Evidence
Eur Child Adolesc Psychiatry. 2024 Jul 22. doi: 10.1007/s00787-024-02539-y. Online ahead of print.
ABSTRACT
OBJECTIVES: Van der Knaap disease or megalencephalic leukoencephalopathy with subcortical cysts (MLC), is a slowly progressive neurodegenerative disease with macrocephaly. We present a case of MLC with a confirmed homozygous MLC1 mutation who presented with a psychotic attack at a very young age.
CASE PRESENTATION: An 11-year-old girl was admitted to the emergency room with delusions, hallucinations, and irritability. She was diagnosed with MLC at 18 months old. Her psychotic symptoms were improved with the administration of risperidone treatment added to her valproic acid treatment for EEG abnormality.
CONCLUSION: In this case study we reported the first episode of a psychotic attack during the clinical course of MLC. This case indicates the possibility that MLC influences the onset of the psychotic attack. Further investigation with more patients is needed to identify the relationship.
PMID:39039223 | DOI:10.1007/s00787-024-02539-y
Estimated reading time: 3 minute(s)
Latest: Psychiatryai.com #RAISR4D Evidence
Cool Evidence: Engaging Young People and Students in Real-World Evidence ☀️
Real-Time Evidence Search [Psychiatry]
AI Research
Psychotic attack during the clinical course of megalencephalic leukoencephalopathy with subcortical cysts: a case report
🌐 90 Days
AI Virtual Reality Related Evidence Matrix
- Expanding the phenotype of NEDAMSS with a psychiatric perspective: analysis of a new case, and a systematic review of the literature
- Idiopathic young-onset Fahr's disease with schizophrenia-like presentation: a case report
- "My sister wants to kill me": A case report and systematic review of literature of co-occurring multiple sclerosis and psychosis
- "My sister wants to kill me": A case report and systematic review of literature of co-occurring multiple sclerosis and psychosis
- THE ROLE OF STRESS IN MANIC-PSYCHOTIC EPISODE DURING THE TERROR ATTACK OF OCTOBER 7 - CASE REPORT
- A case of a cerebellar form of progressive multifocal leukoencephalopathy in a patient undergoing peritoneal dialysis
- A case of a cerebellar form of progressive multifocal leukoencephalopathy in a patient undergoing peritoneal dialysis
- Primary versus secondary psychosis in a patient with congenital liver disease
- Primary versus secondary psychosis in a patient with congenital liver disease
- Early Onset Psychosis in a Pediatric Oncology Setting: A Case Report
- Characteristics of isoniazid-induced psychosis: a systematic review of case reports and case series
- Identification of 22q11.2 deletion in a patient with schizophrenia and clinically diagnosed Rubinstein-Taybi syndrome
- Neurosyphilis Presenting as Psychiatric Symptoms at Younger Age: A Case Report
- Neurosyphilis Presenting as Psychiatric Symptoms at Younger Age: A Case Report
- Paralytic ileus in a patient on clozapine therapy showing an inverted clozapine/norclozapine ratio after switching valproic acid to carbamazepine: a case report
- Paralytic ileus in a patient on clozapine therapy showing an inverted clozapine/norclozapine ratio after switching valproic acid to carbamazepine: a case report
- Drug-induced psychosis following use of Ayahuasca: a presentation to forensic psychiatric services
- Drug-induced psychosis following use of Ayahuasca: a presentation to forensic psychiatric services
- Bipolar disorder and Lewy body dementia: case report and literature review
- Metachronous intracranial meningiomas without dural attachment in a child - Rare case report and review of literature
- Steroid-induced psychosis: a spectrum of neuropsychiatric glucocorticoid side effects
- Stroke in a Young Patient Due to Moyamoya Disease
- Rare presentation of Klüver-Bucy syndrome following subarachnoid hemorrhage
- Rare presentation of Klüver-Bucy syndrome following subarachnoid hemorrhage
- Clinical Reasoning and Challenges Faced With Onset Psychotic Symptoms in a Case of Combined Huntington's Disease and Gayet-Wernicke Encephalopathy
- Clinical Reasoning and Challenges Faced With Onset Psychotic Symptoms in a Case of Combined Huntington's Disease and Gayet-Wernicke Encephalopathy
- Patterns of Self-Reported Mental Health Symptoms and Treatment among People Booked into a Large Metropolitan County Jail
- Acceptance and Commitment Therapy for Patients with a First Psychotic Episode
- Acceptance and Commitment Therapy for Patients with a First Psychotic Episode
- A Case of Personality and Behavioral Changes with Frontotemporal and Cerebellar Atrophy on MRI with Corresponding Hypometabolism on FDG-PET
- On Seizures and Knives: Perampanel-Induced Psychosis: A Case Report and Literature Review
- Electroconvulsive Therapy in Forensic Psychiatry: A Systematic Review
- The clinical course of individuals with 22q11.2 deletion syndrome converting to psychotic disorders: a long-term retrospective follow-up
- The clinical course of individuals with 22q11.2 deletion syndrome converting to psychotic disorders: a long-term retrospective follow-up
- Cavbeta3 Contributes to the Maintenance of the Blood-Brain Barrier and Alleviates Symptoms of Experimental Autoimmune Encephalitis
- Recurrent Psychotic Depression Associated with Chronic Subdural Haematoma: A Case Report
- Prevalence of Psychotic Symptoms in Mild Cognitive Impairment: A Systematic Review and Meta-Analysis
- Prevalence of Psychotic Symptoms in Mild Cognitive Impairment: A Systematic Review and Meta-Analysis
- Distinct neurological phenotypes associated with biallelic loss of NOTCH3 function: evidence for recessive inheritance
- Clinical characteristics and treatment of psychosis in Parkinson's disease: A narrative review
- An Unusual Case of Alcoholic Liver Disease Associated with Secondary IgA Vasculitic Nephritis presenting as Rapidly Progressive Glomerulonephritis
- An Unusual Case of Alcoholic Liver Disease Associated with Secondary IgA Vasculitic Nephritis presenting as Rapidly Progressive Glomerulonephritis
- Histopathological Investigation of Progressive Encephalomyelitis with Rigidity and Myoclonus: An Autopsy Case Characterized by Oculomotor Dysfunction and Autonomic Failure
- Long prodromal symptoms of neuroleptic malignant syndrome in patient with intellectual developmental disorder-A case report
- Artificial intelligence iterative reconstruction in abdominal CT of patients with irregular arm positioning: a case-by-case evaluation
- Effectiveness of Electroconvulsive Therapy in Functional Neurological Disorders: A Case Report
- A four-year-old girl with pathogenic variant in the NAA10 gene and precocious puberty - case report and literature review
- Kufor-Rakeb syndrome-associated psychosis: a novel loss-of-function ATP13A2 variant and response to antipsychotic therapy
- Early-onset Alzheimer dementia superimposed on schizophrenia: a rare case report
- Treatment of Aggressive Behavior and Agitation in an 11-Year-Old Boy with Co-Occurring Autism and ADHD: A Case Report and Literature Review on the Use of Intravenous Valproate in Emergency Psychiatry
- Which diagnoses and arguments regarding severe mental disorder do forensic psychiatric experts in Sweden consider in different cases? A qualitative vignette study
- Diagnostic Challenges in Neuro-Psychiatric Systemic Lupus Erythematosus: A Case of a Patient With Psychosis Secondary to Lupus Cerebritis in the Setting of a Steroid Taper
- Altered temporal lobe connectivity is associated with psychotic symptoms in drug-naive adolescent patients with first-episode schizophrenia
- Navigating Treatment Challenges: A Case Study on Refractory Psychosis in a Chronic MDMA (3,4-Methylenedioxymethamphetamine) User
- A Complex Presentation: Psychosis in a Patient Diagnosed With Lennox-Gastaut Syndrome
- Scurvy presenting in a homeless 32-year-old male: a case report
- Clinical Reasoning: Hyperventilation-Induced Alternating Hemiplegia With Concomitant Hemispheric EEG Slowing in a 7-Year-Old Girl With Headache
- Vitriol attack on a young woman in Greece: The story of Ioanna's response
- Clinical Analysis for Diagnosing Autism in Children Under Two: A Case Report
- Clinical Analysis for Diagnosing Autism in Children Under Two: A Case Report
- Treatment of a resistant case of schizoaffective disorder with lumateperone: A case report
- Mental Health Service Use Before First Diagnosis of a Psychotic Disorder
- The influence of age on ECT efficacy in depression, mania, psychotic depression and schizophrenia: A transdiagnostic analysis
- Delusion of pregnancy: Case series
Evidence Blueprint
Psychotic attack during the clinical course of megalencephalic leukoencephalopathy with subcortical cysts: a case report
☊ AI-Driven Related Evidence Nodes
(recent articles with at least 5 words in title)
More Evidence
Psychotic attack during the clinical course of megalencephalic leukoencephalopathy with subcortical cysts: a case report
🌐 365 Days
AI Virtual Reality Related Evidence Matrix
- Presenilin Gene Mutation-associated Psychosis: Phenotypic Characteristics and Clinical Implications
- Suicidal and Homicidal Thoughts as Psychotic Symptoms in an Adolescent: A Case Report
- Expanding the phenotype of NEDAMSS with a psychiatric perspective: analysis of a new case, and a systematic review of the literature
- Idiopathic young-onset Fahr's disease with schizophrenia-like presentation: a case report
- A case report of a patient with Turner syndrome who develops catatonia secondary to psychotic symptoms
- An Unusual Presentation of Delusional Companion Syndrome: A Case Report and Review of the Literature
- "My sister wants to kill me": A case report and systematic review of literature of co-occurring multiple sclerosis and psychosis
- "My sister wants to kill me": A case report and systematic review of literature of co-occurring multiple sclerosis and psychosis
- THE ROLE OF STRESS IN MANIC-PSYCHOTIC EPISODE DURING THE TERROR ATTACK OF OCTOBER 7 - CASE REPORT
- Methadone Withdrawal-Related Psychosis in a Patient With Hormone-Dependent Breast Cancer: A Case Report
- Brief psychotic disorder related to areca nut use: a case report
- A case of a cerebellar form of progressive multifocal leukoencephalopathy in a patient undergoing peritoneal dialysis
- A case of a cerebellar form of progressive multifocal leukoencephalopathy in a patient undergoing peritoneal dialysis
- Primary versus secondary psychosis in a patient with congenital liver disease
- Primary versus secondary psychosis in a patient with congenital liver disease
- Early Onset Psychosis in a Pediatric Oncology Setting: A Case Report
- Characteristics of isoniazid-induced psychosis: a systematic review of case reports and case series
- Seizures, Psychosis, and Cerebral Vascular Malformation: A Rare Chain of Events
- Ictal Cotard delusion as a manifestation of nonconvulsive status epilepticus: A case report and commentary
- The Challenge of Managing Refractory Psychosis Amid Multiple Medication Side Effects: A Case Report and Review of the Literature
- Identification of 22q11.2 deletion in a patient with schizophrenia and clinically diagnosed Rubinstein-Taybi syndrome
- A rare case report of Huntington's disease with severe psychiatric symptoms as initial manifestations
- Case report-Depression with psychotic features as an atypical presentation of neurosyphilis
- Neurosyphilis Presenting as Psychiatric Symptoms at Younger Age: A Case Report
- Neurosyphilis Presenting as Psychiatric Symptoms at Younger Age: A Case Report
- Review of Risk Factors, Pathophysiology, Management Principles, and Role of Medications
- Gerstmann-Sträussler-Scheinker Disease Presenting as Late-Onset Slowly Progressive Spinocerebellar Ataxia, and Comparative Case Series with Neuropathology
- Paralytic ileus in a patient on clozapine therapy showing an inverted clozapine/norclozapine ratio after switching valproic acid to carbamazepine: a case report
- Paralytic ileus in a patient on clozapine therapy showing an inverted clozapine/norclozapine ratio after switching valproic acid to carbamazepine: a case report
- Psychosis in Neurodegenerative Dementias: A Systematic Comparative Review
- The Emergence of a Psychotic Disorder With a Diagnosis of Breast Cancer Metastasized to the Brain: A Case Report
- Longitudinal associations between psychedelic use and psychotic symptoms in the United States and United Kingdom
- Drug-induced psychosis following use of Ayahuasca: a presentation to forensic psychiatric services
- Drug-induced psychosis following use of Ayahuasca: a presentation to forensic psychiatric services
- Psychotic symptoms are associated with elevated tau PET signal in the amygdala independent of Alzheimer's disease clinical severity and amyloid burden
- Cannabis-induced psychotic disorder with onset during withdrawal: A brief report of emerging evidence
- Hypersexuality during treatment with cariprazine in a patient with schizophrenia? A case report
- Bipolar disorder and Lewy body dementia: case report and literature review
- Cerebellar Leukoencephalopathy following Fentanyl Intoxication. A case report and review of the literature
- Hypothyroidism and sinus dysfunction associated with lithium-paliperidone combination therapy for bipolar disorder with psychotic symptoms: a case report
- Status epilepticus in a pregnant patient with a previously unrecognized POLG-associated disease
- Metachronous intracranial meningiomas without dural attachment in a child - Rare case report and review of literature
- COVID-19 associated psychosis
- A neuropsychiatric case of delayed post-hypoxic leukoencephalopathy from opioid intoxication resulting in Anton-Babinski syndrome and quadriplegia
- Case Report: Guanfacine and methylphenidate improved chronic lower back pain in autosomal dominant polycystic kidney disease with comorbid attention deficit hyperactivity disorder and autism spectrum disorder
- Steroid-induced psychosis: a spectrum of neuropsychiatric glucocorticoid side effects
- Manic episode in a patient with pancreatic adenocarcinoma: a case report
- Stroke in a Young Patient Due to Moyamoya Disease
- Case Report of a 14-Year-Old Girl with Addison's Disease Under Initial Presumptive Diagnosis of Anorexia Nervosa: Confusingly Similar and Yet so Different?
- Ethical challenges in the treatment of psychotic pregnancy denial
- Acute Psychotic Episode Precipitated by Opioid Withdrawal in a Case of Bipolar I Disorder
- Quetiapine and Valproic Acid-induced Central Hypothyroidism in a Patient with Autism Spectrum Disorder and Intractable Epilepsy: A Case Report
- 18q Deletion Syndrome-Associated Schizophrenia: A Case Report
- Positive psychotic symptoms as a marker of clinical severity in a transdiagnostic sample of help-seeking adolescents
- Rare presentation of Klüver-Bucy syndrome following subarachnoid hemorrhage
- Rare presentation of Klüver-Bucy syndrome following subarachnoid hemorrhage
- Case report: clinical improvements observed in first off-label metreleptin treatment of a patient with atypical anorexia nervosa
- Clinical Reasoning and Challenges Faced With Onset Psychotic Symptoms in a Case of Combined Huntington's Disease and Gayet-Wernicke Encephalopathy
- Clinical Reasoning and Challenges Faced With Onset Psychotic Symptoms in a Case of Combined Huntington's Disease and Gayet-Wernicke Encephalopathy
- 18q Deletion Syndrome-Associated Schizophrenia: A Case Report
- Psychotic Experiences and Daily Functioning in Borderline Personality Disorder and Schizophrenia
- Loss-of-function of activity-dependent neuroprotective protein (ADNP) by a splice-acceptor site mutation causes Helsmoortel-Van der Aa syndrome
- Hypertensive emergency due to a delayed dialysis modality transition in a patient with familial hypomagnesemia with hypercalciuria and nephrocalcinosis: a case report
- Hypertensive emergency due to a delayed dialysis modality transition in a patient with familial hypomagnesemia with hypercalciuria and nephrocalcinosis: a case report