Delirium – Page 2 – Psychiatry AI: Real-Time AI Scoping Review

Delirium RAISR4D

18/08/2026

Beyond the protocol: navigating ethics and governance in the multicentre implementation trials – the QASC Australasia and T3 Trials

Aust Health Rev. 2026 Sep 3;50(3):AH26079. doi: 10.1071/AH26079.ABSTRACTOBJECTIVE: To describe and compare ethics and governance approval timelines for the Quality in Acute Stroke Care (QASC)...

Delirium RAISR4D

18/08/2026

Berberine attenuates necrotizing enterocolitis-associated brain injury via the TLR4/MyD88/NF-kappaB/NLRP3 pathway

Zhongguo Dang Dai Er Ke Za Zhi. 2026 Aug 15;28(8):1008-1018. doi: 10.7499/j.issn.1008-8830.2603057.ABSTRACTOBJECTIVES: To investigate the protective effects and underlying mechanisms of berberine (BBR) on brain...

Delirium RAISR4D

18/08/2026

Clinical features and prognosis of influenza-associated encephalopathy in children

Zhongguo Dang Dai Er Ke Za Zhi. 2026 Aug 15;28(8):984-990. doi: 10.7499/j.issn.1008-8830.2601200.ABSTRACTOBJECTIVES: To investigate the clinical features, prognosis, and factors associated with influenza-associated encephalopathy (IAE)...

Delirium RAISR4D

18/08/2026

Frailty Assessment in Coronary Artery Bypass Grafting: A Review of Current Tools and Clinical Applications

J Cardiothorac Vasc Anesth. 2026 Jul 22:S1053-0770(26)00626-9. doi: 10.1053/j.jvca.2026.07.043. Online ahead of print.ABSTRACTFrailty has emerged as a critical determinant of operative risk among patients undergoing...

Delirium RAISR4D

18/08/2026

Neuropathological Findings Following Failure of Laser Interstitial Thermal Therapy for an Epileptogenic Cerebral Cavernous Malformation

Neuropathol Appl Neurobiol. 2026 Aug;52(4):e70099. doi: 10.1111/nan.70099.ABSTRACTWe describe the case of a 32-year-old woman with focal drug-resistant epilepsy, who underwent surgical resection of a cerebral...

Delirium RAISR4D

18/08/2026

Cardiometabolic factors and risk of dementia in people with type 2 diabetes in England: a large retrospective cohort study

BMJ Open Diabetes Res Care. 2026 Aug 17;14(4):e005743. doi: 10.1136/bmjdrc-2025-005743.ABSTRACTINTRODUCTION: People with type 2 diabetes (T2D) have a higher dementia risk. Cardiometabolic factors may influence...

Delirium RAISR4D

18/08/2026

Understanding the Current UK HEMS Provision for Patients Presenting With Nontraumatic Brain Pathology (NTBP)

Air Med J. 2026 Sep-Oct;45(5):445-448. doi: 10.1016/j.amj.2026.05.007. Epub 2026 Jun 17.ABSTRACTOBJECTIVE: UK helicopter emergency medical services (HEMS) are often tasked to nontraumatic brain pathology (NTBP)...

Delirium RAISR4D

18/08/2026

Effectiveness of nursing interventions for patients with post stroke psychological disorders: A systematic review and meta-analysis

Arch Psychiatr Nurs. 2026 Aug;63:152143. doi: 10.1016/j.apnu.2026.152143. Epub 2026 May 20.ABSTRACTBACKGROUND: Post-stroke psychological disorders impede rehabilitation and long-term wellbeing. Nurses are positioned across the care...

Delirium RAISR4D

18/08/2026

Possible adult-onset hypophosphatasia variant presenting as young-onset parkinsonism with limited levodopa responsiveness

BMJ Case Rep. 2026 Aug 17;19(8):e271629. doi: 10.1136/bcr-2025-271629.ABSTRACTA woman in her late 40s presented with a 1 year history of progressive symmetrical rest tremor, bradykinesia,...

Delirium RAISR4D

18/08/2026

Diagnostic challenges in an atypical presentation of Lyme neuroborreliosis

BMJ Case Rep. 2026 Aug 17;19(8):e270816. doi: 10.1136/bcr-2025-270816.ABSTRACTA man in his early 70s presented with back pain, sleep disturbances, ataxia and confusion, which was initially...

Delirium RAISR4D

18/08/2026

Benign but not harmless: cerebral lymphangioma-related cortical shift causing progressing isolated upper extremity paresis

BMJ Case Rep. 2026 Aug 17;19(8):e269195. doi: 10.1136/bcr-2025-269195.ABSTRACTLymphangiomas (LMs) are rare, benign congenital malformations that can occur in any part of the body but most...

Delirium RAISR4D

18/08/2026

Mapping the longitudinal trajectories of postural control and functional activity after stroke using clinical and sensor-based assessments: protocol of the FOSTER prospective cohort study

BMJ Open. 2026 Aug 17;16(8):e121574. doi: 10.1136/bmjopen-2026-121574.ABSTRACTINTRODUCTION: Stroke is a leading cause of long-term disability, yet recovery trajectories are highly heterogeneous and difficult to predict...

Delirium RAISR4D

18/08/2026

Pathological α-synuclein propagation via the gut-liver axis induces liver injury in gut-origin Parkinson’s disease mouse models

Exp Neurol. 2026 Aug 17:115965. doi: 10.1016/j.expneurol.2026.115965. Online ahead of print.ABSTRACTParkinson's disease (PD) pathogenesis involves α-synuclein (α-syn) aggregation in substantia nigra. The "gut-origin hypothesis" proposes...

Delirium RAISR4D

18/08/2026

The role of the gut-brain axis and polyphenolic compounds in glioblastoma

J Nutr Biochem. 2026 Aug 17:110484. doi: 10.1016/j.jnutbio.2026.110484. Online ahead of print.ABSTRACTPolyphenols are metabolites derived from plant-based sources studied in cancer research for their anti-inflammatory,...

Delirium RAISR4D

18/08/2026

The Gabriella Miller Kids First Data Resource for genomic research in pediatric cancer and congenital anomalies

Am J Hum Genet. 2026 Aug 17:S0002-9297(26)00276-4. doi: 10.1016/j.ajhg.2026.07.010. Online ahead of print.ABSTRACTNine-year-old brain tumor patient Gabriella Miller challenged members of Congress to "stop talking...

Delirium RAISR4D

17/08/2026

Acid-Base and Electrolyte Disorders: Sodium Disorders

FP Essent. 2026 Jun;565:7-13.ABSTRACTSodium disorders are commonly encountered in clinical practice and are frequently misunderstood. Abnormal serum sodium levels are due to an imbalance in...

Delirium RAISR4D

17/08/2026

Hepatitis Overview: Less Common Causes of Hepatitis

FP Essent. 2026 Jul;566:37-46.ABSTRACTAlthough metabolic, viral, and drug- and alcohol-related etiologies are a familiar part of the evaluation of elevated liver enzymes, less common causes...

Delirium RAISR4D

17/08/2026

Porcine coronavirus promotes NLRP3 inflammasome activation during virus-induced neuroinflammation

mBio. 2026 Aug 17:e0172526. doi: 10.1128/mbio.01725-26. Online ahead of print.ABSTRACTNeurotropic coronaviruses can invade the central nervous system (CNS) and cause severe neurological disease, but the...

Delirium RAISR4D

17/08/2026

Association of low sleep efficiency and carotid plaque with cognitive impairment in older adults with chronic diseases: A retrospective cross-sectional study

J Int Med Res. 2026 Aug;54(8):3000605261476845. doi: 10.1177/03000605261476845. Epub 2026 Aug 17.ABSTRACTObjectiveThis retrospective cross-sectional study aimed to investigate the independent and joint associations of low...

Delirium RAISR4D

17/08/2026

Clinical EEG In Modern Psychiatry: Diagnostics and Prediction

Clin EEG Neurosci. 2026 Aug 17:15500594261471242. doi: 10.1177/15500594261471242. Online ahead of print.ABSTRACTClinical electroencephalography (EEG) remains a central diagnostic tool in psychiatry. As a non-invasive, widely...

Delirium RAISR4D

17/08/2026

Early nurse-detected delirium is a marker of 6-month mortality risk after acute coronary syndrome: A Multicentre Prospective Cohort Study

Eur J Cardiovasc Nurs. 2026 Aug 17:zvag191. doi: 10.1093/eurjcn/zvag191. Online ahead of print.NO ABSTRACTPMID:42606165 | DOI:10.1093/eurjcn/zvag191

Delirium RAISR4D

17/08/2026

Integrated Analysis of Glycolytic and Cholesterogenic Genes Identifies Prognostic Metabolic Subgroup of IDH Wild-Type Glioblastoma

Cancer Med. 2026 Aug;15(8):e72105. doi: 10.1002/cam4.72105.ABSTRACTGlioblastoma (GBM) is a markedly heterogeneous intracranial tumor characterized by poor prognosis. While distinctive glycolysis and cholesterol synthesis capacities exist...

Delirium RAISR4D

17/08/2026

Transferrin-Conjugated Polymeric Nanoparticles via Polymerization-Induced Self-Assembly for Enhanced BBB Transport and Glioblastoma Therapy

ACS Appl Bio Mater. 2026 Aug 17;9(16):7616-7628. doi: 10.1021/acsabm.6c01007.ABSTRACTTransferrin-coated nanoparticles show promise in delivering chemotherapeutic drugs across biological barriers for treating glioblastoma multiforme (GBM). Employing...

Delirium RAISR4D

17/08/2026

Clioquinol-Loaded UiO-66(Ce) Metal-Organic Frameworks for Dual Reactive Oxygen Species Scavenging and Metal Chelation in Alzheimer’s Disease

ACS Appl Bio Mater. 2026 Aug 17;9(16):7629-7636. doi: 10.1021/acsabm.6c01023.ABSTRACTAlzheimer's disease (AD) is a major neurodegenerative disorder associated with amyloid-β (Aβ) aggregation and oxidative stress, often...

Delirium RAISR4D

16/08/2026

Global, Regional, and National Burden of Stroke Attributable to High Systolic Blood Pressure in Adults Aged 45 Years and Above From 1990 to 2021, with Projections to 2045: A Systematic and Comprehensive Analysis of the Global Burden of Disease Study 2021

Arch Iran Med. 2026 Feb 1;29(2):98-111. doi: 10.34172/aim.34957. Epub 2026 Feb 1.ABSTRACTINTRODUCTION: Stroke remains a leading cause of death and disability worldwide, with high systolic...

Delirium RAISR4D

16/08/2026

Mortality Trend of Cerebrovascular Disorders: A Cross-sectional Study in Northern Iran (2016-2023)

Arch Iran Med. 2026 Feb 1;29(2):62-68. doi: 10.34172/aim.34939. Epub 2026 Feb 1.ABSTRACTINTRODUCTION: Cerebrovascular disorders (CeVDs) are among the leading causes of death worldwide. This study...

Delirium RAISR4D

16/08/2026

The First Iranian Patient with West Syndrome Due to a RYR3 Gene Variant: A Case Report and Literature Review

Arch Iran Med. 2026 Jan 1;29(1):53-57. doi: 10.34172/aim.35157. Epub 2026 Jan 1.ABSTRACTWest syndrome (WS) is a severe developmental and epileptic encephalopathy of infancy, defined by...

Delirium RAISR4D

16/08/2026

Early Comprehensive Geriatric Assessment in Acute Care: Evidence and Implementation

Cureus. 2026 Jul 16;18(7):e112760. doi: 10.7759/cureus.112760. eCollection 2026 Jul.ABSTRACTThe growing prevalence of frailty among older adults presenting to acute care settings poses significant challenges for...

Delirium RAISR4D

16/08/2026

Adjusted comparison of antegrade cerebral perfusion techniques during prolonged circulatory arrest in surgery for acute type A aortic dissection

JTCVS Open. 2026 Apr 17;32:101817. doi: 10.1016/j.xjon.2026.101817. eCollection 2026 Aug.ABSTRACTOBJECTIVE: To investigate differences in neurologic outcomes between unilateral and bilateral antegrade cerebral perfusion during prolonged...

Delirium RAISR4D

16/08/2026

Long-term outcomes of childhood encephalitis in Australia: burden and predictors from the Australian childhood encephalitis (ACE) prospective multicentre cohort

Lancet Reg Health West Pac. 2026 Aug 8;73:101951. doi: 10.1016/j.lanwpc.2026.101951. eCollection 2026 Aug.ABSTRACTBACKGROUND: Encephalitis is inflammation of the brain parenchyma with heterogenous aetiology and presentation....

Delirium RAISR4D

16/08/2026

Synergistic cell-cycle repression by HDAC/EZH2 co-targeting in H3K27-altered diffuse midline glioma

Mol Ther Oncol. 2026 Jul 24;34(3):201306. doi: 10.1016/j.omton.2026.201306. eCollection 2026 Sep 17.ABSTRACTDiffuse midline glioma (DMG) is an aggressive malignancy driven by the H3K27M oncohistone, leading...

Delirium RAISR4D

16/08/2026

Proteomic analysis of human chronic traumatic encephalopathy brain implicates proteasome and ribosome dysfunction in disease severity

Mol Neurodegener Adv. 2026;2(1):36. doi: 10.1186/s44477-026-00045-w. Epub 2026 Aug 14.ABSTRACTBACKGROUND: Chronic traumatic encephalopathy (CTE) is a neurodegenerative disease that occurs in individuals with repeated head...

Delirium RAISR4D

16/08/2026

Enabling technologies for neural and biofluid interfaces: biocompatible materials with potential for neurodegenerative disease applications

Biomed Eng Lett. 2026 Mar 25;16(4):883-902. doi: 10.1007/s13534-026-00571-2. eCollection 2026 Jul.ABSTRACTAs global populations age, neurodegenerative diseases impose escalating clinical and economic burdens on healthcare systems...

Delirium RAISR4D

14/08/2026

Association of Low Skeletal Muscle Mass and Low Skeletal Muscle Radiodensity With Postoperative Delirium in Patients Undergoing Off-Pump Coronary Artery Bypass Grafting: A Retrospective Cohort Study

J Cardiothorac Vasc Anesth. 2026 Jul 24:S1053-0770(26)00627-0. doi: 10.1053/j.jvca.2026.07.041. Online ahead of print.ABSTRACTOBJECTIVES: To evaluate the correlation between low skeletal muscle index (SMI) and low...

Delirium RAISR4D

14/08/2026

Corrigendum to “OTUD1 promotes the progession of depression through mitochondrial damage by targeting MST1/2” [Brain, Behav., Immun. 137 (2026) 106846]

Brain Behav Immun. 2026 Aug 13:106921. doi: 10.1016/j.bbi.2026.106921. Online ahead of print.NO ABSTRACTPMID:42595596 | DOI:10.1016/j.bbi.2026.106921

Delirium RAISR4D

14/08/2026

Safety and efficacy of Laager left atrial appendage occlusion system in patients with nonvalvular atrial fibrillation: a prospective, multicenter clinical study

Zhonghua Xin Xue Guan Bing Za Zhi. 2026 Aug 24;54(8):967-973. doi: 10.3760/cma.j.cn112148-20260306-00144.ABSTRACTObjective: To investigate the safety and efficacy of the Laager left atrial appendage occlusion...

Delirium RAISR4D

14/08/2026

MRI diagnosis of an isolated encephalopathy

Pract Neurol. 2026 Aug 13:pn-2026-005335. doi: 10.1136/pn-2026-005335. Online ahead of print.NO ABSTRACTPMID:42595460 | DOI:10.1136/pn-2026-005335

Delirium RAISR4D

14/08/2026

Recurrent stroke in eosinophilic granulomatosis with polyangiitis: the need to consider additional mechanisms beyond vasculitis

BMJ Case Rep. 2026 Aug 13;19(8):e273186. doi: 10.1136/bcr-2026-273186.ABSTRACTEosinophilic granulomatosis with polyangiitis (EGPA) is a rare antineutrophil cytoplasmic antibody-associated vasculitis that typically presents with asthma, eosinophilia...

Delirium RAISR4D

14/08/2026

Cross-cultural adaptation and initial evaluation of measurement properties of the Brazilian Portuguese version of the Lower Extremity Motor Function Test (LE-MFT)

Arq Neuropsiquiatr. 2026 Jul;84(7):1-10. doi: 10.1055/s-0046-1827052. Epub 2026 Aug 13.ABSTRACTBACKGROUND: Lower extremity motor function assessments are essential to evaluate mobility and independence in stroke survivors....

Delirium RAISR4D

14/08/2026

Risk factors for drug-resistant epilepsy according to sex: a cohort study conducted in a middle-income country

Arq Neuropsiquiatr. 2026 Jul;84(7):1-9. doi: 10.1055/s-0046-1827051. Epub 2026 Aug 13.ABSTRACTBACKGROUND: Drug-resistant epilepsy (DRE) affects 30% of patients with epilepsy. Although multiple risk factors (RFs) are...

Delirium RAISR4D

14/08/2026

Cost and clinical outcomes of epilepsy surgery in a Brazilian public hospital: a health economic evaluation

Arq Neuropsiquiatr. 2026 Jul;84(7):1-10. doi: 10.1055/s-0046-1827047. Epub 2026 Aug 13.ABSTRACTBACKGROUND: Epilepsy surgery is an established therapy for drug-resistant epilepsy, but it remains underused in Brazil....

Delirium RAISR4D

14/08/2026

Clinical and epidemiological comparison between perimesencephalic and non-perimesencephalic, non-aneurysmal subarachnoid hemorrhage: a single-center cohort study from a referral center in a developing country

Arq Neuropsiquiatr. 2026 Sep;84(9):1-7. doi: 10.1055/s-0046-1827159. Epub 2026 Aug 13.ABSTRACTBACKGROUND: Non-aneurysmal subarachnoid hemorrhage (SAH) represents a heterogeneous entity with implications for management and prognosis. Perimesencephalic...

Delirium RAISR4D

14/08/2026

The emerging role of high-intensity focused ultrasound (HIFU) as a symptomatic treatment for Parkinson’s disease and essential tremor: a narrative review

Arq Neuropsiquiatr. 2026 Aug;84(8):1-13. doi: 10.1055/s-0046-1827056. Epub 2026 Aug 13.ABSTRACTThe high-intensity focused ultrasound (HIFU) technique has become precise, incisionless, and ablative for treating essential tremor...

Delirium RAISR4D

14/08/2026

Decoding TREM2: A microglial receptor governing the fate of myelin

Cell Signal. 2026 Aug 13:112815. doi: 10.1016/j.cellsig.2026.112815. Online ahead of print.ABSTRACTImpaired myelin integrity and defective myelin regeneration represent core pathological features shared by central nervous...

Delirium RAISR4D

14/08/2026

Depolymerization of aquaporin-4 orthogonal array particles via the A25Q mutation does not cause behavioral deficits but confers resilience to chronic unpredictable mild stress

J Affect Disord. 2026 Aug 13:122376. doi: 10.1016/j.jad.2026.122376. Online ahead of print.ABSTRACTAquaporin-4 (AQP4) formed orthogonal array particles (OAPs) is critical for brain water homeostasis and...

Delirium RAISR4D

14/08/2026

Systemic Mitochondrial DNA Kinetics After cDCD Lung Transplantation Do Not Reflect Donor Warm Ischemic Injury: DACMEDAMPs, a Prospective multicenter translational study

Am J Transplant. 2026 Aug 13:S1600-6135(26)02725-5. doi: 10.1016/j.ajt.2026.08.005. Online ahead of print.ABSTRACTControlled donation after circulatory determination of death (cDCD) has markedly expanded the lung donor...

Delirium RAISR4D

14/08/2026

Construction of a Suckling Mouse Model Based on an EV-C96 Clinical Isolate and Its Application in Drug Screening and Vaccine Development

Antiviral Res. 2026 Aug 13:106511. doi: 10.1016/j.antiviral.2026.106511. Online ahead of print.ABSTRACTEnterovirus C96 (EV-C96) is a novel human enterovirus associated with diseases such as hand, foot,...

Delirium RAISR4D

14/08/2026

An Integrated View of the Pedunculopontine Nucleus: Anatomy, Physiology, and Its Multifaceted Role in Parkinson’s Disease Pathogenesis and Neuromodulation Therapy

Neurosci Biobehav Rev. 2026 Aug 13:106913. doi: 10.1016/j.neubiorev.2026.106913. Online ahead of print.ABSTRACTThe pedunculopontine nucleus (PPN) is a heterogeneous cluster within the dorsolateral pontomesencephalic tegmentum, functioning...

Delirium RAISR4D

13/08/2026

BHLHE22 monoallelic and biallelic variants cause a neurodevelopmental disorder with agenesis of the corpus callosum, intellectual disability, abnormal muscle tone and movement abnormalities

J Med Genet. 2026 Aug 12:jmg-2025-111432. doi: 10.1136/jmg-2025-111432. Online ahead of print.ABSTRACTBACKGROUND: BHLHE22 encodes a basic helix-loop-helix transcription factor expressed exclusively in the retina and...

Delirium RAISR4D

13/08/2026

Papiliotrema Laurentii Bloodstream Infection Following Methylprednisolone Pulse Therapy for Respiratory Syncytial Virus-Associated Acute Encephalopathy in a Child

Tohoku J Exp Med. 2026 Aug 13. doi: 10.1620/tjem.2026.J080. Online ahead of print.NO ABSTRACTPMID:42586742 | DOI:10.1620/tjem.2026.J080

Delirium RAISR4D

13/08/2026

Stakeholder perspectives on brain tumour care across rural-urban boundaries: a reflexive thematic analysis

BMJ Open. 2026 Aug 12;16(8):e119505. doi: 10.1136/bmjopen-2026-119505.ABSTRACTOBJECTIVES: To explore stakeholder perspectives on care coordination barriers and facilitators in regionalised neuro-oncology delivery, using brain tumours as...

Delirium RAISR4D

13/08/2026

Endovascular thrombectomy alone versus intravenous thrombolysis plus endovascular thrombectomy on acute basilar artery occlusion (ATTENTION IV): study protocol for a multicentre randomised controlled trial

BMJ Open. 2026 Aug 12;16(8):e116898. doi: 10.1136/bmjopen-2026-116898.ABSTRACTINTRODUCTION: The DEVT and DIRECT-MT trials showed that endovascular thrombectomy (EVT) alone is non-inferior to intravenous thrombolysis (IVT) followed...

Delirium RAISR4D

13/08/2026

Encapsulated faecal microbiota transfer to target immune activation in patients with cirrhosis and ascites (TransImmune): protocol for a randomised, double-blind, Phase IIa, placebo-controlled trial

BMJ Open. 2026 Aug 12;16(8):e119299. doi: 10.1136/bmjopen-2026-119299.ABSTRACTINTRODUCTION: Bacterial translocation and gut dysbiosis are key drivers of systemic immune activation in decompensated cirrhosis, precipitating inflammatory complications...

Delirium RAISR4D

13/08/2026

Does cathodal HD-tDCS-preconditioned iTBS over the contralesional dorsal premotor cortex improve upper limb motor function in patients with severe ischaemic stroke? A study protocol for a single-centre, participant-blinded and outcome assessor-blinded randomised controlled trial

BMJ Open. 2026 Aug 12;16(8):e120996. doi: 10.1136/bmjopen-2026-120996.ABSTRACTINTRODUCTION: The contralesional dorsal premotor cortex (cPMd) is a potential target for motor recovery in severe stroke. However, interindividual...

Delirium RAISR4D

13/08/2026

Developing organisational capacity building for person-centred dementia care in nursing homes: a multiphase co-design study protocol

BMJ Open. 2026 Aug 12;16(8):e123820. doi: 10.1136/bmjopen-2026-123820.ABSTRACTINTRODUCTION: Person-centred dementia care (PCdC) is widely recognised as a core principle of high-quality dementia care and is embedded...

Delirium RAISR4D

13/08/2026

Clinical features of hereditary adrenocortical unresponsiveness to adrenocorticotropin (HAUA) in Japan: from a nationwide questionnaire based survey

Endocr J. 2026 Aug 11. doi: 10.1507/endocrj.EJ26-0099. Online ahead of print.ABSTRACTHereditary adrenocortical unresponsiveness to adrenocorticotropin (HAUA) is a rare congenital disorder characterized by isolated glucocorticoid...

Delirium RAISR4D

13/08/2026

Engineering of pH/GSH-responsive nanoparticles based on a poly-γ-glutamic acid/chitosan core-shell architecture for synergistic chemo/chemodynamic therapy of glioma

Carbohydr Polym. 2026 Oct 1;389:125601. doi: 10.1016/j.carbpol.2026.125601. Epub 2026 Jun 30.ABSTRACTIn this study, we engineered pH/glutathione dual-responsive nanoparticles (LP/CC-Cu-Cur NPs) based on a poly-γ-glutamic acid...

Delirium RAISR4D

13/08/2026

Real-world clinical characteristics of motor disorders for personalised brain-computer interfaces: phenotypic insights from a specialised clinic

Stroke Vasc Neurol. 2026 Aug 12:svn-2026-005290. doi: 10.1136/svn-2026-005290. Online ahead of print.ABSTRACTMotor dysfunction caused by neurological disorders such as stroke, spinal cord injury and amyotrophic...

Delirium RAISR4D

13/08/2026

Pseudo-heart failure in pregnancy complicated by preeclampsia: giant mediastinal teratoma with extrinsic cardiopulmonary compression

BMJ Case Rep. 2026 Aug 12;19(8):e274681. doi: 10.1136/bcr-2026-274681.ABSTRACTA woman in her early 20s at 30 weeks of gestation presented with elevated blood pressure, transaminitis, progressive...

Delirium RAISR4D

13/08/2026

Balamuthia mandrillaris presenting as central nervous system vasculitis in a young child

BMJ Case Rep. 2026 Aug 12;19(8):e275051. doi: 10.1136/bcr-2026-275051.ABSTRACTBalamuthia mandrillaris is a rare and difficult-to-diagnose infection with high mortality. We present the case of an immunocompetent...

Delirium RAISR4D

13/08/2026

Patient experience and stroke care quality: a quality improvement initiative in Northeastern Ontario

BMJ Open Qual. 2026 Aug 12;15(3):e003751. doi: 10.1136/bmjoq-2025-003751.ABSTRACTBACKGROUND: Patient-reported experience measures (PREM) are key indicators of healthcare quality linked to improved outcomes. The Canadian Stroke...

Delirium RAISR4D

12/08/2026

Syphilis infection and incident dementia in two real-world cohorts: A harmonized propensity-matched analysis in Taiwan NHIRD and TriNetX Asia-Pacific

Brain Behav Immun. 2026 Aug 11:106944. doi: 10.1016/j.bbi.2026.106944. Online ahead of print.ABSTRACTBACKGROUND: Syphilis is a treatable infection with established neurotropism and broad systemic inflammatory consequences,...

Delirium RAISR4D

12/08/2026

Syphilis infection and incident dementia in two real-world cohorts: A harmonized propensity-matched analysis in Taiwan NHIRD and TriNetX Asia-Pacific

Brain Behav Immun. 2026 Aug 11:106944. doi: 10.1016/j.bbi.2026.106944. Online ahead of print.ABSTRACTBACKGROUND: Syphilis is a treatable infection with established neurotropism and broad systemic inflammatory consequences,...

Delirium RAISR4D

12/08/2026

Hydroxylated poly(amidoamine) dendrimers mediate the co-delivery of proteins and drugs for enhanced neuroprotection against ischemic stroke

Acta Biomater. 2026 Aug 11:S1742-7061(26)00549-0. doi: 10.1016/j.actbio.2026.08.016. Online ahead of print.ABSTRACTDevelopment of nanomedicines that can cross blood-brain barrier (BBB) for effective multi-target mitigation of ischemic...

Delirium RAISR4D

11/08/2026

Comparative assessment of post-transport disease susceptibility in Asian seabass (Lates calcarifer): Associations with oxidative stress, immune responses, gut microbiota, and tissue pathology

Comp Biochem Physiol Part D Genomics Proteomics. 2026 Jul 31;60:101961. doi: 10.1016/j.cbd.2026.101961. Online ahead of print.ABSTRACTStress is a crucial factor that affects aquaculture systems, particularly...

Delirium RAISR4D

11/08/2026

A glioblastoma mimic: successful multimodal treatment of a rare dual fungal brain abscess in an immunocompetent patient. Illustrative case

J Neurosurg Case Lessons. 2026 Aug 10;12(6):CASE26529. doi: 10.3171/CASE26529. Print 2026 Aug 10.ABSTRACTBACKGROUND: Cerebral phaeohyphomycosis is a rare but often fatal CNS infection caused by...

Delirium RAISR4D

11/08/2026

Herpes simplex virus encephalitis following acute brain injury: illustrative cases

J Neurosurg Case Lessons. 2026 Aug 10;12(6):CASE26525. doi: 10.3171/CASE26525. Print 2026 Aug 10.ABSTRACTBACKGROUND: Herpes simplex virus (HSV) is the most common cause of sporadic viral...

Delirium RAISR4D

11/08/2026

Primary care-based post diagnostic dementia care in England: modelling and scaling up evidence-based models for efficient future care

Age Ageing. 2026 Aug 3;55(8):afag232. doi: 10.1093/ageing/afag232.ABSTRACTBACKGROUND: The global prevalence of dementia is rising rapidly, placing increasing pressure on health and social care systems to...

Delirium RAISR4D

11/08/2026

Network Analysis-Driven Machine Learning Model for Identifying High-Cost Stroke Inpatients Using Hospital Discharge Data: Retrospective Study

JMIR Med Inform. 2026 Aug 10;14:e93680. doi: 10.2196/93680.ABSTRACTBACKGROUND: The medical burden caused by stroke is increasingly severe, and a small minority of high-cost patients consume...

Delirium RAISR4D

11/08/2026

Parkinsonism as a Potential Neurologic Immune-Mediated Adverse Event of Immune Checkpoint Inhibitors

Neurol Neuroimmunol Neuroinflamm. 2026 Sep;13(5):e200644. doi: 10.1212/NXI.0000000000200644. Epub 2026 Aug 10.ABSTRACTOBJECTIVES: Immune checkpoint inhibitor (ICI)-related parkinsonism is an exceedingly rare neurologic immune-related adverse event (irAE).METHODS:...

Delirium RAISR4D

11/08/2026

Comparison of Brain Age With Standard MRI Assessment for Dementia Risk Stratification in Subjective and Mild Cognitive Impairment

Neurology. 2026 Sep 8;107(5):e218418. doi: 10.1212/WNL.0000000000218418. Epub 2026 Aug 10.ABSTRACTBACKGROUND AND OBJECTIVES: Early dementia risk-stratification is crucial for timely intervention. Brain-predicted age difference (brain-PAD) derived...

Delirium RAISR4D

10/08/2026

Vision saved: the first four years of the pediatric ophthalmology screening program of the Hungarian Charity Service of the Order of Malta – Part II.

Orv Hetil. 2026 Aug 9;167(32):1277-1287. doi: 10.1556/650.2026.33591. Print 2026 Aug 9.ABSTRACTINTRODUCTION: Amblyopia is one of the most common causes of preventable permanent visual impairment in...

Delirium RAISR4D

10/08/2026

Ischemic Hepatopathy Without Shock: A Complication of Pancreatitis

Cureus. 2026 Jul 9;18(7):e112343. doi: 10.7759/cureus.112343. eCollection 2026 Jul.ABSTRACTWhile ischemic hepatopathy is most commonly associated with systemic hypotension or cardiac failure, it may also occur...

Delirium RAISR4D

10/08/2026

Investigation of brain connectivity alteration in the non-severe traumatic brain injury: an emotional condition study

PeerJ. 2026 Aug 5;14:e21593. doi: 10.7717/peerj.21593. eCollection 2026.ABSTRACTBACKGROUND: Traumatic brain injury (TBI) frequently results in persistent emotional and cognitive dysfunction, yet the neural mechanisms underlying...

Delirium RAISR4D

10/08/2026

Determination of corneal phase and group refractive indices in situ and dispersion ex vivo using a hybrid spectral-domain OCT and confocal scanning system

J Biomed Opt. 2026 Aug;31(8):086003. doi: 10.1117/1.JBO.31.8.086003. Epub 2026 Aug 8.ABSTRACTSIGNIFICANCE: Precise determination of corneal refractive indices is essential for accurate refractive power calculations, personalized...

Delirium RAISR4D

09/08/2026

Development and external validation of an online interpretable machine-learning model for predicting delirium risk in acute heart failure

J Int Med Res. 2026 Aug;54(8):3000605261472037. doi: 10.1177/03000605261472037. Epub 2026 Aug 8.ABSTRACTObjectiveDelirium is a frequent complication in acute heart failure and is associated with poor...

Delirium RAISR4D

09/08/2026

IL-19(+) monocytes suppress neuroinflammation and promote neurological recovery in young individuals with traumatic brain injury

Cell Rep. 2026 Aug 7;45(8):117805. doi: 10.1016/j.celrep.2026.117805. Online ahead of print.ABSTRACTYoung patients with traumatic brain injury (TBI) have a better prognosis than the aged, but...

Delirium RAISR4D

09/08/2026

APOE3 and APOE4 human astrocytes differentially modulate Alzheimer’s disease pathology and microglial responses in chimeric mice

Cell Rep. 2026 Aug 8;45(8):117803. doi: 10.1016/j.celrep.2026.117803. Online ahead of print.ABSTRACTAstrocytes and APOE are strongly implicated in Alzheimer's disease (AD), yet the impact of astrocytes...

Delirium RAISR4D

09/08/2026

Clinical Spectrum, Clinical Associations, and Treatment Outcomes of Scedosporiosis in South India: A Retrospective Cohort Study

Med Mycol. 2026 Aug 8:myag074. doi: 10.1093/mmy/myag074. Online ahead of print.ABSTRACTScedosporium is an emerging opportunistic filamentous fungus widely distributed in soil and stagnant water. Mortality...

Delirium RAISR4D

09/08/2026

Treatment of Acute Ischemic Stroke with Intravenous Urokinase (TASK-UK): Protocol for a Multicenter, Prospective, Real-World Study

Neurol Ther. 2026 Aug 8. doi: 10.1007/s40120-026-01006-x. Online ahead of print.ABSTRACTBACKGROUND: Intravenous thrombolysis with recombinant tissue plasminogen activator (rt-PA) and urokinase (UK) are both recommended...

Delirium RAISR4D

09/08/2026

Frailty before disease onset: risk of mortality and chronic conditions in disease-free middle-aged adults

Geroscience. 2026 Aug 8. doi: 10.1007/s11357-026-02459-6. Online ahead of print.ABSTRACTFrailty, defined by multisystem physiological decline and heightened vulnerability to stressors, is typically associated with aging...

Delirium RAISR4D

09/08/2026

CCDC50 Alleviates Cerebral Ischemia-Reperfusion Injury via Enhancing Autophagy to Inhibit STING/IRF3-Mediated Microglial Polarization

Mol Neurobiol. 2026 Aug 8;63(1):823. doi: 10.1007/s12035-026-06099-x.ABSTRACTIschemia-reperfusion injury (IRI) is a major reason for adverse prognosis in ischemic stroke, with multiple signaling pathways involved in...

Delirium RAISR4D

09/08/2026

Targeting Microglial C5aR1 with PMX205 Attenuates Neuroinflammation and Improves Neurological Recovery After Intracerebral Hemorrhage

Neurochem Res. 2026 Aug 8;51(4):235. doi: 10.1007/s11064-026-04858-9.ABSTRACTActivation of microglia and inflammatory response play a central role in the pathological process following intracerebral hemorrhage (ICH). In...

Delirium RAISR4D

09/08/2026

Serum miR-369-3p Downregulation Correlates with Poor Prognosis in Acute Ischemic Stroke and Mitigates Endothelial Injury by Targeting VAV3

Neurochem Res. 2026 Aug 8;51(4):233. doi: 10.1007/s11064-026-04852-1.ABSTRACTGlobally, acute ischemic stroke (AIS) continues to be a major contributor to death and long-term functional impairment. The present...

Delirium RAISR4D

09/08/2026

Actin, connexin-43 and GAP-43 expression in gliomas: real-world associations with IDH status, tumor burden and survival

J Neurooncol. 2026 Aug 8;179(1):36. doi: 10.1007/s11060-026-05745-7.ABSTRACTBACKGROUND: Connexin-43 (Cx43), GAP-43 and actin are involved in cellular communication and cytoskeletal dynamics in gliomas, yet their clinical...

Delirium RAISR4D

08/08/2026

Complications of Midazolam in the Management of Agitated Patients in the Emergency Department: A Dutch Observational Study

J Emerg Med. 2026 Jul 9;88:134-143. doi: 10.1016/j.jemermed.2026.07.005. Online ahead of print.ABSTRACTBACKGROUND: Hyperactive delirium with agitation is a medical emergency requiring rapid pharmacological treatment. Midazolam...

Delirium RAISR4D

08/08/2026

Exploring barriers and facilitators to the implementation of non-pharmacological preventive nursing interventions for postoperative delirium in elderly adults with hip fracture based on the consolidated framework for implementation research: A qualitative study

Int J Orthop Trauma Nurs. 2026 Jul 31;62:101309. doi: 10.1016/j.ijotn.2026.101309. Online ahead of print.ABSTRACTINTRODUCTION: Non-pharmacological prevention of postoperative delirium in elderly hip fracture patients shortens...

Delirium RAISR4D

08/08/2026

Machine Learning Characterization of Readmissions After Chronic Subdural Hematoma Hospitalizations

Neurology. 2026 Sep 8;107(5):e218438. doi: 10.1212/WNL.0000000000218438. Epub 2026 Aug 7.ABSTRACTBACKGROUND AND OBJECTIVES: Readmission after chronic or subacute subdural hematoma (cSDH/sSDH) hospitalization is common, yet clinical...

Delirium RAISR4D

08/08/2026

Early rehabilitation initiation after aneurysmal subarachnoid haemorrhage: evaluation of mortality and functional outcomes

Eur Stroke J. 2026 Aug 5;11(8):aakag090. doi: 10.1093/esj/aakag090.ABSTRACTINTRODUCTION: Evidence regarding the optimal timing of rehabilitation after aneurysmal subarachnoid haemorrhage (aSAH) remains limited. In this study,...

Delirium RAISR4D

08/08/2026

Effect of anaesthesia modality on outcome in medium or distal vessel occlusion stroke: a post-hoc analysis of the DISTAL trial

Eur Stroke J. 2026 Aug 5;11(8):aakag088. doi: 10.1093/esj/aakag088.ABSTRACTINTRODUCTION: Of the 3 published trials, only 1 showed possible efficacy of endovascular treatment (EVT) compared to best...

Delirium RAISR4D

08/08/2026

Secondary prevention of myocardial infarction in people with dementia: a multi-jurisdictional retrospective cohort study in Asia, Europe and the USA

Age Ageing. 2026 Aug 3;55(8):afag220. doi: 10.1093/ageing/afag220.ABSTRACTBACKGROUND: Statins, renin-angiotensin system inhibitors (RASIs) and beta-blockers are guideline-recommended cardiovascular medications post-myocardial infarction (MI) for secondary prevention, but...

Delirium RAISR4D

08/08/2026

Genetic evidence for a causal role of depression in late-onset Alzheimer disease: A Mendelian randomization study

Medicine (Baltimore). 2026 Aug 7;105(32):e50116. doi: 10.1097/MD.0000000000050116.ABSTRACTObservational studies link psychiatric disorders to Alzheimer disease (AD), but whether these associations are causal remains unclear due to...

Delirium RAISR4D

08/08/2026

Causal association between air pollution and functional outcome after ischemic stroke: Evidence from 2-sample MR study

Medicine (Baltimore). 2026 Aug 7;105(32):e50160. doi: 10.1097/MD.0000000000050160.ABSTRACTObservational studies have shown that air pollution may affect functional outcome following ischemic stroke. Our study aimed to explore...

Delirium RAISR4D

08/08/2026

Trends and disparities in risk factors of ischemic stroke among young and middle-aged adults (20-54 years) globally from 1990 to 2021: A population-based study

Medicine (Baltimore). 2026 Aug 7;105(32):e50104. doi: 10.1097/MD.0000000000050104.ABSTRACTThis study aimed to analyze the global disease burden, temporal trends of ischemic stroke (IS) in adults aged 20...

Delirium RAISR4D

08/08/2026

Risk factors associated with delirium in older emergency department patients: A systematic review and meta-analysis

Medicine (Baltimore). 2026 Aug 7;105(32):e50157. doi: 10.1097/MD.0000000000050157.ABSTRACTBACKGROUND: Delirium is a frequent yet underrecognized neuropsychiatric syndrome among older patients presenting to the emergency department (ED) and...

Delirium RAISR4D

07/08/2026

Dual roles of oral and gut bacterial extracellular vesicles in central nervous system diseases: Pathogenic drivers and therapeutic vectors

Microbiol Res. 2026 Aug 4;312:128661. doi: 10.1016/j.micres.2026.128661. Online ahead of print.ABSTRACTA growing body of evidence indicates that the oral and gut microbiota are closely linked...

Delirium RAISR4D

07/08/2026

Bedside Intraoral Scanning to Reduce Procedural Burden in Older Adults With Dementia: Nonrandomized Counterbalanced Crossover Feasibility Study

JMIR Form Res. 2026 Aug 6;10:e92879. doi: 10.2196/92879.ABSTRACTBACKGROUND: Older adults living with dementia often have limited tolerance for intraoral procedures, which can restrict access to...

Delirium RAISR4D

07/08/2026

Utility of Tablet-Based Eye Tracking for Early Screening of Poststroke Cognitive Impairment: Diagnostic Cohort Study

JMIR Mhealth Uhealth. 2026 Aug 6;14:e83194. doi: 10.2196/83194.ABSTRACTBACKGROUND: Poststroke cognitive impairment (PSCI) is a common and disabling complication after stroke; however, early screening remains challenging...

Delirium RAISR4D

07/08/2026

Clinical outcomes associated with dynamic changes in serum sodium amongst adult patients with spontaneous subarachnoid hemorrhage and other critical illnesses: an exploratory scoping review

Crit Care Sci. 2026 Aug 3;38:e20260019. doi: 10.62675/2965-2774.20260019. eCollection 2026.ABSTRACTIncident dysnatremia has been reported amongst varied intensive care unit disease populations and is associated with...

Delirium RAISR4D

07/08/2026

Prevalence and impact of orofacial pain in older adults with dementia: a systematic review and meta-analysis

Codas. 2026 Jul 31;38(5):e20250380. doi: 10.1590/2317-1782/e20250380en. eCollection 2026.ABSTRACTPURPOSE: This systematic review and meta-analysis aimed to determine the prevalence and impact of orofacial pain among older...

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