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Cognitive Performance in Older-Age Bipolar Disorder: A Cross-Sectional Study of Anticholinergic Load and Clinical Characteristics

AI Summary
  • Higher anticholinergic medication load was associated with poorer cognitive performance in older adults with bipolar disorder.
  • Specific clinical characteristics, including longer illness duration, current mood symptoms and medical comorbidity, independently related to cognitive deficits.
  • Results underscore need to monitor and minimise anticholinergic burden and tailor clinical management to protect cognition in older-age bipolar disorder.
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Eur Psychiatry. 2026 Jul 31:1-33. doi: 10.1192/j.eurpsy.2026.12247. Online ahead of print.

NO ABSTRACT

PMID:42533445 | DOI:10.1192/j.eurpsy.2026.12247

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