Evidence
Cureus. 2023 Jun 23;15(6):e40847. doi: 10.7759/cureus.40847. eCollection 2023 Jun.
ABSTRACT
Disorders of sperm production can be classified quantitatively as oligospermia (low sperm count) or azoospermia (no sperm during ejaculation). Numerous genes have been implicated in spermatogenesis. We describe a case of two identical twins who presented with different reproductive capabilities. One brother was infertile due to azoospermia, and the other, although oligospermic, previously naturally fathered a child. They were found to have differential gene expression based on RNA sequencing analysis. In the man with azoospermia, we found elevated E2F1 and HOXB9 gene expressions when compared with his brother, suggesting that the increased RNA expression of these genes could influence sperm production.
PMID:37492809 | PMC:PMC10363651 | DOI:10.7759/cureus.40847
Add to Google Keep
Estimated reading time: 2 minute(s)
Latest: Psychiatryai.com #RAISR4D
Cool Evidence: Engaging Young People and Students in Real-World Evidence ☀️
Real-Time Evidence Search [Psychiatry]
AI Research [Andisearch.com]
Transcriptional Differences in Identical Twins With Different Reproductive Capacities: A Case Report
🌐 90 Days
VR Related Evidence Matrix
- Artificial intelligence: to a better predictive strategy for testicular sperm extraction outcome in azoospermia
- Trans Species RNA Activity: Sperm RNA of the Father of an Autistic Child Programs Glial Cells and Behavioral Disorders in Mice
- Age-related and species-specific methylation changes in the protein-coding marmoset sperm epigenome
- Genetic contribution to microglial activation in schizophrenia
- Student Seminar
- Automated Single-Sperm Selection Software (SiD) during ICSI: A Prospective Sibling Oocyte Evaluation
- Transarterial Embolization for Cystic Artery Pseudoaneurysm Caused by Hepatocellular Carcinoma Rupture in the Gallbladder: A Case Report
- Contextual and combinatorial structure in sperm whale vocalisations
- Adrenal Gland Incidentaloma: A Rare Case of Extranodal B-cell Lymphoma
- The Leukemoid Reaction in Severe Alcoholic Hepatitis: A Case Report
- A Somatic-Type Delusional Disorder Resulted in Severe Weight Loss With a Body Mass Index of 10.2: A Case Report
- Outcomes of Anorexia Nervosa in a Male Patient Treated With Paroxetine: A Case Report
- Transcriptional signatures of fentanyl use in the mouse ventral tegmental area
- Scrotal Dermatofibrosarcoma Protuberans in a Patient with Schizophrenia: A Case Report and Review of the Literature
- Unveiling the Chameleon: A Case Report on Acute Intermittent Porphyria
- Very Low-Dose Sublingual Ketamine for Borderline Personality Disorder and Treatment-Resistant Depression
- Epigenetics of Genes Preferentially Expressed in Dissimilar Cell Populations: Myoblasts and Cerebellum
- Improvement in Selective Serotonin Reuptake Inhibitor-Associated Sexual Dysfunction With Buspirone: Examining the Evidence
- A Case of Rhabdomyolysis Induced by Antipsychotic Medication With Creatine Kinase (CK) Levels Elevated to 420,000 U/L, Resulting in Acute Kidney Injury (AKI) and Necessitating Hemodialysis
- Spinal Deformity Manifested by Urinary Tract Infection: A Case of Acute-on-Chronic Mobility Dysfunction
- Recurrent Acute-on-Chronic Pancreatitis in a Chronic Alcoholic With Pancreatic Divisum: A Complex Case
- A Case of Severely Impaired Consciousness and Convulsions From Attempted Suicide by Ingesting Triflumizole Emulsion: Clinical Features and Literature Review
- Comparative transcriptome analysis between rhesus macaques ( Macaca mulatta) and crab-eating macaques ( M. fascicularis)
- Knee Buckling as an Atypical Adverse Effect of Clozapine: A Case Report
- Choosing Appropriate Nutritional Therapy for Patients With Anorexia Nervosa Exhibiting Liver Dysfunction: A Case Report
- Borderline Personality Disorder With Atypical Traits in a 30-Year-Old Female: A Case Report
- Borderline Personality Disorder With Atypical Traits in a 30-Year-Old Female: A Case Report
- Impact of Multimodal Rehabilitation Protocol in a 20-Year-Old Patient With Cherubism Undergone Facial Surgery: A Rare Case Report
- The impact of water pollution on the health of older people
- Posterior Reversible Encephalopathy Syndrome Presenting as Delirium With Psychosis and Agitation in the Postpartum Period
- Schizencephaly Associated With Bipolar Affective Disorder
- Bilateral juvenile osteochondrosis dissecans in monozygotic twins: a case report
- Twins Standing in for Co-Twins: Explanation and Speculation/Twin Research Reviews: Single v. Multiple Embryo Transfer; Neurimaging of Twins with Periventricular Nodular Heterotopia; Twin Dietary Study; New Hungarian Text on Twins/Human…
- Identification of a molecular network regulated by multiple ASD high risk genes
- Portal Vein Thrombosis With Hypoplasia in the Left Lobe of the Liver: A Case Report
- Successful Challenge With Brexpiprazole for Idiopathic Hypersomnia in a Patient With Bipolar Disorder: A Case Report
- Prenatal Ultrasound Diagnosis of Vasa Previa With Careful Intraoperative Management: A Case Report
- Effect of Osteopathic Manipulation in an Autism Spectrum Child With Speech Impairment and Attention Deficit: A Case Report
- Dysphagia in a Patient With Lewy Body Dementia and Incidental Anterior Cervical Osteophyte: A Case Report
- Non-cirrhotic Ascites: A Case of Severe Alcoholic Hepatitis
- Acute Pancreatitis Secondary to Cocaine Intoxication: A Case Series
- Diagnostic Challenges and Treatment Approach to Seronegative Autoimmune Encephalitis
- Massive Pilomatrixoma of the Scalp: A Case Report
- Uncommon Scurvy Manifestation: Solitary Skin Lesion in an Alcoholic Case
- Knockdown of SCN5A alters metabolic-associated genes and aggravates hypertrophy in the cardiomyoblast
- Genetics of environmental sensitivity to psychiatric and neurodevelopmental phenotypes: evidence from GWAS of monozygotic twins
- Longitudinal Changes of Regional Cerebral Blood Flow on a Single-Photon Emission Computed Tomography (SPECT) Scan in a Patient With Schizophrenia Having Cotard's Syndrome
- A Case of Postpartum Obsessive-Compulsive Disorder in a First-Time Father
- Utilization of sperm cryopreservation in patients with testicular cancer
- MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons
- Anti-N-Methyl-D-Aspartate Receptor Encephalopathy in a Young Female
- Decreased Volume of Bone Marrow Adipocytes With Sparse Gelatinous Marrow Transformation in a Patient With Pancytopenia With Anorexia Nervosa: A Case Report
- Decreased Volume of Bone Marrow Adipocytes With Sparse Gelatinous Marrow Transformation in a Patient With Pancytopenia With Anorexia Nervosa: A Case Report
- Optic Neuropathy as a Rare Ocular Complication of Acute Pancreatitis: A Case Report
- Methadone Withdrawal-Induced Psychosis: A Case Report
- Kratom-Induced Psychiatric Decompensation and Paranoid Delusions
- A Rare Case of Disseminated Histoplasmosis Involving the Colon and Brain
- A Case of Risperidone-Induced Urinary Incontinence
- Ensemble Learning for Higher Diagnostic Precision in Schizophrenia Using Peripheral Blood Gene Expression Profile
- Neurological Resilience in Patients With Anorexia Nervosa Following Prolonged Cardiopulmonary Resuscitation
- A Rare Presentation of Laurence-Moon-Bardet-Biedl Syndrome: Atypical Retinitis Punctata Albescens and Non-alcoholic Fatty Liver Disease
- Transcriptomics of Human Brain Tissue in Parkinson's Disease: a Comparison of Bulk and Single-cell RNA Sequencing
- Severe Shewanella Cellulitis Following Saltwater Exposure in an Elderly Patient
- History Is the Key to Diagnosis: A Case of Nitrofurantoin-Induced Interstitial Lung Disease
Evidence Blueprint
Transcriptional Differences in Identical Twins With Different Reproductive Capacities: A Case Report
☊ AI-Driven Related Evidence Nodes
(recent articles with at least 5 words in title)
More Evidence
Transcriptional Differences in Identical Twins With Different Reproductive Capacities: A Case Report
🌐 365 Days
VR Related Evidence Matrix
- Artificial intelligence: to a better predictive strategy for testicular sperm extraction outcome in azoospermia
- Trans Species RNA Activity: Sperm RNA of the Father of an Autistic Child Programs Glial Cells and Behavioral Disorders in Mice
- Transposon insertion profiling by sequencing (TIPseq) identifies novel LINE-1 insertions in human sperm
- Age-related and species-specific methylation changes in the protein-coding marmoset sperm epigenome
- Investigating the impact of paternal aging on murine sperm miRNA profiles and their potential link to autism spectrum disorder
- Genetic contribution to microglial activation in schizophrenia
- Hypokalemic Hypophosphatemic Thyrotoxic Periodic Paralysis Associated with Bipolar Disorder Therapy
- Treating a Case of First-Episode Psychosis to Uncover Undiagnosed Obsessive Compulsive Disorder: A Case Report
- Chronic Alcoholism and Its Health Implications: A Case Report
- Immunohistochemical Expression of Ki-67, Dopamine D1 and Dopamine D2 Receptors in Meningiomas in a Tertiary Institution in Mexico
- Protective efficacy of Nerium oleander extract on spermatogenesis in streptozotocin-induced diabetic rats
- Anti-Müllerian hormone predicts positive sperm retrieval in men with idiopathic non-obstructive azoospermia-findings from a multi-centric cross-sectional study
- Student Seminar
- Complete Remission of Advanced Hepatocellular Carcinoma in a Patient With Ulcerative Colitis Treated With Atezolizumab and Bevacizumab: A Case Report
- Automated Single-Sperm Selection Software (SiD) during ICSI: A Prospective Sibling Oocyte Evaluation
- A Case Report: Lithium-Induced Neurotoxicity, a Differential to Always Consider
- The effect of smoking and electronic cigarettes on rat testicles
- Homicide-Suicide Partners: A Simulation of Injuries
- The Intertwined Relationship Between an Overactive Thyroid and an Overactive Mind: A Case Report and Review of Literature
- Evening type negatively affects semen quality by deteriorating sperm morphology: Results from an infertility clinic
- A Case of Autoimmune Pancreatitis Presenting As Alcohol-Induced Necrotizing Pancreatitis
- Wilson Disease: Uncommon but Not to Be Forgotten
- Lithium-Induced Bradycardia and Cardiomyopathy in a Patient With Bipolar Disorder and Paranoid Schizophrenia
- Chronic Administration of Lisdexamfetamine Induces Apoptosis and Inflammation and Reduces Sperm Quality in Adult Male Rats
- Lithium-Induced Arginine Vasopressin Resistance (AVP-R): A Case of Chronic Exposure to Lithium
- Neurosyphilis-Induced Folie À Deux: A Case of Prolonged Psychosis
- Bipolar Disorder Due to Traumatic Brain Injury: A Case Report
- Subependymal Giant Cell Astrocytoma Non-Associated With Tuberous Sclerosis Complex and Expression of OCT-4 and INI-1: A Case Report
- Schwannoma and Post-vaccine Changes: A Case Report
- Dementia and mortality in older adults: A twin study
- Wernicke Encephalopathy in a Patient With Bipolar Disorder: A Case Report
- Icy Intrigue: A Case Report of an Unusual Encounter With an Ice Pick Injury
- A Case of Hypernatremia With Dementia
- A systematic review of non-coding RNA genes with differential expression profiles associated with autism spectrum disorders
- Transarterial Embolization for Cystic Artery Pseudoaneurysm Caused by Hepatocellular Carcinoma Rupture in the Gallbladder: A Case Report
- Contextual and combinatorial structure in sperm whale vocalisations
- Colloid Cyst Presenting With Severe Headache and Bilateral Leg Weakness: Case Report and Review
- Adrenal Gland Incidentaloma: A Rare Case of Extranodal B-cell Lymphoma
- Abdominal Ecchymosis: Emergency, or Urgen-C?
- Adenocarcinoma of an Unknown Primary Site: Presentation, Diagnosis, and Management
- Retraction: The Development of Illness Anxiety Disorder in a Patient After Partial Thyroidectomy
- Oculogyric Crisis Due to Aripiprazole Ingestion as a Suicide Attempt: A Case Report
- Differential variability analysis of single-cell gene expression data
- Cauda Equina Neuroendocrine Tumor: A Histopathological Case Report
- Neuro-Behçet With a Thalamic Lesion: A Case Report
- The Leukemoid Reaction in Severe Alcoholic Hepatitis: A Case Report
- A Rare Presentation of Narcolepsy With Cataplexy After Vaccines in a Genetically Susceptible Elderly Woman: A Case Report
- Overlapping Phenotypes of Alcoholic Cardiomyopathy and Left Ventricular Non-compaction: A Case Report and Discussion of Converging Cardiomyopathies
- A Somatic-Type Delusional Disorder Resulted in Severe Weight Loss With a Body Mass Index of 10.2: A Case Report
- Old Drugs and New Challenges: A Narrative Review of Nitazenes
- A Case of Hypertriglyceridemia-Induced Acute Pancreatitis in the Setting of Alcohol Abuse
- High-Intensity Statin Therapy and Associated Rhabdomyolysis in Chronic Liver Disease: A Case Report and Review of Literature
- Outcomes of Anorexia Nervosa in a Male Patient Treated With Paroxetine: A Case Report
- Lemierre's Syndrome Caused by Klebsiella pneumoniae: A Case Report and Literature Review
- A Case of Acute Catatonia Precipitated by Psychosis Successfully Treated With Lorazepam: A Case Report
- Transcriptional signatures of fentanyl use in the mouse ventral tegmental area
- Sexual, reproductive and mental health among young men (10-24) in low-and-middle income countries: a scoping review
- Postpartum Psychosis as a Consequence of Thyroiditis Versus Relapse: A Diagnostic Dilemma
- Reconstruction of Trauma Dynamics Due to Ligature Strangulation by Using a Dynamometer: A Technical Report
- Biphasic Peritoneal Mesothelioma Is a Rare Tumor and a Diagnostic Challenge: A Case Report
- Effects of paternal and chronological age on BEGAIN methylation and its possible role in autism
- Fatal Curiosity: A Case of Suicidal Attempt by Abrus Seeds Consumption Through Online Research
- Hepatic Encephalopathy Caused by Long-Term Amiodarone Use
- Scrotal Dermatofibrosarcoma Protuberans in a Patient with Schizophrenia: A Case Report and Review of the Literature