2026; 137: 269-70

Br J Anaesth. 2026 Aug 19:S0007-0912(26)00544-1. doi: 10.1016/j.bja.2026.06.053. Online ahead of print.NO ABSTRACTPMID:42618367 | DOI:10.1016/j.bja.2026.06.053

Delirium RAISR4D

20/08/2026

Menstruation-triggered paroxysmal hemicrania

BMJ Case Rep. 2026 Aug 19;19(8):e274651. doi: 10.1136/bcr-2026-274651.ABSTRACTA woman in her late 30s presented with a 7-year history of recurrent strictly left-sided headaches occurring exclusively...

Delirium RAISR4D

20/08/2026

Suspected reversible cerebral vasoconstriction syndrome following ethinylestradiol-containing oral contraceptive use in a patient with migraine

BMJ Case Rep. 2026 Aug 19;19(8):e273249. doi: 10.1136/bcr-2026-273249.ABSTRACTOestrogen-containing oral contraceptives (OCPs) are associated with increased cerebrovascular risk, particularly in individuals with migraine and vascular risk...

Delirium RAISR4D

20/08/2026

Four-year evolution of the retinal microvasculature in an APOE ε4/ε4 cognitively normal individual

BMJ Case Rep. 2026 Aug 19;19(8):e274211. doi: 10.1136/bcr-2026-274211.ABSTRACTAlzheimer's disease is a neurodegenerative disorder with a prolonged preclinical phase during which pathological changes begin 15-20 years...

Delirium RAISR4D

20/08/2026

Integrated pathways for acupuncture research from the perspective of systems science: from classical theoretical interpretation to clinical translation

Zhongguo Zhen Jiu. 2026 Aug 12;46(8):1392-1398. doi: 10.13703/j.0255-2930.20250808-0005. Epub 2026 Feb 3.ABSTRACTFrom the perspectives of systems science and translational medicine, this study addresses key issues...

Delirium RAISR4D

20/08/2026

A robust HPLC-HILIC enrichment system for O-glycoproteomics profiling of plasma and cerebrospinal fluid across Alzheimer’s disease progression

Anal Chim Acta. 2026 Oct 15;1419:345899. doi: 10.1016/j.aca.2026.345899. Epub 2026 Jun 26.ABSTRACTBACKGROUND: Alzheimer's disease (AD) pathogenesis involves widespread molecular alterations in both brain tissue and...

Delirium RAISR4D

20/08/2026

Immuno-Metabolic Interactions Along the Microbiota-Gut-Brain Axis in Ischemic Stroke: A Narrative Review

J Stroke Cerebrovasc Dis. 2026 Aug 19:108731. doi: 10.1016/j.jstrokecerebrovasdis.2026.108731. Online ahead of print.ABSTRACTBACKGROUND AND PURPOSE: Ischemic stroke (IS) remains a leading global cause of mortality...

Delirium RAISR4D

20/08/2026

Emotional Stress Induces Spontaneous Scratching Behavior in Mice in the Absence of an Externally Applied Pruritogen

Behav Brain Res. 2026 Aug 19:116440. doi: 10.1016/j.bbr.2026.116440. Online ahead of print.ABSTRACTBACKGROUND: Pruritus is a prevalent condition that significantly impairs quality of life. Although emotional...

Delirium RAISR4D

20/08/2026

Hydrogen sulfide ameliorates cognitive dysfunction in diabetic encephalopathy by activating PI3K/AKT/GSK-3beta signaling to attenuate tau hyperphosphorylation and necroptosis

Exp Neurol. 2026 Aug 19:115987. doi: 10.1016/j.expneurol.2026.115987. Online ahead of print.ABSTRACTDiabetic encephalopathy (DE) is a serious complication of diabetes mellitus characterized by progressive cognitive dysfunction;...

Delirium RAISR4D

20/08/2026

The potential role of GSTO1 in perioperative neurocognitive disorders: a mechanistic hypothesis

Exp Neurol. 2026 Aug 19:115983. doi: 10.1016/j.expneurol.2026.115983. Online ahead of print.ABSTRACTPerioperative neurocognitive disorders (PND) are common and devastating perioperative neurological complications that markedly hinder postoperative...

Delirium RAISR4D

20/08/2026

Salidroside and Tyrosol Exert Anxiolytic Effects by Modulating Brain Endogenous Phenols via 4-Hydroxyphenyllactic Acid as a Key Functional Metabolite

J Ethnopharmacol. 2026 Aug 19:122303. doi: 10.1016/j.jep.2026.122303. Online ahead of print.ABSTRACTETHNOPHARMACOLOGICAL RELEVANCE: Rhodiola crenulata (Hook. f. et Thoms.) H. Ohba is a traditional Tibetan medicine...

Delirium RAISR4D

19/08/2026

Multilingual Evidence-Based Question-Answering for Stroke Discharge Summaries: Study of Cross-Lingual Heterogeneity in Clinical Reports

J Med Internet Res. 2026 Aug 19;28:e96347. doi: 10.2196/96347.ABSTRACTBACKGROUND: The Registry of Stroke Care Quality (RES-Q) is a health care quality improvement platform used globally....

Delirium RAISR4D

19/08/2026

Assessing Treatment Response in Patients With IBS-C in Clinical Practice: Consensus Expert Recommendations Using a Modified Delphi Process

Clin Transl Gastroenterol. 2026 Aug 19. doi: 10.14309/ctg.0000000000001086. Online ahead of print.ABSTRACTINTRODUCTION: Irritable bowel syndrome with constipation (IBS-C) is a common disorder of gut-brain interaction,...

Delirium RAISR4D

19/08/2026

Brainstem glioblastoma in a neurofibromatosis type 1 patient: A rare but aggressive presentation

J Cancer Res Ther. 2026 Apr 1;22(3):594-598. doi: 10.4103/jcrt.jcrt_716_25. Epub 2026 Aug 14.ABSTRACTGlioblastoma multiforme is a highly aggressive central nervous system tumor, rarely seen in...

Delirium RAISR4D

19/08/2026

Pineoblastoma in a 5-Year-Old Male: A Case Report and Review of Literature

Niger Postgrad Med J. 2026 Sep 1;33(5):683-686. doi: 10.4103/npmj.npmj_635_25. Epub 2026 Aug 17.ABSTRACTPineoblastoma (PB) is a rare malignant embryonal tumour arising from the pineal gland....

Delirium RAISR4D

19/08/2026

SKI is critical to counter TGF-β signaling to promote T cell function and autoimmunity

Sci Adv. 2026 Aug 21;12(34):eaeb7051. doi: 10.1126/sciadv.aeb7051. Epub 2026 Aug 19.ABSTRACTTransforming growth factor-β (TGF-β) is central to suppressing T cell function to maintain tolerance and...

Delirium RAISR4D

19/08/2026

Carboxyl-terminal blockade of sortilin binding enhances progranulin gene therapy in a mouse model of frontotemporal dementia

Sci Transl Med. 2026 Aug 19;18(863):eadr9158. doi: 10.1126/scitranslmed.adr9158. Epub 2026 Aug 19.ABSTRACTFrontotemporal dementia is commonly caused by loss-of-function mutations in the progranulin gene. Potential therapies...

Delirium RAISR4D

19/08/2026

MAPT splicing modulators reduce 4R tau and rescue tauopathy phenotypes in human neurons and in a mouse model

Sci Transl Med. 2026 Aug 19;18(863):eady6759. doi: 10.1126/scitranslmed.ady6759. Epub 2026 Aug 19.ABSTRACTTauopathies are neurodegenerative diseases characterized by the pathological accumulation of microtubule-associated protein tau (MAPT)...

Delirium RAISR4D

19/08/2026

Neuronal overexpression of Kcnn1 in A53T α-synuclein mice suppresses phospho-serine 129 α-synuclein formation and doubles survival time

Proc Natl Acad Sci U S A. 2026 Aug 25;123(34):e2622262123. doi: 10.1073/pnas.2622262123. Epub 2026 Aug 19.ABSTRACTSynucleinopathies, including idiopathic Parkinson's Disease, are driven by misfolding and...

Delirium RAISR4D

19/08/2026

When muscles matter in SORD neuropathy

J Neuropathol Exp Neurol. 2026 Aug 19:nlag057. doi: 10.1093/jnen/nlag057. Online ahead of print.ABSTRACTBiallelic pathogenic variants in SORD (Sorbitoldehydrongenase gene), encoding sorbitol dehydrogenase, are a common...

Delirium RAISR4D

19/08/2026

The role of mitochondrial dysfunction and genetics in female infertility and premature ovarian insufficiency

Hum Reprod Update. 2026 Aug 19:dmag022. doi: 10.1093/humupd/dmag022. Online ahead of print.ABSTRACTBACKGROUND: Female infertility occurs in ∼37% of infertile couples, while premature ovarian insufficiency (POI)...

Delirium RAISR4D

19/08/2026

Multicenter External Validation of an AI-Based Funduscopic Carotid Atherosclerosis Score and Assessment of Its Association With Coronary Artery Calcification: External Validation Study

JMIR Med Inform. 2026 Aug 19;14:e77335. doi: 10.2196/77335.ABSTRACTBACKGROUND: Screening for atherosclerosis is essential for early intervention, but conventional screening methods are often invasive and resource-intensive....

Delirium RAISR4D

19/08/2026

Targeting Mutant Phenylalanine Hydroxylase With Pyrimidine-Triazole Conjugates: A Primary Framework for Candidate Chaperone-Based Strategies in Phenylketonuria

FASEB J. 2026 Aug 31;40(16):e72135. doi: 10.1096/fj.202600321R.ABSTRACTPhenylketonuria (PKU) is a rare metabolic disorder caused by pathogenic mutations in the phenylalanine hydroxylase (PAH) gene, which impair...

Delirium RAISR4D

19/08/2026

Ferroptosis and NMDA Receptor Activity in Alzheimer’s Disease: Implications for Amyloid Pathology and P-Glycoprotein Regulation

Drug Dev Res. 2026 Sep;87(6):e70367. doi: 10.1002/ddr.70367.ABSTRACTAlzheimer's disease (AD) is a multifactorial neurodegenerative disorder characterized by progressive cognitive decline, amyloid-β (Aβ) accumulation, oxidative stress, and...

Delirium RAISR4D

19/08/2026

Ginsenoside Rg1 Attenuates Neuroinflammation in Parkinson’s Disease Models via Concomitant Modulation of Canonical and Noncanonical Wnt Pathways in Microglial M1/M2 Polarization

J Agric Food Chem. 2026 Aug 19;74(32):25252-25271. doi: 10.1021/acs.jafc.6c04447.ABSTRACTMicroglial-mediated neuroinflammation is a core driver of brain disorders. Thus, modulating microglial activity is a critical therapeutic...

Delirium RAISR4D

18/08/2026

Beyond the protocol: navigating ethics and governance in the multicentre implementation trials – the QASC Australasia and T3 Trials

Aust Health Rev. 2026 Sep 3;50(3):AH26079. doi: 10.1071/AH26079.ABSTRACTOBJECTIVE: To describe and compare ethics and governance approval timelines for the Quality in Acute Stroke Care (QASC)...

Delirium RAISR4D

18/08/2026

Berberine attenuates necrotizing enterocolitis-associated brain injury via the TLR4/MyD88/NF-kappaB/NLRP3 pathway

Zhongguo Dang Dai Er Ke Za Zhi. 2026 Aug 15;28(8):1008-1018. doi: 10.7499/j.issn.1008-8830.2603057.ABSTRACTOBJECTIVES: To investigate the protective effects and underlying mechanisms of berberine (BBR) on brain...

Delirium RAISR4D

18/08/2026

Clinical features and prognosis of influenza-associated encephalopathy in children

Zhongguo Dang Dai Er Ke Za Zhi. 2026 Aug 15;28(8):984-990. doi: 10.7499/j.issn.1008-8830.2601200.ABSTRACTOBJECTIVES: To investigate the clinical features, prognosis, and factors associated with influenza-associated encephalopathy (IAE)...

Delirium RAISR4D

18/08/2026

Frailty Assessment in Coronary Artery Bypass Grafting: A Review of Current Tools and Clinical Applications

J Cardiothorac Vasc Anesth. 2026 Jul 22:S1053-0770(26)00626-9. doi: 10.1053/j.jvca.2026.07.043. Online ahead of print.ABSTRACTFrailty has emerged as a critical determinant of operative risk among patients undergoing...

Delirium RAISR4D

18/08/2026

Neuropathological Findings Following Failure of Laser Interstitial Thermal Therapy for an Epileptogenic Cerebral Cavernous Malformation

Neuropathol Appl Neurobiol. 2026 Aug;52(4):e70099. doi: 10.1111/nan.70099.ABSTRACTWe describe the case of a 32-year-old woman with focal drug-resistant epilepsy, who underwent surgical resection of a cerebral...

Delirium RAISR4D

18/08/2026

Cardiometabolic factors and risk of dementia in people with type 2 diabetes in England: a large retrospective cohort study

BMJ Open Diabetes Res Care. 2026 Aug 17;14(4):e005743. doi: 10.1136/bmjdrc-2025-005743.ABSTRACTINTRODUCTION: People with type 2 diabetes (T2D) have a higher dementia risk. Cardiometabolic factors may influence...

Delirium RAISR4D

18/08/2026

Understanding the Current UK HEMS Provision for Patients Presenting With Nontraumatic Brain Pathology (NTBP)

Air Med J. 2026 Sep-Oct;45(5):445-448. doi: 10.1016/j.amj.2026.05.007. Epub 2026 Jun 17.ABSTRACTOBJECTIVE: UK helicopter emergency medical services (HEMS) are often tasked to nontraumatic brain pathology (NTBP)...

Delirium RAISR4D

18/08/2026

Effectiveness of nursing interventions for patients with post stroke psychological disorders: A systematic review and meta-analysis

Arch Psychiatr Nurs. 2026 Aug;63:152143. doi: 10.1016/j.apnu.2026.152143. Epub 2026 May 20.ABSTRACTBACKGROUND: Post-stroke psychological disorders impede rehabilitation and long-term wellbeing. Nurses are positioned across the care...

Delirium RAISR4D

18/08/2026

Possible adult-onset hypophosphatasia variant presenting as young-onset parkinsonism with limited levodopa responsiveness

BMJ Case Rep. 2026 Aug 17;19(8):e271629. doi: 10.1136/bcr-2025-271629.ABSTRACTA woman in her late 40s presented with a 1 year history of progressive symmetrical rest tremor, bradykinesia,...

Delirium RAISR4D

18/08/2026

Diagnostic challenges in an atypical presentation of Lyme neuroborreliosis

BMJ Case Rep. 2026 Aug 17;19(8):e270816. doi: 10.1136/bcr-2025-270816.ABSTRACTA man in his early 70s presented with back pain, sleep disturbances, ataxia and confusion, which was initially...

Delirium RAISR4D

18/08/2026

Benign but not harmless: cerebral lymphangioma-related cortical shift causing progressing isolated upper extremity paresis

BMJ Case Rep. 2026 Aug 17;19(8):e269195. doi: 10.1136/bcr-2025-269195.ABSTRACTLymphangiomas (LMs) are rare, benign congenital malformations that can occur in any part of the body but most...

Delirium RAISR4D

18/08/2026

Mapping the longitudinal trajectories of postural control and functional activity after stroke using clinical and sensor-based assessments: protocol of the FOSTER prospective cohort study

BMJ Open. 2026 Aug 17;16(8):e121574. doi: 10.1136/bmjopen-2026-121574.ABSTRACTINTRODUCTION: Stroke is a leading cause of long-term disability, yet recovery trajectories are highly heterogeneous and difficult to predict...

Delirium RAISR4D

18/08/2026

Pathological α-synuclein propagation via the gut-liver axis induces liver injury in gut-origin Parkinson’s disease mouse models

Exp Neurol. 2026 Aug 17:115965. doi: 10.1016/j.expneurol.2026.115965. Online ahead of print.ABSTRACTParkinson's disease (PD) pathogenesis involves α-synuclein (α-syn) aggregation in substantia nigra. The "gut-origin hypothesis" proposes...

Delirium RAISR4D

18/08/2026

The role of the gut-brain axis and polyphenolic compounds in glioblastoma

J Nutr Biochem. 2026 Aug 17:110484. doi: 10.1016/j.jnutbio.2026.110484. Online ahead of print.ABSTRACTPolyphenols are metabolites derived from plant-based sources studied in cancer research for their anti-inflammatory,...

Delirium RAISR4D

18/08/2026

The Gabriella Miller Kids First Data Resource for genomic research in pediatric cancer and congenital anomalies

Am J Hum Genet. 2026 Aug 17:S0002-9297(26)00276-4. doi: 10.1016/j.ajhg.2026.07.010. Online ahead of print.ABSTRACTNine-year-old brain tumor patient Gabriella Miller challenged members of Congress to "stop talking...

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