Category: Substance Use Disorders

West J Emerg Med. 2026 Jul 31;27(5):1321-1326. doi: 10.5811/westjem.62063.ABSTRACTINTRODUCTION: Historically, flumazenil was employed as both a diagnostic aid in unresponsive patients and as an antidote...

West J Emerg Med. 2026 Aug 26;27(5):1402-1410. doi: 10.5811/westjem.52947.ABSTRACTINTRODUCTION: Since 2019, transmission risk factors among patients diagnosed with HIV have changed, although the trends and...

West J Emerg Med. 2026 Jul 28;27(5):1374-1383. doi: 10.5811/westjem.53968.ABSTRACTINTRODUCTION: Adolescents frequently seek care in the emergency department (ED) for behavioral health emergencies. Due to national...

West J Emerg Med. 2026 Aug 6;27(5):1393-1401. doi: 10.5811/westjem.47232.ABSTRACTINTRODUCTION: Emergency departments (ED) have become important venues for hepatitis C (HCV) screening. Similarly, EDs have had...

CMAJ. 2026 Oct 18;198(36):E1407. doi: 10.1503/cmaj.260633.NO ABSTRACTPMID:42896881 | DOI:10.1503/cmaj.260633

CMAJ. 2026 Oct 18;198(36):E1427-E1428. doi: 10.1503/cmaj.260399-f.NO ABSTRACTPMID:42896876 | DOI:10.1503/cmaj.260399-f

J Am Acad Child Adolesc Psychiatry. 2026 Oct 19:S0890-8567(26)02195-7. doi: 10.1016/j.jaac.2026.10.012. Online ahead of print.NO ABSTRACTPMID:42896820 | DOI:10.1016/j.jaac.2026.10.012

J Subst Use Addict Treat. 2026 Oct 19:210143. doi: 10.1016/j.josat.2026.210143. Online ahead of print.ABSTRACTINTRODUCTION: The National Drug Abuse Treatment Clinical Trials Network (CTN) is a...

J Subst Use Addict Treat. 2026 Oct 19:210142. doi: 10.1016/j.josat.2026.210142. Online ahead of print.ABSTRACTINTRODUCTION: Opioid use disorder (OUD) during pregnancy poses significant risks for maternal...

Curr Biol. 2026 Oct 19:S0960-9822(26)01266-2. doi: 10.1016/j.cub.2026.09.057. Online ahead of print.ABSTRACTInternal states like hunger, pain, thirst, and arousal can bias behavior by affecting sensory and...

Drug Alcohol Depend. 2026 Oct 13;288:113398. doi: 10.1016/j.drugalcdep.2026.113398. Online ahead of print.ABSTRACTBACKGROUND: Sexual minority adults experience elevated rates of substance use, yet recent national data...

J Emerg Med. 2026 Sep 23;90:183-187. doi: 10.1016/j.jemermed.2026.09.011. Online ahead of print.ABSTRACTBACKGROUND: Emergency Medical Services (EMS) providers are on the frontline of the opioid epidemic...

JMIR Form Res. 2026 Oct 19;10:e100667. doi: 10.2196/100667.ABSTRACTOne in three young adults reported substance-related generative AI use, mainly for seeking information on substances, with higher...

Int J Epidemiol. 2026 Oct 14;55(6):dyag191. doi: 10.1093/ije/dyag191.ABSTRACTBACKGROUND: The present study aimed to estimate the alcohol-attributable mortality in Aotearoa New Zealand (Aotearoa) at varying levels...

J Subst Use Addict Treat. 2026 Oct 18:210141. doi: 10.1016/j.josat.2026.210141. Online ahead of print.ABSTRACTINTRODUCTION: Parental substance use is a common reason families become involved with...

Iran J Basic Med Sci. 2026;29(11):1670-1676. doi: 10.22038/ijbms.2026.95516.20587.ABSTRACTOBJECTIVES: Zolpidem is a non-benzodiazepine GABAA receptor positive modulator commonly used to treat short-term insomnia. Given its widespread...

Front Syst Neurosci. 2026 Oct 1;20:1907416. doi: 10.3389/fnsys.2026.1907416. eCollection 2026.ABSTRACTHeavy episodic drinking (HED) is highly prevalent in men and a major risk factor for Alcohol...

Perspect Sex Reprod Health. 2026 Oct 16. doi: 10.1111/psrh.70097. Online ahead of print.NO ABSTRACTPMID:42888001 | DOI:10.1111/psrh.70097

J Subst Use Addict Treat. 2026 Oct 16:210139. doi: 10.1016/j.josat.2026.210139. Online ahead of print.ABSTRACTINTRODUCTION: The population of individuals involved with the United States criminal legal...

J Affect Disord. 2026 Oct 16:122637. doi: 10.1016/j.jad.2026.122637. Online ahead of print.ABSTRACTBACKGROUND: Suicide is a global public health concern, with the highest rates among older...

J Med Genet. 2026 Oct 14:jmg-2026-111761. doi: 10.1136/jmg-2026-111761. Online ahead of print.NO ABSTRACTPMID:42875165 | DOI:10.1136/jmg-2026-111761

Chin Med Sci J. 2026 Jun;41(2):62-71. doi: 10.1016/j.cmsj.2026.08.002. Epub 2026 Sep 4.ABSTRACTOBJECTIVE: To evaluate the global disease burden and indirect economic costs of neurological, mental,...

J Subst Use Addict Treat. 2026 Oct 14:210138. doi: 10.1016/j.josat.2026.210138. Online ahead of print.ABSTRACTINTRODUCTION: Withdrawal is a common and debilitating experience among people who use...

Physiol Behav. 2026 Oct 14:115538. doi: 10.1016/j.physbeh.2026.115538. Online ahead of print.ABSTRACTMethamphetamine (METH) is a potent stimulant drug that significantly alters the function of the central...

Lancet Psychiatry. 2026 Nov;13(11):931-942. doi: 10.1016/S2215-0366(26)00276-2.ABSTRACTBACKGROUND: Many individuals with schizophrenia have persistent psychotic symptoms despite antipsychotic treatment, and the disorder is associated with a disproportionately...

Lancet Psychiatry. 2026 Nov;13(11):919-930. doi: 10.1016/S2215-0366(26)00275-0.ABSTRACTBACKGROUND: Compulsory mental health care aims to manage risk and treatment needs among people with severe mental illness, but evidence...

Lancet Psychiatry. 2026 Nov;13(11):906-907. doi: 10.1016/S2215-0366(26)00300-7.NO ABSTRACTPMID:42874599 | DOI:10.1016/S2215-0366(26)00300-7

Psychiatr Prax. 2026 Oct 14. doi: 10.1055/a-2967-3589. Online ahead of print.ABSTRACTOBJECTIVE: Differences between patients with and without previous psychotic symptoms (PPS) in forensic addiction treatment...

Burns. 2026 Oct 9;52(9):108253. doi: 10.1016/j.burns.2026.108253. Online ahead of print.ABSTRACTSingle nucleotide variants in the CYP2C19 gene, as well as some non-genetic factors, are associated with...

Gen Hosp Psychiatry. 2026 Oct 3;103:173-180. doi: 10.1016/j.genhosppsych.2026.09.017. Online ahead of print.ABSTRACTOBJECTIVE: Gambling disorder is associated with suicide and other severe harms. In an era...

Addict Behav. 2026 Oct 8;185:108877. doi: 10.1016/j.addbeh.2026.108877. Online ahead of print.ABSTRACTThe present study aimed to address conceptual and measurement challenges in assessing problematic social media...

Nat Commun. 2026 Sep 10;17(1):10676. doi: 10.1038/s41467-026-77594-x.ABSTRACTThe growing number of patients susceptible to invasive Candida albicans infections has intensified the need for effective antifungal targets...

J Addict Med. 2026 Oct 9. doi: 10.1097/ADM.0000000000001789. Online ahead of print.ABSTRACTOBJECTIVES: Medetomidine, a veterinary alpha-2-adrenergic agonist, has emerged as a dominant adulterant in the...

J Sch Health. 2026 Oct;96(10):e70261. doi: 10.1111/josh.70261.ABSTRACTBACKGROUND: Identifying early substance use and at-risk adolescents is a challenge for public health. The objective was to identify...

Subst Abuse Rehabil. 2026 Oct 6;17:632303. doi: 10.2147/SAR.S632303. eCollection 2026.ABSTRACTINTRODUCTION: mHealth interventions have demonstrated positive outcomes across various health domains and represent promising tools for...

Brain Behav Immun Health. 2026 Sep 21;57:101372. doi: 10.1016/j.bbih.2026.101372. eCollection 2026 Nov.ABSTRACTBACKGROUND: Antenatal depression is a major public health concern, yet the factors distinguishing clinically...

Tob Control. 2026 Oct 9:tc-2026-060210. doi: 10.1136/tc-2026-060210. Online ahead of print.NO ABSTRACTPMID:42855301 | DOI:10.1136/tc-2026-060210

BMJ Open. 2026 Oct 9;16(10):e122747. doi: 10.1136/bmjopen-2026-122747.NO ABSTRACTPMID:42855248 | DOI:10.1136/bmjopen-2026-122747

BMJ Open. 2026 Oct 9;16(10):e121183. doi: 10.1136/bmjopen-2026-121183.NO ABSTRACTPMID:42855240 | DOI:10.1136/bmjopen-2026-121183

JMIR Form Res. 2026 Oct 9;10:e102905. doi: 10.2196/102905.ABSTRACTBACKGROUND: Children of parents with mental health illness (COPMI) have the right to receive preventive interventions to avoid...

Prog Neuropsychopharmacol Biol Psychiatry. 2026 Oct 9:111971. doi: 10.1016/j.pnpbp.2026.111971. Online ahead of print.ABSTRACTFentanyl is a potent synthetic opioid with high misuse potential and risk for...

J Control Release. 2026 Oct 9:115453. doi: 10.1016/j.jconrel.2026.115453. Online ahead of print.ABSTRACTRetinoblastoma is a rare pediatric intraocular malignancy for which intravitreal administration offers a clinically...

Biochim Biophys Acta Rev Cancer. 2026 Oct 9:189732. doi: 10.1016/j.bbcan.2026.189732. Online ahead of print.ABSTRACTSmall interfering RNA (siRNA) has achieved clinical success in liver-directed therapies, but...

J Affect Disord. 2026 Oct 9:122607. doi: 10.1016/j.jad.2026.122607. Online ahead of print.ABSTRACTThe cooccurrence of internalizing and substance use disorders can be explained from several perspectives,...

J Affect Disord. 2026 Oct 9:122611. doi: 10.1016/j.jad.2026.122611. Online ahead of print.ABSTRACTAlexithymia, as a deficit in emotional processing, may be associated with increased vulnerability to...

Psychiatry Res. 2026 Oct 6;367:117492. doi: 10.1016/j.psychres.2026.117492. Online ahead of print.ABSTRACTThis systematic review and pairwise meta-analysis examined the efficacy of psychological and psychosocial smoking cessation...

Schizophr Res. 2026 Oct 9;298:88-95. doi: 10.1016/j.schres.2026.09.046. Online ahead of print.ABSTRACTTobacco and cannabis use are highly prevalent among individuals with psychotic disorders. Tobacco use has...

Schizophr Res. 2026 Oct 9;298:104-116. doi: 10.1016/j.schres.2026.09.044. Online ahead of print.ABSTRACTBACKGROUND: Although 40%-60% of patients with schizophrenia achieve symptomatic remission, residual symptoms often persist. Negative...

J Pediatr Nurs. 2026 Oct 8:S0882-5963(26)00505-1. doi: 10.1016/j.pedn.2026.09.054. Online ahead of print.NO ABSTRACTPMID:42850133 | DOI:10.1016/j.pedn.2026.09.054

AIDS Patient Care STDS. 2026 Oct 8:10872914261494329. doi: 10.1177/10872914261494329. Online ahead of print.ABSTRACTLong-acting injectable cabotegravir (CAB-LA) may be particularly advantageous for preventing HIV among people...

Addiction. 2026 Oct 8. doi: 10.1111/add.70618. Online ahead of print.ABSTRACTBACKGROUND AND AIMS: Cigarette smoking is detrimental to oral health. Oral health professionals rarely prescribe smoking...

Australas Psychiatry. 2026 Oct 7:10398562261492164. doi: 10.1177/10398562261492164. Online ahead of print.ABSTRACTPrivate psychiatric hospitals provide access to care for the approximately 46% of Australians who pay...

J Med Internet Res. 2026 Oct 7;28:e97131. doi: 10.2196/97131.ABSTRACTLarge language model (LLM)-based systems have tremendous potential to improve patient-centered health care, especially for medically underserved...

J Int Med Res. 2026 Oct;54(10):3000605261490827. doi: 10.1177/03000605261490827. Epub 2026 Oct 7.ABSTRACTObjectiveAlcoholic liver disease is a major cause of liver-related mortality, accounting for approximately half...

Cannabis Cannabinoid Res. 2026 Oct 7:25785125261493191. doi: 10.1177/25785125261493191. Online ahead of print.ABSTRACTINTRODUCTION: Use of cannabinoid vape products during pregnancy is a major public health concern....

J Dermatol. 2026 Oct 6. doi: 10.1111/1346-8138.70523. Online ahead of print.ABSTRACTAtopic dermatitis (AD) is a chronic inflammatory skin disease characterized by persistent itch and a...

J Am Board Fam Med. 2026 Oct;39(1):171686. doi: 10.3122/jabfm.2025.250419R2.ABSTRACTTelemedicine for opioid use disorder (teleOUD) represents a critical opportunity to expand access to evidence-based treatment while...

Addiction. 2026 Oct 6. doi: 10.1111/add.70635. Online ahead of print.NO ABSTRACTPMID:42838733 | DOI:10.1111/add.70635

Addiction. 2026 Oct 4. doi: 10.1111/add.70617. Online ahead of print.ABSTRACTBACKGROUND AND AIM: Nicotine pouches are novel products with rapid global sales growth. Our aim was...

J Subst Use Addict Treat. 2026 Oct 3:210128. doi: 10.1016/j.josat.2026.210128. Online ahead of print.ABSTRACTINTRODUCTION: Problematic substance use is widespread, with an estimated one in 25...

J Subst Use Addict Treat. 2026 Oct 3:210126. doi: 10.1016/j.josat.2026.210126. Online ahead of print.ABSTRACTINTRODUCTION: Youth with hearing loss face challenges such as communication barriers in...

J Subst Use Addict Treat. 2026 Oct 3:210134. doi: 10.1016/j.josat.2026.210134. Online ahead of print.ABSTRACTINTRODUCTION: Substance use disorders (SUD) are more prevalent among males than females,...

J Subst Use Addict Treat. 2026 Oct 3:210131. doi: 10.1016/j.josat.2026.210131. Online ahead of print.ABSTRACTBACKGROUND: Substance use disorders frequently co-occur with severe mental illness (SMI), and...

J Affect Disord. 2026 Oct 3:122585. doi: 10.1016/j.jad.2026.122585. Online ahead of print.ABSTRACTBACKGROUND: Post-traumatic stress disorder (PTSD) is characterized by negative affective symptoms, including anxiety, depression,...

Forensic Sci Rev. 2026 Jul;38(2):111-128.ABSTRACTPoisoning by acetaminophen is a serious public health concern because of its accessibility and the ease with which overdoses can occur...

J Psychiatr Res. 2026 Sep 29;203:305-312. doi: 10.1016/j.jpsychires.2026.09.028. Online ahead of print.ABSTRACTOBJECTIVES: Homelessness and cannabis use may interconnect in complex ways. This study used a...

Int Urol Nephrol. 2026 Oct 3. doi: 10.1007/s11255-026-05409-5. Online ahead of print.ABSTRACTClean intermittent self-catheterization (CISC) is the reference treatment for neurogenic and non-neurogenic voiding dysfunction,...

Community Ment Health J. 2026 Oct 3. doi: 10.1007/s10597-026-01675-w. Online ahead of print.ABSTRACTPsychiatric multimorbidity, defined as the co-occurrence of two or more psychiatric diagnoses, is...

J Paediatr Child Health. 2026 Oct 3. doi: 10.1111/jpc.70605. Online ahead of print.ABSTRACTBACKGROUND: Adolescent vaping is rising globally and in Australia, and evidence on paediatricians'...

Religions (Basel). 2026 May;17(5):569. doi: 10.3390/rel17050569. Epub 2026 May 8.ABSTRACTWe examined whether change in childhood religious affiliation (i.e., religious change) is associated with increased rates...

Addict Res Theory. 2026 Jun 1. doi: 10.1080/16066359.2026.2678461. Online ahead of print.ABSTRACTDespite recent increases in gabapentin misuse among Black Americans who use opioids, there is...

Front Psychol. 2026 Sep 18;17:1679968. doi: 10.3389/fpsyg.2026.1679968. eCollection 2026.ABSTRACTBACKGROUND: Many digital mental health interventions (DMHIs) can be effective in reducing symptoms of common mental health...

Biol Psychiatry Glob Open Sci. 2026 Sep 21;6(6):100806. doi: 10.1016/j.bpsgos.2026.100806. eCollection 2026 Nov.NO ABSTRACTPMID:42828178 | PMC:PMC13631883 | DOI:10.1016/j.bpsgos.2026.100806

Prev Med. 2026 Oct 2:108674. doi: 10.1016/j.ypmed.2026.108674. Online ahead of print.ABSTRACTOBJECTIVE: Alcohol-related morbidity and mortality have risen in recent years while the U.S. confronts a...

Int J Psychophysiol. 2026 Oct 2:113484. doi: 10.1016/j.ijpsycho.2026.113484. Online ahead of print.ABSTRACTThe increasing prevalence of Cannabis Use Disorder (CUD) necessitates measures that reliably predict outcomes....

J Subst Use Addict Treat. 2026 Oct 2:210133. doi: 10.1016/j.josat.2026.210133. Online ahead of print.ABSTRACTINTRODUCTION: Alcohol Behavioral Couple Therapy (ABCT) is an efficacious treatment for Alcohol...

Drug Alcohol Depend. 2026 Sep 28;288:113378. doi: 10.1016/j.drugalcdep.2026.113378. Online ahead of print.ABSTRACTBACKGROUND: E-cigarettes (ECs) remain the most commonly used tobacco product among young people in...

Acta Psychol (Amst). 2026 Oct 2;270:107883. doi: 10.1016/j.actpsy.2026.107883. Online ahead of print.ABSTRACTBACKGROUND: Adolescence is associated with substantial improvements in cognitive performance, with faster and more...

Addict Behav. 2026 Oct 1;184:108872. doi: 10.1016/j.addbeh.2026.108872. Online ahead of print.ABSTRACTOBJECTIVES: This study examined the association between avoidance coping and prenatal cannabis use among Black...

Addict Behav. 2026 Sep 25;184:108865. doi: 10.1016/j.addbeh.2026.108865. Online ahead of print.ABSTRACTOBJECTIVES: Non-alcoholic beer may help adults reduce alcohol intake, but it could also undermine alcohol...

South Med J. 2026 Oct 2;119(10):614-619. doi: 10.14423/SMJ.0000000000002021.ABSTRACTOBJECTIVE: The objective of this study was to evaluate the effect of intrauterine buprenorphine exposure during pregnancy on...

JMIR Ment Health. 2026 Sep 30;13:e105052. doi: 10.2196/105052.ABSTRACTBACKGROUND: Generative AI (GenAI) tools, such as OpenAI's ChatGPT, Google's Gemini, and Microsoft Copilot, are being adopted across...

Bioorg Med Chem Lett. 2026 Sep 30:130788. doi: 10.1016/j.bmcl.2026.130788. Online ahead of print.ABSTRACTWe here report the discovery of a series of fluoro-substituted 3-phenoxy-azetidines useful for...

Prog Biophys Mol Biol. 2026 Sep 30:101958. doi: 10.1016/j.pbiomolbio.2026.101958. Online ahead of print.ABSTRACTBACKGROUND: Quantum biology has shown that selected biological processes depend on quantum effects,...

Pharmacol Biochem Behav. 2026 Sep 30:174274. doi: 10.1016/j.pbb.2026.174274. Online ahead of print.ABSTRACTRats emit 50-kHz ultrasonic vocalizations (USVs), a widely used measure of drug-induced motivational and...

Glob Public Health. 2026 Dec 31;21(1):2740891. doi: 10.1080/17441692.2026.2740891. Epub 2026 Sep 30.ABSTRACTFor almost three decades, compulsory detention has shaped Vietnam's response to illicit drug use....

Psychiatry Res Neuroimaging. 2026 Sep 23;364:112343. doi: 10.1016/j.pscychresns.2026.112343. Online ahead of print.ABSTRACTBACKGROUND: Accelerated resting-state fMRI (rs-fMRI) may reduce scan time and participant burden, but whether...

Ultrason Sonochem. 2026 Sep 27;134:108064. doi: 10.1016/j.ultsonch.2026.108064. Online ahead of print.ABSTRACTUltrasound-induced cavitation plays an important role in ultrasound-mediated treatments, drug delivery, and sonodynamic therapy, yet...

J Chromatogr A. 2026 Sep 24;1788:467490. doi: 10.1016/j.chroma.2026.467490. Online ahead of print.ABSTRACTNaturally occurring narcotics such as morphine and codeine require careful monitoring due to the...

Int J Drug Policy. 2026 Sep 30;157(Pt A):105521. doi: 10.1016/j.drugpo.2026.105521. Online ahead of print.ABSTRACTSubstance use disorder (SUD) is a multifaceted crisis shaped by the interaction...

Inquiry. 2026 Jan-Dec;63:469580261468779. doi: 10.1177/00469580261468779. Epub 2026 Sep 30.ABSTRACTIntroductionThe widespread use of smartphones and digital platforms has increased the risk of technological addictions among university...

J Neurosci. 2026 Sep 29:e0892262026. doi: 10.1523/JNEUROSCI.0892-26.2026. Online ahead of print.ABSTRACTOur environment is complex and to navigate it effectively, we organize conceptual and spatial information...

J Epidemiol Community Health. 2026 Sep 28:jech-2025-225502. doi: 10.1136/jech-2025-225502. Online ahead of print.ABSTRACTBACKGROUND: Marginalisation has been proposed as a risk factor for the development of...

Soins Psychiatr. 2026 Sep-Oct;47(366):45-48. doi: 10.1016/j.spsy.2026.07.011. Epub 2026 Sep 11.ABSTRACTThe co-occurrence of a psychiatric disorder and a substance use disorder affects many patients in adult...

BMJ Open. 2026 Sep 28;16(9):e124416. doi: 10.1136/bmjopen-2026-124416.ABSTRACTOBJECTIVES: To update estimates of the health and financial burden of adverse childhood experiences (ACEs) in England and Wales...

Br J Pharmacol. 2026 Sep 28. doi: 10.1111/bph.70678. Online ahead of print.ABSTRACTBACKGROUND AND PURPOSE: Nicotine dependence remains one of the leading causes of morbidity and...

Neuropharmacology. 2026 Sep 28:111201. doi: 10.1016/j.neuropharm.2026.111201. Online ahead of print.ABSTRACTThe opioid crisis has intensified over recent decades, largely driven by the widespread and often indiscriminate...

Brain Behav Immun. 2026 Sep 28:107035. doi: 10.1016/j.bbi.2026.107035. Online ahead of print.ABSTRACTBACKGROUND: Alcohol use disorder (AUD) is frequently comorbid with anxiety and depression, conditions closely...

Crit Rev Oncol Hematol. 2026 Sep 28:105628. doi: 10.1016/j.critrevonc.2026.105628. Online ahead of print.ABSTRACTAcute myeloid leukaemia (AML) remains associated with poor outcomes in relapsed or refractory...

Mol Cell. 2026 Sep 28:S1097-2765(26)00626-X. doi: 10.1016/j.molcel.2026.09.006. Online ahead of print.ABSTRACTPoly(ADP-ribose) polymerase inhibitors (PARPi) exploit homologous recombination (HR) deficiency in BRCA1/2-mutant cancers to induce synthetic...