The role of sirtuin1 in liver injury: molecular mechanisms and novel therapeutic target

2 April 2024

Evidence

PeerJ. 2024 Mar 29;12:e17094. doi: 10.7717/peerj.17094. eCollection 2024.

ABSTRACT

Liver disease is a common and serious threat to human health. The progression of liver diseases is influenced by many physiologic processes, including oxidative stress, inflammation, bile acid metabolism, and autophagy. Various factors lead to the dysfunction of these processes and basing on the different pathogeny, pathology, clinical manifestation, and pathogenesis, liver diseases are grouped into different categories. Specifically, Sirtuin1 (SIRT1), a member of the sirtuin protein family, has been extensively studied in the context of liver injury in recent years and are confirmed the significant role in liver disease. SIRT1 has been found to play a critical role in regulating key processes in liver injury. Further, SIRT1 seems to cause divers outcomes in different types of liver diseases. Recent studies have showed some therapeutic strategies involving modulating SIRT1, which may bring a novel therapeutic target. To elucidate the mechanisms underlying the role of sirtuin1 in liver injury and its potentiality as a therapeutic target, this review outlines the key signaling pathways associated with sirtuin1 and liver injury, and discusses recent advances in therapeutic strategies targeting sirtuin1 in liver diseases.

PMID:38563003 | PMC:PMC10984179 | DOI:10.7717/peerj.17094

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American Journal of Psychiatry, Volume 181, Issue 5, Page 353-358, May 01, 2024.
Jesse D. Hinckley
Understanding and Addressing Widening Racial Inequalities in Drug Overdose 6 May 2024
American Journal of Psychiatry, Volume 181, Issue 5, Page 381-390, May 01, 2024.
Joseph R. Friedman
Harm Reduction for Opioid Use Disorder: Strategies and Outcome Metrics 6 May 2024
American Journal of Psychiatry, Volume 181, Issue 5, Page 372-380, May 01, 2024.
Jennifer D. Ellis

Ramaswamy Viswanathan, M.D., Dr.Med.Sc., Assumes Office of APA President 9 May 2024
Ramaswamy Viswanathan, M.D., Dr.Med.Sc., a longtime advocate for mental health, medical educator, and clinician-researcher, began his term as president of the American Psychiatric Association (APA) at the conclusion of the organization’s 2024 Annual Meeting in New York City.
APAPsychiatric
Steven Starks, M.D., M.B.A., Assumes Office of APA Assembly Speaker 9 May 2024
Steven Starks, M.D., M.B.A., DFAPA, began his one-year term as the Speaker of the American Psychiatric Association (APA) Assembly of District Branches at the close of the organization’s 2024 Annual Meeting in Manhattan.
APAPsychiatric
Study Highlights Key Predictors of Adolescent Substance Use; Special Issue of the American Journal o 6 May 2024
New research, published online today in the American Journal of Psychiatry, examined a broad range of potential predictors of substance use among adolescents and found sociodemographic variables were the most robust predictors of substance use initiation.
APAPsychiatric

RCPsych calls for an end to children’s eating disorders crisis 29 February 2024
New analysis shows child and adolescent eating disorder services have never achieved NHS waiting time targets.
www.rcpsych.ac.uk
Physician Associates Update February 2024 6 February 2024
Dr Lade Smith CBE, President of the Royal College of Psychiatrists, has issued a statement about Physician Associates and the role they have to play.
www.rcpsych.ac.uk
Suspected drugs deaths up in Scotland as hospital admissions fall 1 February 2024
Suspected deaths in Scotland have increased by 11% in the latest quarterly data.
www.rcpsych.ac.uk

Canadian Network for Mood and Anxiety Treatments (CANMAT) 2023 Update on Clinical Guidelines for Management of Major Depressive Disorder in Adults: Réseau canadien pour les traitements de l'humeur et de l'anxiété (CANMAT) 2023 : Mise à jour des lignes directrices cliniques pour la prise en charge du trouble dépressif majeur chez les adultes 7 May 2024
The Canadian Journal of Psychiatry, Ahead of Print. BackgroundThe Canadian Network for Mood and Anxiety Treatments (CANMAT) last published clinical guidelines for the management of major depressive disorder (MDD) in 2016. Owing to advances in the field, an update was needed to incorporate new evidence and provide new and revised recommendations for the assessment and […]
Raymond W. Lam
The Role of Dietary Patterns and Nutritional Supplements in the Management of Mental Disorders in Children and Adolescents: An Umbrella Review of Meta-Analyses: Le rôle des habitudes alimentaires et des suppléments nutritionnels dans la prise en charge des troubles mentaux chez les enfants et les adolescents : une méta-revue de méta-analyses 1 May 2024
The Canadian Journal of Psychiatry, Ahead of Print. ObjectiveIn recent years, the relationship between nutrition and mental health has gained considerable interest. We identified, synthesized, and appraised all meta-analyses of randomized controlled trials (RCTs) and observational studies reporting on the efficacy of dietary patterns and nutrient supplements in the prevention and treatment of mental disorders […]
Maria Talib
Investigating Alexithymia as a Moderator of Outcomes in a Randomized Controlled Trial of an Online Intervention for Co-Occurring Depression and Hazardous Alcohol Use: Enquête sur l'alexithymie en tant que modérateur des résultats dans un essai randomisé contrôlé d'une intervention en ligne pour la dépression concomitante et la consommation dangereuse d'alcool 29 April 2024
The Canadian Journal of Psychiatry, Ahead of Print. ObjectiveAlexithymia is characterized by difficulty identifying and/or describing emotions, reduced imaginal processes, and externally oriented thinking. High levels of alexithymia may increase the challenge of supporting individuals with co-occurring depression and hazardous alcohol use. This secondary analysis sought to investigate whether or not alexithymia moderated the outcomes […]
Christina Schell

Tracking the 3-year trajectory of referrals to an early psychosis intervention service 9 May 2024
Australasian Psychiatry, Ahead of Print. AimTo review the baseline and clinical characteristics of patients referred to a New Zealand Early Psychosis Intervention (EPI) service across a 4-year timeframe.MethodWe compared two cohorts, and identified variables associated with being accepted or declined, and reasons for decline, by an EPI service between 2013 and 2017.ResultsThere were 576 people […]
Nirupamal Pitigala
Knowledge and attitudes towards eating disorders: A survey of psychiatrists and psychiatry trainees in New South Wales 6 May 2024
Australasian Psychiatry, Ahead of Print. ObjectiveTo evaluate New South Wales (NSW) psychiatrists’ and psychiatry trainees’ knowledge and attitudes towards eating disorders (EDs).MethodA total of 1781 psychiatrists and trainees in NSW were invited to complete an anonymous questionnaire assessing ED confidence, knowledge and attitudes.ResultsA total of 51 doctors responded to the survey, with 38 completing all […]
Elsie Jing
Rapidly expanding gender-affirming care based on consensus instead of evidence justifies rigorous governance and transparency 30 April 2024
Australasian Psychiatry, Ahead of Print. ObjectivePublic services offering gender-affirming care to minors have rapidly expanded across Australia. Despite limited evidence of safety and efficacy, no public information about these services is routinely available. Data from freedom of information requests sent to Australian public gender services for minors is summarised. Gender service numbers increased rapidly in […]
Andrew James Amos

Views held by South African primary health care nurses on caring for people living with mental illness 3 May 2024
Background: Primary healthcare is the first point of entry into the healthcare system. Scaling up primary mental healthcare is recommended in South African mental health policy. However, there is a paucity of data exploring the views of primary healthcare nurses (PHCNs) with regards to caring for people living with mental illness (PLWMI) in South Africa.Aim: To explore […]
Nokukhanya Phungula
Long-term benzodiazepine prescriptions in community psychiatry clinics 3 May 2024
Background: Anecdotal evidence indicates that the prevalence of long-term benzodiazepine prescription is high and not in accordance with accepted prescribing guidelines.Aim: To determine the prevalence of long-term prescriptions of benzodiazepines and associations thereof in community psychiatry clinics.Setting: Of the 27 community psychiatry clinics, 5 were randomly selected.Methods: A descriptive, retrospective, and cross-sectional record review of files of 126 adult […]
Machipi A. Tau
Psychiatric nurses advocating for the human rights of mental health care users in Gauteng 2 May 2024
Background: Psychiatric nurses play an important role in advocating for mental health care users such as advocating for the care, treatment and rehabilitation of mental health care users (MHCUs). Psychiatric nurses face various challenges while advocating for the human rights of MHCUs, particularly those unable to protect their rights because of the severity of their mental […]
Nompumelelo Ntshingila

Standards for randomized controlled trials of efficacy of psychological treatments 10 May 2024
World Psychiatry, Volume 23, Issue 2, Page 286-287, June 2024.
David C. Mohr
The future of dynamic networks in research and clinical practice 10 May 2024
World Psychiatry, Volume 23, Issue 2, Page 288-289, June 2024.
Laura F. Bringmann
Algorithm‐based modular psychotherapy vs. cognitive‐behavioral therapy for patients with depression, psychiatric comorbidities and early trauma: a proof‐of‐concept randomized controlled trial 10 May 2024
World Psychiatry, Volume 23, Issue 2, Page 257-266, June 2024.
Elisabeth Schramm, Moritz Elsaesser, Carolin Jenkner, Martin Hautzinger, Sabine C. Herpertz

Occurrence and characteristics of suicidal ideation in psychiatrically healthy individuals based on ecological momentary assessment 10 May 2024
Molecular Psychiatry, Published online: 10 May 2024; doi:10.1038/s41380-024-02560-2Occurrence and characteristics of suicidal ideation in psychiatrically healthy individuals based on ecological momentary assessment
Maria A. Oquendo
Functional connectivity of the amygdala subnuclei in various mood states of bipolar disorder 9 May 2024
Molecular Psychiatry, Published online: 09 May 2024; doi:10.1038/s41380-024-02580-yFunctional connectivity of the amygdala subnuclei in various mood states of bipolar disorder
Sidney Krystal
Genetic regulation of human brain proteome reveals proteins implicated in psychiatric disorders 9 May 2024
Molecular Psychiatry, Published online: 09 May 2024; doi:10.1038/s41380-024-02576-8Genetic regulation of human brain proteome reveals proteins implicated in psychiatric disorders
Jie Luo

Keep calm and make neurons: The effects of glucocorticoids on human cortical neurogenesis
Maternal well-being is important for the development of the fetus, with a key influence on its nervous system. In this issue of , Krontira et al. implicate glucocorticoids, the stress hormones, in the regulation of neural stem cell identity and proliferation, with long-lasting consequences on brain architecture and educational attainment.Maternal well-being is important for the development […]
More than meets the eye: A conserved sensorimotor reflex helps unravel the circuit mechanisms of ASD
Animal models are instrumental to understanding the mechanisms underlying autism spectrum disorder, yet translating human behavioral phenotypes remains challenging. Wang et al. leverage a conserved sensorimotor reflex to elucidate synaptic deficits in haploinsufficiency and pilot novel rescue strategies.Animal models are instrumental to understanding the mechanisms underlying autism spectrum disorder, yet translating human behavioral phenotypes remains challenging. […]
Collaterals and stroke reperfusion: Too few leads to too much
Adequate reperfusion after ischemic stroke is a major determinant of functional outcome yet remains unpredictable and insufficient for most survivors. In this issue of , Binder et al. identify leptomeningeal collaterals (LMCs) in mice and human patients as a key factor in regulating reperfusion and hemorrhagic transformation following stroke.Adequate reperfusion after ischemic stroke is a major […]

Predicting suicidality with small sets of interpretable reward behavior and survey variables 9 May 2024
Nature Mental Health, Published online: 09 May 2024; doi:10.1038/s44220-024-00229-xApplying machine learning to an objective framework for suicidality, the authors demonstrate that four suicidal thought and behavior variables can be predicted with high accuracy and may present a scalable system for suicide risk assessment.
Shamal Lalvani
Rethinking technology innovation for mental health: framework for multi-sectoral collaboration 3 May 2024
Nature Mental Health, Published online: 03 May 2024; doi:10.1038/s44220-024-00232-2In this Perspective, the authors make recommendations on better aligning stakeholders, including those in technology, practitioners and researchers, to increase collaboration and governance in technology and mental health.
Jina Suh
Optimizing real-world benefit and risk of new psychedelic medications: the need for innovative postmarket surveillance 3 May 2024
Nature Mental Health, Published online: 03 May 2024; doi:10.1038/s44220-024-00233-1In this Perspective, authors argue for a more robust and comprehensive postmarket surveillance program of psychedelic-assisted psychotherapy to better ensure safe, appropriate and equitable care for patients.
Joshua C. Black

Faster bi-stable visual switching in psychosis 7 May 2024
Translational Psychiatry, Published online: 07 May 2024; doi:10.1038/s41398-024-02913-zFaster bi-stable visual switching in psychosis
Kyle W. Killebrew
Effects of ebselen addition on emotional processing and brain neurochemistry in depressed patients unresponsive to antidepressant medication 7 May 2024
Translational Psychiatry, Published online: 07 May 2024; doi:10.1038/s41398-024-02899-8Effects of ebselen addition on emotional processing and brain neurochemistry in depressed patients unresponsive to antidepressant medication
Fitri Fareez Ramli
Exploring the role of neuronal-enriched extracellular vesicle miR-93 and interoception in major depressive disorder 27 April 2024
Translational Psychiatry, Published online: 27 April 2024; doi:10.1038/s41398-024-02907-xExploring the role of neuronal-enriched extracellular vesicle miR-93 and interoception in major depressive disorder
Kaiping Burrows

Prospective open-label trial with rituximab in patients with chronic inflammatory demyelinating polyradiculoneuropathy not responding to conventional immune therapies 10 May 2024
BackgroundTo evaluate the efficacy of rituximab in chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) patients not responding to conventional immune therapies.MethodsAn open-label, prospective exploratory study was conducted with intravenous rituximab on 17 CIDP patients who had not responded to at least two first-line therapies. The primary endpoint was to determine the proportion of patients who showed improvement […]
Doneddu, P. E., Cocito, D., Fazio, R., Benedetti, L., Peci, E., Liberatore, G., Falzone, Y. M., Germano, F., Gallia, F., Giannotta, C., Lleixa, C., Bianchi, E., Nobile-Orazio, E.
Efficacy, safety and tolerability of rozanolixizumab in patients with chronic inflammatory demyelinating polyradiculoneuropathy: a randomised, subject-blind, investigator-blind, placebo-controlled, phase 2a trial and open-label extension study 10 May 2024
BackgroundChronic inflammatory demyelinating polyradiculoneuropathy (CIDP) is a peripheral nerve disorder characterised by weakness and sensory loss. We assessed the neonatal Fc receptor inhibitor rozanolixizumab for CIDP management.MethodsCIDP01 (NCT03861481) was a randomised, subject-blind, investigator-blind, placebo-controlled, phase 2a study. Adults with definite or probable CIDP receiving subcutaneous or intravenous immunoglobulin maintenance therapy were randomised 1:1 to 12 […]
Querol, L., De Seze, J., Dysgaard, T., Levine, T., Rao, T. H., Rivner, M., Hartung, H.-P., Kiessling, P., Shimizu, S., Marmol, D., Bozorg, A., Colson, A.-O., Massow, U., Eftimov, F., CIDP01 Study Investigators, Bleecker, Claeys, Debien, Noordhout, Sommer, Garz, Stettner, Schmidt, Fernandez, Gamez, Segura, Morales, Hewamadduma, Haslam, Quarles, Gable
CIDP trials and tribulations 10 May 2024
Two publications in JNNP explore the potential utility of therapies with differing mechanisms of action for the treatment of chronic inflammatory demyelinating polyradiculoneuropathy (CIDP). Querol et al evaluate the neonatal Fc receptor blocker rozanolixizumab, while Doneddu et al study the anti-CD20 therapeutic monoclonal rituximab.1 2 These agents, respectively, lower serum IgG levels or primarily target […]
Rinaldi, S.

Neurocognitive correlates of metabolic dysregulation in individuals with mood disorders: a systematic review and meta-analysis 7 March 2024
Individuals with mood disorders are predisposed to metabolic dysfunction, while those with metabolic dysregulation such as diabetes and obesity experience more severe depressive symptoms. Both metabolic dysfunction and mood disorders are independently associated with cognitive deficits. Therefore, given their close association, this study aimed to explore the association between metabolic dysfunction in individuals with mood […]
Maksyutynska, Kateryna
Reward anticipation-related neural activation following cued reinforcement in adults with psychotic psychopathology and biological relatives 10 January 2024
BackgroundSchizophrenia is associated with hypoactivation of reward sensitive brain areas during reward anticipation. However, it is unclear whether these neural functions are similarly impaired in other disorders with psychotic symptomatology or individuals with genetic liability for psychosis. If abnormalities in reward sensitive brain areas are shared across individuals with psychotic psychopathology and people with heightened […]
Demro, Caroline
Weight change in people with depression and the risk of dementia: a nationwide cohort study 5 January 2024
BackgroundDepression is a risk factor for dementia and weight change can appear as a symptom of depression. However, the association between weight change after the diagnosis of depression and the risk of dementia is poorly established. This study aimed to investigate the association between weight change before and after a diagnosis of depression with the […]
Kim, Hyewon

Alcohol use disorder and risk of specific methods of suicide death in a national cohort 2 May 2024
Acta Psychiatrica Scandinavica, Volume 149, Issue 6, Page 479-490, June 2024.
Alexis C. Edwards, Linda Abrahamsson, Casey Crump, Jan Sundquist, Kristina Sundquist, Kenneth S. Kendler
A comprehensive analysis of age of onset and cumulative incidence of mental disorders: A Danish register study 2 May 2024
Acta Psychiatrica Scandinavica, Volume 149, Issue 6, Page 467-478, June 2024.
Christoffer Beck, Carsten Bøcker Pedersen, Oleguer Plana‐Ripoll, Søren Dalsgaard, Jean‐Christophe Philippe Debost, Thomas Munk Laursen, Katherine Louise Musliner, Preben Bo Mortensen, Marianne Giørtz Pedersen, Liselotte Vogdrup Petersen, Zeynep Yilmaz, John McGrath, Esben Agerbo
Decreased oxytocin levels related to social cognition impairment in borderline personality disorder 2 May 2024
Acta Psychiatrica Scandinavica, Volume 149, Issue 6, Page 458-466, June 2024.
Alejandra Galvez‐Merlin, José M. López‐Villatoro, Pilar de la Higuera‐González, Alejandro de la Torre‐Luque, Karina McDowell, Marina Díaz‐Marsá, Juan C. Leza, José L. Carrasco

Implementation of the International Classification of Diseases 11th revision behavioural indicators for disorders of intellectual development with co‐occurring autism spectrum disorder 11 May 2024
Journal of Intellectual Disability Research, EarlyView.
K. R. Lemay, C. S. Kogan, T. Rebello, J. W. Keeley, R. Bhargava, S. Buono, S. Cooray, P. Ginige, M. T. Kishore, J. V. S. Kommu, M. Recupero, A. Roy, P. Sharan, G. M. Reed
Soft cerebellar signs unveil RARS2‐related epilepsy 11 May 2024
Epileptic Disorders, EarlyView.
Vidal Yahya, Robertino Dilena, Roberto Del Bo, Manuela Magni, Fabio Biella, Sabrina Salani, Francesco Fortunato, Elisa Scola, Alessio Di Fonzo, Edoardo Monfrini
Prescribing patterns in patients with obsessive‐compulsive disorder: Retrospective, single‐center study 11 May 2024
Human Psychopharmacology: Clinical and Experimental, EarlyView.
Joshua Knebel, M. Lindsey Hedgepeth Kennedy

A role for Shugoshin in human cilia?
We have recently described a novel role for the conserved centromeric/kinetochore protein and cohesin protector, Shugoshin, in cilia of C. elegans. Worms are unusual in that the sole Shugoshin protein ( SGO-1 ) is dispensable for chromosome segregation but required for cilia function in fully differentiated sensory neurons. Depletion of sgo-1 leads to an array […]
sut-2 loss of function mutants protect against tau-driven shortened lifespan and hyperactive pharyngeal pumping in a C. elegans model of tau toxicity.
Expression of human tau in C. elegans neurons causes progressive, age-associated loss of motor coordination, selective neurodegeneration, and shortened lifespan. Loss of function (LOF) mutations in the conserved gene sut-2 protects against progressive motor uncoordination and neurodegeneration in models of tauopathy. To determine whether sut-2 LOF also protects against shortened lifespan of tau transgenic C. […]
Evidence Based Clinical Analytics Supporting the Genetic Addiction Risk Severity (GARS) Assessment to Early Identify Probands in Preaddiction.
No abstract supplied.

Beyond Psychopharmacology: the Interpersonal Dynamics of Agitation Management
Practical Advice for Preventing Problems When Referencing the Literature
Provision of Cognitive Behavior Therapy for Depression and Anxiety Disorders by Medical Student Trainees
The purpose of the article is to evaluate an innovative education program in which medical students were trained in cognitive behavior therapy (CBT) and provided CBT treatments under supervision to uninsured individuals with depressive, anxiety, adjustment, and trauma-based disorders.The authors assessed improvements in trainees’ CBT knowledge using the Cognitive Therapy Awareness Scale before and after […]

Web-Based Initiatives to Prevent Sexual Offense Perpetration: A Systematic Review
Web-based programs to prevent sexual offense perpetration could provide an opportunity that avoids many of the barriers associated with in-person treatment. The aim of this systematic review is to give an overview of the literature on web-based initiatives aimed at sexual offense perpetration prevention published during the last 10 years (2013–2023) and to report data on […]
Attachment Theory and Sexual Offending: Making the Connection
The purpose of this review is to discuss how attachment theory can be applied to explain sexual violence. Specifically, it discusses how the development of certain risk factors contributes to these behaviors and how attachment-based models can be used to address this issue through prevention and therapeutic interventions.Recent research demonstrates that individuals who commit sexual […]
Dynamic Protective Factors Relevant to Sexual Offending
Focusing on protective factors rather than risk factors potentially better aligns assessment with strengths-based treatment. We examine research into the assessment of protective factors to see whether it can play this role relative to sexual offending.Structured asses sment of protective factors is well developed relative to violent offending but only recently studied relative to sexual […]

Editorial introductions 26 March 2024
No abstract available
Urbanization and psychosis: an update of recent evidence 4 March 2024
Purpose of review Urbanization, a complex global phenomenon, has a significant bearing on schizophrenia/psychosis burden through various socioeconomic and environmental factors. This review focuses on recent evidence (2019–2023) linking urbanization, schizophrenia, and the role of green space. Recent findings This review analyzed 43 articles that examined the correlation between urban birth or upbringing, urban living […]
Shifting the paradigm of social withdrawal: a new era of coexisting pathological and non-pathological hikikomori 28 February 2024
Purpose of review Social withdrawal syndrome, known as “hikikomori,” has been highlighted since the late 1990 s in Japan. Hikikomori is more common in urban areas, and often comorbid with mental disorders, and now spreading throughout the world. In the post-COVID-19 era, not outing is no longer considered pathological in itself as the “new normal,” and […]

When is the best time to screen for perinatal anxiety? A longitudinal cohort study
For screening for anxiety during pregnancy and after birth to be efficient and effective it is important to know the optimal time to screen in order to identify women who might benefit from treatment.To determine the optimal time to screen for perinatal anxiety to identify women with anxiety disorders and those who want treatment. A […]
Daily-level associations between posttraumatic stress disorder symptoms and reactions to retrieving positive autobiographical memories
Trauma survivors with posttraumatic stress disorder (PTSD) report difficulties accessing and describing positive memories. To understand these patterns, we examined daily-level relations of PTSD symptoms with affective, cognitive (dwelling/rumination; pushing memory out of one’s mind; suppression; avoidance; distraction; thinking about something else; remembering negative or positive memories/events; negative or positive thoughts; accepting or disapproving memory; […]
Relationship between anxiety sensitivity and post-traumatic stress symptoms in trauma-exposed adults: A meta-analysis
Given the high rate of trauma exposure among the general population, it is important to delineate the risk factors for post-traumatic stress disorder (PTSD). While historically implicated in panic disorder, anxiety sensitivity is increasingly found to play a role in PTSD. The present review investigated the size of the relationship between anxiety sensitivity and PTSD […]

‘I'm still su!c!dal when you're done with the paperwork’: an inductive framework thematic analysis of #camhs on TikTok 10 May 2024
Journal of Child Psychology and Psychiatry, EarlyView.
Molly Foster, Hannah Frith, Mary John
Practitioner Review: Assessment and treatment of body dysmorphic disorder in young people 9 May 2024
Journal of Child Psychology and Psychiatry, EarlyView.
Georgina Krebs, Daniel Rautio, Lorena Fernández de la Cruz, Andrea S. Hartmann, Amita Jassi, Alexandra Martin, Argyris Stringaris, David Mataix‐Cols
Examining variability in Naturalistic Developmental Behavioral Intervention strategy use in caregivers of children with autism spectrum disorders 9 May 2024
Journal of Child Psychology and Psychiatry, EarlyView.
Hallie Brown, Deanna Swain, Hye Won Kim, Sally Rogers, Annette Estes, Connie Kasari, Catherine Lord, So Hyun Kim

All medical workers together: For better mental health and primary health care- Posters 29 April 2024
The International Journal of Psychiatry in Medicine, Volume 59, Issue 3_suppl, Page 1S-103S, May 2024.
Physical, psychological, cultural, and pharmacological factors influencing the treatment of patients in primary care settings 25 April 2024
The International Journal of Psychiatry in Medicine, Volume 59, Issue 3, Page 267-269, May 2024.
Harold G Koenig
Psychosocial effects of hidradenitis suppurativa in the literature: A systematic review 22 April 2024
The International Journal of Psychiatry in Medicine, Ahead of Print. Hidradenitis suppurativa (HS) is an inflammatory disorder characterized by painful, deep follicular nodules, abscesses, sinus tracts, and scarring, most commonly presenting in the inguinal, axillary, and anogenital regions. This condition substantially decreases quality of life in affected individuals, resulting in higher rates of psychiatric disorders […]
Elizabeth Richards

Measurement of perceived pressures in psychiatry: paper-and-pencil and computerized adaptive version of the P-PSY35 scale 10 May 2024
Formal coercion in psychiatry is widely studied yet much less is known about pressures patients may experience, partly because of the very few measures available. The goal of this study was to validate the P-P...
Philippe Golay, Debora Martinez, Mizué Bachelard, Benedetta Silva, Alexandra Brodard, Jonathan Perrin, Nolan Pedro Fernando, Lou-Ann Renaud, Charles Bonsack and Stéphane Morandi
Item analysis on the quality of life scale for anxiety disorders QLICD-AD(V2.0) based on classical test theory and item response theory 10 May 2024
Anxiety disorders can cause serious physical and psychological damage, so many anxiety scales have been developed internationally to measure anxiety disorders, but due to the cultural differences and cultural ...
Hongqiang Shi, Yu Ren, Junding Xian, Haifeng Ding, Yuxi Liu and Chonghua Wan
Cortical activation for adolescent-onset minor depression and major depressive disorder: an fNIRS study 9 May 2024
While depression is increasing worldwide, some patients are diagnosed as having Major Depressive Disorder (MDD), but others are diagnosed with minor depression, however, the potential neuro mechanism is unknown.
Gaizhi Li, Ke Ma, Kathryn Rossbach, Ying Niu, Qiqi Li, Zhifen Liu and Kerang Zhang

Psychiatry International, Vol. 5, Pages 205-216: How Moral Distress Contributes to Depression Varies by Gender in a Sample of Sub-Saharan African Nurses 6 May 2024
Although research has shown that moral distress harms mental health in diverse populations, information on potential moderators of such associations is scarce. In a sample of sub-Saharan African nurses, we examined the link between moral distress and depressive symptoms. We explored for whom and when such relationships may hold with regard to gender, age, and […]
JohnBosco Chika Chukwuorji
Psychiatry International, Vol. 5, Pages 188-204: “Once Again It Becomes a Friend in Times of Adversity”: A Qualitative Exploration of Interrelationships between Anorexia Nervosa and Trauma over Ten Years 30 April 2024
Background: The majority of research on the relationship between anorexia nervosa (AN) and trauma has been cross-sectional and quantitative. This study aimed to qualitatively explore how this relationship may shift over time. Methods: A community sample of nine women with a lived experience of AN and trauma were interviewed three times over ten years (1997–2007). […]
Sallee Berry
Psychiatry International, Vol. 5, Pages 169-187: Depressive Disorders and EU Labour Resources—The Problem of Lost Productivity in Highly Developed Economies 16 April 2024
Research has shown that mental disorders in working-age individuals are associated with a significant burden of disability, sickness absence, and presenteeism, resulting in lost productivity. This study aims to assess the impact of depressive disorders on the labour markets in the European Union countries, with a particular focus on the disparities between the ‘old’ and […]
Agnieszka Jakubowska

Blighted phenomena: Learning to work with the dark. 8 April 2024
Blighted phenomena are understood as derivatives of dark, lonely, injured experiences—those that are often difficult to put into words. These phenomena can manifest in innumerable configurations in patients’ presentations and in the specificity of their developmental struggles and language. The present article aims to describe ways of working with the darkness of blighted experience, through […]
Intimate partner violence: Narratives of attachment relationships and linguistic analysis of emotional schemas through a quali-quantitative approach. 18 January 2024
Intimate partner violence (IPV) is a concerning, widespread issue with serious health, social, and financial consequences. Previous studies highlighted the role of insecure attachment patterns in predicting IPV victimization. This study investigates attachment classifications among women survivors of IPV referred to antiviolence centers, as determined by the Adult Attachment Interview and compare them with a […]
Review of Reading French Psychoanalysis. 25 December 2023
Reviews the book, Reading French Psychoanalysis edited by Dana Birksted-Breen, Sara Flanders, and Alain Gibeault (2010). In this essay, the author discusses eight reviews of Reading French Psychoanalysis. The reviews considered are Cheshire (2010) in the British Journal of Psychotherapy, Forde (2010) in the Revista de Psicoanálisis, Glassgold (2014) in the Psychoanalytic Quarterly, Lefer (2011) […]

Leveraging natural language processing to study emotional coherence in psychotherapy. 18 January 2024
The association between emotional experience and expression, known as emotional coherence, is considered important for individual functioning. Recent advances in natural language processing (NLP) make it possible to automatically recognize verbally expressed emotions in psychotherapy dialogues and to explore emotional coherence with larger samples and finer granularity than previously. The present study used state-of-the-art emotion […]
Bridging the multicultural orientation framework with sexual and gender minority psychotherapy: A mixed studies systematic review. 11 January 2024
Sexual and gender minorities (SGM) experience higher rates of psychological distress and seek psychotherapy at higher rates compared to their heterosexual and cisgender counterparts. However, few therapists are trained on how to provide effective psychotherapy with SGM clients. The multicultural orientation (MCO) framework, which has been linked to improved therapeutic processes and outcomes, may be […]
Validation of the German version of the Comparative Psychotherapy Process Scale. 30 November 2023
The Comparative Psychotherapy Process Scale (CPPS) is a 20-item scale which aims to capture technical features distinguishing cognitive behavioral (CBT) from psychodynamic (PD) psychotherapy (and vice versa) in two corresponding subscales (CBT and PD Subscale). Our objective was to validate a German self-report version of the CPPS regarding a previous psychotherapy session in a psychotherapist- […]

An examination of semantic performance in mild cognitive impairment progressors and nonprogressors. 15 February 2024
Objective: Mild cognitive impairment (MCI) is a risk factor for developing Alzheimer’s disease (AD), and about half of older people with MCI will progress to AD within the next 5 years. The aim of the present study was to compare the semantic performance of MCI progressors (MCI-p) and nonprogressors (MCI-np). The hypothesis was that MCI-p […]
Processing speed in first episode of psychosis and first-degree relatives: A candidate endophenotype of spectrum schizophrenia disorders. 8 February 2024
Objective: The processing speed (PS) is highly impacted in individuals experiencing their first episode of psychosis (FEP). Conducting family studies can help to determine whether PS can serve as an endophenotype of schizophrenia spectrum disorders (SSDs), offering valuable insights into the prevention and diagnosis of SSDs. Method: A comprehensive cognitive battery, encompassing tests for PS, […]
Association between neuropsychological assessment and amyloid status in a clinical setting. 8 February 2024
Objective: Large research cohorts show robust associations between neuropsychological tests and Alzheimer’s disease (AD) biomarkers, but studies in clinical settings are limited. The increasing availability of AD biomarkers to the practicing clinician makes it important to understand the relationship between comprehensive clinical neuropsychological assessment and biomarker status. This study examined concordance between practicing clinical neuropsychologists’ […]

Group identity modulates interbrain synchronization during repeated lottery contest. 11 January 2024
Overbidding in Tullock (1980) lottery contests is a robust finding in laboratory experiments. There exists plenty of evidence that demonstrates the effect of group identity on human behavior. This presents a viable avenue for mitigating or resolving the issue of overbidding. However, the impact of group identity on interbrain interactive mechanisms during lottery contests remains […]
Neurosciences tell us how to be adaptable, creative, and proactive agents in decision making: A pilot study. 7 December 2023
In organizational settings, the decision-making process plays a pivotal role and is interrelated with the capability to adapt to the context, that is, adaptability. In this study, the behavioral, electrophysiological (EEG) frequency bands (i.e., alpha, theta) and self-report correlates of adaptability in the context of decision making were explored on a sample of professionals and […]
Modulating the activity of right temporoparietal junction increased belief-based learning in an economic game. 7 December 2023
Decision making is fundamental to social and economic behavior in the presence of other competing intelligent agents. Such decisions require agents to learn about available rewards and punishments (involving reinforcement learning) and also to anticipate what opponents intend to do (involving belief-based learning). However, the neural mechanisms underlying belief-based learning are relatively poorly understood. To […]

The cost-effectiveness of mental health interventions amongst prison populations: a systematic review (research letter to the editor) 11 May 2024
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Aleix RowlandsonGemma ShieldsElise BlakemoreIniyah SulamanCharlotte LennoxRebecca CrookDavid HoneywellDaniel Pratta Manchester Centre for Health Economics, Division of Population Health, Health Services Research and Primary Care, School of Health Sciences, Faculty of Biology, Medicine and Health, University of Manchester, UKb EPIC Learning and Psychology Service, Doncaster City Council, UKc REVIVE Partnership, East Lancashire Teaching Hospitals Trust, Burnley, UKd Division of Psychology and Mental Health, Faculty of Biology, Medicine and Health, Health and Justice Research Network, University of Manchester, UKe Centre for New Treatments and Understanding in Mental Health (CeNTrUM), Division of Psychology and Mental Health, Faculty of Biology, Medicine and Health, University of Manchester, UKf Public Health, Policy & Systems, Institute of Population Health, Faculty of Health and Life Sciences, University of Liverpool, UKg School of Criminal Justice, Arden University, Coventry, UKh Greater Manchester Mental Health NHS Foundation Trust, School of Health Sciences, Faculty of Biology, Medicine and Health, University of Manchester, UK
Patients as educators in medical student education in forensic psychiatry: a scoping review of the barriers and facilitators 7 May 2024
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Leila ShardaMurwah YasirLouise Robinsona Medical Education, Lancashire and South Cumbria NHS Foundation Trust, Preston, UKb The Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UKc Guild Lodge, Lancashire and South Cumbria NHS Foundation Trust, Preston, UK
Using technologies to evaluate response style in the competency crisis recommendations for evaluators 3 May 2024
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Graham DanzerForensic Services Division, State of Florida, DCF United States, Orlando, FL, USA

Experts' decision-making processes in Swedish forensic psychiatric investigations: A case vignette study
It has previously been demonstrated that decisions made by forensic experts can suffer from issues with both bias and poor reliability. The outcome of Swedish forensic psychiatric investigations can have a major impact on the courts' choice of sanction for a mentally disordered offender. These investigations are performed by multi-professional teams of experts, where each […]
Efficiency of psychological interventions in the prevention of suicidal behavior and self-injury in penitentiary population: A systematic review
Suicidal behavior is an important public health problem, with a high prevalence in penitentiary context. Nowadays, there is a wide variety of specific treatment programs, aimed to prevent suicidal and self-injurious behavior in incarcerated people. These programs show relative efficiency depending on the model of the psychological intervention applied. This systematic review evaluates the efficiency […]
Compulsory treatment in Portuguese-speaking countries: An analysis and comparison of the legal framework
Compulsory treatment involves the hospital admission of individuals with mental disorders in appropriate facilities through judicial decisions. However, limited information is available regarding the similarities and differences in compulsory treatment legislation in Portuguese-speaking countries.To analyse the commonalities and differences in compulsory treatment legislation in Portuguese-speaking countries, where Portuguese is the primary official language, including Angola, […]

Cocaine and the port: Utopias of security, urban relations, and displacement of policing efforts in the port of Piraeus
In large commercial seaports policing and security efforts to counter the drug trade, especially cocaine, do not appear to be effective beyond a mere displacement effect. In the port of Piraeus, Greece, (perceived) rising quantities of cocaine have led to calls for further securitisation of the port to curb illicit trafficking. This article will present […]
Individual and environmental contributors to psychological distress during imprisonment
People in prison bear a higher burden of psychiatric morbidity compared with the general population. This study examined the extent to which individual and environmental factors contribute to poor mental health during imprisonment. Participants comprised 1296 randomly selected adults in 15 Belgian prisons. Psychological distress was more common in women than men and peaked during […]
Origin stories: Framing 25 years of Dutch political discourse on child sexual exploitation by tourists and travelers
Sexual exploitation of children in the context of travel and tourism (SECTT) has been described as a serious and growing problem. This study critically analyzes political debates and policy measures proposed by the Dutch government between 1995 and 2020 to combat SECTT. To understand how SECTT is framed in Dutch political discourse, Bacchi's ‘what's the […]

Correction to “Gentrification’s association with police violence and the moderating effects of race” by Harmon-Darrow et al. (2023). 2 May 2024
Reports an error in "Gentrification’s association with police violence and the moderating effects of race" by Caroline Harmon-Darrow, Hyun-Jin Jun and Charlotte Lyn Bright (Psychology of Violence, 2023[May], Vol 13[3], 183-193). In the article, corrections to some findings were needed. For the Gentrification Revitalization × Race and the Gentrification Disruption × Race interactions (reported in […]
Perceived victimhood shapes support for interpartisan political violence in the United States. 21 March 2024
Objective: Understanding the drivers of political violence is critical, given the destructive consequences it has on the fabric of society. Prior work has established the importance of situational and dispositional predictors of political violence, such as search for significance and meaning and experiencing trauma. However, these predictors do not fully account for one of its […]
Sexual victimization of autistic college students. 18 March 2024
Objective: Researchers have demonstrated a link between autism and victimization, but less research has explored rates of sexual victimization among autistic college students. Informed by lifestyle-routine activity theory, certain features of autism may enhance vulnerability to sexual victimization and may lead autistic individuals to be targeted by potential perpetrators. Method: Using data from the American […]

Web‐based intervention for young adults experiencing anxiety and hazardous alcohol use: Study protocol for an 18‐month randomized controlled trial 10 May 2024
Addiction, EarlyView.
Katrina Prior, Andrew J. Baillie, Nicola Newton, Yong Yi Lee, Mark Deady, Tara Guckel, Laura Wade, Ronald M. Rapee, Jennifer L. Hudson, Frances Kay‐Lambkin, Tim Slade, Mary Lou Chatterton, Cathrine Mihalopoulos, Maree R. Teesson, Lexine A. Stapinski
Gambling participation and risk after COVID‐19: Analysis of a population representative longitudinal panel of Australians 10 May 2024
Addiction, EarlyView.
Aino Suomi, Jeffrey Kim, Markus H. Hahn, Nicholas Biddle
Para‐fluorofentanyl: Coincidence or intentional? 9 May 2024
Addiction, EarlyView.
Jeremy R. Canfield, Kristin V. Canfield, Jon E. Sprague

Tobacco use, trauma exposure and PTSD: a systematic review 7 May 2024
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Alina ShevorykinBridget M. HylandDaniel RoblesMengjia JiDarian VantucciLindsey BenschHannah ThornerMatthew MarionAmylynn LiskiewiczEllen CarlJamie S. OstroffChristine E. Sheffera Department of Health Behavior, Roswell Park Comprehensive Cancer Center, Buffalo, NY, USAb Department of Psychology, Faculty of Science, University of Alberta, Edmonton, Canadac Department of Psychology, The City College of New York (CUNY), New York, NY, USAd Department of Psychiatry and Behavioral Sciences, Memorial Sloan Kettering Cancer Center, New York, NY, USA
Development of the social dimensions of health behaviour framework 29 April 2024
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Ryan E. RhodesMark R. Beauchampa Behavioural Medicine Laboratory, School of Exercise Science, Physical and Health Education, University of Victoria, Victoria, BC, Canadab School of Kinesiology, University of British Columbia, Vancouver, BC, Canada
A systematic review of the studies testing the integrated motivational-volitional model of suicidal behaviour 16 April 2024
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Kenvil SouzaEdward M. SosuScott ThomsonSusan Rasmussena Department of Psychological Sciences and Health, University of Strathclyde, Glasgow, UKb Strathclyde Institute of Education, University of Strathclyde, Glasgow, UK

Representing the experiences of charity peer leaders facilitating well-being interventions to their peers using a constructivist grounded theory methodology 13 May 2024
This study aims to generate theory that represented charity peer leader experiences, facilitating well-being interventions to two specific groups of people: new mothers and refugees. Part 1 of this study used in-depth interviews (n = 8) and phone calls with experienced mothers (called “peer leaders”) who had facilitated well-being interventions to new mothers. These interviews […]
Jenny Burns
It’s not just a game: social networks, isolation and mental health in online gamers 8 May 2024
Online gaming has emerged as a popular activity providing a social outlet for millions. However, implications of online game networks for mental health remain disputed. Concepts of bridging social capital and bonding social capital may help characterize protective factors within social networks. This study aims to examine the associations between social capital derived from online […]
Tyler Prochnow
Domestic violence against women during COVID-19 pandemic and its associated factors among Bench Sheko zone, southwest Ethiopia 19 April 2024
Domestic violence is an intimate relationship that causes physical, sexual or mental suffering. The ongoing coronavirus pandemic has had a ruinous effect globally, particularly in increasing the rate of domestic violence. Thus, this study aims to assess the prevalence of domestic violence against women during the COVID-19 pandemic and its associated factors. A community-based cross-sectional […]
Gebremeskel Mesafint

‘Early childhood autism, Asperger type’, by H. Asperger (1982) 29 April 2024
History of Psychiatry, Ahead of Print. After his 1944 thesis, Asperger continued to write about autism, but none of these texts have been translated. At a time when autism spectrum disorder faces many challenges (e.g. the nature and measurement of autism), this text tells us more about the particular population that Asperger worked with. He […]
Kevin Rebecchi
Landmarks in the history of neurosyphilis: the neglected observations of Vincenzo Chiarugi 24 April 2024
History of Psychiatry, Ahead of Print. After the emergence of syphilis in Europe in 1495, it would take over 400 years to unpick the full course of the infection, including the involvement of the brain and spinal cord. This syndrome of mental and physical deterioration was called ‘general paralysis of the insane’ (GPI). Traditionally, the […]
Daniel Di Francesco
Historical and conceptual features of acute polymorphic psychosis: a myth of European psychiatry from bouffée délirante to ICD-11 acute and transient psychotic disorder 20 April 2024
History of Psychiatry, Ahead of Print. This paper deals with the history and epistemology of acute polymorphic psychosis. We undertook a comparative study of short-lived psychotic disorders used in different European countries since the late nineteenth century. The theory of degeneration offered a speculative basis to conceptualization of conditions such as bouffée délirante, cycloid psychosis […]
Augusto C Castagnini

In memoriam António Bento (1954–2023): Champion of the loveless homeless in Portugal, veteran member of Santé Mentale et Exclusion Sociale (SMES) in Europe 30 April 2024
International Journal of Social Psychiatry, Ahead of Print.
João Gama Marques
The community health worker experience and perception toward mental illness: A multi-settings cross-sectional study in Indonesia 29 April 2024
International Journal of Social Psychiatry, Ahead of Print. Background:The experiences and perceptions of Community Health Workers toward mental illness are vital for tailoring interventions, reducing stigma, improving access to services, and fostering community engagement in mental health initiatives.Aims:This study investigates the experiences of community health worker and their perception of mental illness.Methods:A multi-settings cross-sectional study […]
Marthoenis Marthoenis
Disease, illness, phenomenology and narratives 16 April 2024
International Journal of Social Psychiatry, Volume 70, Issue 3, Page 413-414, May 2024.
Dinesh Bhugra

Investigating the spatial and temporal variation of vape retailer provision in New Zealand: A cross-sectional and nationwide study
Deprived areas experienced an unjust presence of vape retailers.Significant inequity in access to vape stores by deprivation, ethnicity and urbanicity.29% of schools in New Zealand have a vape store within 5-min walking distance.Pacific students and those in major urban areas have the easiest access to vape stores. Smoking rates have decreased in Aotearoa New Zealand […]
The problematic nature of existing explanations for differential immigrant mortality: Insights from a comparative cross-national systematic review and meta-analysis
Empirical studies in multiple disciplines have frequently observed an immigrant mortality advantage. Yet, questions remain regarding the possible mechanisms underlying this phenomenon. We obtained data from 61 studies of relative immigrant mortality from single origin-destination country pairings, providing information on immigrants from 77 origin countries. We systematically review the arguments made in these studies about […]
Discursive trends in New York Times coverage of Evusheld access: A case study in the social production of ignorance
coverage of preventative treatment Evusheld rarely discusses access barriers.Access barriers discussed are largely logistical rather than structural.The perspectives of immunocompromised people are rarely included in articles on Evusheld.Failure to include voices from impacted communities contributes to agnogenesis.Centering the perspectives of constituencies most impacted by a health crisis will advance health equity. English-language reporting on the […]

When my neighborhood woke up: Knitting collective action in disadvantaged areas amid the 2019 Chilean uprising. 15 April 2024
October 2019 saw the birth of the largest wave of demonstrations to hit Chile in the last 50 years. Protesters, the length of the country, soon joined in, voicing a broad range of demands and driving what has been described as a true “awakening” at the local level. This local dimension of the protests—that is, […]
Clarification notice to “The geography of military occupation and its effect on Palestinian community cohesion, norms, and resistance motivation” by Penić et al. (2023). 15 April 2024
Reports a clarification to "The Geography of Military Occupation and its Effect on Palestinian Community Cohesion, Norms, and Resistance Motivation" by Sandra Penić, Johanna Ray Vollhardt, Karsten Donnay, Mai Albzour and Ravi Bhavnani (Peace and Conflict: Journal of Peace Psychology, Advanced Online Publication, Jun 22, 2023, np). The authors wish to clarify the relationship between […]
School as a contested territory for citizenship: An ethnographic study of illegal occupation and protest processes at a popular vocational education school in the chilean october. 15 April 2024
The sociopolitical crisis that flared up in Chile starting in October 2019 laid bare tensions in how different social groups understand citizenship and political mobilization. These tensions evinced clear generational differences coupled with the emergence of new forms of understanding and doing politics among youth. This article presents the results of an ethnographic study conducted […]

Concretization as a possible mechanism of nightmare proneness: Some theoretical considerations and empirical findings. 28 March 2024
Nightmare proneness, a disposition to experience frequent nightmares, has been found to predict nightmares independent of neuroticism, psychological distress, and trauma symptoms. One theorized mechanism of nightmare proneness is concretization, a hypothetical defensive style in which vague and unpleasant inner states are made more tangible. The possible role of concretization in nightmare proneness and nightmares […]
Nightmare types and suicide. 28 March 2024
Previous research has robustly documented the relationship between sleep and suicide, where many aspects of poor sleep quality, sleep disturbances, and sleep disorders have been found to predict suicide. Research has also linked nightmares to suicide. It is not known, however, if nightmare types (idiopathic, trauma-related, and complex nightmares [nightmares with comorbid sleep and breathing […]
Veteran treatment completers’ and facilitators’ perceptions of cognitive behavioral therapy for insomnia and imagery rehearsal therapy for posttraumatic sleep disturbances. 13 November 2023
Cognitive behavioral therapy for insomnia (CBT-I) and imagery rehearsal therapy are recommended cognitive-behavioral treatments. However, little is known about the acceptability of the treatments for veterans with posttraumatic sleep disturbances. This study was conducted after a pilot randomized controlled trial that compared CBT-I with CBT-I combined with imagery rehearsal therapy (IRT) in a sample of […]

Beach Boys' Brian Wilson Needs Conservatorship Due to Mental Decline, Judge Finds 10 May 2024
(MedPage Today) -- A judge found Thursday that Beach Boys founder and music luminary Brian Wilson should be in a court conservatorship to manage his personal and medical decisions because of what his doctor calls a "major neurocognitive disorder...
APA Roundup: Depression & Loss of Joy; Long-COVID Brain; Mood Disorders & Suicide 9 May 2024
(MedPage Today) -- NEW YORK CITY -- Some of the latest research advancements in the field of psychiatry presented at the American Psychiatric Association annual meeting this year included an LSD-containing drug for anxiety, psychiatric issues...
Fraudulent Practices Abound in Post-Accident Healthcare 9 May 2024
(MedPage Today) -- Car accidents are an unfortunate reality of modern life, often leading to personal injury cases involving a range of medical professionals, from chiropractors to physical therapists, pain doctors, and personal injury lawyers...

Shirley Winters being sent to secure psychiatric facility after release from prison - YouTube 11 May 2024
Shirley Winters being sent to secure psychiatric facility after release from prison. No views · 3 minutes ago ...more ...
Elevated SCN11A concentrations associated with lower serum lipid levels in patients with ... 11 May 2024
All MDD patients enrolled from the First Affiliated Hospital of Chongqing Medical University's Department of Psychiatry. As antidepressants may ...
OHSU Pulls Psychiatry Fellows From County's Troubled Jails - Willamette Week 11 May 2024
The Forensic Psychiatry Fellowship program has played an integral role in providing badly needed mental health care in the county's jail.

Bangladesh: Heat Wave - Apr 2024 21 April 2024
Affected country: Bangladesh Glide: HT-2024-000056-BGD Based on the Bangladesh Meteorological Department (BMD) data source dated 21 April 2024, severe to very severe, heatwave was sweeping some districts of the country where mild-moderate heatwave was sweeping over most of the districts of the country. BDRCS forecast monitoring report indicates maximum temperatures exceeding to 38 degree Celsius, […]
Kyrgyzstan: Floods and Landslides - Apr 2024 20 April 2024
Affected country: Kyrgyzstan Glide: FL-2024-000053-KGZ Since 20 April, heavy rainfall has been affecting the regions of Osh, Jalal-Abad and Talas (southern and eastern Kyrgyzstan) triggering several landslides, causing floods and resulting in casualties and damage. According to media, one person died on 20 April due to a landslide, while hundreds have been evacuated following floods […]
Rwanda: Floods - Apr 2024 20 April 2024
Affected country: Rwanda Glide: FL-2024-000064-RWA In Rwanda, heavy rains and floods killed 14 people in Nyanza District, injured 27 in Burera District and damaged roads, bridges and 123 houses since 28 April and as of 2 May. Several hectares of rice and banana plantation in Ruhango District have been damaged, according to local authorities. Heavy […]

9th Meeting of the Strategic and Technical Advisory Group of Experts (STAGE) for Maternal, Newborn, Child and Adolescent Health and Nutrition (MNCAHN) 13 May 2024
Ninth meeting of the Strategic and Technical Advisory Group of Experts (STAGE) for Maternal, Newborn, Child and Adolescent Health and Nutrition (MNCAHN)
who.int
NCD Hard Talks webinar: From pockets to patients: Rethinking how we can reduce out-of-pocket expenditure for NCD medicines 8 May 2024
To prevent patients from paying too much out of their own pockets, we have to ensure equitable access to NCD medicines and technologies with affordable and effective financing.
who.int
Introducing the ARIA tool – Indoor Airborne Risk Assessment 8 May 2024
This session, organized jointly by CERN and WHO, will introduce a new model designed to quantify the risk of airborne transmission of SARS-CoV-2, the virus that causes COVID-19, alongside an associated online tool. This event marks the first in a series of webinars scheduled for 2024, aimed at exploring further uses of the tool across various […]
who.int

WHO Regional Director Dr Hanan Balkhy concludes her first visit to Pakistan 7 May 2024
Islamabad, 7 May, 2024 – WHO's Regional Director for the Eastern Mediterranean, Dr Hanan Balkhy, has concluded her inaugural visit to Pakistan. The comprehensive five-day mission spanned Islamabad, Peshawar and Lahore, and included high-level meetings with government officials, visits to WHO-supported health facilities, and participation in the subnational polio vaccination campaign. This was also Dr […]
Rafah incursion would substantially increase mortality and morbidity and further weaken an ... 3 May 2024
3 May 2024 – WHO is deeply concerned that a full-scale military operation in Rafah could lead to a bloodbath. More than 1.2 million people are currently sheltering in the area, many unable to move anywhere else. A new wave of displacement would exacerbate overcrowding, further limiting access to food, water, health and sanitation services, leading to […]
50 years of EPI’s extraordinary impact on global health 1 May 2024
24 April 2024, Cairo, Egypt – World Immunization Week this year coincides with the 50th anniversary of the Expanded Programme on Immunization (EPI). Such has been the programme’s remarkable impact on global health that the “E” in EPI today stands for “Essential”. Since 1974, this WHO initiative has inspired countries to use vaccines to do […]

Disasters Forced 2.5 Million Americans From Their Homes Last Year 22 February 2024
Many of those displaced also reported food shortages and predatory scams, according to new data from the Census Bureau.
Aidan Gardiner
U.S. Hit by Record Number of High-Cost Disasters in 2023 19 February 2024
There were 28 storms, wildfires or other disasters that each cost at least one billion dollars in damages, a sign of the growing economic burden of climate change.
Christopher Flavelle
Biden Offers Aid to California as It Deals with Floods and Mudslides 6 February 2024
The president addressed the public via Los Angeles Mayor Karen Bass’s speakerphone to offer aid from FEMA after a deadly atmospheric river hit the state.

Impact of yoga on the central and peripheral vascular function among desk-based workers: A single-centered trial study [version 2; peer review: awaiting peer review] 10 May 2024
Background The aim of this study was to observe and analyze vascular function in ‘prolonged sitting’, followed by a yoga asana routine and pranayama intervention. Participants in this study include those who work from desks in offices. The study required the participants to attend on three separate days at random, and they had to finish […]
Poovitha Shruthi P
Case Report: Uterine artery embolization after dysfunctional uterine bleeding due to incomplete abortion in female [version 1; peer review: awaiting peer review] 10 May 2024
Dysfunctional uterine bleeding (DUB), a serious clinical challenge caused by incomplete abortion in female, calls for efficient and minimally invasive therapies to treat symptoms and protect reproductive health. Uterine artery embolization (UAE) has been discovered as a viable therapeutic strategy to treat DUB following an incomplete abortion. The existing information and clinical experience of UAE […]
Sagar Jha
Efficacy of POWERbreathe Medic Plus device on maximal inspiratory pressure, functional capacity and quality of life in coronary artery bypass graft patients: A randomized controlled trial protocol [version 1; peer review: awaiting peer review] 10 May 2024
Coronary artery disease (CAD) is a prominent cause of illness and mortality worldwide, with a significant amount of coronary artery bypass graft (CABG) surgeries performed each year. It is a complicated technique that results in several clinical and functional issues. While CABG is an effective treatment, it comes with clinical and functional challenges, including reduced […]
Vishnu Vardhan

Medicines eligible for Northern Ireland MHRA Authorised Route 10 May 2024
Sets out medicines that can be moved to Northern Ireland to meet patient need.
HM Government
Child death reviews: forms for reporting child deaths 10 May 2024
Forms to help child death overview panels (CDOPs) assess the causes of a child’s death as part of the child death review process.
HM Government
NHS primary medical service directions 9 May 2024
This collection brings together directions for the National Health Service primary medical services, setting out part of the legal framework under which GP practices operate and are paid.
HM Government

Measuring wellbeing and going ‘Beyond GDP’ 9 May 2024
A new ONS publication out today, aims to give an holistic view on how society is doing, beyond purely economic measures. Here, Tim Vizard explores what we have done so far on Beyond GDP and outlines our next steps on this important work.
samcollin
Understanding the new income statistics for local areas: Different measures for better insights 30 April 2024
The ONS has been busy producing faster, more detailed statistics using new data sources. Providing clearer insights at the local level is an important aspect of this work. Ainslie Woods explains how our local income statistics compare and why they offer a complementary picture of local areas.
croydl
Exploring findings from the Winter COVID-19 Infection Study 25 April 2024
In November 2023 ONS and UK Health Security Agency (UKHSA) launched the Winter COVID-19 Infection Study (Winter CIS) to gather vital data on levels of the virus in the colder months. James Tucker explores some of the findings and takes a deeper look at what they can tell us about ongoing symptoms and risk factors.
lornatipper

Pregnant women in UK offered extra opportunity to screen for Edwards’ syndrome 10 May 2024
The UK National Screening Committee has recommended including a test for Edwards’ syndrome as part of the fetal anomaly screening programme for women who miss, or do not complete, the first trimester combined test.1The committee agreed that the quadruple test is accurate enough to be added to the antenatal screening pathway for Edwards’ syndrome but […]
Jacqui Wise
Continuous observation of patients at risk of self harm is often ineffective, finds safety report 10 May 2024
There is only limited evidence that the current approach to continuous observation of patients at risk of harming themselves when on hospital wards is effective, an investigation has concluded.1The report from the Health Services Safety Investigations Body (HSSIB) said that sometimes healthcare providers get false reassurance from a patient being on continuous observation, believing that […]
Jacqui Wise
Health department lacks grip on spending and clinical negligence payouts, MPs warn 10 May 2024
Value for money checks over NHS spending are shrouded in uncertainty owing to audit delays, weaknesses in financial systems, and backlogs, MPs have said. The Commons public accounts committee also raised concerns about the level of money spent on settling clinical negligence cases, which hit £2.6bn in the most recent year.A report from the committee, […]
Adrian O’Dowd

Oral Microbiome Test Could Detect Gastric Cancer Earlier 10 May 2024
An oral rinse shows distinct differences in the microbiomes of people with pre-gastric or gastric cancer compared with controls, suggesting the possibility of a new tool for early detection. Medscape Medical News
What to Consider When Prescribing Lecanemab 10 May 2024
The risks and benefits of lecanemab therapy were highlighted at the recent American Geriatrics Society conference. Medscape Medical News
If at First Tirzepatide Doesn't Succeed, Keep Trying 10 May 2024
Treatment guidelines that advise stopping a weight-loss drug if weight loss isn't achieved by 12 weeks don't account for the titration required, investigator says. Medscape Medical News

Working It Out: How to Minimize Eczema Flare-ups at the Gym and on the Job 11 May 2024
Three keys to managing your eczema at the gym and then heading off to a productive and itch-free workday.
Cows Are Potential Spreaders of Bird Flu to Humans 10 May 2024
Cow udders have the same receptors for flu viruses as humans and birds, raising concerns that cows could become “mixing vessels” that help the bird flu virus spread between people.
Age-Related Macular Degeneration: Putting a Hole in Our World 10 May 2024
Estimates show that by 2040, age-related macular degeneration may affect nearly 300 million people worldwide. And we are very limited in our ability to treat or prevent it. Here's what to know.

Navigating the complex relationship between palliative care and MAiD 6 May 2024
On this episode of the CMAJ Podcast, Dr. Blair Bigham and Dr. Mojola Omole explore the intricate relationship between medical assistance in dying (MAiD) and palliative care in Canada. They focus on a qualitative study titled "Perspectives of Canadian healthcare leaders on the relationship between medical assistance in dying and palliative and end-of-life care services: […]
Canadian Medical Association Journal
Confronting the high stakes of incivility in health care 22 April 2024
On this episode of the CMAJ Podcast, Dr. Eve Purdy makes it clear what’s at stake when it comes to incivility in medicine. "It's very simple. Incivility kills patients, and that needs to be the single line of every healthcare leader responsible for managing and leading teams.” Dr. Purdy joins Dr. Sarah Kim and hosts, […]
Canadian Medical Association Journal
Diagnosis and treatment of anorexia nervosa in adolescent males 8 April 2024
On this episode of the CMAJ Podcast, Dr. Blair Bigham and Dr. Mojola Omole closely examine anorexia nervosa in male adolescents, a topic that frequently escapes notice. Their discussion highlights the disorder's prevalence, especially among high-risk groups like LGBTQ+ individuals and those from varied racial and ethnic backgrounds. It also underscores the severity of anorexia […]
Canadian Medical Association Journal

World News in Brief: Vaccine ‘patches’ trial shows promise, lowering catheter infection risk, Guantanamo detainee facing revictimisation 9 May 2024
Few enjoy having injections and if you have children, you probably like them even less when it’s time for their mandated vaccine shots.
No sign yet of H5N1 bird flu spreading between humans, says WHO chief 8 May 2024
The H5N1 avian influenza virus has so far shown no signs of adapting to allow human-to-human transmission, the UN health agency said on Wednesday, urging continued surveillance.
Patients in Rafah ‘afraid to seek services’, WHO reports 7 May 2024
The World Health Organization (WHO) has taken “crucial steps” in preparation for a large-scale Israeli military operation in Rafah, Dr. Ahmed Dahir, team lead of its office in Gaza, told UN News on Tuesday.