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Research progress on the histological scoring system for nonalcoholic fatty liver disease

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Zhonghua Gan Zang Bing Za Zhi. 2023 Jul 20;31(7):765-769. doi: 10.3760/cma.j.cn501113-20230522-00231.

ABSTRACT

Non-alcoholic fatty liver disease (NAFLD) has replaced chronic hepatitis B as the most common chronic liver disease in China and has now been renamed metabolic dysfunction-associated fatty liver disease (MAFLD). The Brunt, the American NASH Clinical Research Network (NASH-CRN), the European Steatosis, Activity, and Fibrosis/Fatty Liver Inhibition of Progression (SAF/FLIP), and the Pediatric NAFLD are currently the four semi-quantitative grading systems for histological evaluation. This paper reviews these four scoring systems for the clinical selection of appropriate systems for diagnosis and prognosis assessment. This article is a review, and in order to coordinate the evaluation criteria of various scoring systems, the old name “NAFLD” is used.

PMID:37580263 | DOI:10.3760/cma.j.cn501113-20230522-00231

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