Evidence
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Latest: Psychiatryai.com #RAISR4D Evidence
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Cool Evidence: Engaging Young People and Students in Real-World Evidence
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Real-Time Evidence Search [Psychiatry]
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AI Research
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Introduction to single cell RNA sequencing data analysis
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🌐 90 Days
AI Virtual Reality Related Evidence Matrix
Anchored-fusion enables targeted fusion search in bulk and single-cell RNA sequencing data Comparative Analysis of Single-Cell RNA Sequencing Methods with and without Sample Multiplexing Transcriptomics of Human Brain Tissue in Parkinson's Disease: a Comparison of Bulk and Single-cell RNA Sequencing Multiscale approaches for understanding single cell spatial omics data Evaluating performance and applications of sample-wise cell deconvolution methods on human brain transcriptomic data Evaluating performance and applications of sample-wise cell deconvolution methods on human brain transcriptomic data A single-cell and spatial RNA-seq database for Alzheimer's disease (ssREAD) Analysis and Visualization of Single-Cell Sequencing Data with Scanpy and MetaCell: A Tutorial Proteomic analysis of pleomorphic dermal sarcoma reveals a fibroblastic cell of origin and distinct immune evasion mechanisms Evaluating performance and applications of sample-wise cell deconvolution methods on human brain transcriptomic data Advancements in Single-Cell RNA Sequencing Research for Neurological Diseases Haploinsufficiency of phosphodiesterase 10A activates PI3K/AKT signaling independent of PTEN to induce an aggressive glioma phenotype Detection of circulating tumor cells by means of machine learning using Smart-Seq2 sequencing Protocol to perform integrative analysis of high-dimensional single-cell multimodal data using an interpretable deep learning technique Molecular cascades and cell type-specific signatures in ASD revealed by single-cell genomics Molecular cascades and cell type-specific signatures in ASD revealed by single-cell genomics FinaleMe: Predicting DNA methylation by the fragmentation patterns of plasma cell-free DNA Characterizing dysregulations via cell-cell communications in Alzheimer's brains using single-cell transcriptomes Ocean to Tree: Leveraging Single-Molecule RNA-Seq to Repair Genome Gene Models and Improve Phylogenomic Analysis of Gene and Species Evolution Single-cell RNA-seq reveals the role of YAP1 in prefrontal cortex microglia in depression Artificial intelligence-assisted automatic and index-based microbial single-cell sorting system for One-Cell-One-Tube Causal gene regulatory analysis with RNA velocity reveals an interplay between slow and fast transcription factors Single-cell RNA-seq data analysis reveals functionally relevant biomarkers of early brain development and their regulatory footprints in human embryonic stem cells (hESCs) Library size confounds biology in spatial transcriptomics data Transcriptional programs mediating neuronal toxicity and altered glial-neuronal signaling in a Drosophila knock-in tauopathy model Assessing transcriptomic heterogeneity of single-cell RNASeq data by bulk-level gene expression data Clinically unfavorable transcriptome subtypes of non-WNT/non-SHH medulloblastomas are associated with a predominance in proliferating and progenitor-like cell subpopulations Clinically unfavorable transcriptome subtypes of non-WNT/non-SHH medulloblastomas are associated with a predominance in proliferating and progenitor-like cell subpopulations Single-Cell Nuclear Sequencing Atlas Revealed the Induction of Parkinson's Disease by RELN+ Neuron 3 and the Gene Regulatory Network of MSRA Osteopontin drives neuroinflammation and cell loss in MAPT-N279K frontotemporal dementia patient neurons Single cell RNA sequencing reveals immunomodulatory mechanism of stem cell factor and granulocyte colony-stimulating factor treatment in the brains of aged APP/PS1 mice Machine learning algorithms integrate bulk and single-cell RNA data to unveil oxidative stress following intracerebral hemorrhage HPV16-miRNAs exert oncogenic effects through enhancers in human cervical cancer Spatial genomics: mapping human steatotic liver disease Spatially Resolved Single-Cell Omics: Methods, Challenges, and Future Perspectives Unveiling the role of disulfidptosis-related genes in the pathogenesis of non-alcoholic fatty liver disease The Clinical Utility of a Tiered Approach to Pediatric Glioma Molecular Characterization for Resource-Limited Settings Transcriptomic Evaluation of a Stress Vulnerability Network using Single Cell RNA-Seq in mouse Prefrontal Cortex Antitumor efficacy and potential mechanism of FAP-targeted radioligand therapy combined with immune checkpoint blockade Therapeutic potential of targeting Nrf2 by panobinostat in pituitary neuroendocrine tumors Characterisation of premature cell senescence in Alzheimer's disease using single nuclear transcriptomics Single-Cell Data Analysis Reveals Critical Hepatic Cells Subpopulations in the Progression of Non-alcoholic Fatty Liver Disease to Non-Alcoholic Steatohepatitis Single-cell transcriptomic analysis of decidual immune cell landscape in the occurrence of adverse pregnancy outcomes induced by Toxoplasma gondii infection Single-cell transcriptomic analysis of decidual immune cell landscape in the occurrence of adverse pregnancy outcomes induced by Toxoplasma gondii infection Integrating Bulk RNA and Single-Cell Sequencing Data Unveils Efferocytosis Patterns and ceRNA Network in Ischemic Stroke Dissecting Parkinson's disease with long-read RNA-sequencing Drugs of abuse hijack a mesolimbic pathway that processes homeostatic need Hofbauer cells and fetal brain microglia share transcriptional profiles and responses to maternal diet-induced obesity Hofbauer cells and fetal brain microglia share transcriptional profiles and responses to maternal diet-induced obesity SpatialPrompt: spatially aware scalable and accurate tool for spot deconvolution and domain identification in spatial transcriptomics Single-cell genomics and regulatory networks for 388 human brains Single-cell genomics and regulatory networks for 388 human brains Single-cell genomics and regulatory networks for 388 human brains Protein Research Seminar LINC00894 inhibited neuron cellular apoptosis and regulated activating transcription factor 3 expression Systematic analysis of RNA-binding proteins identifies targetable therapeutic vulnerabilities in osteosarcoma Supermultipotency and unpredictability in the developing superior colliculus Single-Cell Multi-Omics Map of Cell Type-Specific Mechanistic Drivers of Multiple Sclerosis Lesions Detecting differential transcript usage in complex diseases with SPIT Systems biology dissection of PTSD and MDD across brain regions, cell types, and blood Omics approaches to investigate the pathogenesis of suicide scRank infers drug-responsive cell types from untreated scRNA-seq data using a target-perturbed gene regulatory network Accurate and comprehensive evaluation of O6-methylguanine-DNA methyltransferase promoter methylation by nanopore sequencing The microtubule targeting agent ST-401 triggers cell death in interphase and prevents the formation of polyploid giant cancer cells
Evidence Blueprint
Introduction to single cell RNA sequencing data analysis
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Introduction to single cell RNA sequencing data analysis
🌐 365 Days
AI Virtual Reality Related Evidence Matrix
Single-Nucleus RNA-Sequencing in Brain Tissue A targeted sequencing extension for transcript genotyping in single-cell transcriptomics Anchored-fusion enables targeted fusion search in bulk and single-cell RNA sequencing data Full-length single-cell RNA-sequencing: From short to long-reads Comparative Analysis of Single-Cell RNA Sequencing Methods with and without Sample Multiplexing Transcriptomics of Human Brain Tissue in Parkinson's Disease: a Comparison of Bulk and Single-cell RNA Sequencing Single-Cell RNA-Sequencing in Astrocyte Development, Heterogeneity, and Disease Rabies virus-based barcoded neuroanatomy resolved by single-cell RNA and in situ sequencing Multiscale approaches for understanding single cell spatial omics data Advance and Application of Single-cell Transcriptomics in Auditory Research Evaluating performance and applications of sample-wise cell deconvolution methods on human brain transcriptomic data Evaluating performance and applications of sample-wise cell deconvolution methods on human brain transcriptomic data hdWGCNA identifies co-expression networks in high-dimensional transcriptomics data Human γδ T cell Identification from Single-cell RNA Sequencing Datasets by Modular TCR Expression A single-cell and spatial RNA-seq database for Alzheimer's disease (ssREAD) Analysis and Visualization of Single-Cell Sequencing Data with Scanpy and MetaCell: A Tutorial Dissecting viral infections, one cell at a time, by single-cell technologies Single-cell RNA sequencing uncovers the cell type-dependent transcriptomic changes in the retrosplenial cortex after peripheral nerve injury Proteomic analysis of pleomorphic dermal sarcoma reveals a fibroblastic cell of origin and distinct immune evasion mechanisms Evaluating performance and applications of sample-wise cell deconvolution methods on human brain transcriptomic data Differential variability analysis of single-cell gene expression data Hemocyte Nuclei Isolation from Adult Drosophila melanogaster for snRNA-seq The role of NF-κB signaling pathway in reactive astrocytes among neurodegeneration after methamphetamine exposure by integrated bioinformatics Leveraging spatial transcriptomics data to recover cell locations in single-cell RNA-seq with CeLEry Advancements in Single-Cell RNA Sequencing Research for Neurological Diseases Single-cell long-read sequencing in human cerebral organoids uncovers cell-type-specific and autism-associated exons Isolation and profiling of viable tumor cells from human ex vivo glioblastoma cultures through single-cell transcriptomics Haploinsufficiency of phosphodiesterase 10A activates PI3K/AKT signaling independent of PTEN to induce an aggressive glioma phenotype Detection of circulating tumor cells by means of machine learning using Smart-Seq2 sequencing Protocol to perform integrative analysis of high-dimensional single-cell multimodal data using an interpretable deep learning technique Slide-tags enables single-nucleus barcoding for multimodal spatial genomics Single-cell RNA sequencing reveals diverse B cell phenotypes in patients with anti-NMDAR encephalitis Molecular cascades and cell type-specific signatures in ASD revealed by single-cell genomics Molecular cascades and cell type-specific signatures in ASD revealed by single-cell genomics Single-cell transcriptomic sequencing identifies subcutaneous patient-derived xenograft recapitulated medulloblastoma Single-Cell Transcriptomics and In Vitro Lineage Tracing Reveals Differential Susceptibility of Human iPSC-Derived Midbrain Dopaminergic Neurons in a Cellular Model of Parkinson's Disease An overview of human single-cell RNA sequencing studies in neurobiological disease ASCL1 induces neurogenesis in human Müller glia FinaleMe: Predicting DNA methylation by the fragmentation patterns of plasma cell-free DNA METTL3 drives NAFLD-related hepatocellular carcinoma and is a therapeutic target for boosting immunotherapy Deciphering early human pancreas development at the single-cell level Characterizing dysregulations via cell-cell communications in Alzheimer's brains using single-cell transcriptomes Cell-type deconvolution of bulk-blood RNA-seq reveals biological insights into neuropsychiatric disorders High throughput functional profiling of genes at intraocular pressure loci reveals distinct networks for glaucoma Ocean to Tree: Leveraging Single-Molecule RNA-Seq to Repair Genome Gene Models and Improve Phylogenomic Analysis of Gene and Species Evolution Cell-type composition affects adipose gene expression associations with cardiometabolic traits Single-cell RNA-seq reveals the role of YAP1 in prefrontal cortex microglia in depression Inferring cellular and molecular processes in single-cell data with non-negative matrix factorization using Python, R and GenePattern Notebook implementations of CoGAPS Artificial intelligence-assisted automatic and index-based microbial single-cell sorting system for One-Cell-One-Tube Causal gene regulatory analysis with RNA velocity reveals an interplay between slow and fast transcription factors Expression Atlas update: insights from sequencing data at both bulk and single cell level Common mitochondrial deletions in RNA-Seq: evaluation of bulk, single-cell, and spatial transcriptomic datasets Single-cell RNA-seq data analysis reveals functionally relevant biomarkers of early brain development and their regulatory footprints in human embryonic stem cells (hESCs) Library size confounds biology in spatial transcriptomics data A chemist’s adventures in immunology: Probing the T-cell activation pathway at the single cell and single molecule-level with n... Transcriptional programs mediating neuronal toxicity and altered glial-neuronal signaling in a Drosophila knock-in tauopathy model Assessing transcriptomic heterogeneity of single-cell RNASeq data by bulk-level gene expression data Single-Nucleus Transcriptome Profiling of Dorsolateral Prefrontal Cortex: Mechanistic Roles for Neuronal Gene Expression, Including the 17q21.31 Locus, in PTSD Stress Response A single-nucleus transcriptome-wide association study implicates novel genes in depression pathogenesis Clinically unfavorable transcriptome subtypes of non-WNT/non-SHH medulloblastomas are associated with a predominance in proliferating and progenitor-like cell subpopulations Clinically unfavorable transcriptome subtypes of non-WNT/non-SHH medulloblastomas are associated with a predominance in proliferating and progenitor-like cell subpopulations Psychiatric risk gene Transcription Factor 4 (TCF4) regulates the density and connectivity of distinct inhibitory interneuron subtypes TrkB-dependent regulation of molecular signaling across septal cell types Single-Cell Nuclear Sequencing Atlas Revealed the Induction of Parkinson's Disease by RELN+ Neuron 3 and the Gene Regulatory Network of MSRA